LOCUS       NM_001108592             919 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein polypeptide B2
            (Snrpb2), mRNA.
ACCESSION   NM_001108592 XM_001053334 XM_342528
VERSION     NM_001108592.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Bertram,K., Agafonov,D.E., Dybkov,O., Haselbach,D., Leelaram,M.N.,
            Will,C.L., Urlaub,H., Kastner,B., Luhrmann,R. and Stark,H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 919)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 919)
  AUTHORS   Rozanov,D.V., Savinov,A.Y., Williams,R., Liu,K., Golubkov,V.S.,
            Krajewski,S. and Strongin,A.Y.
  TITLE     Molecular signature of MT1-MMP: transactivation of the downstream
            universal gene network in cancer
  JOURNAL   Cancer Res 68 (11), 4086-4096 (2008)
   PUBMED   18519667
REFERENCE   4  (bases 1 to 919)
  AUTHORS   Chen,Y.I., Moore,R.E., Ge,H.Y., Young,M.K., Lee,T.D. and
            Stevens,S.W.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   5  (bases 1 to 919)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   6  (bases 1 to 919)
  AUTHORS   Neubauer,G., King,A., Rappsilber,J., Calvio,C., Watson,M., Ajuh,P.,
            Sleeman,J., Lamond,A. and Mann,M.
  TITLE     Mass spectrometry and EST-database searching allows
            characterization of the multi-protein spliceosome complex
  JOURNAL   Nat Genet 20 (1), 46-50 (1998)
   PUBMED   9731529
REFERENCE   7  (bases 1 to 919)
  AUTHORS   Guialis,A., Moraitou,M., Patrinou-Georgoula,M. and Dangli,A.
  TITLE     A novel 40S multi-snRNP complex isolated from rat liver nuclei
  JOURNAL   Nucleic Acids Res 19 (2), 287-296 (1991)
   PUBMED   1707521
REFERENCE   8  (bases 1 to 919)
  AUTHORS   Craft,J., Mimori,T., Olsen,T.L. and Hardin,J.A.
  TITLE     The U2 small nuclear ribonucleoprotein particle as an autoantigen.
            Analysis with sera from patients with overlap syndromes
  JOURNAL   J Clin Invest 81 (6), 1716-1724 (1988)
   PUBMED   2968364
REFERENCE   9  (bases 1 to 919)
  AUTHORS   Habets,W.J., Sillekens,P.T., Hoet,M.H., Schalken,J.A.,
            Roebroek,A.J., Leunissen,J.A., van de Ven,W.J. and van
            Venrooij,W.J.
  TITLE     Analysis of a cDNA clone expressing a human autoimmune antigen:
            full-length sequence of the U2 small nuclear RNA-associated B'
            antigen
  JOURNAL   Proc Natl Acad Sci U S A 84 (8), 2421-2425 (1987)
   PUBMED   2951739
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001108592.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168760.1, FQ213679.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                JAXUCZ010000003.1  150852834-150852861
            29-117              JAXUCZ010000003.1  150854545-150854633
            118-290             JAXUCZ010000003.1  150855098-150855270
            291-431             JAXUCZ010000003.1  150858881-150859021
            432-482             JAXUCZ010000003.1  150860001-150860051
            483-571             JAXUCZ010000003.1  150861486-150861574
            572-919             JAXUCZ010000003.1  150862015-150862362
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..919
                     /gene="Snrpb2"
                     /note="small nuclear ribonucleoprotein polypeptide B2"
                     /db_xref="GeneID:362223"
                     /db_xref="RGD:1310194"
     exon            1..28
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            29..117
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..731
                     /gene="Snrpb2"
                     /note="U2 small nuclear ribonucleoprotein B; small nuclear
                     ribonucleoprotein polypeptide B''"
                     /codon_start=1
                     /product="U2 small nuclear ribonucleoprotein B''"
                     /protein_id="NP_001102062.1"
                     /db_xref="GeneID:362223"
                     /db_xref="RGD:1310194"
                     /translation="MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALK
                     TMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKE
                     KKKEKKKAKTMEQAAAAANKKPGQGTPNSANTQGNAAPNPQVPDYPPNYILFLNNLPE
                     ETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAM
                     KITYAKK"
     exon            118..290
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            291..431
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            432..482
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            483..571
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
     exon            572..919
                     /gene="Snrpb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcttcaagc ggaccgcgcc ggcttcaggc tacttgaaga gttttaccca aacatggata
       61 tcagaccaaa tcacacgatt tatatcaaca acatgaatga caaaattaaa aaagaagaat
      121 tgaagagatc cctgtatgcc ctgttttctc agtttggaca tgtggtagat attgtggctt
      181 taaagaccat gaagatgaga gggcaggctt ttgttatatt taaggaactg ggctcatcca
      241 caaatgcttt gagacagtta caaggatttc cattttatgg taaaccaatg agaattcagt
      301 acgcaaaaac agattccgat ataatatcta aaatgcgtgg tactttcgct gacaaggaaa
      361 agaaaaagga aaagaagaaa gctaaaacca tggaacaggc tgcagcagct gcaaacaaga
      421 agcctggtca gggaacacca aattcagcta atactcaagg aaatgcagca ccaaatcctc
      481 aggtccctga ttaccctcca aactatatcc tgttccttaa taacttacca gaagagacga
      541 atgagatgat gttatccatg ttgttcaacc agttccctgg tttcaaggaa gttcgcctgg
      601 tcccggggag acatgatatt gcgtttgtag aatttgaaaa tgatgggcag gctggagcag
      661 ccagagatgc tctgcaaggg tttaagatca caccatccca tgccatgaag attacctatg
      721 ccaagaagta acacggggag tgccagtttt aaaggacttg gtattattta tagcttttgt
      781 tttaattata ttcagtcaag ttgtttgaaa tggttggaag tgaaggtgaa gttttggaaa
      841 aagagtcacc taattttttt ttagttttgg tgaactatga aatacaaagc cttaattttg
      901 tacaataaac ttttatttg
//
