LOCUS       NM_001037185            4241 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus structural maintenance of chromosomes 4 (Smc4),
            mRNA.
ACCESSION   NM_001037185 XM_215573
VERSION     NM_001037185.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4241)
  AUTHORS   Pan,X., Papasani,M., Hao,Y., Calamito,M., Wei,F., Quinn Iii,W.J.,
            Basu,A., Wang,J., Hodawadekar,S., Zaprazna,K., Liu,H., Shi,Y.,
            Allman,D., Cancro,M. and Atchison,M.L.
  TITLE     YY1 controls Igkappa repertoire and B-cell development, and
            localizes with condensin on the Igkappa locus
  JOURNAL   EMBO J 32 (8), 1168-1182 (2013)
   PUBMED   23531880
REFERENCE   2  (bases 1 to 4241)
  AUTHORS   Lee,J., Ogushi,S., Saitou,M. and Hirano,T.
  TITLE     Condensins I and II are essential for construction of bivalent
            chromosomes in mouse oocytes
  JOURNAL   Mol Biol Cell 22 (18), 3465-3477 (2011)
   PUBMED   21795393
REFERENCE   3  (bases 1 to 4241)
  AUTHORS   Griese,J.J., Witte,G. and Hopfner,K.P.
  TITLE     Structure and DNA binding activity of the mouse condensin hinge
            domain highlight common and diverse features of SMC proteins
  JOURNAL   Nucleic Acids Res 38 (10), 3454-3465 (2010)
   PUBMED   20139420
REFERENCE   4  (bases 1 to 4241)
  AUTHORS   Kimura,K., Cuvier,O. and Hirano,T.
  TITLE     Chromosome condensation by a human condensin complex in Xenopus egg
            extracts
  JOURNAL   J Biol Chem 276 (8), 5417-5420 (2001)
   PUBMED   11136719
REFERENCE   5  (bases 1 to 4241)
  AUTHORS   Schmiesing,J.A., Ball,A.R. Jr., Gregson,H.C., Alderton,J.M.,
            Zhou,S. and Yokomori,K.
  TITLE     Identification of two distinct human SMC protein complexes involved
            in mitotic chromosome dynamics
  JOURNAL   Proc Natl Acad Sci U S A 95 (22), 12906-12911 (1998)
   PUBMED   9789013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Aug 28, 2008 this sequence version replaced NM_001037185.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.2979.1,
                                           SRR26360181.3255407.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               JAXUCZ010000002.1  155550262-155550575
            315-452             JAXUCZ010000002.1  155551497-155551634
            453-631             JAXUCZ010000002.1  155552613-155552791
            632-823             JAXUCZ010000002.1  155553379-155553570
            824-1000            JAXUCZ010000002.1  155554913-155555089
            1001-1165           JAXUCZ010000002.1  155561352-155561516
            1166-1293           JAXUCZ010000002.1  155561893-155562020
            1294-1434           JAXUCZ010000002.1  155563318-155563458
            1435-1585           JAXUCZ010000002.1  155564066-155564216
            1586-1750           JAXUCZ010000002.1  155565996-155566160
            1751-1984           JAXUCZ010000002.1  155567117-155567350
            1985-2170           JAXUCZ010000002.1  155568827-155569012
            2171-2332           JAXUCZ010000002.1  155570210-155570371
            2333-2558           JAXUCZ010000002.1  155571843-155572068
            2559-2638           JAXUCZ010000002.1  155572163-155572242
            2639-2791           JAXUCZ010000002.1  155572801-155572953
            2792-2918           JAXUCZ010000002.1  155573855-155573981
            2919-3108           JAXUCZ010000002.1  155574545-155574734
            3109-3253           JAXUCZ010000002.1  155575469-155575613
            3254-3427           JAXUCZ010000002.1  155575824-155575997
            3428-3610           JAXUCZ010000002.1  155576642-155576824
            3611-3843           JAXUCZ010000002.1  155576923-155577155
            3844-4027           JAXUCZ010000002.1  155577729-155577912
            4028-4241           JAXUCZ010000002.1  155578482-155578695
FEATURES             Location/Qualifiers
     source          1..4241
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q32"
     gene            1..4241
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /note="structural maintenance of chromosomes 4"
                     /db_xref="GeneID:295107"
                     /db_xref="RGD:1306680"
     exon            1..314
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            315..452
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             320..4180
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /note="SMC4 structural maintenance of chromosomes 4-like
                     1"
