LOCUS       NM_001127550            2411 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus sorting nexin 4 (Snx4), mRNA.
ACCESSION   NM_001127550 XM_001072295 XM_340997
VERSION     NM_001127550.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2411)
  AUTHORS   Sander,L.E., Frank,S.P., Bolat,S., Blank,U., Galli,T., Bigalke,H.,
            Bischoff,S.C. and Lorentz,A.
  TITLE     Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not
            VAMP-2 or VAMP-3, are required for activation-induced degranulation
            of mature human mast cells
  JOURNAL   Eur J Immunol 38 (3), 855-863 (2008)
   PUBMED   18253931
REFERENCE   2  (bases 1 to 2411)
  AUTHORS   Traer,C.J., Rutherford,A.C., Palmer,K.J., Wassmer,T., Oakley,J.,
            Attar,N., Carlton,J.G., Kremerskothen,J., Stephens,D.J. and
            Cullen,P.J.
  TITLE     SNX4 coordinates endosomal sorting of TfnR with dynein-mediated
            transport into the endocytic recycling compartment
  JOURNAL   Nat Cell Biol 9 (12), 1370-1380 (2007)
   PUBMED   17994011
REFERENCE   3  (bases 1 to 2411)
  AUTHORS   Parks,W.T., Frank,D.B., Huff,C., Renfrew Haft,C., Martin,J.,
            Meng,X., de Caestecker,M.P., McNally,J.G., Reddi,A., Taylor,S.I.,
            Roberts,A.B., Wang,T. and Lechleider,R.J.
  TITLE     Sorting nexin 6, a novel SNX, interacts with the transforming
            growth factor-beta family of receptor serine-threonine kinases
  JOURNAL   J Biol Chem 276 (22), 19332-19339 (2001)
   PUBMED   11279102
REFERENCE   4  (bases 1 to 2411)
  AUTHORS   Haft,C.R., de la Luz Sierra,M., Barr,V.A., Haft,D.H. and
            Taylor,S.I.
  TITLE     Identification of a family of sorting nexin molecules and
            characterization of their association with receptors
  JOURNAL   Mol Cell Biol 18 (12), 7278-7287 (1998)
   PUBMED   9819414
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166791.1.
            
            On or before Sep 7, 2008 this sequence version replaced
            XM_340997.3, XM_001072295.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166791.1, SRR8487231.115407.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2411
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..2411
                     /gene="Snx4"
                     /note="sorting nexin 4"
                     /db_xref="GeneID:360725"
                     /db_xref="RGD:1309763"
     exon            1..149
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..1361
                     /gene="Snx4"
                     /codon_start=1
                     /product="sorting nexin-4"
                     /protein_id="NP_001121022.1"
                     /db_xref="GeneID:360725"
                     /db_xref="RGD:1309763"
                     /translation="MERVPPDPEKLLQPAPLEPLGGPGAVLEAAVGEETEGTREDVSG
                     ADTMTGNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHADGQSVLTDS
                     LWRRYSEFELLRNYLLVYYPHVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLEN
                     FLLRVASHPVLCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDK
                     RFTELRQYSDELQSVISHLLRIRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGL
                     QSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLETAAQD
                     LASKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSK
                     NLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFSKM
                     "
     exon            150..271
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            272..407
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            408..557
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            558..605
