LOCUS       NM_001109399             604 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein D2 polypeptide
            (Snrpd2), mRNA.
ACCESSION   NM_001109399 XM_001056581
VERSION     NM_001109399.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Bertram,K., Agafonov,D.E., Dybkov,O., Haselbach,D., Leelaram,M.N.,
            Will,C.L., Urlaub,H., Kastner,B., Luhrmann,R. and Stark,H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 604)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 604)
  AUTHORS   Agafonov,D.E., Kastner,B., Dybkov,O., Hofele,R.V., Liu,W.T.,
            Urlaub,H., Luhrmann,R. and Stark,H.
  TITLE     Molecular architecture of the human U4/U6.U5 tri-snRNP
  JOURNAL   Science 351 (6280), 1416-1420 (2016)
   PUBMED   26912367
REFERENCE   4  (bases 1 to 604)
  AUTHORS   Kondo,Y., Oubridge,C., van Roon,A.M. and Nagai,K.
  TITLE     Crystal structure of human U1 snRNP, a small nuclear
            ribonucleoprotein particle, reveals the mechanism of 5' splice site
            recognition
  JOURNAL   Elife 4, e04986 (2015)
   PUBMED   25555158
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 604)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 604)
  AUTHORS   Chen,Y.I., Moore,R.E., Ge,H.Y., Young,M.K., Lee,T.D. and
            Stevens,S.W.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   7  (bases 1 to 604)
  AUTHORS   Novakova,Z., Man,P., Novak,P., Hozak,P. and Hodny,Z.
  TITLE     Separation of nuclear protein complexes by blue native
            polyacrylamide gel electrophoresis
  JOURNAL   Electrophoresis 27 (7), 1277-1287 (2006)
   PUBMED   16502463
REFERENCE   8  (bases 1 to 604)
  AUTHORS   Will,C.L., Schneider,C., Hossbach,M., Urlaub,H., Rauhut,R.,
            Elbashir,S., Tuschl,T. and Luhrmann,R.
  TITLE     The human 18S U11/U12 snRNP contains a set of novel proteins not
            found in the U2-dependent spliceosome
  JOURNAL   RNA 10 (6), 929-941 (2004)
   PUBMED   15146077
REFERENCE   9  (bases 1 to 604)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   10 (bases 1 to 604)
  AUTHORS   McClain,M.T., Ramsland,P.A., Kaufman,K.M. and James,J.A.
  TITLE     Anti-sm autoantibodies in systemic lupus target highly basic
            surface structures of complexed spliceosomal autoantigens
  JOURNAL   J Immunol 168 (4), 2054-2062 (2002)
   PUBMED   11823543
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168781.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001109399.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168781.1, CF977737.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..604
                     /gene="Snrpd2"
                     /note="small nuclear ribonucleoprotein D2 polypeptide"
                     /db_xref="GeneID:680309"
                     /db_xref="RGD:1593018"
     exon            1..76
                     /gene="Snrpd2"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..431
                     /gene="Snrpd2"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein Sm D2"
                     /protein_id="NP_001102869.1"
                     /db_xref="GeneID:680309"
                     /db_xref="RGD:1593018"
                     /translation="MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLI
                     NCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKSGKGKKKSKPVNKDRYISKMFLR
                     GDSVIVVLRNPLIAGK"
     exon            77..256
                     /gene="Snrpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            257..538
                     /gene="Snrpd2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttctcttgc tgtgctccaa aggctaaagc aacgcgcttg gaggcgggag tgatctgcta
       61 gcgaaacctt caccatgagt ctcctcaata aacccaagag tgagatgacc ccagaggagc
      121 tgcagaagcg ggaggaggag gaattcaaca caggtcccct ctcggtgctc acacagtcgg
      181 tcaaaaacaa cacgcaagtg ctcattaact gtcgaaacaa caagaagctc ctgggccggg
      241 tgaaggcctt tgacaggcac tgcaacatgg tgctggaaaa tgtgaaggag atgtggactg
      301 aggtccccaa gagcggcaag ggcaagaaga agtccaagcc tgtcaacaag gaccgctaca
      361 tctccaagat gttcctgcgc ggggactcag tcattgtggt gctgcggaac ccgctcatcg
      421 ctggcaagta aactagaggc cagcctcagc ccgctgagag cctgctccct gcccagccaa
      481 gtcccgcaga gccctgccca atgagctaga aataaaaccc tgtgcttttt gttttttaaa
      541 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      601 aaaa
//
