LOCUS       NM_001413659            1342 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus spermatogenesis and oogenesis specific basic
            helix-loop-helix 1 (Sohlh1), mRNA.
ACCESSION   NM_001413659 XM_017591875
VERSION     NM_001413659.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Shin,Y.H., Ren,Y., Suzuki,H., Golnoski,K.J., Ahn,H.W., Mico,V. and
            Rajkovic,A.
  TITLE     Transcription factors SOHLH1 and SOHLH2 coordinate oocyte
            differentiation without affecting meiosis I
  JOURNAL   J Clin Invest 127 (6), 2106-2117 (2017)
   PUBMED   28504655
REFERENCE   2  (bases 1 to 1342)
  AUTHORS   Barrios,F., Filipponi,D., Campolo,F., Gori,M., Bramucci,F.,
            Pellegrini,M., Ottolenghi,S., Rossi,P., Jannini,E.A. and Dolci,S.
  TITLE     SOHLH1 and SOHLH2 control Kit expression during postnatal male germ
            cell development
  JOURNAL   J Cell Sci 125 (Pt 6), 1455-1464 (2012)
   PUBMED   22328502
REFERENCE   3  (bases 1 to 1342)
  AUTHORS   Suzuki,H., Ahn,H.W., Chu,T., Bowden,W., Gassei,K., Orwig,K. and
            Rajkovic,A.
  TITLE     SOHLH1 and SOHLH2 coordinate spermatogonial differentiation
  JOURNAL   Dev Biol 361 (2), 301-312 (2012)
   PUBMED   22056784
REFERENCE   4  (bases 1 to 1342)
  AUTHORS   Choi,Y., Yuan,D. and Rajkovic,A.
  TITLE     Germ cell-specific transcriptional regulator sohlh2 is essential
            for early mouse folliculogenesis and oocyte-specific gene
            expression
  JOURNAL   Biol Reprod 79 (6), 1176-1182 (2008)
   PUBMED   18753606
REFERENCE   5  (bases 1 to 1342)
  AUTHORS   Ballow,D., Meistrich,M.L., Matzuk,M. and Rajkovic,A.
  TITLE     Sohlh1 is essential for spermatogonial differentiation
  JOURNAL   Dev Biol 294 (1), 161-167 (2006)
   PUBMED   16564520
REFERENCE   6  (bases 1 to 1342)
  AUTHORS   Pangas,S.A., Choi,Y., Ballow,D.J., Zhao,Y., Westphal,H.,
            Matzuk,M.M. and Rajkovic,A.
  TITLE     Oogenesis requires germ cell-specific transcriptional regulators
            Sohlh1 and Lhx8
  JOURNAL   Proc Natl Acad Sci U S A 103 (21), 8090-8095 (2006)
   PUBMED   16690745
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 8, 2022 this sequence version replaced XM_017591875.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.1721107.1,
                                           SRR26643293.15433.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               JAXUCZ010000003.1  29065384-29065588   c
            206-340             JAXUCZ010000003.1  29064941-29065075   c
            341-488             JAXUCZ010000003.1  29064417-29064564   c
            489-613             JAXUCZ010000003.1  29063859-29063983   c
            614-711             JAXUCZ010000003.1  29063501-29063598   c
            712-898             JAXUCZ010000003.1  29062689-29062875   c
            899-975             JAXUCZ010000003.1  29062128-29062204   c
            976-1342            JAXUCZ010000003.1  29061267-29061633   c
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1342
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /note="spermatogenesis and oogenesis specific basic
                     helix-loop-helix 1"
                     /db_xref="GeneID:362085"
                     /db_xref="RGD:1564440"
     exon            1..205
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1178
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /codon_start=1
                     /product="spermatogenesis- and oogenesis-specific basic
                     helix-loop-helix-containing protein 1"
                     /protein_id="NP_001400588.1"
                     /db_xref="GeneID:362085"
                     /db_xref="RGD:1564440"
                     /translation="MASGGHERATEDYGVSDITGCSKTPQTETQENLETPSQSSALCP
                     APVAAANWSPCLRRNVVSERERRRRISLSCERLRALLPQFDGRREDMASVLEMSVCFL
                     QLAHSMDPSWEQLSVPQPPQEMWHMWQGDVLQVTLANQIADSKPDSGIAKASAVARVQ
                     DPPCCGMLDTDQSQATERASELLERPSSCPESSSLGAGLPPWPPHSWQPATPEASDAV
                     SGGSQQVGSLAGDTESPGMLAEEANLVLASVPDARYTTGAGSEVVDGASFLLTTNPDW
                     WLGSVEGRGGPALARNSPVDGAEPIYIGDPEPCSQELQAGPVELWGLDFGSPGLALKD
                     EADSIFPDFFP"
     exon            206..340
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            341..488
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            489..613
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            614..711
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            712..898
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            899..975
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1342
                     /gene="Sohlh1"
                     /gene_synonym="RGD1564440"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcatgagagt gggcagccag gcgctggttg gatgcggagc tcctgtgggt aggcagagtg
       61 tgggcgagag ggcgggcagg tgggcagagc tagggccatc tgtggcttcc agcttgttgc
      121 ttccctccaa ctttgttcca atggcgtccg gtggccacga gcgggctact gaggattacg
      181 gagtctccga cattacggga tgcagcaaga ctcctcagac tgagactcag gagaacttgg
      241 agactccctc acaaagctca gccctctgcc cagctcctgt ggctgctgca aattggagcc
      301 cctgtcttcg gagaaacgtg gtcagcgaga gagaacgcag gaggaggatc tccttgagct
      361 gtgagcgctt gcgggcacta ctgcctcagt ttgatggccg tcgggaggac atggcttccg
      421 tcctggagat gtctgtgtgt ttcctccagc ttgcccacag catggatcct agctgggagc
      481 agctctctgt tcctcagcct cctcaagaga tgtggcacat gtggcagggc gatgttctgc
      541 aggtaaccct tgcgaatcag attgcagaca gcaagccaga ctccgggata gcaaaagcat
      601 ctgccgtggc tcgggtgcag gaccccccat gctgtggcat gctggataca gaccagagcc
      661 aagctactga gagggcgtcg gagcttctgg agaggccttc ctcctgccct gagtcctcca
      721 gcttgggtgc tgggctccca ccctggcctc ctcactcatg gcagccagcc actcccgagg
      781 cgagtgacgc tgtttctggt ggatcacagc aggtgggatc cctggccggg gacactgagt
      841 ctccgggcat gctggctgag gaggccaact tggtcttggc atctgtgcct gatgccaggt
      901 acaccacagg ggcagggtcc gaagtggtgg acggagcatc ctttctgctg accaccaatc
      961 ctgattggtg gttggggtca gtggagggca gaggaggacc agctcttgcc aggaacagcc
     1021 cagtggatgg ggcagagcca atctacattg gagaccctga gccctgctcc caggagctcc
     1081 aggctggccc cgtagagctg tggggcttgg attttggcag ccctggcctg gccctgaagg
     1141 atgaagcaga cagcatcttc cctgactttt tcccctgatg gcttagttgc cccatagttt
     1201 agtttgctgg gagagctatc ccttgcctgg gtgttgtatt ttgggtttgg tttgcagctg
     1261 cagcctaatt tgaggaaggc tggcaggact atgagtggag tttgtattaa agagaaaagt
     1321 ggtttttctg gcagaagcaa aa
//
