LOCUS       NM_001399693            6245 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus sorting nexin 13 (Snx13), transcript variant 1,
            mRNA.
ACCESSION   NM_001399693 XM_006240023
VERSION     NM_001399693.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6245)
  AUTHORS   Mas,C., Norwood,S.J., Bugarcic,A., Kinna,G., Leneva,N., Kovtun,O.,
            Ghai,R., Ona Yanez,L.E., Davis,J.L., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for different phosphoinositide specificities of
            the PX domains of sorting nexins regulating G-protein signaling
  JOURNAL   J Biol Chem 289 (41), 28554-28568 (2014)
   PUBMED   25148684
REFERENCE   2  (bases 1 to 6245)
  AUTHORS   Xie,G.X. and Palmer,P.P.
  TITLE     How regulators of G protein signaling achieve selective regulation
  JOURNAL   J Mol Biol 366 (2), 349-365 (2007)
   PUBMED   17173929
  REMARK    Review article
REFERENCE   3  (bases 1 to 6245)
  AUTHORS   Zheng,B., Ma,Y.C., Ostrom,R.S., Lavoie,C., Gill,G.N., Insel,P.A.,
            Huang,X.Y. and Farquhar,M.G.
  TITLE     RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular
            trafficking
  JOURNAL   Science 294 (5548), 1939-1942 (2001)
   PUBMED   11729322
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jan 13, 2022 this sequence version replaced XM_006240023.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.17617.1,
                                           SRR26360172.109765.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               JAXUCZ010000006.1  57486684-57486903
            221-333             JAXUCZ010000006.1  57520897-57521009
            334-436             JAXUCZ010000006.1  57524797-57524899
            437-526             JAXUCZ010000006.1  57527618-57527707
            527-648             JAXUCZ010000006.1  57528659-57528780
            649-770             JAXUCZ010000006.1  57538313-57538434
            771-872             JAXUCZ010000006.1  57538519-57538620
            873-961             JAXUCZ010000006.1  57539793-57539881
            962-1045            JAXUCZ010000006.1  57545929-57546012
            1046-1184           JAXUCZ010000006.1  57548338-57548476
            1185-1273           JAXUCZ010000006.1  57548835-57548923
            1274-1373           JAXUCZ010000006.1  57550811-57550910
            1374-1567           JAXUCZ010000006.1  57552926-57553119
            1568-1672           JAXUCZ010000006.1  57554328-57554432
            1673-1805           JAXUCZ010000006.1  57554988-57555120
            1806-1843           JAXUCZ010000006.1  57558438-57558475
            1844-1913           JAXUCZ010000006.1  57560345-57560414
            1914-2053           JAXUCZ010000006.1  57565392-57565531
            2054-2161           JAXUCZ010000006.1  57569002-57569109
            2162-2272           JAXUCZ010000006.1  57570496-57570606
            2273-2434           JAXUCZ010000006.1  57574400-57574561
            2435-2506           JAXUCZ010000006.1  57575678-57575749
            2507-2652           JAXUCZ010000006.1  57580836-57580981
            2653-2721           JAXUCZ010000006.1  57581218-57581286
            2722-2834           JAXUCZ010000006.1  57583063-57583175
            2835-6245           JAXUCZ010000006.1  57586214-57589624
FEATURES             Location/Qualifiers
     source          1..6245
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q16"
     gene            1..6245
                     /gene="Snx13"
                     /note="sorting nexin 13"
                     /db_xref="GeneID:362731"
                     /db_xref="RGD:1309778"
     exon            1..220
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..3082
