LOCUS       NM_022289               2166 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus sorting nexin 16 (Snx16), mRNA.
ACCESSION   NM_022289
VERSION     NM_022289.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Choi,J.H., Hong,W.P., Kim,M.J., Kim,J.H., Ryu,S.H. and Suh,P.G.
  TITLE     Sorting nexin 16 regulates EGF receptor trafficking by
            phosphatidylinositol-3-phosphate interaction with the Phox domain
  JOURNAL   J Cell Sci 117 (Pt 18), 4209-4218 (2004)
   PUBMED   15292396
  REMARK    GeneRIF: SNX16 directs the sorting of EGFR to the endosomal
            compartment and thus regulates EGF-induced cell signaling.
REFERENCE   2  (bases 1 to 2166)
  AUTHORS   Hanson,B.J. and Hong,W.
  TITLE     Evidence for a role of SNX16 in regulating traffic between the
            early and later endosomal compartments
  JOURNAL   J Biol Chem 278 (36), 34617-34630 (2003)
   PUBMED   12813048
  REMARK    GeneRIF: SNX16 is a sorting nexin that may function in the
            trafficking of proteins between the early and late endosomal
            compartments
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061554.1.
            
            On Aug 31, 2012 this sequence version replaced NM_022289.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061554.1, AF305780.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132269
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2166              BC061554.1         5-2170
FEATURES             Location/Qualifiers
     source          1..2166
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..2166
                     /gene="Snx16"
                     /note="sorting nexin 16"
                     /db_xref="GeneID:64088"
                     /db_xref="RGD:620295"
     exon            1..189
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            190..663
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..1323
                     /gene="Snx16"
                     /codon_start=1
                     /product="sorting nexin-16"
                     /protein_id="NP_071625.2"
                     /db_xref="GeneID:64088"
                     /db_xref="RGD:620295"
                     /translation="MATPYVPVPMPIGNSASSFTNNRNQRSSSFGSVSTSSNSSKGQL
                     EDSSVGTCKHTNVQDQMDSASSVCGSPLIRTKFTGTDSSIEYSARPRDTEEQHPDALN
                     WEDRPSTPTILGYEVMEERAKFTVYKILVKESPEESWVVFRRYTDFSRLNDKLKEMFP
                     GFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPG
                     PFDSLEESRAFCETLEETNYHLQRELLEKQKEVESLKKLLGEKQLHIDALETRIRTLS
                     LEPGASLYVSRAEGGQILRVQSSVLQVNRDVLDEESRADHKPHFNSREAGSAIADIEV
                     AQLAYNAEDD"
     exon            664..750
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            751..899
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            900..969
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1106
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1226
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..2141
                     /gene="Snx16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttcaggcc gtcccttccc tcaggtacgc gggaacctgc ctgggtggct gtgccaaggc
       61 acagagtggc tcgtctccag cggagggtca catgaggagt ccgagtgtcc gggcaggacg
      121 ggaccagccg tagtcgaaga ggagccgcct tcctccactc ggcagcgcgg ggtcgcggag
      181 cgcaccaaga tagtgaattc ctgagaagaa aacaatgaac tgcatcttgg ttgttcttta
      241 agtatttgga cttaaaggta tacaagtttg ttgccaagac caaagaagat ggcaacccct
      301 tatgtcccag ttccgatgcc aatcggaaac tctgcttcca gctttacaaa caatagaaat
      361 cagaggagct cttcctttgg cagtgtgtca acaagctcaa actcttccaa aggccagcta
      421 gaagactcaa gtgtgggcac ttgtaagcac acgaatgtcc aggatcagat ggacagtgca
      481 tcatcagtct gcggcagtcc tctcattaga actaaattta caggtacaga ttcgtccatt
      541 gaatattctg ctagaccaag agacactgaa gaacagcacc ctgatgcact gaattgggaa
      601 gatagaccct caacacctac aattctgggt tatgaagtta tggaagagcg ggccaaattt
      661 actgtatata aaatcctagt aaaggaaagt ccagaagaaa gctgggtagt tttcagaaga
      721 tacactgact tctccaggct taatgacaaa ttaaaagaga tgtttccagg ctttcgatta
      781 gcacttcctc caaaacgctg gtttaaagat aattacaatg cagactttct agaagacaga
      841 caattaggac tacaagcgtt tcttcaaaac ttagtagctc acaaagacat cgctaactgc
      901 cttgcagtga gagaatttct ttgtctggat gatccaccag gtccatttga tagcctagaa
      961 gaaagcaggg ctttctgtga gactttagaa gagactaact accatttaca gagagaacta
     1021 cttgagaagc aaaaagaggt ggaatccctg aagaaactgc ttggggaaaa gcaacttcac
     1081 atagatgcgt tagagaccag aatcagaaca ttgtccttag aaccgggagc atcactgtat
     1141 gtgtcgagag cagaaggtgg acagatccta agggtgcagt cctctgtact tcaagtcaat
     1201 cgggatgtct tggatgaaga atctagagct gatcataagc cacacttcaa ctctagagaa
     1261 gccggaagtg caatagcaga catagaagtc gcacagttgg catataatgc tgaagatgac
     1321 taacacactg gtgactgctc cctccatttc atcattttag cagatttcag cagagtggca
     1381 aatgccaccc tcaaagactg aaacagaaga gaacaagaat gcacgtgtat aaagtttaca
     1441 taatttgttt ttttagttat tggataggaa ctgtattcac tgctgctttc gatatctttt
     1501 atccagcgtt gtatttacta cattgaaaaa aatatacagt tagaattgtt atcagagccc
     1561 atgttcttaa aaactttaca taaattatta cagtgtcttg cctgtatatt gctccaaact
     1621 actgtgttag tgtatatgtg tgtgcttgct tgtcctaaat caccacttat attaggtgaa
     1681 aattaattgc atgttagaat ctgggtaatt tctctatctc agatatgata tagatttaaa
     1741 tcagtgaaca ccacaggaaa gataaataag aatccagttt gaaatgttaa tgtctatcat
     1801 ctctagataa aagttgctta tttgaaatgt taatactatt taaaagaaga tgactttcta
     1861 gaaccaaaga taatgtgttt tgaaaagcta taattagata ggcaaagcga taaaaaagcc
     1921 ttgattcaaa tgatgattaa ttaatgtcaa gatacttact gtaagtgtcc tggtttatta
     1981 atatattata cttggatatt ttcctgcata atcttcaact cagttttcta cccataaatt
     2041 cactggggtt gcctctttca gaacactacc tctttttgct aatcaaggca tattcttttc
     2101 aaaataaatt acagttttga ggcaagtgag ttatagaaaa aaaaaaaaaa aaaaaaaaaa
     2161 aaaaaa
//
