LOCUS       NM_001399736             589 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus single-pass membrane protein with aspartate-rich
            tail 1 (Smdt1), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001399736 XM_235517
VERSION     NM_001399736.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 589)
  AUTHORS   Konig,T., Troder,S.E., Bakka,K., Korwitz,A., Richter-Dennerlein,R.,
            Lampe,P.A., Patron,M., Muhlmeister,M., Guerrero-Castillo,S.,
            Brandt,U., Decker,T., Lauria,I., Paggio,A., Rizzuto,R.,
            Rugarli,E.I., De Stefani,D. and Langer,T.
  TITLE     The m-AAA Protease Associated with Neurodegeneration Limits MCU
            Activity in Mitochondria
  JOURNAL   Mol Cell 64 (1), 148-162 (2016)
   PUBMED   27642048
REFERENCE   2  (bases 1 to 589)
  AUTHORS   Tsai,M.F., Phillips,C.B., Ranaghan,M., Tsai,C.W., Wu,Y.,
            Willliams,C. and Miller,C.
  TITLE     Dual functions of a small regulatory subunit in the mitochondrial
            calcium uniporter complex
  JOURNAL   Elife 5, e15545 (2016)
   PUBMED   27099988
  REMARK    Erratum:[Elife. 2017 Mar 02;6:. PMID: 28253172]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 589)
  AUTHORS   Sancak,Y., Markhard,A.L., Kitami,T., Kovacs-Bogdan,E., Kamer,K.J.,
            Udeshi,N.D., Carr,S.A., Chaudhuri,D., Clapham,D.E., Li,A.A.,
            Calvo,S.E., Goldberger,O. and Mootha,V.K.
  TITLE     EMRE is an essential component of the mitochondrial calcium
            uniporter complex
  JOURNAL   Science 342 (6164), 1379-1382 (2013)
   PUBMED   24231807
REFERENCE   4  (bases 1 to 589)
  AUTHORS   Tsai,L.C., Chan,G.C., Nangle,S.N., Shimizu-Albergine,M.,
            Jones,G.L., Storm,D.R., Beavo,J.A. and Zweifel,L.S.
  TITLE     Inactivation of Pde8b enhances memory, motor performance, and
            protects against age-induced motor coordination decay
  JOURNAL   Genes Brain Behav 11 (7), 837-847 (2012)
   PUBMED   22925203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jan 13, 2022 this sequence version replaced XM_235517.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB324536.1, CB609153.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-222               JAXUCZ010000007.1  115742240-115742461
            223-363             JAXUCZ010000007.1  115744100-115744240
            364-589             JAXUCZ010000007.1  115745098-115745323
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..589
                     /gene="Smdt1"
                     /gene_synonym="RGD1311310"
                     /note="single-pass membrane protein with aspartate-rich
                     tail 1"
                     /db_xref="GeneID:315166"
                     /db_xref="RGD:1311310"
     exon            1..222
                     /gene="Smdt1"
                     /gene_synonym="RGD1311310"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..360
                     /gene="Smdt1"
                     /gene_synonym="RGD1311310"
                     /codon_start=1
                     /product="essential MCU regulator, mitochondrial"
                     /protein_id="NP_001386665.1"
                     /db_xref="GeneID:315166"
                     /db_xref="RGD:1311310"
                     /translation="MASAAARRLAWLSVRPGALWTGPRGRRSGDVYTVPGSSGLSQVP
                     SRSVIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKNFAALLEEHDIFVPED
                     DDDDD"
     exon            223..363
                     /gene="Smdt1"
                     /gene_synonym="RGD1311310"
                     /inference="alignment:Splign:2.1.0"
     exon            364..589
                     /gene="Smdt1"
                     /gene_synonym="RGD1311310"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggggtgtg gttcccggcg aggggcggag ctggggatgg cgtccgcggc ggctcggcgg
       61 ctggcctggc tatcagtccg acctggggct ctctggaccg ggccgagggg gaggagaagt
      121 ggcgatgtct acaccgtacc gggcagctca ggtctcagcc aggtaccgtc gaggtcagtc
      181 atcgtcactc gcagcggcgc cattttgccc aagccggtga aaatgtcctt cggtcttctc
      241 cgtgtgttct ccattgtgat cccctttctc tatgttggga cactcattag caagaacttc
      301 gcggctctac ttgaggagca tgacattttt gtcccagagg acgatgacga tgacgattaa
      361 cagggcacag ggagtgtagg aggaagcacg gatgaatgga gtggtggcat gctcagctcc
      421 ttccgtcggc agaagggtca aggaaagccc tcagcctcac ctctcatggt ttgtgacaac
      481 agcccagaat cctgtgctct gggaggttcc ctcacgctgt ctacagagca ctggaagtaa
      541 caagcaagca aattatgagt atataataaa tgagtcatgg atgatgaaa
//
