LOCUS       NM_001007804             952 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus SNF8 subunit of ESCRT-II (Snf8), mRNA.
ACCESSION   NM_001007804 XM_213441
VERSION     NM_001007804.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Ghoujal,B., Milev,M.P., Ajamian,L., Abel,K. and Mouland,A.J.
  TITLE     ESCRT-II's involvement in HIV-1 genomic RNA trafficking and
            assembly
  JOURNAL   Biol Cell 104 (12), 706-721 (2012)
   PUBMED   22978549
REFERENCE   2  (bases 1 to 952)
  AUTHORS   Carrasquillo,R., Tian,D., Krishna,S., Pollak,M.R., Greka,A. and
            Schlondorff,J.
  TITLE     SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and
            enhances its channel activity
  JOURNAL   BMC Cell Biol 13, 33 (2012)
   PUBMED   23171048
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 952)
  AUTHORS   Baietti,M.F., Zhang,Z., Mortier,E., Melchior,A., Degeest,G.,
            Geeraerts,A., Ivarsson,Y., Depoortere,F., Coomans,C., Vermeiren,E.,
            Zimmermann,P. and David,G.
  TITLE     Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
  JOURNAL   Nat Cell Biol 14 (7), 677-685 (2012)
   PUBMED   22660413
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 952)
  AUTHORS   Rusten,T.E. and Stenmark,H.
  TITLE     How do ESCRT proteins control autophagy?
  JOURNAL   J Cell Sci 122 (Pt 13), 2179-2183 (2009)
   PUBMED   19535733
REFERENCE   5  (bases 1 to 952)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 952)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   7  (bases 1 to 952)
  AUTHORS   Martin-Serrano,J., Yarovoy,A., Perez-Caballero,D. and Bieniasz,P.D.
  TITLE     Divergent retroviral late-budding domains recruit vacuolar protein
            sorting factors by using alternative adaptor proteins
  JOURNAL   Proc Natl Acad Sci U S A 100 (21), 12414-12419 (2003)
   PUBMED   14519844
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):152845.
            Yaravoy, A [corrected to Yarovoy, A]]
REFERENCE   8  (bases 1 to 952)
  AUTHORS   von Schwedler,U.K., Stuchell,M., Muller,B., Ward,D.M., Chung,H.Y.,
            Morita,E., Wang,H.E., Davis,T., He,G.P., Cimbora,D.M., Scott,A.,
            Krausslich,H.G., Kaplan,J., Morham,S.G. and Sundquist,W.I.
  TITLE     The protein network of HIV budding
  JOURNAL   Cell 114 (6), 701-713 (2003)
   PUBMED   14505570
REFERENCE   9  (bases 1 to 952)
  AUTHORS   Kamura,T., Burian,D., Khalili,H., Schmidt,S.L., Sato,S., Liu,W.J.,
            Conrad,M.N., Conaway,R.C., Conaway,J.W. and Shilatifard,A.
  TITLE     Cloning and characterization of ELL-associated proteins EAP45 and
            EAP20. a role for yeast EAP-like proteins in regulation of gene
            expression by glucose
  JOURNAL   J Biol Chem 276 (19), 16528-16533 (2001)
   PUBMED   11278625
REFERENCE   10 (bases 1 to 952)
  AUTHORS   Schmidt,A.E., Miller,T., Schmidt,S.L., Shiekhattar,R. and
            Shilatifard,A.
  TITLE     Cloning and characterization of the EAP30 subunit of the ELL
            complex that confers derepression of transcription by RNA
            polymerase II
  JOURNAL   J Biol Chem 274 (31), 21981-21985 (1999)
   PUBMED   10419521
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 27, 2022 this sequence version replaced NM_001007804.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086364.1, SRR26643429.38575.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               JAXUCZ010000010.1  81481057-81481202
            147-197             JAXUCZ010000010.1  81481477-81481527
            198-336             JAXUCZ010000010.1  81487115-81487253
            337-441             JAXUCZ010000010.1  81488353-81488457
            442-514             JAXUCZ010000010.1  81489678-81489750
            515-656             JAXUCZ010000010.1  81491473-81491614
            657-731             JAXUCZ010000010.1  81492350-81492424
            732-952             JAXUCZ010000010.1  81493210-81493430
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..952
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /note="SNF8 subunit of ESCRT-II"
                     /db_xref="GeneID:287645"
                     /db_xref="RGD:1310144"
     exon            1..146
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..869
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /note="ESCRT-II complex subunit VPS22; ELL-associated
                     protein of 30 kDa; EAP30 subunit of ELL complex; SNF8,
                     ESCRT-II complex subunit, homolog"
                     /codon_start=1
                     /product="vacuolar-sorting protein SNF8"
                     /protein_id="NP_001007805.1"
                     /db_xref="GeneID:287645"
                     /db_xref="RGD:1310144"
                     /translation="MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFK
                     TNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGV
                     QIIEVCLALKHRNGGLITLEELHQQVLKGRGKFAQDVSQDDLIRAIKKLKALGTGFGI
                     IPVGGTYLIQSVPAELNMDHTVVLQLAEKNGYVTVSEIKASLKWETERARQVLEHLLK
                     EGLAWLDLQAPGEAHYWLPALFTDLYSQEISAEEAKEVFP"
     exon            147..197
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            198..336
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            337..441
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            442..514
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            515..656
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            657..731
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
     exon            732..952
                     /gene="Snf8"
                     /gene_synonym="D11moh34; RGD1310144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acccggcttc cgtgttggga gctggctaca gaacctggga cgcggagagc tggggttggg
       61 gcagcggggc ggcccgcggg cctggggtgg ggatgcaccg gcgcggggtg ggagctggcg
      121 ccattgccaa gaagaaactc gccgaggcca agtataagga gcgagggact gtcttggctg
      181 aggaccagct ggctcagatg tcaaaacagt tggacatgtt caagaccaac ctagaagaat
      241 ttgccagcaa gcacaagcaa gagatccgga agaatcctga gttccgagtt cagttccagg
      301 acatgtgtgc taccattggg gtggatcctc tggcctctgg aaaaggattt tggtctgaga
      361 tgctgggtgt tggggacttc tattatgaac tgggcgtcca gattattgaa gtgtgcctgg
      421 ccctaaaaca tcggaacgga ggtctgataa ctctggagga gctacatcag caggtgttaa
      481 aaggaagggg caagtttgct caggatgtca gccaagacga cctgatcagg gccatcaaga
      541 agctgaaagc actgggcact ggatttggca tcatccctgt gggaggaact tacctcattc
      601 agtctgttcc agctgagctc aatatggatc acactgttgt gctgcagctg gccgagaaaa
      661 acggttatgt gactgtcagt gaaatcaaag ccagtcttaa atgggagacg gagcgagcac
      721 ggcaagtgct ggaacacctg ctgaaggaag gactggcctg gctggatctg caggcaccag
      781 gggaggccca ctactggctg ccagctctct tcacagatct ctactcccag gagatatcag
      841 ctgaggaggc caaagaagtc tttccttgac tgagtgtgga gggatataca gcagcaggcc
      901 cgaagacgtc ctgcctgtga ataaacctgg acaattctgt ttataaaaaa aa
//