                     /gene="Snx13"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="sorting nexin-13 isoform 1"
                     /protein_id="NP_001386622.1"
                     /db_xref="GeneID:362731"
                     /db_xref="RGD:1309778"
                     /translation="MMLTEASLSIWGWGSLGIVLFLITFGPFVIFYLAFYILCFVGGG
                     LVVTLLYGKTNSEKYLEQCEHSFLPPTSPGVPKCLEEMKREARTIKIDRRLTGANIID
                     EPLQQVIQFSLRDYVQYWYYTLSDDETFLLEIRQTLQNALIQFATRSKEIDWQPYFTT
                     RMVDDFGTHLRVFRKAQQRVTEKDDQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSP
                     KDEEGFLRDLCEVLLYLLLPPGDFQSKIMRYFVREILARGILLPLINQLSDPDYINQY
                     VIWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQ
                     INSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYM
                     QQTGGQAHLFFWMTVEGYRVTAQQQLEVLSSRQRDGKQQTNQTKGLLRAAAVGIYEQY
                     LSEKASPRVIVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNP
                     LYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSSVTSDDSVQLHAYI
                     SDTGVCNDHGKTYALYAITVHRRSLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSIL
                     KLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLTPEMLKASPALAHCVYDFLENKAYSKG
                     KGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGVTKMSDNVGRMSERLGQDIKQS
                     FFKVPPLITKTDSDPEHCRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNI
                     KNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDALWPNGILAEAAPCRD
                     KAIRMRTRIAGKTKLFAVMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLE
                     GFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQSTQAPSLQKR"
     exon            221..333
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            334..436
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            437..526
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            527..648
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            649..770
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            771..872
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            873..961
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1045
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1184
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1273
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1373
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1567
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1672
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1805
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1843
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1844..1913
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2053
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2161
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2272
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2434
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2506
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2507..2652
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2653..2721
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2834
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..6245
                     /gene="Snx13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggacgtcg ctcttccaag atggcggcgc gtccgtcgcg agcagccggg ccggggggaa
       61 gccagcgaag ccgagtaaag ccgccgcccg ggacaggact gaagcagcag ttgccgccgt
      121 tggcggcggc ccgggcagtt tccgctgctg ctacggctgt tgccatgcgg cgaggctagg
      181 gaggacgtca ctcccccggg gtgtaatgat gttaacagag gccagtctat ccatatgggg
      241 atggggaagc cttggcattg tcctttttct aataaccttt ggaccctttg taatatttta
