LOCUS       NM_001108131            5509 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus sorting nexin 19 (Snx19), mRNA.
ACCESSION   NM_001108131 XM_001055595 XM_235940
VERSION     NM_001108131.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5509)
  AUTHORS   Mas C, Norwood SJ, Bugarcic A, Kinna G, Leneva N, Kovtun O, Ghai R,
            Ona Yanez LE, Davis JL, Teasdale RD and Collins BM.
  TITLE     Structural basis for different phosphoinositide specificities of
            the PX domains of sorting nexins regulating G-protein signaling
  JOURNAL   J Biol Chem 289 (41), 28554-28568 (2014)
   PUBMED   25148684
REFERENCE   2  (bases 1 to 5509)
  AUTHORS   Harashima S, Horiuchi T, Wang Y, Notkins AL, Seino Y and Inagaki N.
  TITLE     Sorting nexin 19 regulates the number of dense core vesicles in
            pancreatic beta-cells
  JOURNAL   J Diabetes Investig 3 (1), 52-61 (2012)
   PUBMED   24843546
REFERENCE   3  (bases 1 to 5509)
  AUTHORS   Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T,
            Ogata N, Nakamura K, Chung UI and Kawaguchi H.
  TITLE     Screening of chondrogenic factors with a real-time
            fluorescence-monitoring cell line ATDC5-C2ER: identification of
            sorting nexin 19 as a novel factor
  JOURNAL   Arthritis Rheum 60 (11), 3314-3323 (2009)
   PUBMED   19877062
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474007.2.
            
            [WARNING] On Apr 29, 2024 this sequence was replaced by
            NM_001108131.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_235940.4, XM_001055595.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5509
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..5509
                     /gene="Snx19"
                     /note="sorting nexin 19"
                     /db_xref="GeneID:315478"
                     /db_xref="RGD:1309857"
     exon            1..1548
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..2853
                     /gene="Snx19"
                     /codon_start=1
                     /product="sorting nexin-19"
                     /protein_id="NP_001101601.1"
                     /db_xref="GeneID:315478"
                     /db_xref="RGD:1309857"
                     /translation="MIIRDFVLSWYRSVSHEKTFEAEMEASMKGLVQELRRRMSIVDS
                     HALTQRVLTLCGCHLQSYIQAKGATAKEQSCPVEPSQLWDAYCQVTTPHPAMSCPTTE
                     VTYARGIVNLILKELVPKPHLETRTGRHVVVELITCNVILPLISKLSDPDWIHLILVS
                     IFSKYKQDAAQGTKPPSSPCVLEQPSVPTSLPLMVEVESLPVGKASSPVAAPVHLASS
                     EPAPSPEIEEGHEAVEGELPGMLEERKVGNNSSHFLQPDIRGPLFLCEDSELESPLSE
                     LGKETIMLMTPGNFLSHRIQDALCALDDSQALEPRDGEGSECMEGAEAEEAPGAETET
                     GTLVSMLNCPEIQIDPADKEAEQGDDASLTALLEEPEKPCLQRPSCLDKGLGSGACSL
                     EPAVPPLSLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPY
                     TLYTVKYETALSGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPK
                     KLFPDLPFGNMDSDRVEARKSLLESFLRQLCAIPEIANSEEVQEFLALNTDARIAFVK
                     KPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLR
                     FSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLQMQPAEVPD
                     KEPQQVPKESVDSGLLDKAVVSQELNKSDPGTETELADTAFDLILLLLMEQWKWLCTE
                     NMQKFLRLVFGTLVQRWLEVQVANLTCPQRWAQYLRLLRESIWPGGVLPKFPRPGRTQ
                     AQKAATEKQALQSLMGLLPDFLVEILGVHKCQLSWSLVLESFQQPLINRHLIYCLGDI
                     ILEFLDLSAAVEECAPTTSASDSPGSLKKMAVST"
     exon            1549..1687
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1788
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1908
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2039
