LOCUS       NM_031117               1468 bp    mRNA    linear   ROD 19-AUG-2024
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein polypeptide N
            (Snrpn), mRNA.
ACCESSION   NM_031117
VERSION     NM_031117.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1468)
  AUTHORS   Timalsina,B., Choi,H.J. and Moon,I.S.
  TITLE     N-Acetylglucosamine Kinase-Small Nuclear Ribonucleoprotein
            Polypeptide N Interaction Promotes Axodendritic Branching in
            Neurons via Dynein-Mediated Microtubule Transport
  JOURNAL   Int J Mol Sci 24 (14), 11672 (2023)
   PUBMED   37511433
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1468)
  AUTHORS   Zhang,Q., Zhang,F., Gao,H.H. and Zhang,J.M.
  TITLE     Effects of varicocele on DNA methylation pattern of H19 and Snrpn
            gene in spermatozoa and behavioural characteristics of adult rat
            offspring
  JOURNAL   Andrologia 49 (1) (2017)
   PUBMED   27071665
  REMARK    GeneRIF: Varicocele does not alter the methylation profiles of H19
            and Snrpn gene, but exerts depressant-like effect on the adult rat
            offspring.
REFERENCE   3  (bases 1 to 1468)
  AUTHORS   Meng,F., Xu,L., Huang,S., Liu,Y., Hou,Y., Wang,K., Jiang,X. and
            Li,G.
  TITLE     Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes
            osteogenic differentiation of bone marrow mesenchymal stem cells by
            regulating Runx2
  JOURNAL   Cell Tissue Res 366 (1), 155-162 (2016)
   PUBMED   27184949
  REMARK    GeneRIF: Sm51 plays an important role in regulating osteogenic
            differentiation of mesenchymal stem cells through increasing Runx2
            expression
REFERENCE   4  (bases 1 to 1468)
  AUTHORS   Ishikawa,T., Kibe,T. and Wada,Y.
  TITLE     Deletion of small nuclear ribonucleoprotein polypeptide N (SNRPN)
            in Prader-Willi syndrome detected by fluorescence in situ
            hybridization: two sibs with the typical phenotype without a
            cytogenetic deletion in chromosome 15q
  JOURNAL   Am J Med Genet 62 (4), 350-352 (1996)
   PUBMED   8723064
REFERENCE   5  (bases 1 to 1468)
  AUTHORS   Huntriss,J.D., Latchman,D.S. and Williams,D.G.
  TITLE     The snRNP core protein SmB and tissue-specific SmN protein are
            differentially distributed between snRNP particles
  JOURNAL   Nucleic Acids Res 21 (17), 4047-4053 (1993)
   PUBMED   8371979
REFERENCE   6  (bases 1 to 1468)
  AUTHORS   Schmauss,C. and Lerner,M.R.
  TITLE     The closely related small nuclear ribonucleoprotein polypeptides N
            and B/B' are distinguishable by antibodies as well as by
            differences in their mRNAs and gene structures
  JOURNAL   J Biol Chem 265 (18), 10733-10739 (1990)
   PUBMED   1693924
REFERENCE   7  (bases 1 to 1468)
  AUTHORS   Esposito,F., Ammendola,R., Duilio,A., Costanzo,F., Giordano,M.,
            Zambrano,N., D'Agostino,P., Russo,T. and Cimino,F.
  TITLE     Isolation of cDNA fragments hybridizing to rat brain-specific mRNAs
  JOURNAL   Dev Neurosci 12 (6), 373-381 (1990)
   PUBMED   1981744
REFERENCE   8  (bases 1 to 1468)
  AUTHORS   Li,S., Klein,E.S., Russo,A.F., Simmons,D.M. and Rosenfeld,M.G.
  TITLE     Isolation of cDNA clones encoding small nuclear
            ribonucleoparticle-associated proteins with different tissue
            specificities
  JOURNAL   Proc Natl Acad Sci U S A 86 (24), 9778-9782 (1989)
   PUBMED   2532363
REFERENCE   9  (bases 1 to 1468)
  AUTHORS   McAllister,G., Roby-Shemkovitz,A., Amara,S.G. and Lerner,M.R.
  TITLE     cDNA sequence of the rat U snRNP-associated protein N: description
            of a potential Sm epitope
  JOURNAL   EMBO J 8 (4), 1177-1181 (1989)
   PUBMED   2526016
REFERENCE   10 (bases 1 to 1468)
  AUTHORS   Schmauss,C., McAllister,G., Ohosone,Y., Hardin,J.A. and Lerner,M.R.