                     /codon_start=1
                     /product="structural maintenance of chromosomes protein 4"
                     /protein_id="NP_001032262.2"
                     /db_xref="GeneID:295107"
                     /db_xref="RGD:1306680"
                     /translation="MRRKGTKPSTACHQEEGPPPSEDGALSEGEKEQPDCEVDSAAAA
                     ETPGEELDSRSLEEILNSIPPPPPPAMASEAGAPRLMITHIVNQNFKSYAGEKILGPF
                     HKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHTDIQSCTVEV
                     HFQKIIDKEGDDYDVLPNSNFYVSRTAYRDNTSVYHISGKKRTFKDVGNLLRSHGIDL
                     DHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILN
                     EHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFKKKNHICQYYIYDLQNRIAE
                     MKTQKEKIHEDTKEITEKSNVLSNEMKAKNSAVKDIEKKLNKVTKFIEQNKEKFTQLD
                     LEDVQVREKLKHATSKAKKLEKQLQKDKEKVEELKSIPAKSKNVINETTTRNNSLEKE
                     REKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYL
                     SRHNTAVSQLSKAKDALITASETLKERKAAIKDINTKLPQAQQELKEKEKELQKLTQE
                     EINLKSLVHDLFQKVEEAKSSLATNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAID
                     EKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGVATFIGLDKMAVWAQKMNKI
                     QTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTLQG
                     QIIEQSGTMTGGGSKVMRGRMGSSVVDEISVEEVNKMECQLERHSKQAAQVQEQKVQH
                     EEAIVKLKQSEREMRNTLEKFTASIQGLSEQEEYLCVQIKELEANVLTTAPDKKQQKL
                     LEENVNVFKKEYDAVAEKAGKVEAEIKRLHDTIIDINNRKLKAQQNKLDTINKQLDEC
                     ASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDNAEEVIK
                     NTKDAEKSLPEIQKEHRALLQELKVIQDNEHALQKDALSIKLKLEQIDGHISEHNSKI
                     KYWQKEISKIKLHPVEDNPVETVSVLSQEDLEAIKSPDSITNQIALLEAQCREMKPNL
                     GAIAEYKKKEELYLQRVGELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKE
                     NYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFA
                     LHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIG
                     IYKTYNITKSVAVNPKEIASKGLC"
     exon            453..631
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            632..823
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1000
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1165
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1293
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1434
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1585
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1750
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1984
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2170
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2332
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2558
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2638
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2639..2791
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2792..2918
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2919..3108
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            3109..3253
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            3254..3427
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            3428..3610
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            3611..3843
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            3844..4027
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
     exon            4028..4241
                     /gene="Smc4"
                     /gene_synonym="Smc4l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaccataga aaagacgtag tatccctcct tgctctccct tcccagtcgg aacttccccc
       61 tcgcgccaca gtcccgggta gagcccgcgc atgcgctcga acggcccgaa gatggcggtg
      121 ggaatcgccg cacttttttt caaattcgcg ggtcccagaa accattgcgc gcatttgtaa
      181 cgaatttccg ttcgagtttg gattttaggc gccattttcg agtgaagggc ccggagccga
      241 aacaccggta ggagcgaggc gggggtcggc agtcccacgg tttcagccct gctcggagtg
      301 gacctgccga caagccacca tgcggcgtaa gggcaccaag ccctccactg cctgccacca
      361 ggaagaaggg ccgccgccct ccgaggacgg tgccctcagc gaaggggaga aggagcaacc
      421 ggactgcgaa gtggacagcg ctgcagctgc agagactcca ggtgaggagc ttgatagcag
      481 aagtttagaa gagattttga atagtatccc tccaccccca cctccagcaa tggccagtga
      541 agctggagct cctcggctta tgataactca tattgtaaac caaaacttca agtcctatgc
      601 tggagagaaa attctgggac ctttccataa gcgtttttcc tgtattattg gaccaaatgg
