LOCUS       NM_001415835            1711 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SWI/SNF related BAF chromatin remodeling complex
            subunit D3 (Smarcd3), transcript variant 2, mRNA.
ACCESSION   NM_001415835 XM_006235889
VERSION     NM_001415835.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Chen,Q., Chen,L., Jian,J., Li,J. and Zhang,X.
  TITLE     The mechanism behind BAF60c in myocardial metabolism in rats with
            heart failure is through the PGC1alpha-PPARalpha-mTOR signaling
            pathway
  JOURNAL   Biochem Cell Biol 100 (2), 93-103 (2022)
   PUBMED   33245682
  REMARK    GeneRIF: The mechanism behind BAF60c in myocardial metabolism in
            rats with heart failure is through the PGC1alpha-PPARalpha-mTOR
            signaling pathway.
REFERENCE   2  (bases 1 to 1711)
  AUTHORS   Alpsoy,A. and Dykhuizen,E.C.
  TITLE     Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its
            paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes
  JOURNAL   J Biol Chem 293 (11), 3892-3903 (2018)
   PUBMED   29374058
REFERENCE   3  (bases 1 to 1711)
  AUTHORS   Singh,A.P. and Archer,T.K.
  TITLE     Analysis of the SWI/SNF chromatin-remodeling complex during early
            heart development and BAF250a repression cardiac gene transcription
            during P19 cell differentiation
  JOURNAL   Nucleic Acids Res 42 (5), 2958-2975 (2014)
   PUBMED   24335282
REFERENCE   4  (bases 1 to 1711)
  AUTHORS   Mehrotra,A., Joe,B. and de la Serna,I.L.
  TITLE     SWI/SNF chromatin remodeling enzymes are associated with cardiac
            hypertrophy in a genetic rat model of hypertension
  JOURNAL   J Cell Physiol 228 (12), 2337-2342 (2013)
   PUBMED   23702776
REFERENCE   5  (bases 1 to 1711)
  AUTHORS   Staahl,B.T., Tang,J., Wu,W., Sun,A., Gitler,A.D., Yoo,A.S. and
            Crabtree,G.R.
  TITLE     Kinetic analysis of npBAF to nBAF switching reveals exchange of
            SS18 with CREST and integration with neural developmental pathways
  JOURNAL   J Neurosci 33 (25), 10348-10361 (2013)
   PUBMED   23785148
REFERENCE   6  (bases 1 to 1711)
  AUTHORS   Lickert,H., Takeuchi,J.K., Von Both,I., Walls,J.R., McAuliffe,F.,
            Adamson,S.L., Henkelman,R.M., Wrana,J.L., Rossant,J. and
            Bruneau,B.G.
  TITLE     Baf60c is essential for function of BAF chromatin remodelling
            complexes in heart development
  JOURNAL   Nature 432 (7013), 107-112 (2004)
   PUBMED   15525990
REFERENCE   7  (bases 1 to 1711)
  AUTHORS   Debril,M.B., Gelman,L., Fayard,E., Annicotte,J.S., Rocchi,S. and
            Auwerx,J.
  TITLE     Transcription factors and nuclear receptors interact with the
            SWI/SNF complex through the BAF60c subunit
  JOURNAL   J Biol Chem 279 (16), 16677-16686 (2004)
   PUBMED   14701856
REFERENCE   8  (bases 1 to 1711)
  AUTHORS   Otsuki,T., Furukawa,Y., Ikeda,K., Endo,H., Yamashita,T.,
            Shinohara,A., Iwamatsu,A., Ozawa,K. and Liu,J.M.
  TITLE     Fanconi anemia protein, FANCA, associates with BRG1, a component of
            the human SWI/SNF complex
  JOURNAL   Hum Mol Genet 10 (23), 2651-2660 (2001)
   PUBMED   11726552
REFERENCE   9  (bases 1 to 1711)
  AUTHORS   Wang,W., Cote,J., Xue,Y., Zhou,S., Khavari,P.A., Biggar,S.R.,
            Muchardt,C., Kalpana,G.V., Goff,S.P., Yaniv,M., Workman,J.L. and
            Crabtree,G.R.
