LOCUS       NM_001025728            1628 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SWI/SNF related BAF chromatin remodeling complex
            subunit B1 (Smarcb1), mRNA.
ACCESSION   NM_001025728 XM_342119
VERSION     NM_001025728.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Kakkar,A., Antony,V.M., Pramanik,R., Sakthivel,P., Singh,C.A. and
            Jain,D.
  TITLE     SMARCB1 (INI1)-deficient sinonasal carcinoma: a series of 13 cases
            with assessment of histologic patterns
  JOURNAL   Hum Pathol 83, 59-67 (2019)
   PUBMED   30120966
REFERENCE   2  (bases 1 to 1628)
  AUTHORS   Kuwahara,Y., Kennedy,L.M., Karnezis,A.N., Mora-Blanco,E.L.,
            Rogers,A.B., Fletcher,C.D., Huntsman,D.G., Roberts,C.W.M.,
            Rathmell,W.K. and Weissman,B.E.
  TITLE     High Frequency of Ovarian Cyst Development in Vhl2B/+;Snf5+/- Mice
  JOURNAL   Am J Pathol 188 (7), 1510-1516 (2018)
   PUBMED   29684361
REFERENCE   3  (bases 1 to 1628)
  AUTHORS   Louvrier,C., Pasmant,E., Briand-Suleau,A., Cohen,J., Nitschke,P.,
            Nectoux,J., Orhant,L., Zordan,C., Goizet,C., Goutagny,S.,
            Lallemand,D., Vidaud,M., Vidaud,D., Kalamarides,M. and Parfait,B.
  TITLE     Targeted next-generation sequencing for differential diagnosis of
            neurofibromatosis type 2, schwannomatosis, and meningiomatosis
  JOURNAL   Neuro Oncol 20 (7), 917-929 (2018)
   PUBMED   29409008
REFERENCE   4  (bases 1 to 1628)
  AUTHORS   Wu,S., Han,N., Zheng,Y., Hu,C. and Lei,Y.
  TITLE     The role of Snf5 in the osteogenic differentiation potential during
            replicative senescence of rat mesenchymal stromal cells
  JOURNAL   Mech Ageing Dev 171, 1-6 (2018)
   PUBMED   29398003
  REMARK    GeneRIF: These findings indicate that the decreased level of Snf5
            binding to the promoter region of the Oct4 gene down-regulated the
            expression of Oct4, which may be the mechanism underlying the
            decline in osteogenic capacities in replicative senescent BMSCs.
REFERENCE   5  (bases 1 to 1628)
  AUTHORS   Sarnowska,E., Szymanski,M., Rusetska,N., Ligaj,M., Jancewicz,I.,
            Cwiek,P., Skrodzka,M., Leszczynski,M., Szarkowska,J., Chrzan,A.,
            Stachowiak,M., Steciuk,J., Maassen,A., Galek,L., Demkow,T.,
            Siedlecki,J.A. and Sarnowski,T.J.
  TITLE     Evaluation of the role of downregulation of SNF5/INI1 core subunit
            of SWI/SNF complex in clear cell renal cell carcinoma development
  JOURNAL   Am J Cancer Res 7 (11), 2275-2289 (2017)
   PUBMED   29218250
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1628)
  AUTHORS   Roberts,C.W., Galusha,S.A., McMenamin,M.E., Fletcher,C.D. and
            Orkin,S.H.
  TITLE     Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to
            malignant rhabdoid tumors in mice
  JOURNAL   Proc Natl Acad Sci U S A 97 (25), 13796-13800 (2000)
   PUBMED   11095756
REFERENCE   7  (bases 1 to 1628)
  AUTHORS   Xue,Y., Canman,J.C., Lee,C.S., Nie,Z., Yang,D., Moreno,G.T.,
            Young,M.K., Salmon,E.D. and Wang,W.
  TITLE     The human SWI/SNF-B chromatin-remodeling complex is related to
            yeast rsc and localizes at kinetochores of mitotic chromosomes
  JOURNAL   Proc Natl Acad Sci U S A 97 (24), 13015-13020 (2000)
   PUBMED   11078522
REFERENCE   8  (bases 1 to 1628)
  AUTHORS   Versteege,I., Sevenet,N., Lange,J., Rousseau-Merck,M.F., Ambros,P.,
            Handgretinger,R., Aurias,A. and Delattre,O.
  TITLE     Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
  JOURNAL   Nature 394 (6689), 203-206 (1998)
   PUBMED   9671307
REFERENCE   9  (bases 1 to 1628)
  AUTHORS   Wang,W., Cote,J., Xue,Y., Zhou,S., Khavari,P.A., Biggar,S.R.,
            Muchardt,C., Kalpana,G.V., Goff,S.P., Yaniv,M., Workman,J.L. and
            Crabtree,G.R.
