LOCUS       NM_001034083            2931 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus stannin (Snn), mRNA.
ACCESSION   NM_001034083 XM_001052997
VERSION     NM_001034083.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2931)
  AUTHORS   Buck-Koehntop,B.A., Mascioni,A., Buffy,J.J. and Veglia,G.
  TITLE     Structure, dynamics, and membrane topology of stannin: a mediator
            of neuronal cell apoptosis induced by trimethyltin chloride
  JOURNAL   J Mol Biol 354 (3), 652-665 (2005)
   PUBMED   16246365
REFERENCE   2  (bases 1 to 2931)
  AUTHORS   Davidson,C.E., Reese,B.E., Billingsley,M.L. and Yun,J.K.
  TITLE     The protein stannin binds 14-3-3zeta and modulates
            mitogen-activated protein kinase signaling
  JOURNAL   Brain Res Mol Brain Res 138 (2), 256-263 (2005)
   PUBMED   15923056
  REMARK    GeneRIF: Together, these findings indicate a role of Stannin in
            modulation of MAPK signaling pathways through its interactions with
            14-3-3zeta
REFERENCE   3  (bases 1 to 2931)
  AUTHORS   Dejneka,N.S., Patanow,C.M., Polavarapu,R., Toggas,S.M., Krady,J.K.
            and Billingsley,M.L.
  TITLE     Localization and characterization of stannin: relationship to
            cellular sensitivity to organotin compounds
  JOURNAL   Neurochem Int 31 (6), 801-815 (1997)
   PUBMED   9413842
REFERENCE   4  (bases 1 to 2931)
  AUTHORS   Toggas,S.M., Krady,J.K. and Billingsley,M.L.
  TITLE     Molecular neurotoxicology of trimethyltin: identification of
            stannin, a novel protein expressed in trimethyltin-sensitive cells
  JOURNAL   Mol Pharmacol 42 (1), 44-56 (1992)
   PUBMED   1635553
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100111.1.
            
            On Jun 25, 2006 this sequence version replaced XM_001052997.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100111.1, M81639.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2931
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q11"
     gene            1..2931
                     /gene="Snn"
                     /note="stannin"
                     /db_xref="GeneID:29140"
                     /db_xref="RGD:3730"
     exon            1..77
                     /gene="Snn"
                     /inference="alignment:Splign:2.1.0"
     exon            78..2906
                     /gene="Snn"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..431
                     /gene="Snn"
                     /codon_start=1
                     /product="stannin"
                     /protein_id="NP_001029255.1"
                     /db_xref="GeneID:29140"
                     /db_xref="RGD:3730"
                     /translation="MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQS
                     EDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTANSPEVHG"
ORIGIN      
        1 cccggctggc gcgcgggcgg agccggggcg gcagagctgc tgctggctga ttgcaccgga
       61 ctgcgggccg cgacatggac tgtcctgtgc agcccgaatc ccggcctcgt tgagctaggc
      121 acaccaagag ctttccacca aagaagcccc tccaagcact gaccatgtct attatggacc
      181 acagccccac gactggggta gtcacagtca ttgtcatcct catcgccata gctgccctgg
      241 gggccttgat cctcggctgc tggtgctacc tgcggctgca gcgcatcagc cagtcagagg
      301 atgaggagag catcgtgggc gatggcgaga caaaggagcc ctttctactg gtgcagtatt
