LOCUS       NM_001130542            2502 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus syntrophin, beta 1 (Sntb1), mRNA.
ACCESSION   NM_001130542 XM_001067142 XM_235312
VERSION     NM_001130542.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2502)
  AUTHORS   Lubelwana Hafver,T., Wanichawan,P., Manfra,O., de Souza,G.A.,
            Lunde,M., Martinsen,M., Louch,W.E., Sejersted,O.M. and Carlson,C.R.
  TITLE     Mapping the in vitro interactome of cardiac sodium (Na+)-calcium
            (Ca2+) exchanger 1 (NCX1)
  JOURNAL   Proteomics 17 (17-18) (2017)
   PUBMED   28755400
REFERENCE   2  (bases 1 to 2502)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   3  (bases 1 to 2502)
  AUTHORS   Lyssand,J.S., DeFino,M.C., Tang,X.B., Hertz,A.L., Feller,D.B.,
            Wacker,J.L., Adams,M.E. and Hague,C.
  TITLE     Blood pressure is regulated by an alpha1D-adrenergic
            receptor/dystrophin signalosome
  JOURNAL   J Biol Chem 283 (27), 18792-18800 (2008)
   PUBMED   18468998
REFERENCE   4  (bases 1 to 2502)
  AUTHORS   Leonoudakis,D., Conti,L.R., Anderson,S., Radeke,C.M., McGuire,L.M.,
            Adams,M.E., Froehner,S.C., Yates,J.R. 3rd and Vandenberg,C.A.
  TITLE     Protein trafficking and anchoring complexes revealed by proteomic
            analysis of inward rectifier potassium channel (Kir2.x)-associated
            proteins
  JOURNAL   J Biol Chem 279 (21), 22331-22346 (2004)
   PUBMED   15024025
REFERENCE   5  (bases 1 to 2502)
  AUTHORS   Adams,M.E., Kramarcy,N., Krall,S.P., Rossi,S.G., Rotundo,R.L.,
            Sealock,R. and Froehner,S.C.
  TITLE     Absence of alpha-syntrophin leads to structurally aberrant
            neuromuscular synapses deficient in utrophin
  JOURNAL   J Cell Biol 150 (6), 1385-1398 (2000)
   PUBMED   10995443
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 28, 2008 this sequence version replaced
            XM_235312.4, XM_001067142.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5756307, SAMEA5760383
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2502
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q32"
     gene            1..2502
                     /gene="Sntb1"
                     /note="syntrophin, beta 1"
                     /db_xref="GeneID:299940"
                     /db_xref="RGD:1307728"
     exon            1..969
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             396..2015
                     /gene="Sntb1"
                     /note="syntrophin, basic 1"
                     /codon_start=1
                     /product="beta-1-syntrophin"
                     /protein_id="NP_001124014.1"
                     /db_xref="GeneID:299940"
                     /db_xref="RGD:1307728"
                     /translation="MAVAAAAAAVAAPAGGGGARAQRSGLLEVLVRDRWHKVLVNLSE
                     DALVLSCEEGATAYNGIGTTTNGSFCRGSGTGHPGTGVPQAPDSPAGVRTAFTDLPEQ
                     VPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDA
                     ILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPP
                     ESPRLGSGSADPLSSQPFSFHRDRKSIPLKMCYVTRSMTLADPENRQLEIHSPDAKHT
                     VVLRSKDSATAQAWFSAIHSNVGDLLVRVVADIREQLGKTGIAGSREIRHLGWLAEKV
                     PGESEKQWKPALVVLTEKDLLIYDSMPRRKEAWLSPVHSYPLLATRLVHSGPGKGSPQ
                     AAMDLSFATRTGTKQGIETHLFRAEISRDLSHWTRSIVQGCHNSAELTAEITTACTYR
                     NQECRLTIHYDNGFSISTEPQDGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKEGE
                     IQLDLHSCPKPIVFIIHSFLSAKITRLGLVA"
     exon            970..1186
