LOCUS       NM_001107256            2037 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus suppressor of cytokine signaling 4 (Socs4), mRNA.
ACCESSION   NM_001107256 XM_001073326 XM_223934
VERSION     NM_001107256.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2037)
  AUTHORS   Sun SL, Li TJ, Yang PY, Qiu Y and Rui YC.
  TITLE     Modulation of signal transducers and activators of transcription
            (STAT) factor pathways during focal cerebral ischaemia: a gene
            expression array study in rat hippocampus after middle cerebral
            artery occlusion
  JOURNAL   Clin Exp Pharmacol Physiol 34 (11), 1097-1101 (2007)
   PUBMED   17880360
REFERENCE   2  (bases 1 to 2037)
  AUTHORS   Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N,
            Rechavi G and Yarden Y.
  TITLE     Suppressors of cytokine signaling 4 and 5 regulate epidermal growth
            factor receptor signaling
  JOURNAL   J Biol Chem 280 (8), 7038-7048 (2005)
   PUBMED   15590694
REFERENCE   3  (bases 1 to 2037)
  AUTHORS   Wormald S and Hilton DJ.
  TITLE     Inhibitors of cytokine signal transduction
  JOURNAL   J Biol Chem 279 (2), 821-824 (2004)
   PUBMED   14607831
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168879.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001107256.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168879.1, EV763137.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2037
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..2037
                     /gene="Socs4"
                     /note="suppressor of cytokine signaling 4"
                     /db_xref="GeneID:305828"
                     /db_xref="RGD:1306503"
     exon            1..78
                     /gene="Socs4"
                     /inference="alignment:Splign:2.1.0"
     exon            79..2015
                     /gene="Socs4"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1482
                     /gene="Socs4"
                     /codon_start=1
                     /product="suppressor of cytokine signaling 4"
                     /protein_id="NP_001100726.1"
                     /db_xref="GeneID:305828"
                     /db_xref="RGD:1306503"
                     /translation="MAENNSKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSRKSESCS
                     ESEAVGTLESVEIPLRSQERELSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPI
                     RNCGARHSPGLPSKRTIHISELMLDKCPFPPPSDLAFRWHFIKRHTVALSSSSDEWVS
                     TDLCERRPRDAQLKRRSTEDDIPCFSHTSVQPCVITTNSASCAGGHVTGSLMNLVTDN
                     SMEDGDMDSEDEIITLCTSSRKRNKPRWETDDGILQLEAPPKFHTQIDYVHCLVPDLL
                     QISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQ
                     WNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRT
                     VICNCTTYDGIDALPIPSPMKLYLKEYHYKSKVRLLRIDVPEPQ"
ORIGIN      
        1 cttgagcgag cgccgggtga tggcgatggt gatggcggca gtccctcgga cagctccggt
       61 tgagctgtgc tcagagagat ccgtcaagaa agtgcccaga agaaacctcc tctcagaaaa
      121 tctgaaaaca cagtatttat aacactggaa attgtaaaga attcatttaa aatggctgaa
      181 aacaatagta aaaatgtaga tgtgcggcct aaaacaagtc ggagtagaag tgctgacagg
      241 aaggacggtt atgtgtggag tggaaagaag ttatcttggt ccagaaagag tgagagctgt
      301 tctgagtctg aggccgtagg tactcttgag agcgttgaaa tccctctgag gagccaggaa
      361 agggaactta gctgttcgtc cattgagttg gacttggatc attcctgtgg gcatagattt
      421 ttaggccgat cccttaaaca gaaactgcaa gatgccgtgg ggcagtgttt tcctataagg
      481 aactgtggtg ctcgccactc tccagggctt ccatctaaaa gaacgattca catcagtgag
      541 ctcatgctag acaagtgccc tttcccacct ccatcagact tagcctttag gtggcatttt
      601 attaaacggc acactgttgc tctgagttcc agttcagatg aatgggtgag cacagacctg
      661 tgtgagagga ggccgagaga tgctcagctg aaacgaagaa gcacagaaga cgacataccc
      721 tgtttctcac ataccagtgt ccagccgtgt gtcataacta ccaacagtgc ttcatgtgca
      781 ggtggtcatg tgaccggttc tctgatgaac ttggtcaccg acaatagcat ggaagacggt
      841 gatatggact cagaggatga aattataaca ctgtgcacaa gctccaggaa aaggaacaag
      901 cccagatggg aaacggatga cggcatcctg caattggagg cacctcctaa gttccacacc
      961 cagattgatt acgtgcactg ccttgtccca gacctcctcc agatcagtaa caacccgtgc
     1021 tactgggggg ttatggacaa atacgcagcc gaggctctgc tagaaggaaa gccagagggc
     1081 acctttttac ttcgagattc agcccaggaa gattatttat tctctgttag ttttaggcgc
     1141 tacagtcgtt ctcttcacgc tagaattgaa cagtggaatc ataacttcag ctttgacgcc
     1201 cacgatccct gtgtcttcca ttctcccgat attactgggc tcctagagca ttataaggac
     1261 ccaagtgcct gcatgttctt tgagccactt ttatccactc cgttaatccg gactttcccc
     1321 ttttccttgc agcacatttg caggacagtt atttgtaact gtacaacgta cgatggcatc
     1381 gatgcccttc caattccttc tcctatgaaa ttgtacctga aggaatacca ttacaaatca
     1441 aaagttaggc tactcaggat tgacgtgcca gagccacagt gacgtggaga ggttagaatg
     1501 tccacccgcg aacataggtt cattcaatag ttcatttttc ttatgcctct ttgaattttt
     1561 gtacaaaggc agttggaatc caaaataaaa ccgtgcccta agttttaatt ccagatcaat
     1621 tttttttttc tgatagactt gttatatttt aagcaggtga ttcgtttttg tttttaccat
     1681 gtaaattgta tacttttcct ttaatttgca tatggtccag gcacatttgc aatttcaagg
     1741 catcgagtac acatttgaat attctgtatt tttttaaaca atcttatgct ctttcctacg
     1801 tgtgaaatag tttgctaatc tatgctgtca gtgttcttat ctgacagaat ggttacctat
     1861 cctctttatt ttgaaactct ttagtaaaga tgagcattat aatcaaccca ttacaatgta
     1921 actgattttt gtcatttgct aatagggatg ttaaacaaca aaatgattta aaatggagct
     1981 taacatattt tccttttaaa tattaactaa aacaaaaaaa aaaaaaaaaa aaaaaaa
//