  TITLE     A comparison of snRNP-associated Sm-autoantigens: human N, rat N
            and human B/B'
  JOURNAL   Nucleic Acids Res 17 (4), 1733-1743 (1989)
   PUBMED   2522186
  REMARK    Erratum:[Nucleic Acids Res 1989 Aug 25;17(16):6777]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1, FM122235.1 and BC087671.1.
            
            On Jul 27, 2012 this sequence version replaced NM_031117.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M29293.1, SRR26360190.1463453.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-210               JAXUCZ010000001.1  120338710-120338919 c
            211-239             JAXUCZ010000001.1  120333716-120333744 c
            240-734             FM122235.1         36-530
            735-1468            BC087671.1         139-872
FEATURES             Location/Qualifiers
     source          1..1468
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1468
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /note="small nuclear ribonucleoprotein polypeptide N"
                     /db_xref="GeneID:81781"
                     /db_xref="RGD:621306"
     exon            1..210
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            211..306
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            307..455
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            456..599
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     CDS             597..1319
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /note="FE294 psi pseudogene; FE294 gene for
                     snRNP-associated polypeptide N; smN; sm-D; sm-N; snRNP-N;
                     sm protein N; sm protein D; small nuclear
                     ribonucleoparticle-associated protein (snRNP) mRNA, clone
                     Sm51; small nuclear ribonucleoprotein N"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein-associated
                     protein N"
                     /protein_id="NP_112379.1"
                     /db_xref="GeneID:81781"
                     /db_xref="RGD:621306"
                     /translation="MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCD
                     CDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAG
                     GPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATAS
                     IAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPP
                     GMRPPPPGIRGPPPPGMRPPRP"
     exon            600..751
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            752..863
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1016
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1155
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1281
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1445
                     /gene="Snrpn"
                     /gene_synonym="FE 294; FE 294 psi; FE294; FE294 psi"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgtctgacc gactccttgg gtatattagt gcggcatctg cgtgtaacac gttgccttta
       61 ttatggtggt ctgaggttgt tgattgtgaa atccaggatg taggagctat gttgccgcag
      121 cctctgggct ccgggatccg agagctcttt tgtatcggcc ggtggaatct ttggatgttc
      181 gagctgtatt gccgcgacct gtagattcag ggatcgttta cacttgagaa gaactactga
      241 acagcacgtg ccagagattg aggtccaggt caaacgtaga aggacagcct cactgagcaa
      301 ccaagagtgt cacttgtacc caaggcgttc tcagcaacag caaattcctg tggtggattt
      361 ccaggcagaa ctgagacagg cgttcttagc tgagacacca agaggtggtt aaagcagtat
      421 tggaacttca aggtggtgga agtcaacaaa aacaggacct atccactgat tgtgaaactt
      481 tggtcaagct tacactgtgt taatagcctg catcaaacct ttatttattg cccttctcca
      541 agtattaagg atcttgaaat tttagtgttg acaactgcta ttgtggaaca gcaatcatga
      601 ctgtgggtaa gagtagcaag atgctccagc atattgacta tagaatgaga tgtatcctgc
      661 aagatggaag aatcttcatt ggcaccttta aggcttttga caagcatatg aatttgatcc
      721 tctgtgattg tgatgagttc aggaagatca agccaaagaa tgcaaaacag ccagaacgtg
      781 aagaaaaacg ggttttgggt ctggtcttgc tacgtggaga gaacttggtt tccatgacag
      841 tggagggtcc acctcctaaa gatactggca ttgctcgtgt gccacttgct ggtgctgcag
      901 gtggccctgg tgttggaaga gcagctggca gaggagtacc agcaggtgta cctattcccc
      961 aagctcctgc tggattagca ggccctgtcc gaggagttgg aggcccatcc cagcaggtca
     1021 tgaccccaca gggaagaggc actgttgcag ctgctgctgt tgctgctact gctagcattg
     1081 caggagcccc aacccagtac ccgccaggac ggggaactcc acctccacct gtaggcagag
     1141 caaccccacc tccaggcatt atggctcctc cacctggaat gagaccaccc atgggcccac
     1201 caattggact tccccctgct cgagggacac ctataggcat gccccctcca ggaatgagac
     1261 cccctcctcc aggaattaga ggcccacctc ccccaggaat gcgtccacca agaccctaag
     1321 atacagttga taaatctcag cccttctctt tccctacaat gcttcttgtg aaattgtgtc
     1381 gcctgcaagc ttttgacccc tcttactgca ttaactatag ataataaata catagcgcaa
     1441 ttgaaaaaaa aaaaaaaaaa aaaaaaaa
//
