LOCUS       NM_001107652            4394 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus sorting nexin 18 (Snx18), mRNA.
ACCESSION   NM_001107652 XM_001075253 XM_226769
VERSION     NM_001107652.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4394)
  AUTHORS   Knaevelsrud H, Soreng K, Raiborg C, Haberg K, Rasmuson F, Brech A,
            Liestol K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR and
            Simonsen A.
  TITLE     Membrane remodeling by the PX-BAR protein SNX18 promotes
            autophagosome formation
  JOURNAL   J Cell Biol 202 (2), 331-349 (2013)
   PUBMED   23878278
REFERENCE   2  (bases 1 to 4394)
  AUTHORS   Ma MP and Chircop M.
  TITLE     SNX9, SNX18 and SNX33 are required for progression through and
            completion of mitosis
  JOURNAL   J Cell Sci 125 (Pt 18), 4372-4382 (2012)
   PUBMED   22718350
REFERENCE   3  (bases 1 to 4394)
  AUTHORS   Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T and Yamamoto
            T.
  TITLE     Expression of sorting nexin 18 (SNX18) is dynamically regulated in
            developing spinal motor neurons
  JOURNAL   J Histochem Cytochem 59 (2), 202-213 (2011)
   PUBMED   21339182
REFERENCE   4  (bases 1 to 4394)
  AUTHORS   Park J, Kim Y, Lee S, Park JJ, Park ZY, Sun W, Kim H and Chang S.
  TITLE     SNX18 shares a redundant role with SNX9 and modulates endocytic
            trafficking at the plasma membrane
  JOURNAL   J Cell Sci 123 (Pt 10), 1742-1750 (2010)
   PUBMED   20427313
REFERENCE   5  (bases 1 to 4394)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 4394)
  AUTHORS   Pisitkun T, Shen RF and Knepper MA.
  TITLE     Identification and proteomic profiling of exosomes in human urine
  JOURNAL   Proc Natl Acad Sci U S A 101 (36), 13368-13373 (2004)
   PUBMED   15326289
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473955.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_226769.4, XM_001075253.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ105693.1, FQ113700.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4394
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..4394
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="sorting nexin 18"
                     /db_xref="GeneID:310097"
                     /db_xref="RGD:1310367"
     exon            1..1760
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..2014
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /note="sorting nexin associated golgi protein 1"
                     /codon_start=1
                     /product="sorting nexin-18"
                     /protein_id="NP_001101122.1"
                     /db_xref="GeneID:310097"
                     /db_xref="RGD:1310367"
                     /translation="MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGINS
                     RGDRGLFPASYVQVIRAPEPGPPADGGPGAPARYANVPPGGFEPLPAAPPAAFQPLLQ
                     PQASPGSFQSPGAGFTYGGGAPQPSPQQLYGAYQASLGSDDDWDDEWDDSSTVADEPG
                     ALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDLSLGSRGVSAPPPHQASGAKSSATVSR
                     NLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK