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1394
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1395..1534
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1731
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1922
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..2502
                     /gene="Sntb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagtggcga acaggtgagc ggctggggct ccgggtcccc gcccctgcct cctcctaccg
       61 gttctcaata gcacttggcc gctccgcggc tcctctcggt ttggggtttt gcaactggca
      121 gctggctttt ttccctcctc ccctgtcgag ggctctcctt cttcttttag gttgctccac
      181 cccgcccagg atcaggcgag gggggaacaa gctccgccgc tgccaactgg cgcccagtgc
      241 agccgcgaac acggggagtg gagtccggga tccaagagcg cgctgcgggg catctgcttc
      301 ttccacgccc cagctacccc gagtcctctc accctcaccc cttctccact tttcccccgt
      361 ttgcaatcac atggcatttt aagaatgctg gaaagatggc ggtagcggca gcggcagcgg
      421 ctgtggctgc gccggctggc ggtggaggcg cccgggcgca gcggagcgga ctgttggaag
      481 ttttggtgcg ggatcgctgg cataaagttc tggtgaactt gagcgaggac gccctggtgt
      541 tgagctgcga ggagggcgct acggcgtaca acggcatagg gactaccacc aatggttcgt
      601 tctgcagggg ctccgggacc gggcacccgg gcactggtgt gcctcaagcc ccggactctc
      661 ctgccggggt ccgcaccgcc ttcaccgacc tgccagagca ggtgcctgag tccatctcaa
      721 accagaagag gggcgtgaag gtcctgaagc aggagctggg cgggctgggc attagcatca
      781 aagggggcaa ggaaaacaag atgcccatac tcatcagcaa gatcttcaag gggctggcag
      841 ccgatcagac ccaagccctg tacgtgggcg atgccatcct gtcagtgaat ggagcagacc
      901 tgcgggacgc cacccacgac gaggcagtac aggcgctgaa gcgcgcaggc aaggaagtgc
      961 tgctggaagt gaagtacatg agagaagcca caccttacgt gaagaaagga tcccctgtgt
     1021 ctgagattgg atgggaaaca cctccacctg agtccccaag attagggagt ggctctgcag
     1081 atcctctgtc atcccagccc ttctccttcc atagagaccg gaaaagcatc cccctcaaga
     1141 tgtgttatgt cacccggagc atgactttgg ctgaccctga aaacaggcag cttgaaattc
     1201 actcgccaga tgctaagcac acagtggtcc tgaggagtaa ggactctgcc actgcccaag
     1261 cctggttcag tgctatccat tccaacgttg gtgacttgct ggtccgtgtg gttgctgaca
     1321 tcagggagca gctggggaag acaggtattg ctggcagtcg tgagatcagg catcttggct
     1381 ggcttgcaga aaaggtacct ggagagagtg agaaacagtg gaaaccagcc ctggttgttc
     1441 tgactgagaa ggatcttcta atctatgaca gcatgccgcg gaggaaagag gcctggctta
     1501 gcccagtaca ttcgtaccca cttcttgcca ccaggttggt ccattcgggc ccagggaaag
     1561 gatcacctca ggctgctatg gacctgtcct ttgcaactcg aactggtacc aagcaaggaa
     1621 ttgaaacaca tctcttcagg gcagagatca gcagggacct ctcccactgg acaaggagca
     1681 tagtacaggg gtgccacaat tcagcagagc tcactgctga aatcaccacc gcctgcacct
     1741 acagaaacca ggaatgccgc ttgaccatac attacgacaa tggattttct atttccactg
     1801 agcctcagga tggtgccttt cccaagacaa tcatacagtc cccttatgag aagctcaaaa
     1861 tgtcttcgga tgatggaatc aggatgctct atttagactt tggaggcaaa gaaggagaga
     1921 ttcaactgga ccttcactcc tgccccaagc ccatcgtttt catcatccat tcctttctgt
     1981 ctgctaagat cacacgactg ggcttggtgg cctgaacaga ggggcgactt gccttaggaa
     2041 aggaagcctg ccgtgcctca ggactgtgac atcgggcagt gcaccagatg tagcatgcac
     2101 agccagctgc aggtttcagg agtcacatgt accatcatcc caggctcctc catcggtttc
     2161 agaaactcca agggacaccc taaagaaaac accacagggg ttttatcaga ataaaatttc
     2221 atagaataga acaaagaggt gagggtgggt gaatatgcag agcatatctc taaaattatg
     2281 acaaccaagg acacagccat tacagcagca caggaagatc ttaatcagtc cagtctctag
     2341 gcaactggtt cgcccaggta agccagagcc aagccgatga gaaacaacta gctacacctt
     2401 ttcctctgcc cctagtaaca gcctcttgct ttcctgtgat tatttcccga ttcaagttga
     2461 gctaactatc cttggtagga acaacaacaa tgcacacctt tt
//