      301 tttggcattt tatatcctct gctttgtggg agggggttta gtggttactc ttctgtatgg
      361 gaaaactaac tcagaaaaat acctagagca gtgtgaacac tcatttcttc ctccaacatc
      421 acctggggtt cctaagtgct tagaagaaat gaaacgagaa gccaggacta ttaagattga
      481 tagaagattg acgggtgcca atataattga tgagcctctc cagcaagtta tccagttttc
      541 cttaagggat tatgtccagt actggtatta cactttaagt gatgatgaga catttcttct
      601 tgaaattaga caaactcttc aaaatgcact cattcagttt gctactaggt caaaagaaat
      661 agactggcaa ccttatttta ctacacgcat ggtagatgat tttggcactc acctacgagt
      721 attcagaaag gcccaacaga gagtaacaga gaaagatgat caagtaaaag gtacagcaga
      781 ggatctggta gaaacttttt ttgaagttga agttgaaatg gagaaggatg tttgccggga
      841 tctagtgtgt acttctccca aagatgaaga aggattccta agggatttgt gtgaggtttt
      901 attatattta ttgctacctc ctggagattt ccagagcaag atcatgcgat actttgtcag
      961 ggagatcctt gcacgaggaa ttcttcttcc attaataaat caactcagtg atcctgatta
     1021 tattaatcaa tatgtcatat ggatgatccg tgattcaaat tgcaactatg aggcctttat
     1081 gaacattatc aaattaagtg acaatattgg agagttagaa gcagtcagag ataaggcagc
     1141 agaagagcta cagtacctta gatctttaga cacagccggt gatgatatta acactatcaa
     1201 aaatcaaata aatagcttat tatttgtaaa gaaagtatgt gactcaagaa tacagcggtt
     1261 acagtcgggc aaagaaataa atactgtgaa gctagcagca aactttggga aactttgtac
     1321 agtccccttg gacagcattc ttgtagacaa tgttgcacta caatttttta tggattatat
     1381 gcagcaaact ggaggccaag cacatctctt cttctggatg acagtggaag ggtaccgggt
     1441 tacagcccag cagcagctag aggttctatc gagtcgtcag agagatggta aacaacagac
     1501 caaccaaacc aaaggtcttt taagagcagc agctgttgga atttatgaac agtatttatc
     1561 tgaaaaggca tctccaagag ttattgttga tgactattta gtagcaaaat tagcagatac
     1621 tttgaatcat gaagatccaa ctccagaaat ctttgatgac attcagagaa aggtatatga
     1681 attgatgcta cgagatgaaa gattttatcc ttcctttagg cagaatccac tctatgtgcg
     1741 aatgctagcc gagcttgaca tgttaaaaga tcccagtttc agaggatcag atgatgggga
     1801 cggagaatct tttaatgggt cgcctacagg aagcataaat ttgtctttag atgacctttc
     1861 aagtgtgacg tctgatgatt ctgtacaact tcatgcctac atttcagaca ctggcgtttg
     1921 taatgatcat ggcaagacat atgcactgta tgccatcact gtgcaccggc gcagcctcaa
     1981 cactgaggag atgtggaaaa cctatcggcg ctatagtgac ttccatgact tccacatgag
     2041 aatcactgag cagtttgaaa atctgtcaag tatattgaag cttcctggta aaaagacttt
     2101 caacaatatg gatagagatt ttttagagaa gaggaaaaag gatttaaatg cttatttgca
     2161 gttacttttg acccctgaaa tgttgaaggc gtcccctgcg ctggctcact gtgtctatga
     2221 tttccttgag aacaaagcct acagtaaagg gaagggcgat tttgctcgaa agatggacac
     2281 ttttgtaaat ccccttcgta actctatgag gaatgtttca aatgcagtca agtcccttcc
     2341 tgacagcttg gcagaaggag tgacaaaaat gtcggacaac gtgggcagaa tgtcggagag
     2401 attagggcaa gacataaagc agtcattttt taaggtacct cctttaatta caaagactga
     2461 ttcggatcct gagcattgtc gagtctcagc tcagcttgat gataatgtgg atgacaatat
     2521 tccacttagg gtaatgctgc ttctaatgga tgaggtattt gacttaaaag agagaaacca
     2581 gtggttgaga aggaatatca agaatttact ccaacaactt attagagcta catatggtga
     2641 tactattaac agaaaaatag ttgaccatgt tgactggatg acctcaccgg aacaagtggc
     2701 tgactcggtg aagcgtttca gagacgcact ttggcccaat ggcattttag cagaggctgc
     2761 tccgtgcagg gataaagcca ttaggatgag aacaagaatt gcaggaaaaa caaagttatt
     2821 tgcagttatg ccagatgaac tgaagcacat tattggcgct gagacaacac ggaaaggtat
     2881 tcttcgtgtt tttgaaatgt ttcagcacaa ccagttaaac aggaggatgg tgtatgtctt
     2941 cttagaaggc tttttagaaa ccttatttcc acagtataaa tttcgtgaac ttttcaacaa
     3001 acttcattca aggtcaaagc aaatgcagaa atataaacaa aaacttcaaa gtactcaagc
     3061 gccttcttta caaaaaaggt gacactccaa cctgtgaagg tggtgttcat tttgtccagg
     3121 actaatggtg tggacagatc ttctgggatg taactcacat actgttgcgt ctacaccagt
     3181 ctttccgtgt ctcaacacag attcctagta cacccataga ctggtcttct cattctcctc
     3241 tgtaatccag ccactaccaa gagagattcc tgtgtcttac atgatttggt gcataatttg