      661 cagtggaaaa tccaatgtta ttgattccat gctttttgtg tttggctatc gagcacaaaa
      721 aataaggtct aaaaagctgt cagtactgat acataattct gatgagcaca cggatattca
      781 gagttgtact gtagaagttc attttcaaaa gataattgat aaggaagggg atgattatga
      841 cgtccttcct aacagcaact tctatgtatc tagaacagcc tacagagata acacttctgt
      901 ctatcatata agtgggaaga agaggacatt taaagatgtt ggaaatcttc ttagaagcca
      961 tgggattgac ttagaccata atcgattttt aatcttgcag ggtgaagttg aacagattgc
     1021 tatgatgaaa ccaaaaggcc agactgaaca tgatgaaggt atgcttgagt atttagaaga
     1081 tataattggc tgtggacggc taaatgaacc tattaaagtc ttgtgtcgaa gagttgaaat
     1141 attaaatgaa cacagaggag aaaagttaaa cagagtaaaa atggtagaaa aggagaagga
     1201 tgcactagaa ggagagaaaa acatagccat tgagttcctt accctggaaa atgaaatatt
     1261 taagaagaag aatcatatct gtcagtacta catctatgat ctacaaaata gaattgctga
     1321 aatgaagact caaaaggaaa aaattcatga agacactaaa gaaatcactg agaagagcaa
     1381 tgtgctttcc aatgaaatga aagctaagaa ttcagctgta aaggatatag aaaagaagct
     1441 caataaagtt acaaaattta ttgaacaaaa taaagaaaaa tttacacagc tagatttgga
     1501 agatgttcaa gttagggaaa aattaaaaca tgctacaagt aaagccaaaa aactggagaa
     1561 acaacttcaa aaagataaag aaaaggttga agagctgaaa agtatacctg ccaagagtaa
     1621 gaatgtcata aatgagacaa caactaggaa caattctctt gagaaagaaa gagagaaaga
     1681 agaaaaaaaa ttaaaagagg ttatggacag ccttaaacag gaaacacagg ggctccagaa
     1741 agaaaaggag attcaagaaa aggaacttat gggctttaac aagtcagtaa atgaagcacg
     1801 ttcaaagatg gaagtcgctc agtcagaact tgatatctat ctcagtcgac ataacacagc
     1861 agtgtctcaa ttaagtaagg cgaaggacgc gttaatcaca gcttctgaga ctctcaagga
     1921 aaggaaagct gcaatcaagg acataaacac aaagctccct caggctcaac aagaattaaa
     1981 ggagaaagaa aaagaacttc agaaactgac acaagaagaa ataaacttga aaagtttggt
     2041 tcatgatctt ttccaaaaag ttgaagaagc aaagagttcc ttagcaacaa atcgaagtag
     2101 aggaaaagta cttgatgcaa taattcaaga aaaaaagtca ggcaggatcc caggaatata
     2161 tggaagattg ggagacttag gagctattga tgaaaaatat gacattgcta tttcatcctg
     2221 ttgccatgca ttagactaca ttgttgttga ttctattgat acagcccaag aatgtgtaaa
     2281 cttccttaaa aaacataata ttggagttgc aacttttata ggtttggata agatggcagt
     2341 gtgggcccaa aaaatgaaca aaattcaaac tcctgaaaat actcctcggt tatttgattt
     2401 ggttaaagta aaaaatgagg aaatccgcca agctttttac tttgctttac gagatacctt
     2461 ggtggctaac aatttggatc aagctacaag agtagcatat caaagagata gacgatggag
     2521 agtagtaacg ctacagggcc aaatcataga acagtcgggt acaatgactg gtggcggaag
     2581 caaagtgatg agaggaagaa tgggttcttc agttgttgat gaaatctctg tagaagaggt
     2641 aaataagatg gaatgccagt tggaaaggca ttctaaacaa gcagcacaag tccaggaaca
     2701 gaaagtacaa catgaagaag ccatagttaa gttaaagcag agcgaacgag aaatgagaaa
     2761 tacactagaa aagttcactg caagcatcca gggtttatca gaacaagaag agtatttgtg
     2821 tgtacaaatt aaagaactag aagctaatgt gcttactaca gcccctgata aaaagcagca
     2881 gaaactgctt gaagaaaatg tcaatgtttt caaaaaagaa tatgatgctg tggctgagaa
     2941 agctggtaag gttgaagctg agattaaacg gctacatgat accatcatag atatcaacaa
     3001 tcgaaaactc aaagcccaac aaaacaaact tgacacaata aataagcagc tggatgaatg
     3061 tgcttctgct attaccaaag cccaagtggc gatcaagact gctgacagaa atcttaaaaa
     3121 ggcacaggat tctgtttgcc gtacagagaa agaaataaaa gacactgaaa aggaaataaa
     3181 tgacttaaaa acagaactaa aaaatattga agacaatgcc gaagaagtca taaaaaatac
     3241 aaaagatgca gagaagtcct taccagaaat ccagaaagaa catcgtgctc tccttcagga
     3301 gctaaaagtt attcaagata atgagcatgc gctccagaaa gatgcactta gtattaagtt
     3361 gaaacttgag cagatagatg gccacatttc tgaacataac tcaaaaataa aatactggca
     3421 aaaagagatt tcaaaaataa aattacatcc tgtcgaagat aaccctgttg agacagtatc
     3481 agtgctaagc caagaggatc ttgaggcaat caagagtcca gattctataa caaatcaaat
     3541 tgcacttttg gaagctcagt gtcgtgaaat gaaaccaaac cttggtgcca ttgctgagta
     3601 taaaaaaaag gaagaattat atttgcaaag agtaggcgaa ctggacaaaa ttacttctga
     3661 aagagataat tttagacaag catatgaaga tcttcgaaaa caaaggctga atgaatttat
     3721 ggctggtttt tatgtaataa caaataaact aaaagaaaac taccaaatgc tcactttggg
     3781 aggggatgct gaactggagc ttgtggatag tttagatcct ttttctgaag gaatcatgtt
     3841 cagtgttcga ccacctaaga aaagttggaa gaagatcttt aacctttcag gaggcgagaa
     3901 aacccttagc tcattggcct tggtgtttgc ccttcaccac tacaaaccca ctcccctgta
     3961 cttcatggat gagattgatg ccgctctgga ttttaaaaac gtgtctattg ttgcattcta
     4021 tatatacgag caaacaaaaa atgcacagtt cataataatc tctcttcgaa ataatatgtt
     4081 tgagatttca gatagactta ttggcatcta taaaacatat aatattacaa aaagtgttgc
     4141 agtgaaccca aaagaaattg catctaaagg actctgttga aattgttcat actgaaaatt
     4201 ttcaaataag ttgtatataa aataaatttt tctaaaacgt a
//
