LOCUS       NM_001014069            2338 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Smad nuclear interacting protein 1 (Snip1), mRNA.
ACCESSION   NM_001014069 XM_233518
VERSION     NM_001014069.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2338)
  AUTHORS   Zhang,X., Yan,C., Zhan,X., Li,L., Lei,J. and Shi,Y.
  TITLE     Structure of the human activated spliceosome in three
            conformational states
  JOURNAL   Cell Res 28 (3), 307-322 (2018)
   PUBMED   29360106
REFERENCE   2  (bases 1 to 2338)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
REFERENCE   3  (bases 1 to 2338)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2338)
  AUTHORS   Yu,B., Bi,L., Zheng,B., Ji,L., Chevalier,D., Agarwal,M.,
            Ramachandran,V., Li,W., Lagrange,T., Walker,J.C. and Chen,X.
  TITLE     The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans
            act in small RNA biogenesis
  JOURNAL   Proc Natl Acad Sci U S A 105 (29), 10073-10078 (2008)
   PUBMED   18632581
REFERENCE   5  (bases 1 to 2338)
  AUTHORS   Kim,R.H., Flanders,K.C., Birkey Reffey,S., Anderson,L.A.,
            Duckett,C.S., Perkins,N.D. and Roberts,A.B.
  TITLE     SNIP1 inhibits NF-kappa B signaling by competing for its binding to
            the C/H1 domain of CBP/p300 transcriptional co-activators
  JOURNAL   J Biol Chem 276 (49), 46297-46304 (2001)
   PUBMED   11567019
REFERENCE   6  (bases 1 to 2338)
  AUTHORS   Kim,R.H., Wang,D., Tsang,M., Martin,J., Huff,C., de
            Caestecker,M.P., Parks,W.T., Meng,X., Lechleider,R.J., Wang,T. and
            Roberts,A.B.
  TITLE     A novel smad nuclear interacting protein, SNIP1, suppresses
            p300-dependent TGF-beta signal transduction
  JOURNAL   Genes Dev 14 (13), 1605-1616 (2000)
   PUBMED   10887155
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087118.1.
            
            On Apr 20, 2005 this sequence version replaced XM_233518.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087118.1, SRR8487231.77247.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2338
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2338
                     /gene="Snip1"
                     /note="Smad nuclear interacting protein 1"
                     /db_xref="GeneID:313588"
                     /db_xref="RGD:1359268"
     exon            1..245
                     /gene="Snip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1203
                     /gene="Snip1"
                     /codon_start=1
                     /product="smad nuclear interacting protein 1"
                     /protein_id="NP_001014091.1"
                     /db_xref="GeneID:313588"
                     /db_xref="RGD:1359268"
                     /translation="MKAGKSERERSSRRRHRSGDALATVVVKQERLSPEPVAHRRPDA
                     PAASPPPPAAESGSAGHRGSRARGASRSPAKKKSKSSGRRSKSPRTKRSRSPHYSTVK
                     VKQEREDHPRRGREDRQHRELSEQEHRRARNSERDRHRGHARQRRSSDERPVSGQGRD
                     RDSQILQAQEEERDFNNARRREHRQQNESAGAEAQEVIPRPAGNKNKEVPVKEKPSFE
                     LSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGR
                     HRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKR
                     IEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDEEEEEEMVSDSS"
     exon            246..348