      361 ctgccaaggg gccatgtgtg gaaagaaagg ccaaattgat gaccgccaac agcccggaag
      421 tgcatggctg agcggggctg cgaaggccat ggttctgttt gcagccagcc cagaagcact
      481 gagagggcag aagcagacat gttgctatgt gagaggggtt gacacttgct ggcatggtct
      541 ccttgggctt tgacatcgca tgcactgact ccaggtccca gctcttctgg cctcctcctc
      601 agcctcttgg tgggctgtcc attgcaggca gtgggcaggc ctgaccctgc tggggttcat
      661 ggcctctcag cgctttcctt acttgaatgt tttagctgag cctgttcttg atggagctac
      721 tactgtaacg cgtgaactaa ccaacctgtg aactgtaaat aggcccagaa gcacgtgttt
      781 taagcctttt tgccaatttt taaaaaacac cagatggatg gactggcttg ataatgactg
      841 tactcacgtg agctgaggta tgatcatgga gggtcttcga ctggtcaggc cccaggtgcc
      901 cttggcaggg tgcactgagg tcttagcaat gcatacagaa gggaggtgaa aggtgaaact
      961 ggggtgcttc aacttgctta gcaatggagg aaaaccgcac ctctcccttt ctttacttca
     1021 gctttgttat atagcagtgt gtagatctgg cagttactgc gaggaagctg ttaatgcgtg
     1081 cttggaagcc tatgaaggac atctcgagag tcctgagggt tgccaggcag cttagcagag
     1141 cagtctcttg ccctttggtt ttgagcatgc ccagtacagc ccttcaacac aggctttgca
     1201 gaaaactgtt ctggtcctct ggaaacacca gagcccatgg tagctacttg aagtctgaaa
     1261 cccagttggc ccaggaaggc aaggtttggt ttttgtattt aatattttct gcactggaat
     1321 gagggttggg ggtaggggtg gctccccccc cccccctttt cacaagtgag cttccttttc
     1381 ttctcccatg ggtattgggt ttcactttga tccttggggc tttgtagaca gagctcccta
     1441 tcccagctct caaggtactg tgtgccacag aaggtccttt ctagtgtgca tacgagcact
     1501 tacaacagag ttaccaggag tccaagttca gggcccagtt ctcactggta agggagccag
     1561 cagcatgcct ccaggctatt tctgatgtct ataagcttgc tcagatgtta acccaccacc
     1621 acaatacgca ttctaaacta ttacgagtaa acctgactgt gctggcgccc ttggtgatga
     1681 gtaggtggct agctagccct ggcagcagag agcttcaggc tagtctgggg acagctttaa
     1741 aaagcatgta aacctaatcc attttctaga accccaaggg aggagctgta gggaacactt
     1801 ctttttagca gtgtatacca atatgtggac aggggaggca gatgctaaga aacagtgtaa
     1861 ggtaaggaag gacagctaaa aaggccattt gtgaaggtag gaacaagaca gctcaggtga
     1921 gcagctccgg cagaaacagc tgaagaaaga ctcttgaaca ctggtgagat agctaagtca
     1981 cacaagaggt aggcaaggac ggactggcca cagcaggggc tgctaaggct ggcttggatg
     2041 tgttagacct gggagcagtg actctccagt tctaggaggg gaacagaagg tttcaaagga
     2101 tctgccctgc agttggctga ggctgaaggc tctgacccat tcccgcccca cacccacctt
     2161 tctacctctg cgtcttgcag ccagcagcct aaacactgct gaccctttcc tctaccatcc
     2221 actgacctct gcaccgaagt ttgagcatgt gcatcaccgc acgatgcagg ctgcagctgg
     2281 tattctgctg atgaagtctg tttttcagac atcatcacat tcttatcatt tacactttgg
     2341 gggagcttcc tatcacacac cccctccccc ccccgccctc gttgccaggg ggtatttcaa
     2401 gtttgagtta gtccatccag aggggcatga gtgagtaagt tcaggcactg tggggcactg
     2461 gtggggtcac agggggagaa taaggaccta tggaactatt gaacaaccat gcaagtcttc
     2521 cctgcccttg gttatcacta gctacctttt caagtgtgca ctggagccac acgctgcaat
     2581 ggttagtgag tcatgacttc ccttcagatt cttcccagta gtgtaactgt tatggtcagg
     2641 tcttctgatg agcaagaggc tagcctttca tcctggggag catgcaggaa ctccgaggct
     2701 aagccactga agcgaggact gacatttcta gatatatgtt caagcagacc gtgctactgt
     2761 tgtgtctcaa agctaccagt ttgtgcaata agtggaaggg atgacattcc tgatcaataa
     2821 atgctgaatg acattcaagt tcattttgta gaccactgag aaaatcttta tttacaataa
     2881 atttcaataa aatttgcata actataaaaa aaaaaaaaaa aaaaaaaaaa a
//