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2136
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2317
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2318..2447
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2632
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2633..2720
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..5509
                     /gene="Snx19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtggcttc tgatccttct gtgtgcatcg ttggtagtgc tgggaggatg gctgggctcc
       61 actgccattg taggggcttc aggtcaattg cacctggaac gattcatttc aattaccacc
      121 tgccctccat gtcccgaggc agaaaggcat ctggaacagg agattaactg caccatccag
      181 atgattatcc gagacttcgt gctatcctgg tatcgttctg tgagccatga gaagacattc
      241 gaggcggaga tggaggcatc catgaaaggg ttggttcagg agcttcgaag gcggatgagc
      301 atagtggaca gccatgctct tacccagagg gttctgactc tctgtggctg tcacctgcaa
      361 agctatattc aggcgaaggg ggctactgca aaggagcaga gctgtccagt tgagccctcc
      421 cagctgtggg atgcttactg ccaggttaca actccccatc ctgccatgag ctgtcccacc
      481 actgaggtca cttacgcacg tggcattgtg aatttgatac taaaagagtt agtgcccaag
      541 ccccacctgg agactaggac cggacgccat gttgtagtcg aactcattac ttgcaatgta
      601 atcttaccgc tgatcagcaa gctatcagat cctgactgga tccaccttat acttgtgagt
      661 atcttttcca agtacaaaca ggatgcagca caaggaacta aaccccccag ctcaccctgt
      721 gtcctagagc agccctcagt gcccacatct ctgccattga tggttgaagt agagagtctg
      781 ccagtaggaa aagcatcttc tccagtagca gccccagtac acttagcctc cagtgagcca
      841 gccccctccc cagagattga agaaggccac gaagctgtag agggagagtt gcctgggatg
      901 cttgaagaga gaaaagtagg gaataactca tcccattttc tacagccaga tatccgaggc
      961 cccttgttct tgtgtgaaga ctcagaactg gagtcaccac tgtctgaact gggcaaagaa
     1021 accatcatgc tgatgacccc aggcaacttc ctttcgcaca ggattcagga tgctctgtgt
     1081 gccctagacg attcccaggc tctggagcct agggatggcg aggggtctga gtgcatggaa
     1141 ggagcagaag ctgaggaggc tccaggagca gaaacagaga caggcacgct ggtctccatg
     1201 cttaattgcc cagagatcca gattgaccca gcagacaagg aggcggagca aggagatgac
     1261 gcgtctctta cagccttgct ggaagaaccg gaaaaaccct gtctccagcg accttcgtgc
     1321 ttagacaaag gtctcggcag tggtgcgtgc tcccttgagc ctgctgtgcc tccactgtca
     1381 ctttcttcct ctccccctgg tcctctcagc tcagccacct tcagctttga gtccctgagc
     1441 agtcctgatg gcccagttgt catccagaac cttcgaatca ctggcaccat cacggcccga
     1501 gagcacagtg ggactggatt ccacccgtac acgctgtaca ccgtgaagta tgagacagcc
     1561 ctcagtggcg agaacagcag cggcctacag cagctggcct atcacaccgt aaaccgccgc
     1621 taccgggagt tcttgaatct gcagacccgc ctggaggaga aaccagatct acgaaagttt
     1681 atcaaaaacg tgaagggtcc aaaaaagctc tttccagatc ttccatttgg aaacatggac
     1741 agtgacagag tagaagcccg gaagagcctc ctggagtcat tcctgaggca actctgtgcc
     1801 attcctgaga ttgccaacag tgaggaggtg caggagttcc tcgctctgaa cacagatgct
     1861 cggattgcct ttgtcaagaa gccgttcatg gtctctcgga tagacaagat ggtggtgagt
     1921 gctatcgtgg acaccttgaa gacagcgttt cctcgctctg aaccccagag tcccacagag
     1981 gagctgagtg aagctgagaa tgagagcaag ccccagacag aaggcaagaa ggctagcaag
     2041 tccagactga ggttttcatc cagtaaaatt gcccccgcac tgagtatagc tgaggcacag
     2101 gacaagattc tgtactgcct ccaggaaggc aattcggagt cagaggtcct gtccatgtct
     2161 gggatggaat ctttcattga aaagcagaca aagttactgc aaatgcagcc agcggaagtc
     2221 ccagataaag agccccagca agtccccaaa gaatctgtgg atagtggttt gctggataaa
     2281 gctgtggtat cccaagagct caacaagagt gacccaggaa cagagacaga gttagctgac
     2341 acggccttcg atctgatcct cctgctgtta atggagcagt ggaaatggct gtgtaccgaa
     2401 aacatgcaga agttcctccg ccttgttttt ggaacgctag ttcagaggtg gctagaagta
     2461 caggtggcta atctaacatg tccccagcgc tgggcacaat acctccgcct tcttcgggaa
     2521 tctatctggc ctggtggagt gctgcccaag tttccacggc ctggaaggac tcaggcacag