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            606..661
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            662..734
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            735..796
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            797..862
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            863..952
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1052
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1198
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1313
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..2396
                     /gene="Snx4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcagctat ggagcgggta cctccggacc ctgagaagct gttgcagcct gcacccctgg
       61 agccgctggg cggccctggc gctgtgctgg aagctgcggt cggtgaggag accgagggca
      121 cccgggaaga cgtctcaggg gccgacacga tgacaggaaa taatttttgg ttgaagaaaa
      181 tagaaatcag tgtttcagaa gccgagaaga gaactggaag aaatgccatg aacatgcaag
      241 aaacgtacac tgcttacctc attgaaacgc gctcagtaga acatgccgac ggtcagagcg
      301 tcctcacaga ctcgctgtgg cggcggtaca gtgagttcga gctgttgaga aactaccttt
      361 tagtgtacta cccacatgtc gtcgtgccac ccctcccaga aaagcgggca gagttcgtgt
      421 ggcataaact ctctgctgac aacatggatc cagactttgt ggagagacga cggataggct
      481 tagaaaactt cctcttgagg gtcgcttcac atccggtcct ctgtagagac aaaatcttct
      541 atttgtttct aacacaggaa ggtaactgga aggagactgt gaatgagact ggatttcagc
      601 tgaaggcaga ctccaggtta aaagcgctta atgcaacatt cagagtgaaa aacccagaca
      661 agagattcac ggagctgagg cagtacagcg atgagctgca gtccgtcatc tcacacctcc
      721 ttcgcatcag agccagagta gcagatcgac tgtatggtgt atataaagta catgggaatt
      781 atgggagagt ttttagtgaa tggagtgcca ttgaaaaaga aatgggtgac ggcctgcaga
      841 gtgccgggca tcacatggac gtgtatgcgt cttctattga cgatatcttg gaagacgagg
      901 agcactacgc agaccagctg aaggagtact tgttctatgc ggaagcactt cgggctgtgt
      961 gcaggaagca tgagcttatg cagtatgacc tggagacagc tgctcaggac ctggcctcca
     1021 agaagcagca gtgcgaggag ctggccactg ggactgtgag aacattctcg ttgaagggaa
     1081 tgactaccaa actctttggt caagaaactc cagagcaaag agaagcccgg ataaaggtgc
     1141 tagaggagca gataaatgaa ggggaacagc agctgaagtc taaaaatctg gaaggcagag
     1201 aatttgtgaa aaatgcatgg gctgatattg aacgcttcaa agaacaaaag aaccgggacc
     1261 taaaggaagc cctcatcagc tatgctgtca tgcagatcag catgtgcaaa aagggaattc
     1321 aggtttggac caatgctaag gaatgcttca gcaagatgta atcctgtgaa gtgacttctc
     1381 ttcaggcaaa gcgccccaaa cgaagcacaa gtacaagaaa ctcagttgct gcctgataca
     1441 taaaagccta cagagcagag cggcgttggt taagcatggt atgttcctag agcaccaaag
     1501 ggtacggctt aatgaagagt aaatgctgcc atttgaagtt ctgggactgg tgctgattcc
     1561 aaaaagttag taagatacac cgacagtctg gcttctgaag cagtgcctgc atgtcaggat
     1621 gtgagtgatc tcctgtgctc ctctcagtgc cgactgccgg atctcctcct gggagagttc
     1681 ccaagacgag gtcccctgtg gactttgtag gacccacttc tgccgcgggc ttactttatc
     1741 ttgccttaga gttgagctgt ggtttgacag agctcagcag aaccttaatc gtgaagtcta
     1801 aggttttctt ccctgttcct agatcctgta ccaactgtgg acactagaaa atgccttcag
     1861 tctgtgttcc accaagattt tgatactggt cagaaatttt atactgccaa caaataagtc
     1921 tcagcttctc agatttgcag cggaataaat tcattattat aatagaaatt gctatacaga
     1981 aagatttaat tgagcattat tattctcaaa taattgttaa cttcagtagc agcctcggtt
     2041 ccctgcctgg ccctgtgcac atggtatttc agggtagatg tagcttccat atatgagact
     2101 cagtgaacac acgtgggcca gaaccttccc cactgatgtg ctttcctatt gcctggctgt
     2161 gggttttgta aagataaatt atgttgttgt gttttaatgt gtgtttcatg tacatgttca
     2221 gaaaccaagc cttgctctgc tagcttcaga atcctaactc tgcactcatt ctttctaatg
     2281 tttcaaacta tactcagtac tgtttgacat ttgacttttt tacatgttta aaatgttgct
     2341 ggatttttgt gctgtttgcc aaacttatat aataaaggaa gtgttgtgtt tatttcaaaa
     2401 aaaaaaaaaa a
//