  TITLE     Purification and biochemical heterogeneity of the mammalian SWI-SNF
            complex
  JOURNAL   EMBO J 15 (19), 5370-5382 (1996)
   PUBMED   8895581
REFERENCE   10 (bases 1 to 1711)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 3, 2023 this sequence version replaced XM_006235889.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.15109.1,
                                           SRR26643296.12339.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               JAXUCZ010000004.1  11463276-11463484
            210-421             JAXUCZ010000004.1  11466411-11466622
            422-464             JAXUCZ010000004.1  11468396-11468438
            465-587             JAXUCZ010000004.1  11469167-11469289
            588-710             JAXUCZ010000004.1  11469412-11469534
            711-806             JAXUCZ010000004.1  11469772-11469867
            807-908             JAXUCZ010000004.1  11470014-11470115
            909-1070            JAXUCZ010000004.1  11470267-11470428
            1071-1168           JAXUCZ010000004.1  11471347-11471444
            1169-1304           JAXUCZ010000004.1  11471578-11471713
            1305-1427           JAXUCZ010000004.1  11472015-11472137
            1428-1529           JAXUCZ010000004.1  11472259-11472360
            1530-1711           JAXUCZ010000004.1  11472600-11472781
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q11"
     gene            1..1711
                     /gene="Smarcd3"
                     /note="SWI/SNF related BAF chromatin remodeling complex
                     subunit D3"
                     /db_xref="GeneID:296732"
                     /db_xref="RGD:1311869"
     exon            1..209
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1583
                     /gene="Smarcd3"
                     /note="isoform 2 is encoded by transcript variant 2;
                     SWI/SNF-related matrix-associated actin-dependent
                     regulator of chromatin subfamily D member 3; SWI/SNF
                     related, matrix associated, actin dependent regulator of
                     chromatin, subfamily d, member 3"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily D member
                     3 isoform 2"
                     /protein_id="NP_001402764.1"
                     /db_xref="GeneID:296732"
                     /db_xref="RGD:1311869"
                     /translation="MAADEVAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMG
                     PPGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQGQGQPVPTAPARSRSAKRRK
                     MADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLY
                     ISNTFNPAKPDAEDSDGSIASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYG
                     PDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLH
                     TQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTGLLL
                     PPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKI
                     HETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFY
                     HQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT"
     exon            210..421
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            422..464
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            465..587
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            588..710
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            711..806
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            807..908
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1070
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1168
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1304
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1427
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1529
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1711
                     /gene="Smarcd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actccgctcg agtagaagtg tgagagagcc cagcaggact cagaggggag agttggagga
       61 aaaaaaaggc agaaaaggga aagaaagagg aagagagaga gagagtgaga ggagccgctg
      121 agcccacccc gatggccgcg gacgaagttg ccggaggggc gcgcaaagcc acgaaaagca
      181 aactttttga gtttctggtc catggggtgc gccccgggat gccgtctgga gcccgaatgc
      241 cccaccaggg ggcgcccatg ggccccccgg gctccccgta catgggcagc cccgcggtac
      301 gacccggcct ggcccccgcg ggcatggagc ccgcccgcaa gcgagcagcg cccccgcccg
      361 ggcagagcca ggcacaaggc cagggccagc cggtgcccac cgccccagcg cggagccgca
      421 gtgccaagag gaggaagatg gctgacaaaa tcctccctca aaggattcgg gagctggtcc
      481 ctgagtccca ggcttacatg gacctcctag catttgagag gaaactggat caaaccatta
      541 tgcggaagcg ggtggacatc caggaggccc tgaagaggcc catgaagcaa aagcgaaagc
      601 tgcgccttta tatctccaat acttttaacc ccgcgaagcc cgatgccgaa gattctgatg
      661 gcagcattgc ctcctgggag ctgcgggtgg aggggaagct cttggatgat cccagtaagc
      721 agaagaggaa gttttcttcc ttcttcaaga gtttggtcat tgagttggac aaagaccttt
      781 atggcccaga caaccacctt gttgagtggc accggacacc cacaacccag gagacagatg
      841 ggttccaagt gaagagacca ggggacttga gtgtgcgctg taccctgctc ctgatgctgg
      901 actatcagcc tccccagttc aaactggacc cccgcttggc ccggctgctg gggttgcata
      961 cgcagagccg ctcagccatt gtccaggcac tgtggcagta cgtgaagacc aacaggctac
     1021 aggactccca tgacaaggaa tacatcaatg gagacaagta tttccagcag atttttgact
     1081 gtccccgcct gaagttttct gagattcccc agcgtctcac aggcctgctg cttcctcctg
     1141 accccattgt gatcaaccat gtcatcagcg tggacccatc agaccagaag aagaccgcgt
     1201 gctatgacat tgatgtggag gtggaggaac cactgaaggg gcagatgagc agctttctcc
     1261 tgtccaccgc caaccagcag gagatcagtg ctctggacag taagatccat gagaccattg
     1321 agtccataaa tcagctcaag atccagaggg acttcatgct aagtttctcc agagacccca
     1381 aaggctacgt ccaagacctg ctccgctccc agagccgtga tctcaaggtg atgacagatg
     1441 tggccggtaa ccccgaggaa gagcgccggg ctgagttcta ccaccagccc tggtcccagg
     1501 aagctgtcag ccgctacttc tactgtaaga tccagcagcg caggcaggag ctggagcagt
     1561 cactagttgt gcgcaacacc taggagcctg tgaacacgca tcactgtgga ccagcctcgc
     1621 tgcccagcat ggaccctggg ctctggactc cctctcccgt gctgtgctgg ggttggggag
     1681 ggctggatta aaggtcactc atcagacagc a
//