  TITLE     Purification and biochemical heterogeneity of the mammalian SWI-SNF
            complex
  JOURNAL   EMBO J 15 (19), 5370-5382 (1996)
   PUBMED   8895581
REFERENCE   10 (bases 1 to 1628)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099195.1.
            
            [WARNING] On Nov 15, 2024 this sequence was replaced by
            NM_001025728.2.
            
            On Jul 22, 2005 this sequence version replaced XM_342119.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099195.1, FQ232860.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1628
                     /gene="Smarcb1"
                     /note="SWI/SNF related BAF chromatin remodeling complex
                     subunit B1"
                     /db_xref="GeneID:361825"
                     /db_xref="RGD:1308761"
     exon            1..289
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1327
                     /gene="Smarcb1"
                     /note="SWI/SNF related, matrix associated, actin dependent
                     regulator of chromatin, subfamily b, member 1"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily B member
                     1"
                     /protein_id="NP_001020899.1"
                     /db_xref="GeneID:361825"
                     /db_xref="RGD:1308761"
                     /translation="MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLY
                     KRYPSLWRRLATVEERKKIVASSHDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVS
                     ISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFD
                     DHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLD
                     LNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSE
                     KENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNT
                     GDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW"
     exon            290..401
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            402..531
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            532..669
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            670..797
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            798..964
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1155
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1287
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1604
                     /gene="Smarcb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagggagg cctgctcttc gcagagacgg cttaagaacc tagtagtgac gcgagcgcct
       61 tcccggtttg cccggctcgc cctgtccgtc cttcacctcc cggcctccgt tcctttcggt
      121 ccgacgcgcc tcggccccgc cccagcccac cggattcttt ccagctcgac cccggctgcc
      181 agtttccccc gccgccatga tgatgatggc gttgagcaag accttcgggc agaagcccgt
      241 caagtttcag ctggaggacg acggggagtt ctacatgatc ggctccgagg tgggaaacta
      301 cctgcgtatg ttccgaggtt ctctgtacaa gagatacccc tcactctggc ggcgactagc
      361 cactgtggaa gaaaggaaga aaatagtggc atcgtcacat gaccatggat acaccaccct
      421 ggccaccagc gtgacgctac tgaaagcctc agaggtggaa gagattctgg acggcaatga
      481 cgagaagtac aaggctgtgt ccatcagcac agagccccca acctacctca gggaacagaa
      541 ggccaagaga aacagccagt gggtccccac cctgcccaac agctcccacc atctggacgc
      601 tgtgccgtgc tccaccacca tcaataggaa tcgcatgggt cgggacaaga agagaacctt
      661 ccccttgtgc tttgatgacc acgacccagc tgtgatccat gagaatgcat ctcagcccga
      721 ggtactggtc cccattcggc tggacatgga gatcgacggg cagaagctgc gagacgcttt
      781 tacctggaac atgaatgaga agctaatgac cccagagatg ttttcagaaa tactttgtga
      841 tgacctggac ttgaatccac tgacttttgt gccagctatt gcctctgcca ttcgacagca
      901 gatcgagtcc taccccacag acagcatcct ggaggaccaa tctgaccagc gtgtcatcat
      961 caagctgaac atccatgtgg ggaacatctc cctggtggac cagtttgaat gggacatgtc
     1021 agagaaagag aactccccag agaagtttgc cctgaagctg tgctcagagc tgggcttggg
     1081 cggggagttt gtcaccacca ttgcgtacag catccgagga cagctgagct ggcaccagaa
     1141 gacctatgcc ttcagtgaga acccacttcc cacagtggag attgccatcc gaaatactgg
     1201 agatgctgac cagtggtgcc ccctgctgga gacactgacg gatgctgaga tggagaagaa
     1261 gatccgggat caagacagga acacaaggcg aatgaggcgt cttgccaaca ctgccccagc
     1321 ctggtgatga agccatccat gctcgacttc tactgagcat ctcaaaagac tgcctttcct
     1381 tcctctgtgg taaatagaaa ggcaacggga cagctggtgc catcctgagg actggggtag
     1441 gagcctcctg ggtgccctcc ttcagcacac attccactcg ctaaacccca acactgtccc
     1501 cgagtctaga gacgggaagc agcctcattt gggttgtgtg ttgtttttgt ataggagccc
     1561 caggcagggc tagtaacact tttaaataaa aggtaacatg ttcaaaaaaa aaaaaaaaaa
     1621 aaaaaaaa
//