     3301 caacattgag aggatactgc cccatctcgt tcaagaatgg agttggcctc ttccgttcca
     3361 aactaatcag cattctctcc tagtgccaga gtgccagagt gtatgtgtga gagctgaggg
     3421 aagcacgcca ccgtgggtca taggtaactt cactaactag gttagtagct gcagagcgca
     3481 gtgcacaatt ggagagattg gtttcattca aggatcttgt gggtcgtcag cattttgcta
     3541 tcatgtgggt tagcaggtaa gattgatctt tagaacaatt gttcaattgt ttcaacgcgg
     3601 cctgggcaaa gtgagagaaa gaaggccctt agtgtaggaa acagcccttc ccaaattgca
     3661 gtcttgtgta aagtaaagca ctataaaata aaaccaatca aaaccacaac ttgattgggt
     3721 ttattattca ttgatagagt tttcattgac tgtctttgtc catgtgcttt ggggctcggc
     3781 ttcgctctta cggcgctcag ctctccaccc ttcttttggc atctgggcag aagcatgtgg
     3841 tagctctctt aggagttcag gttttaatct tttaacagat tactgattat atagaaggga
     3901 aattatttat tgtaagaact gccaaataca ttgtccttct aaaaattgga aattaaaaca
     3961 gtactctatt gaaagttacc atatgataac tttaaatcgt atgatctaga catgccttag
     4021 gtaactacca atatagcaaa tcaaaggatt aatgagctta tagtcctatg taaacataca
     4081 aatgcctaat tctactatgt gtacatatat gaaaataaat aatgaaaaca gaactgtact
     4141 atttttaaaa atatgctttt atttatattt cgcataatgt aaaattctaa ataaagctag
     4201 tacacaaaac cctttggtgt atacatttaa cgccctaata ttttatatca gtgaaacaaa
     4261 taccttttcg aggtgtgaag cctttgcatt tcttagtgtt ctccattttg tccattagga
     4321 agtcttcata tcccatatat gcaggatttc tgtactttta aatacttcca atgactaggg
     4381 gtttggatat atcatctctt tttgttttaa aaatatttaa cactaaaacc ttaaaatagt
     4441 gaaactactt ttcagaccac tgagccagta ccctgctatt taaagaatgt gtgggtgctc
     4501 actgtaaagg gacagagtat tgatgatcca gttacttggg agctttaaga ttggaatagg
     4561 atttgctctt gctgtcgtca ctcagatcct tcttatgcag tgcagcctgg taatgcgagg
     4621 gaagcattcc tgtgaagctt taggagctgt cagtgctgag tgcatatgtt tagtgtgcac
     4681 atgttcagca tgtgttgcat gtctttcaga atcacgtaag taaaacccct ttttgaaact
     4741 tgcaagtgag aaaagattct gtctctctgg cagaagacat gtttcctgta ctcatcatat
     4801 gctcctgccc ctgccctgcc ggcccttcct cggccccagg cttaaaatta ggaagcatca
     4861 atcagcatgg tcacaagtgc aataatttca taaatagcct ccaatttcaa ttatattttt
     4921 acgtgaatac attaaagtgt atacagaagg attcatgatg caagagccta gtgtgtacat
     4981 gtgaaaagtg tttctatata aagaaaactg tcaaccaggg gaaaaagagg tcatgtaaaa
     5041 tgcagattct tctaatagcc ctgcaagaca actgcaaaca caccaaacag agtaaagcaa
     5101 agagaaaact atttgagtaa atagtttttt aaggtaattt ttattgaaaa gcatttgtat
     5161 atttcaggag cagaaatgtc gaatggccac gtgtctgtgt gcacgtctgt gttttacaac
     5221 ggagactgag gtcatgctat agctgcagat agcctaggct tggtctagcc atgtagagta
     5281 tttaacccat aagcaaagta cagtgttctg cgtttcacaa agttattata ttttgtgtat
     5341 ttgttgcaca tatgaacata aacacaaaga ggctttatgt cttctgctga atgcttttaa
     5401 gtcagtggtg cctttaggca agaaccatcg aaattaatca ttcttttggg ttttctgata
     5461 ttttttcagg taccgtaaaa ctgcaaagaa actatcacag cttactctcc taaagtccga
     5521 ttgtctgact taaatgtagc acttagatga gtatttcctg taattccagt gttccacgta
     5581 gttgctggaa cagttgtgcc attgaccagt ggatgcactt tgttagcctt aatttaaaac
     5641 aaaaaaaatt ttcttgaata tatcagtttg atcactataa gtttgctgca ggtgttttgg
     5701 ggaaaaaaca gttaagtgca atgaaagtgt accattttta aaaaaataaa ttaagaacaa
     5761 cataaatttc acaatctgca gttttaattt tgtgcaatat tttcatttaa tgcatgttta
     5821 tttgagtaac tgtaaaataa ctacattttt aatgtttgag atctaattta actgtcttct
     5881 tagcccaaca acttcattcc gttgttgccg caccttaatt aaggacttgt ttaaaagtct
     5941 ttttgtcact ccttgtaaaa ttcttttctt agtagaaagt ttcgcttatg ggagcctggc
     6001 tcctgtatta taagggaaaa ctaaagagca cattttagga ttttaattgt taaaaaatta
     6061 ccttgtgcat atcattgtac ataagtgtca attgtgccta accgctctat caatgctctc
     6121 cttctttaac caaggggaaa gaatcagaat gtcagttatt tttattaact acagaattaa
     6181 aatttttatt tggtttgtgt tatgttctgt ctgttagaaa atactaataa agtattaaca
     6241 aacaa
//