                     QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGR
                     FEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDE
                     MVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTG
                     FKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDP
                     VMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISF
                     ATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV"
     exon            1761..4394
                     /gene="Snx18"
                     /gene_synonym="Snag1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcagtcgct gcggtgagca gagcggatct gcacggaggc tacgagcgga acggggagca
       61 gaccgtgcgt tgccctcaag gctcgctccc ttcggcgctc aggggcgcgg gtactgaccg
      121 cggggccctc ggaccggccc gggctcgggg cgccaggctc gagaccatgg cgctacgcgc
      181 ccgggcgctc tacgacttta ggtccgagaa ccccggtgag atctccctgc gggagcacga
      241 ggtgttgagc ttgtgcagcg agcaggacat cgagggctgg cttgaaggga tcaacagccg
      301 cggcgaccgc ggcctcttcc cggcttcgta cgtgcaggtt atccgtgcgc cggagcctgg
      361 ccctccggcc gacggcggcc caggagctcc ggcccgctac gccaacgtgc cgcccggcgg
      421 cttcgagcct ctgccagccg cgccgcccgc tgccttccag ccgctgctgc agccgcaggc
      481 gtcgcccggt tccttccagt cgccgggcgc cggctttacc tacggcgggg gcgccccgca
      541 gccgtcgccc cagcagctct acggtgctta ccaggccagc ctaggcagcg acgatgactg
      601 ggacgacgag tgggacgaca gctccacagt ggcagacgag ccaggcgcgt tgggcagcgg
      661 tgcgtacccg gacctcgacg gttcgtcctc agcgggcggc ggcgcggccg gccgctaccg
      721 cttgtccaca cgctcggacc tgtcgctggg ctcccgtggc gtctcagcgc ccccgccgca
      781 tcaagcgtct ggagccaaga gctccgccac ggtgagccgc aacctcaatc ggttctccac
      841 cttcgtcaag tcgggcgggg aggcgttcgt gctgggagag gcgtcaggct tcgtgaagga
      901 tggggacaag ctgtgcgtgg tgctgggtcc ctacggcccc gagtggcagg agaaccccta
      961 ccccttccag tgcaccatcg acgatcccac caagcagacc aagttcaagg gtatgaagag
     1021 ctacatctct tacaagctgg tgcccacgca tacccaggtg cccgtgcaca ggcgctataa
     1081 gcacttcgac tggctgtatg cgcgcctggc ggagaaattc ccggtcatct cggtgcccca
     1141 tctgcccgag aagcaggcca ccgggcgctt cgaggaggac ttcatctcca agcgcaggaa
     1201 gggtctgatc tggtggatga accacatggc cagtcaccca gtgctggccc agtgcgacgt
     1261 cttccagcat ttcctgacct gccccagcag cactgatgag aaggcctgga aacagggtaa
     1321 gcggaaggct gagaaggatg agatggtggg cgccaacttc ttcctcactc tgagcacacc
     1381 acctgcggcc gccctggacc tgcaggaggt ggaaagcaag atcgatggct tcaaatgctt
     1441 caccaagaag atggatgaca gcgcgttgca gctcaaccac actgccaacg agtttgcgcg
     1501 caagcaggtg actggcttca agaaggagta tcagaaggtg ggccagtcct ttcggggcct
     1561 cagccaagcc tttgagctgg atcagcaggc cttctccgtg ggtctgaatc aggccattgc
     1621 cttcaccgga gacgcctatg atgccatcgg tgaactcttc gctgagcagc ccaggcagga
     1681 cctggaccca gtcatggacc tgttagcact gtatcagggg cacctggcca acttcccaga
     1741 catcatccat gttcagaaag gagctcttac caaagtaaag gagagtagac gacacgtgga
     1801 agaagggaag atggaggtcc aaaaggccga cggcattcaa gaccgctgta acactatttc
     1861 cttcgccacg ttggccgaga ttcatcactt ccatcaaatt agagtaagag actttaaatc
