LOCUS       NM_134358               1106 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus small nuclear ribonucleoprotein polypeptides B
            and B1 (Snrpb), mRNA.
ACCESSION   NM_134358 XM_001059527 XM_001079072
VERSION     NM_134358.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Bertram,K., Agafonov,D.E., Dybkov,O., Haselbach,D., Leelaram,M.N.,
            Will,C.L., Urlaub,H., Kastner,B., Luhrmann,R. and Stark,H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 1106)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   3  (bases 1 to 1106)
  AUTHORS   Tooley,M., Lynch,D., Bernier,F., Parboosingh,J., Bhoj,E.,
            Zackai,E., Calder,A., Itasaki,N., Wakeling,E., Scott,R., Lees,M.,
            Clayton-Smith,J., Blyth,M., Morton,J., Shears,D., Kini,U.,
            Homfray,T., Clarke,A., Barnicoat,A., Wallis,C., Hewitson,R.,
            Offiah,A., Saunders,M., Langton-Hewer,S., Hilliard,T., Davis,P. and
            Smithson,S.
  TITLE     Cerebro-costo-mandibular syndrome: Clinical, radiological, and
            genetic findings
  JOURNAL   Am J Med Genet A 170A (5), 1115-1126 (2016)
   PUBMED   26971886
REFERENCE   4  (bases 1 to 1106)
  AUTHORS   Agafonov,D.E., Kastner,B., Dybkov,O., Hofele,R.V., Liu,W.T.,
            Urlaub,H., Luhrmann,R. and Stark,H.
  TITLE     Molecular architecture of the human U4/U6.U5 tri-snRNP
  JOURNAL   Science 351 (6280), 1416-1420 (2016)
   PUBMED   26912367
REFERENCE   5  (bases 1 to 1106)
  AUTHORS   Kondo,Y., Oubridge,C., van Roon,A.M. and Nagai,K.
  TITLE     Crystal structure of human U1 snRNP, a small nuclear
            ribonucleoprotein particle, reveals the mechanism of 5' splice site
            recognition
  JOURNAL   Elife 4, e04986 (2015)
   PUBMED   25555158
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1106)
  AUTHORS   Pillai,R.S., Will,C.L., Luhrmann,R., Schumperli,D. and Muller,B.
  TITLE     Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain
            Lsm10, a new 14 kDa Sm D1-like protein
  JOURNAL   EMBO J 20 (19), 5470-5479 (2001)
   PUBMED   11574479
REFERENCE   7  (bases 1 to 1106)
  AUTHORS   Huntriss,J.D., Latchman,D.S. and Williams,D.G.
  TITLE     The snRNP core protein SmB and tissue-specific SmN protein are
            differentially distributed between snRNP particles
  JOURNAL   Nucleic Acids Res 21 (17), 4047-4053 (1993)
   PUBMED   8371979
REFERENCE   8  (bases 1 to 1106)
  AUTHORS   Grimaldi,K., Horn,D.A., Hudson,L.D., Terenghi,G., Barton,P.,
            Polak,J.M. and Latchman,D.S.
  TITLE     Expression of the SmN splicing protein is developmentally regulated
            in the rodent brain but not in the rodent heart
  JOURNAL   Dev Biol 156 (2), 319-323 (1993)
   PUBMED   8462734
REFERENCE   9  (bases 1 to 1106)
  AUTHORS   Li,S., Klein,E.S., Russo,A.F., Simmons,D.M. and Rosenfeld,M.G.
  TITLE     Isolation of cDNA clones encoding small nuclear
            ribonucleoparticle-associated proteins with different tissue
            specificities
  JOURNAL   Proc Natl Acad Sci U S A 86 (24), 9778-9782 (1989)
   PUBMED   2532363
REFERENCE   10 (bases 1 to 1106)
  AUTHORS   Craft,J., Mimori,T., Olsen,T.L. and Hardin,J.A.
  TITLE     The U2 small nuclear ribonucleoprotein particle as an autoantigen.
            Analysis with sera from patients with overlap syndromes
  JOURNAL   J Clin Invest 81 (6), 1716-1724 (1988)
   PUBMED   2968364
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158686.1.
            
            On or before Jun 5, 2008 this sequence version replaced
            XM_001059527.1, XM_001079072.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158686.1, FQ220740.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1106
                     /gene="Snrpb"
                     /note="small nuclear ribonucleoprotein polypeptides B and
                     B1"
                     /db_xref="GeneID:171365"
                     /db_xref="RGD:621301"
     exon            1..99
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..792
                     /gene="Snrpb"
                     /note="smB; SM11; sm-B; snRNP-B; sm protein B"
                     /codon_start=1
                     /product="small nuclear ribonucleoprotein-associated
                     protein B"
                     /protein_id="NP_599185.1"
                     /db_xref="GeneID:171365"
                     /db_xref="RGD:621301"
                     /translation="MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCD
                     CDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAG
                     GPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATAS
                     IAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPP
                     GMRPPPPGMRGLL"
     exon            100..251
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     exon            252..363
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     exon            364..516
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     exon            517..655
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     exon            656..781
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
     exon            782..1078
                     /gene="Snrpb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttccgttag cggcggcggg aatctaggtg ctggctgccg actaggcctc tgtggaagcg
       61 aatccggcgg gaatctgagc catccgagcc gccaccatga cggtgggcaa gagcagcaag
      121 atgctgcagc acatcgacta caggatgagg tgcatcctgc aagatggccg gatcttcatc
      181 gggaccttca aagcttttga caagcatatg aacttgatcc tctgtgactg tgatgagttc
      241 aggaagatca agccaaagaa ctccaaacaa gcagaaagag aagagaagcg agtccttggt
      301 ctggtgttgc ttcgaggaga gaacctggtc tccatgacag tagaaggacc tcctcccaaa
      361 gatactggca ttgcccgagt gccacttgct ggagctgctg gggggccagg catcggcagg
      421 gctgctggca gaggaatccc ggcgggtgtg cccatgcccc aggctcctgc agggcttgct
      481 ggaccagtgc gaggtgttgg agggccgtcc cagcaggtga tgaccccaca aggaagaggc
      541 actgtggcag ctgctgcagc tgcagccaca gccagtattg caggagcccc aactcagtac
      601 ccacctggtc gtgggggtcc tcctccacct atgggccgag gggcacctcc tccaggtatg
      661 atgggcccac ctcctggcat gaggcctccc atgggtcccc caatggggat ccctcctggc
      721 cgaggaactc caatgggcat gccccctcct gggatgcgac ctcctcctcc aggcatgcga
      781 ggtctgcttt gatcttcgca cagcattatg tcagtagctc cgaagagaca tggaccctat
      841 tccccagggt caggttacca cagacctgtt tgtttgttat gctgtttatg gagtcttact
      901 ggagcgtctg gtttcccttt cagggctccc tccctgggaa atgtgccctc cgaggcccta
      961 gactcatctt ggtcctcctc agctccttgc ctgtttccca aaaggctgta catagtcctt
     1021 ttttttttct gtggcccatg aagctggttt ataataaact aagagactgt tatacataaa
     1081 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
