LOCUS       NM_031983               2593 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SWI/SNF related BAF chromatin remodeling complex
            subunit D2 (Smarcd2), mRNA.
ACCESSION   NM_031983
VERSION     NM_031983.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2593)
  AUTHORS   Singh,A.P. and Archer,T.K.
  TITLE     Analysis of the SWI/SNF chromatin-remodeling complex during early
            heart development and BAF250a repression cardiac gene transcription
            during P19 cell differentiation
  JOURNAL   Nucleic Acids Res 42 (5), 2958-2975 (2014)
   PUBMED   24335282
REFERENCE   2  (bases 1 to 2593)
  AUTHORS   Shain,A.H. and Pollack,J.R.
  TITLE     The spectrum of SWI/SNF mutations, ubiquitous in human cancers
  JOURNAL   PLoS One 8 (1), e55119 (2013)
   PUBMED   23355908
REFERENCE   3  (bases 1 to 2593)
  AUTHORS   Hargreaves,D.C. and Crabtree,G.R.
  TITLE     ATP-dependent chromatin remodeling: genetics, genomics and
            mechanisms
  JOURNAL   Cell Res 21 (3), 396-420 (2011)
   PUBMED   21358755
  REMARK    Review article
REFERENCE   4  (bases 1 to 2593)
  AUTHORS   Mahajan,M.C., Narlikar,G.J., Boyapaty,G., Kingston,R.E. and
            Weissman,S.M.
  TITLE     Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF
            form a chromatin remodeling complex at the beta-globin locus
            control region
  JOURNAL   Proc Natl Acad Sci U S A 102 (42), 15012-15017 (2005)
   PUBMED   16217013
REFERENCE   5  (bases 1 to 2593)
  AUTHORS   Olave,I., Wang,W., Xue,Y., Kuo,A. and Crabtree,G.R.
  TITLE     Identification of a polymorphic, neuron-specific chromatin
            remodeling complex
  JOURNAL   Genes Dev 16 (19), 2509-2517 (2002)
   PUBMED   12368262
REFERENCE   6  (bases 1 to 2593)
  AUTHORS   Otsuki,T., Furukawa,Y., Ikeda,K., Endo,H., Yamashita,T.,
            Shinohara,A., Iwamatsu,A., Ozawa,K. and Liu,J.M.
  TITLE     Fanconi anemia protein, FANCA, associates with BRG1, a component of
            the human SWI/SNF complex
  JOURNAL   Hum Mol Genet 10 (23), 2651-2660 (2001)
   PUBMED   11726552
REFERENCE   7  (bases 1 to 2593)
  AUTHORS   Nomoto,K., Nakazato,S., Kazahari,K. and Ono,M.
  TITLE     Gene structure of rat BAF60b, a component of mammalian SW1/SNF
            complexes, and its physical linkage to the growth hormone gene and
            transcription factor SUG/proteasome p45 gene
  JOURNAL   Gene 202 (1-2), 157-165 (1997)
   PUBMED   9427560
REFERENCE   8  (bases 1 to 2593)
  AUTHORS   Wang,W., Cote,J., Xue,Y., Zhou,S., Khavari,P.A., Biggar,S.R.,
            Muchardt,C., Kalpana,G.V., Goff,S.P., Yaniv,M., Workman,J.L. and
            Crabtree,G.R.
  TITLE     Purification and biochemical heterogeneity of the mammalian SWI-SNF
            complex
  JOURNAL   EMBO J 15 (19), 5370-5382 (1996)
   PUBMED   8895581
REFERENCE   9  (bases 1 to 2593)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC062063.1.
