LOCUS       NM_001126091             849 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein polypeptide F
            (Snrpf), mRNA.
ACCESSION   NM_001126091 XM_001058626
VERSION     NM_001126091.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 849)
  AUTHORS   Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will
            CL, Urlaub H, Kastner B, Luhrmann R and Stark H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 849)
  AUTHORS   Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K,
            Urlaub H, Kastner B, Stark H and Luhrmann R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 849)
  AUTHORS   Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H,
            Luhrmann R and Stark H.
  TITLE     Molecular architecture of the human U4/U6.U5 tri-snRNP
  JOURNAL   Science 351 (6280), 1416-1420 (2016)
   PUBMED   26912367
REFERENCE   4  (bases 1 to 849)
  AUTHORS   Kondo Y, Oubridge C, van Roon AM and Nagai K.
  TITLE     Crystal structure of human U1 snRNP, a small nuclear
            ribonucleoprotein particle, reveals the mechanism of 5' splice site
            recognition
  JOURNAL   Elife 4, e04986 (2015)
   PUBMED   25555158
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 849)
  AUTHORS   Lin SJ, Chang KP, Hsu CW, Chi LM, Chien KY, Liang Y, Tsai MH, Lin
            YT and Yu JS.
  TITLE     Low-molecular-mass secretome profiling identifies C-C motif
            chemokine 5 as a potential plasma biomarker and therapeutic target
            for nasopharyngeal carcinoma
  JOURNAL   J Proteomics 94, 186-201 (2013)
   PUBMED   24080422
REFERENCE   6  (bases 1 to 849)
  AUTHORS   Chen YI, Moore RE, Ge HY, Young MK, Lee TD and Stevens SW.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   7  (bases 1 to 849)
  AUTHORS   Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S,
            Tuschl T and Luhrmann R.
  TITLE     The human 18S U11/U12 snRNP contains a set of novel proteins not
            found in the U2-dependent spliceosome
  JOURNAL   RNA 10 (6), 929-941 (2004)
   PUBMED   15146077
REFERENCE   8  (bases 1 to 849)
  AUTHORS   Jurica MS, Licklider LJ, Gygi SR, Grigorieff N and Moore MJ.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   9  (bases 1 to 849)
  AUTHORS   Pillai RS, Will CL, Luhrmann R, Schumperli D and Muller B.
  TITLE     Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain
            Lsm10, a new 14 kDa Sm D1-like protein
  JOURNAL   EMBO J 20 (19), 5470-5479 (2001)
   PUBMED   11574479
REFERENCE   10 (bases 1 to 849)
  AUTHORS   Hermann H, Fabrizio P, Raker VA, Foulaki K, Hornig H, Brahms H and
            Luhrmann R.
  TITLE     snRNP Sm proteins share two evolutionarily conserved sequence
            motifs which are involved in Sm protein-protein interactions
  JOURNAL   EMBO J 14 (9), 2076-2088 (1995)
   PUBMED   7744013
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On Apr 30, 2008 this sequence version replaced XM_001058626.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214256.1, AA899316.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..849
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..849
                     /gene="Snrpf"
                     /note="small nuclear ribonucleoprotein polypeptide F"
                     /db_xref="GeneID:680737"
                     /db_xref="RGD:1588229"
     exon            1..175
                     /gene="Snrpf"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..433
                     /gene="Snrpf"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein F"
                     /protein_id="NP_001119563.1"
                     /db_xref="GeneID:680737"
                     /db_xref="RGD:1588229"
                     /translation="MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQL
                     ANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE"
     exon            176..301
                     /gene="Snrpf"
                     /inference="alignment:Splign:2.1.0"
     exon            302..366
                     /gene="Snrpf"
                     /inference="alignment:Splign:2.1.0"
     exon            367..849
                     /gene="Snrpf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcatcgaag cctagacaac gaggcgagag gtgaaaggtt acgcctcctt ttggcggcca
       61 tttcttttag cgcccgtcct ttcggtggtg tagcggcagc tgctccagtc acgaggggcg
      121 ggcagcggcg gggtcggcgg ctactggggt gcagcgctcg cgggtgttcg cgatgagttt
      181 acccctcaat cccaagcctt ttctcaatgg actgacagga aagccagtga tggtgaaact
      241 taagtggggc atggagtaca agggctacct ggtctccgtt gatggctaca tgaacatgca
      301 gcttgcaaat acagaagaat acatagatgg ggcattgtct ggacatctgg gtgaagttct
      361 aataaggtgt aataatgtcc tctacatcag aggtgtcgaa gaggaggagg aagatgggga
      421 gatgagagaa tagcatcttg gaattttttt ttttatatat atgtatttct atacaataaa
      481 gattggggtt ttttttcaat ttgacttgtg gactatttat atacagacat aagcaaagtg
      541 caaatgctga aacaatggat gaacgatttc ttagaactaa tgtttgaaaa gctacccggt
      601 atcattccag gggactcttt ttgtaacccc accactggct ggcttgtgtg tttatttctg
      661 taaaggatgg ctctatgctt cataattttt cttaaggtga gtttcagccc ttgtaattat
      721 attaactgag acctcttcaa agcaactgtg ttgtttaacg tttccaaacc acccttaaca
      781 tgtataaagt taaatatttt cttagtatta atatatattt tattaataaa ttatgttatt
      841 tctatattg
//