     2581 aaagcagcta ctgagaagca ggctttgcag agtttgatgg gtctccttcc agatttttta
     2641 gtagaaatct tgggggtgca caagtgccag ctgagctgga gtcttgtctt ggaatcattc
     2701 cagcagcccc tcatcaacag acatttgatt tactgccttg gagacattat cctggagttc
     2761 ctagacctca gtgccgctgt tgaagagtgt gccccaacca cctctgcctc agattcccca
     2821 ggcagcctca agaagatggc ggtctccact tagccaggag ttattcacac catcttcaaa
     2881 gacttgaaaa ggagaactat tccacttcca gagcagctac gatgcctgtg ccctctggag
     2941 ctaggctagc ttagctggcc cccgtctcag ggactcagct gccctaccag gcctccctca
     3001 gtagcatgtg acagagctgc atagcctcct tgcatgtgta gctgtttcca cagtctttgg
     3061 cgtgtggatt gctgtgagga ggtcttgttt ccttgggaac agaagctatg aggcagaggc
     3121 ttttcctttg ccatctcgcc atcgtggttt gccaacagca tggccctacg cgtgcatgca
     3181 cttaatccac aatgtacaag tggtaggtaa tacagaagaa agactgtagc cagatttcct
     3241 gggaggagaa aatggtctcc tgagctctct tttcctacct ggaaactaaa cattcgttca
     3301 ggatcactcc ctcaccctgc ctagtttccc aacaattcca gaagagggaa ggaaagtatg
     3361 tctccaggga cttgctattt tctaacacag aggacttcta aggggtttca agaacactgt
     3421 ttccttgggt ggctatactt ttcctgtcct tctggcctca aagcacgatg tcaaacttct
     3481 ggtaattcca ctccaccctt cacacccttt cctgcgatgg gattacacag cagattttct
     3541 taactttcct cccagtccat acccaagagc aaatgcgttt tgaatttgta actttccctc
     3601 tatcaacagc atcacatggc aggttacgta tttggcctca gtatttccaa agagaaggga
     3661 aagtacttgt tccagggctg agggtgtaca aagaatagaa gtcagggggt ctgtggggat
     3721 ccttccacaa gactttggca agaataatat aacagacttg caggaaacag attgtagttt
     3781 ctgttcctta aagattgagt tagtccttag gagtccaaca ctaaaagcag agcgctctgt
     3841 gtccactgga aagaaggaac aactgagagc agttagaagg aaagggagtt ggaggagaag
     3901 tcacaagaga agctgctgcc cgggaaatgc agggcagcca taggagacca tagccaaccc
     3961 tcagctcagt agacctgtgt agctctggcc tggctacact aaactacggg atccacgtga
     4021 attagggtta tggagaaagc cggtgagaat tgggaaggca tcaagagcca gcatcaacac
     4081 agactctgaa gtatgtgatg aacacacaat taaagttgtt catagaaaag gggttgtgag
     4141 actgtgttac tctcctgccc tgagagattc ctaactggac attgtaatgt gactgggagg
     4201 cttgccatgc tgttcttact taaaaggaga aaacagtgaa tgagataaag tttcattgcc
     4261 tcttctggtc ttgaagcttg gcttgatgtc tccacagttc ttgaagtatc cccttcccta
     4321 ggcctgcaga gacaaaggta attcagcatg ttgtcctctg agtgcctgct agggatatgg
     4381 tttccaggga taccttagag ctgatcctgt ggctcctgga gtcaaggcta cttctgtatt
     4441 ggtggaatga gcaaccctga tttctgaaag tcttctctcc caacgcccac cccttcacat
     4501 ggccgtagcc acccgtgtgc atttgagtct gctgtcattt ctggtgcaca cacccacaaa
     4561 cactgttact aacccaacgc accatgagtt cctgtggcag tgaagtctaa ggggtctttt
     4621 cattcctgca gcccagagaa catccttatg tttcatttta tataagaggg tccattttac
     4681 tcctcctgcc ctcaaaggat aaactatcct aaagaaagaa ataatatcaa aacccatcca
     4741 gctttgaaaa agacctgtga agtttgatag cagcttcagg ccacaagatc tccatcctat
     4801 gggagagagc cactggcgtt agaatgatgc tccaggctgg aagtggaaaa gcagggagaa
     4861 ctgagcccac attggtccac ttcatttctt tcctgtttgg ccgttttaag actcagttta
     4921 ctcatttaag tcagaatatt aaaatctgaa ataagaccaa tacccattct gtcttgattg
     4981 cccatttgta gaaagatgag ggctgagtgg atactgagct ctctctggca atttctaatt
     5041 gccgtcattg ctgttaatta ttgaagttca ggaactctgt atgtaattat gtaattttat
     5101 ataagtacaa tatataatag cccacaattt ttatttctaa gcttttggat taggttttgt
     5161 agaacctaga aggaaaacac tctcctaaat ctaagcttag gaaatgtgaa atttttaaaa
     5221 ttaatggaag tttctagcat ataacatgat cttttgttgt aagggtgcca tggaattttc
     5281 tctataaaca ctgttgtaca ccacatctct agaacatttc ccttgtggat aacactatac
     5341 tcagtaaaca gcaagctccc ctgttccctg gagggcggtg gtatttgaca gtcgccattc
     5401 cacattctgt gtatgtgcat ctataaactg caagtgagtg gagttgtgta gtgtttgccc
     5461 tgtaacggac ttatttctct tggcattatg gcctcaggtt catctatgc
//