            
            On Dec 20, 2003 this sequence version replaced NM_031983.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062063.1, AB003504.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2593
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..2593
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /note="SWI/SNF related BAF chromatin remodeling complex
                     subunit D2"
                     /db_xref="GeneID:83833"
                     /db_xref="RGD:69289"
     exon            1..301
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..1681
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /note="BRG1-associated factor 60B; 60 kDa
                     BRG-1/Brm-associated factor subunit B; SWI/SNF related,
                     matrix associated, actin dependent regulator of chromatin,
                     subfamily d, member 2"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily D member
                     2"
                     /protein_id="NP_114189.1"
                     /db_xref="GeneID:83833"
                     /db_xref="RGD:69289"
                     /translation="MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPNPALRG
                     PGPSGGMGVPGAAAFRPMGPAGPAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAP
                     LRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYM
                     DLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNSGTAGTP
                     GGTPAADKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHR
                     MPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQA
                     LWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHV
                     ISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQL
                     KTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVG
                     RHIFAKVQQRRQELEQVLGIRLT"
     exon            302..486
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            487..529
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            530..652
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            653..808
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            809..904
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1006
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1168
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1266
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1402
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1525
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1627
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..2575
                     /gene="Smarcd2"
                     /gene_synonym="BAF60b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccggatcgc ggaacagagc tcgcggagcg gactcaacac ggagacgaga ggccggatcg
       61 ctgcaccgcg ggacgggaca gagtgatgtc gggccgtggc gcgggcgggt tcccgctgcc
      121 cccgctgagc cccggcggcg gcgccgttgc cgcggccctc ggtgcgccgc ctccgcctgc
      181 gggacccgga atgctgccca acccggcgct caggggcccg gggccttctg gaggcatggg
      241 ggtaccgggg gccgctgcct tccgccccat gggccccgcg ggccccgcgg cgcagtacca
      301 gcgacctggc atgtccccag gaagtaggat gcccatggct ggcttgcagg tgggacctcc
      361 ggctggttcc ccatttggca cagctgctcc acttcgacct ggcatgccac ctaccatgat
      421 ggatccattc cgaaaacgcc tgcttgtgcc tcaggcccag cccccgatgc ctgcccagcg
      481 ccgagggtta aagaggagga agatggcaga taaggttcta cctcagcgaa tccgggagct
      541 tgtcccagag tctcaggcat acatggatct tttagctttc gagaggaagc tggaccagac
      601 catcgctcgc aagcggatgg agatccaaga ggccatcaag aagcctctga cgcaaaagcg
      661 aaaacttcgg atctatattt ccaatacatt cagtcccagc aaggcagatg gtgataattc
      721 aggaactgca gggacccctg ggggaacccc agcagcagac aaggtggcct cctgggagct
      781 tcgagtagag ggaaaacttc tggatgatcc tagcaaacag aagaggaagt tctcctcatt
      841 ctttaagagc cttgttatcg agttggacaa ggagctgtat gggcctgaca accatctggt
      901 ggagtggcat cggatgccca ccactcagga aacagatggc tttcaggtga aacggccagg
      961 agatctcaat gtcaagtgca cccttctgct catgctggat catcagccac ctcagtataa
     1021 actggacccc cgcctggcga ggttgctggg agtgcacaca cagacgagag ctgccatcat
     1081 gcaggcgctg tggctttaca tcaaacacaa ccagctgcag gatgggcatg agcgggagta
     1141 catcaactgc aaccgctact tccgccagat cttcagctgt ggccggctcc gtttctccga
     1201 gatccccatg aagctggctg ggctgctgca gcatccagac cccattgtta ttaaccatgt
     1261 cattagcgtg gaccctaatg accagaagaa gacagcctgt tatgacatcg acgtagaggt
     1321 tgatgacccc ctgaaggccc agatgagtaa cttcctggcc tctaccacca accagcagga
     1381 gattgcctct cttgatgtca agatccatga gaccattgag tccatcaacc agctgaagac
     1441 ccagagggac ttcatgctca gcttcagcac cgagccccag gacttcatcc aggaatggct
     1501 ccgctcccaa cgccgagacc tcaagatcat cacagatgtg attggaaacc ctgaggagga
     1561 gagacgagct gctttctacc accagccctg ggctcaggaa gcagttggga ggcacatctt
     1621 tgccaaggtg cagcagcgaa ggcaggaact ggaacaggtg ctgggaattc gcctgaccta
     1681 actgctcagg gattgcttcc ttccttccct gccctggaac ctggcaggag accacctcgt
     1741 ggtcatggct ggggctgcag acatacagga tggagtgagg tgtatctcct gtcaccctct
     1801 actccccagc tttagtttca taagtgtagt tttagagtcc tcactgcttg gtccccaaag
     1861 ccttattact taccttttag cgctggcttt aattaggttt gcaacgtgct gcctcagccc
     1921 cctgcaggca ggcccaggta ggactgctgg aggctgtgct tttaactttg taacagacat
     1981 ttccgaacca aaggctgctg ggtttgcatg tttacaggct ccaccctagg gccagtgtca
     2041 gagctggctt tggggagctg ggcaaggaag aggaggccca gcccagactc ttcctggcct
     2101 ttctcaacca aagttctttg ccattcctac aagcccagcc ttgctgctgg ttgtccttct
     2161 ctttgggtat ttgcactatt tggggagcag gtttttctat gtgggagcca cttttttgta
     2221 cagaggtaac ggggtttttc agggagccca cttggtgcct ccttccttat tttcttttct
     2281 taatctatgc aagcggctgc agccgccatc atctcctgga tgccatgggg ctgcccaccc
     2341 atagctgatt gagcaggggg aggtggaacc tcctgagggt gggaatgtgc cagctctcta
     2401 acccagctaa agaaggggcg tacgtgtgtg cgtgcactct gcaggggaag gggaaagctg
     2461 gagatctgtt gttacctttt gcagttggtc ttaaagaggg tgggcctaag gcttggcaaa
     2521 tgccacttct ggcaaacttg gaaaattcca aataaatctt tttgtttatt ggtggaaaaa
     2581 aaaaaaaaaa aaa
//
