LOCUS       NM_001399538             666 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein D3 polypeptide
            (Snrpd3), mRNA.
ACCESSION   NM_001399538 XM_003751948
VERSION     NM_001399538.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Bertram,K., Agafonov,D.E., Dybkov,O., Haselbach,D., Leelaram,M.N.,
            Will,C.L., Urlaub,H., Kastner,B., Luhrmann,R. and Stark,H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 666)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 666)
  AUTHORS   Agafonov,D.E., Kastner,B., Dybkov,O., Hofele,R.V., Liu,W.T.,
            Urlaub,H., Luhrmann,R. and Stark,H.
  TITLE     Molecular architecture of the human U4/U6.U5 tri-snRNP
  JOURNAL   Science 351 (6280), 1416-1420 (2016)
   PUBMED   26912367
REFERENCE   4  (bases 1 to 666)
  AUTHORS   Kondo,Y., Oubridge,C., van Roon,A.M. and Nagai,K.
  TITLE     Crystal structure of human U1 snRNP, a small nuclear
            ribonucleoprotein particle, reveals the mechanism of 5' splice site
            recognition
  JOURNAL   Elife 4, e04986 (2015)
   PUBMED   25555158
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 666)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 666)
  AUTHORS   Novakova,Z., Man,P., Novak,P., Hozak,P. and Hodny,Z.
  TITLE     Separation of nuclear protein complexes by blue native
            polyacrylamide gel electrophoresis
  JOURNAL   Electrophoresis 27 (7), 1277-1287 (2006)
   PUBMED   16502463
REFERENCE   7  (bases 1 to 666)
  AUTHORS   Miranda,T.B., Khusial,P., Cook,J.R., Lee,J.H., Gunderson,S.I.,
            Pestka,S., Zieve,G.W. and Clarke,S.
  TITLE     Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically
            dimethylated at arginine residues in the nucleus
  JOURNAL   Biochem Biophys Res Commun 323 (2), 382-387 (2004)
   PUBMED   15369763
REFERENCE   8  (bases 1 to 666)
  AUTHORS   Will,C.L., Schneider,C., Hossbach,M., Urlaub,H., Rauhut,R.,
            Elbashir,S., Tuschl,T. and Luhrmann,R.
  TITLE     The human 18S U11/U12 snRNP contains a set of novel proteins not
            found in the U2-dependent spliceosome
  JOURNAL   RNA 10 (6), 929-941 (2004)
   PUBMED   15146077
REFERENCE   9  (bases 1 to 666)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   10 (bases 1 to 666)
  AUTHORS   Pillai,R.S., Will,C.L., Luhrmann,R., Schumperli,D. and Muller,B.
  TITLE     Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain
            Lsm10, a new 14 kDa Sm D1-like protein
  JOURNAL   EMBO J 20 (19), 5470-5479 (2001)
   PUBMED   11574479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Jan 10, 2022 this sequence version replaced XM_003751948.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK842793.1, BE109044.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               JAXUCZ010000020.1  13144806-13144920   c
            116-257             JAXUCZ010000020.1  13143386-13143527   c
            258-450             JAXUCZ010000020.1  13132310-13132502   c
            451-666             JAXUCZ010000020.1  13129557-13129772   c
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..666
                     /gene="Snrpd3"
                     /note="small nuclear ribonucleoprotein D3 polypeptide"
                     /db_xref="GeneID:687711"
                     /db_xref="RGD:1597573"
     exon            1..115
                     /gene="Snrpd3"
                     /inference="alignment:Splign:2.1.0"
     exon            116..257
                     /gene="Snrpd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..512
                     /gene="Snrpd3"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein Sm D3"
                     /protein_id="NP_001386467.1"
                     /db_xref="GeneID:687711"
                     /db_xref="RGD:1597573"
                     /translation="MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMS
                     NITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAI
                     LKAQVAARGRGRGMGRGNIFQKRR"
     exon            258..450
                     /gene="Snrpd3"
                     /inference="alignment:Splign:2.1.0"
     exon            451..666
                     /gene="Snrpd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attctgggag cgcgtggtgt gagtgatact cgggcccgtc gtttcctcgc ctcaagcctt
       61 cgccttctaa cgtttgtgcc gggaccgaaa aaaaaaaaaa gcctgcagtt agttggaaga
      121 gtcctgccaa gatgtctatc ggtgtgccaa ttaaagtcct gcacgaagcg gaaggccaca
      181 tagtgacatg tgagaccaac actggtgaag tgtatcgggg gaagctcatt gaggcagagg
      241 acaacatgaa ctgccagatg tccaacatca cagtcacata cagagacggc cgagtggcac
      301 agctggaaca ggtgtacata cgtggcagca agatccggtt tctgattttg cctgacatgc
      361 tgaaaaatgc acccatgtta aagagcatga aaaataaaaa ccaaggctca ggggctggcc
      421 gaggaaaagc tgctatcctg aaggcccaag tggctgcaag aggaagagga cgtggaatgg
      481 ggcgtggaaa cattttccag aagcgaagat agtgctctcc attgaagaga actttgtcct
      541 gtcttctctt aggtttttgg gctttggggg tggggcgggg ggttatatgt gcatatgtcc
      601 tgggttttaa tatttctctt tgtattggag aaactgttaa gctaaataaa atttggtttt
      661 gtgttt
//
