LOCUS       NM_001106163             832 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein D1 polypeptide
            (Snrpd1), mRNA.
ACCESSION   NM_001106163 XM_001060646 XM_214621
VERSION     NM_001106163.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will
            CL, Urlaub H, Kastner B, Luhrmann R and Stark H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 832)
  AUTHORS   Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K,
            Urlaub H, Kastner B, Stark H and Luhrmann R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 832)
  AUTHORS   Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H,
            Luhrmann R and Stark H.
  TITLE     Molecular architecture of the human U4/U6.U5 tri-snRNP
  JOURNAL   Science 351 (6280), 1416-1420 (2016)
   PUBMED   26912367
REFERENCE   4  (bases 1 to 832)
  AUTHORS   Kondo Y, Oubridge C, van Roon AM and Nagai K.
  TITLE     Crystal structure of human U1 snRNP, a small nuclear
            ribonucleoprotein particle, reveals the mechanism of 5' splice site
            recognition
  JOURNAL   Elife 4, e04986 (2015)
   PUBMED   25555158
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 832)
  AUTHORS   Lin SJ, Chang KP, Hsu CW, Chi LM, Chien KY, Liang Y, Tsai MH, Lin
            YT and Yu JS.
  TITLE     Low-molecular-mass secretome profiling identifies C-C motif
            chemokine 5 as a potential plasma biomarker and therapeutic target
            for nasopharyngeal carcinoma
  JOURNAL   J Proteomics 94, 186-201 (2013)
   PUBMED   24080422
REFERENCE   6  (bases 1 to 832)
  AUTHORS   Riemekasten G, Langnickel D, Ebling FM, Karpouzas G, Kalsi J,
            Herberth G, Tsao BP, Henklein P, Langer S, Burmester GR, Radbruch
            A, Hiepe F and Hahn BH.
  TITLE     Identification and characterization of SmD183-119-reactive T cells
            that provide T cell help for pathogenic anti-double-stranded DNA
            antibodies
  JOURNAL   Arthritis Rheum 48 (2), 475-485 (2003)
   PUBMED   12571858
REFERENCE   7  (bases 1 to 832)
  AUTHORS   Riemekasten G, Weiss C, Schneider S, Thiel A, Bruns A, Schumann F,
            Blass S, Burmester GR and Hiepe F.
  TITLE     T cell reactivity against the SmD1(83-119) C terminal peptide in
            patients with systemic lupus erythematosus
  JOURNAL   Ann Rheum Dis 61 (9), 779-785 (2002)
   PUBMED   12176801
REFERENCE   8  (bases 1 to 832)
  AUTHORS   Jurica MS, Licklider LJ, Gygi SR, Grigorieff N and Moore MJ.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   9  (bases 1 to 832)
  AUTHORS   Jaekel HP, Klopsch T, Benkenstein B, Grobe N, Baldauf A, Schoessler
            W and Werle E.
  TITLE     Reactivities to the Sm autoantigenic complex and the synthetic
            SmD1-aa83-119 peptide in systemic lupus erythematosus and other
            autoimmune diseases
  JOURNAL   J Autoimmun 17 (4), 347-354 (2001)
   PUBMED   11771960
REFERENCE   10 (bases 1 to 832)
  AUTHORS   Habets WJ, Hoet MH, De Jong BA, Van der Kemp A and Van Venrooij WJ.
  TITLE     Mapping of B cell epitopes on small nuclear ribonucleoproteins that
            react with human autoantibodies as well as with
            experimentally-induced mouse monoclonal antibodies
  JOURNAL   J Immunol 143 (8), 2560-2566 (1989)
   PUBMED   2477448
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474073.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001060646.1, XM_214621.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167095.1, EV775769.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p13"
     gene            1..832
                     /gene="Snrpd1"
                     /note="small nuclear ribonucleoprotein D1 polypeptide"
                     /db_xref="GeneID:291794"
                     /db_xref="RGD:1306345"
     exon            1..131
                     /gene="Snrpd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..477
                     /gene="Snrpd1"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein Sm D1"
                     /protein_id="NP_001099633.1"
                     /db_xref="GeneID:291794"
                     /db_xref="RGD:1306345"
                     /translation="MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVK
                     MTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGR
                     GRGRGRGRGRGRGGPRR"
     exon            132..208
                     /gene="Snrpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            209..400
                     /gene="Snrpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            401..832
                     /gene="Snrpd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtcgcgcat ccgcaggtct ccgcgcgctc ttccggccat tcatactcct agtctgtggg
       61 tctttggagc ctgaattccg tggacagttg gactagaagg gagactgcgc cgctaggatg
      121 aagctcgtga gatttttgat gaaattgagt catgaaaccg taaccattga attgaagaat
      181 ggaacgcaag tccatggaac aatcacaggt gtagatgtca gcatgaatac gcaccttaaa
      241 gctgtgaaaa tgaccctgaa gaacagagag cctgtacagt tggaaacatt gagtattcga
      301 ggcaataaca ttcggtattt tattctacca gacagtttac ctctagatac actacttgtg
      361 gatgtcgaac ctaaagtgaa gtctaagaaa agagaggctg ttgcaggaag aggccgaggc
      421 cggggtagag gaagaggacg tggtcgtggc agaggaagag ggggtcctag gcgataatgt
      481 ctctcaagat tgctgtttca gattgataag gaatttgggg tattttttgt acaggttttg
      541 tttgtttgtc agtttttaat aaacataagg atagggacag agttgtctgc tgattatcaa
      601 attgaagttt tagcggctac tgtattcata gagtatgttc cgcatgaaat acatatgtac
      661 tgagcatcgg tttgattcct ttgagtccat tatttgggcc ccttttgaga tgaagtaaat
      721 tcttggtatt ttaataaagt tcttactggg atgagatcta aaactcatcc tctttagttt
      781 tactccatgg agccttagtg gtaaaagaaa aaaataaatg acttttcctg gg
//