                     /gene="Snip1"
                     /inference="alignment:Splign:2.1.0"
     exon            349..932
                     /gene="Snip1"
                     /inference="alignment:Splign:2.1.0"
     exon            933..2307
                     /gene="Snip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gactgtgcaa gtgactctcg gccgggccgc aggatgaaag cggggaagag cgagcgggag
       61 cgaagcagcc ggcggcgaca ccggtcaggc gacgctttgg cgaccgtagt agtgaagcag
      121 gaacgtctaa gccccgaacc cgtcgcacac cgccgacctg acgctccagc cgctagcccg
      181 cccccgcccg ccgccgagtc gggctcggct ggtcaccgcg ggagccgagc ccggggagcg
      241 agccggtccc cagccaaaaa gaaaagcaag tcctccggca gaagaagcaa gtctcctcgg
      301 actaagagaa gccggagtcc ccactactcc acggtcaaag tgaagcagga acgggaggac
      361 catccacgga gaggacgaga ggataggcag caccgggagt tatcagaaca ggagcacagg
      421 agagcacgga acagcgagcg agatcggcac cggggccatg cccgccaaag gaggagctct
      481 gatgagaggc ctgtcagtgg gcagggtcgg gatagagaca gccagatcct gcaggcccag
      541 gaagaagaga gggactttaa taatgccagg cgccgggagc accgccagca gaatgagagt
      601 gctggcgctg aggctcagga ggtgatccct cgccctgctg gtaacaagaa caaagaggtg
      661 cctgttaaag aaaaaccaag ctttgaactt tctggggcac ttcttgagga cactaatacc
      721 ttccggggtg tggtcattaa atacagtgag cccccagaag cccgcatccc caaaaaacgg
      781 tggcgtctct acccctttaa aaatgatgag gtgcttccag tcatgtacat ccatcggcag
      841 agtgcgtacc tgctggggag acatcgccgc atcgcggaca ttcctatcga ccatccctct
      901 tgctcaaagc aacatgcagt cttccagtac cggcttgtgg agtacacccg tgctgatggg
      961 acggttggtc ggagggtgaa gccctacatc attgaccttg gctcaggcaa cggaacattc
     1021 ttgaacaaca agcgtattga gccacagaga tactatgaac tgaaagaaaa agatgtactt
     1081 aaatttgggt tcagcagcag agaatatgtc ttgcttcatg agtcttcaga cacctctgaa
     1141 cttgacagga aggaagatga agatgaggag gaggaggagg aaatggtgtc tgacagcagc
     1201 tgagaagcag cctccactat tagaaaccgt ccctaccgga ggccgtgggg tgactccagc
     1261 gcctcttctt gccttaagtc tttcctctat tgctgcccag cttatgttgc agtatgagag
     1321 ctgtcacttc gtgttttgtt gaacttggca cagcagcggc ctgcctgtgg gcgcttgttt
     1381 tcagaagaat ctcaccaatt acagcatgtc gagtttggtc agagtgtgtg gctgcggtgg
     1441 gtgccttcag aactgctgcc ataggaaaca gcccttggaa aggggattgt gacttctctt
     1501 tgtacagttt cttatttata tagttgttga gctttgtgaa ccaggagttt tgttttgggg
     1561 acaaacccta gagtagagaa tctcagtcag ctttggatgt caccaaaaca acctccagca
     1621 tataccaaag ctttgacctg gttcagctct tgagtcacag aagttggttt tgcacttcgt
     1681 ttttttgggg ggtgacagtt taccacgtga cctctttatt ggctgtctgc gataaacaga
     1741 cactgtgatg cctgtgtaga catgactgta gggaggtcat ggcttctact gacaggtgct
     1801 ggtgtcatgt catacactgg gctgtagatc cgcatcctct gaggattcct gattgctcca
     1861 tgaagcagac ataatggttt gatcatctgg tcttttcttc agctttgcat ttttattccg
     1921 atgtcacctc tcttctccct ttgagaaaca ctacactgac tttctgggcg gggccttgct
     1981 ggggtctctg ggtgtatatg tgtctaaagg aagtcatgta gcttccatat ttctgcttca
     2041 tctttgacca tgtgttcgta ttcaacttcc aagggtagaa agtaagggac agcctaggtc
     2101 ttcccacctg gggtctgtgt gagtagaaag atactccttc cttccggtct gtgtgcttca
     2161 gagctatgtg ctgattttca tatgacagtg ttttgtgata taaataatac cacatgatag
     2221 gcaaaggcct gtctgcattt ggagagcagg ttttcattta tatgtatttt tgagattaaa
     2281 aaaataaaat ttgtaaatat agcctcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