     1921 acagatgcag cattttttac aacaacaaat aatatttttc caaaaagtga cacagaagtt
     1981 ggaagaagct cttcataaat atgacagcgt ctgatggctg cacatgggac gcacatctgt
     2041 tttcagttca aggataattt ctacagcaga gcagaaactg ctttctaaga gctattgcca
     2101 actataggcg gtggtaccag gacggttttg tgttcaactg aaacccggct ggatatataa
     2161 ttacgtagga gagaagcagt taatatggtt atgtagcaga aacagtacca cactttgtaa
     2221 ctaaattata ctatgtatgc ccacactact attgtaactt ttgataatga ttatactatt
     2281 tgccttattg cttttgaagt atgggtatat tagtgtgtac tttgtagacc tcaaagccca
     2341 tgaagagtct caaagaagct ggctggatga agcctgctga ggatgccttt ttagtctcat
     2401 agatcgagat gacctaaact caacctactc tgtttacaaa ctccaactag agcagctctg
     2461 cgactttgtg ccttcagacc ggttgttttc ctttctgtcc cacctgtgtt tgagccccaa
     2521 cttctgatgg aaggagcgaa aggcgagcac tggtgacagc cgatgaaaac ctcccatttc
     2581 tgggtcagtg gtagaaccag tggccatcac tttgcacagg aagcatcgcc tggtaagatg
     2641 ctggcagtga cagaggcatg agacgctcgc tctgctgtct ctggatgtga agtctcgtag
     2701 gggaaaaggc tgtgcaccgt attcccttac agctgtttgt agcacacggc ctcgactcca
     2761 gggtcacaca gactgggcct ggggatttca gcaatgccct tagcacgtgg ggaagaatcc
     2821 aatcggggat aaagtgtaga agcagtgggt gaaaatgcac tccgtcttag tttggggaag
     2881 tgtctcctgt cttttttctt tttttctttc tttctctctt ttttagcttg aaatttcctt
     2941 ttaatgttca gctttctgtt ttgatttcaa atggatctac actgttaact gaatgatgag
     3001 actccactgt gattcactcg tttacttaat caaaaaattt cagggatgtc tgtaaatttc
     3061 agtgttgtgc acaacaagaa gtgctgttgg ttgatttaag gagggaccag aaataatttc
     3121 tactattcca gtaatgaagg aaaaaaaata ctgatttata ctgtttttaa aaactaaata
     3181 ttaataaagc cccctgtcag aaatttaacc ttaaaaatta ttttaaatat catcctatat
     3241 tattagaagg gaactacaag tgactgataa ataccaaaaa gattcacaag cagcttcatt
     3301 taaaaagcac aaagaggttc tggtgtgaaa tgcccaaatc tcaaatgttt tctgtagttc
     3361 tgagtttaca gatgtaaaag ctgtccctga aggctgcagt acctgtatct gctgtccctg
     3421 tgaactacac tcgcaccacc ccagaaaccc tggtactgat agggtagcgt gggggtacag
     3481 tctcagaggg ggtgagccac agtcacccaa cggggtcagc ttgcagaaag accaaaacag
     3541 gaaaggcgag tgggataatt acttaacagc acattcactc tctacgaagt aatcacatat
     3601 gggttgaaat ttgaagagca gattgtgatc attttgacct ctggtcaaat ccttgtactt
     3661 gagaactttg aggcggacgt ggcatcacgt ggcgttgcct ttactacagg cccgtgggac
     3721 tgttgccaaa agtcgtgttc tctgaaaaaa gcagtccctc tcgttgactg caaagtacag
     3781 ttaggtaaag aaaacccata tatatttaaa aactaatttt attccagaat tttggacgtt
     3841 ataagtttga attgtcactg aagaagcaag ctcttcctcg tttcaaatga tttggtcaca
     3901 tttatttgcc tcttcgtttt gatggtggtt tgattctttt ttctcctaat gaagttagta
     3961 aacttgtgca gtagtaacaa ggacattacc tgaggtgtct tgtatgattg tggtttagcc
     4021 agggtggaca cagcttaaat cacaaactaa agatcaaagt acaaagacgt gtgcagtcta
     4081 cgctgcctcc tcccgagata actttcctcc ctcctaacct cgtagcataa tgccaccaat
     4141 tcatggggct gtaaatgaat tctgtgggtt aatgcaccag acttaccagt gtccattttc
     4201 atccaagatt cttactctct aacgttcttg gtcctattga aacatttcag tatctaaaca
     4261 tactgcaatg ttaataccca agagaaaagc cattacgtgt atgctggtca catgatcagt
     4321 gtggtacagt tttgttactg ttgttgtttt gtttcgtcgt ttctgttttt taaataaact
     4381 atcatgccct tcaa
//
