LOCUS       NM_001108222            3041 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SNF2 related chromatin remodeling annealing
            helicase 1 (Smarcal1), mRNA.
ACCESSION   NM_001108222 XM_001055492 XM_237241
VERSION     NM_001108222.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3041)
  AUTHORS   Keka,I.S., Mohiuddin, Maede,Y., Rahman,M.M., Sakuma,T., Honma,M.,
            Yamamoto,T., Takeda,S. and Sasanuma,H.
  TITLE     Smarcal1 promotes double-strand-break repair by nonhomologous
            end-joining
  JOURNAL   Nucleic Acids Res 43 (13), 6359-6372 (2015)
   PUBMED   26089390
REFERENCE   2  (bases 1 to 3041)
  AUTHORS   Yuan,J., Ghosal,G. and Chen,J.
  TITLE     The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA
            and participates in cellular response to replication stress
  JOURNAL   Mol Cell 47 (3), 410-421 (2012)
   PUBMED   22705370
REFERENCE   3  (bases 1 to 3041)
  AUTHORS   Yusufzai,T., Kong,X., Yokomori,K. and Kadonaga,J.T.
  TITLE     The annealing helicase HARP is recruited to DNA repair sites via an
            interaction with RPA
  JOURNAL   Genes Dev 23 (20), 2400-2404 (2009)
   PUBMED   19793863
REFERENCE   4  (bases 1 to 3041)
  AUTHORS   Ciccia,A., Bredemeyer,A.L., Sowa,M.E., Terret,M.E.,
            Jallepalli,P.V., Harper,J.W. and Elledge,S.J.
  TITLE     The SIOD disorder protein SMARCAL1 is an RPA-interacting protein
            involved in replication fork restart
  JOURNAL   Genes Dev 23 (20), 2415-2425 (2009)
   PUBMED   19793862
REFERENCE   5  (bases 1 to 3041)
  AUTHORS   Yusufzai,T. and Kadonaga,J.T.
  TITLE     HARP is an ATP-driven annealing helicase
  JOURNAL   Science 322 (5902), 748-750 (2008)
   PUBMED   18974355
REFERENCE   6  (bases 1 to 3041)
  AUTHORS   Boerkoel,C.F., Takashima,H., John,J., Yan,J., Stankiewicz,P.,
            Rosenbarker,L., Andre,J.L., Bogdanovic,R., Burguet,A.,
            Cockfield,S., Cordeiro,I., Frund,S., Illies,F., Joseph,M.,
            Kaitila,I., Lama,G., Loirat,C., McLeod,D.R., Milford,D.V.,
            Petty,E.M., Rodrigo,F., Saraiva,J.M., Schmidt,B., Smith,G.C.,
            Spranger,J., Stein,A., Thiele,H., Tizard,J., Weksberg,R.,
            Lupski,J.R. and Stockton,D.W.
  TITLE     Mutant chromatin remodeling protein SMARCAL1 causes Schimke
            immuno-osseous dysplasia
  JOURNAL   Nat Genet 30 (2), 215-220 (2002)
   PUBMED   11799392
REFERENCE   7  (bases 1 to 3041)
  AUTHORS   Coleman,M.A., Eisen,J.A. and Mohrenweiser,H.W.
  TITLE     Cloning and characterization of HARP/SMARCAL1: a prokaryotic
            HepA-related SNF2 helicase protein from human and mouse
  JOURNAL   Genomics 65 (3), 274-282 (2000)
   PUBMED   10857751
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474004.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_237241.4, XM_001055492.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC168154.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3041
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..3041
                     /gene="Smarcal1"
                     /note="SNF2 related chromatin remodeling annealing
                     helicase 1"
                     /db_xref="GeneID:316477"
                     /db_xref="RGD:1306134"
     exon            1..167
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            168..931
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     CDS             226..2958
                     /gene="Smarcal1"
                     /note="hepA-related protein; sucrose nonfermenting protein
                     2-like 1; Swi/SNF related matrix associated, actin
                     dependent regulator of chromatin, subfamily a-like 1"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily A-like
                     protein 1"
                     /protein_id="NP_001101692.1"
                     /db_xref="GeneID:316477"
                     /db_xref="RGD:1306134"
                     /translation="MSLPLTEEQRKKIEENRQKALARRAEKLWAEQPQSTASGSSAAR
                     PSQCKQNSLLNLPAEPSKPEGHATISKGQNLNNSLPAAQRPHSSPCFQPSTAEEAKGL
                     WKSEGKMSAACPNPSPPEVSNQQLLGSKSSEGHPQATQDTAASCPRPFPRDPKLEAKA
                     GRPSTSGQSISDTFYALGEKTPKTDGRPAKALQTSPQKASCLRGMCLRTGDRFRVKIG
                     YNKELIEVFKSLPSRRYDSFTKTWDFSMSDYRALMKAVERLSTVSLQPLEEVDGTGGQ
                     TSLPSAPSLTFVTGRCMLISRARFEVDIGYSEVVIALFKQMESRNYDPKTRKWNFLLE
                     EHNKLIARSRELKQVQLDPLPKTLTLAFASQLEKTSLQSKADVPEADLSGVDAKLVSN
                     LMPFQREGVSFAISKRGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTW
                     EQAFLRWLPSLSPEDINVVVTGKGRLTAGLVNIVSFDLLSKLEKQLKTPFKVVIIDES
                     HFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFG
                     LRYCDAKRLPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKMVVVNPG
                     RISTRAKAALDAAAKEMTKDKTKQQQKEALLVFFNRTAEAKIPCVIEYILDLLESGRE
                     KFLVFAHHKVLLDAIAKELERKNVQHIRIDGSTPSADREDLCQQFQLSKGHTVAVLSI
                     TAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVGIHYLVAKGTADDYL
                     WPLIQEKIKVLGEAGLSETNFSEMTEATDYLYKDPKQKTIYSLFQQSFEDDGNDMEFL
                     EAAESFELGSTSGTSGNSSQELGDITDENALADSPPKKRRFEFFDNWDSFTSPF"
     exon            932..982
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1192
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1243
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1430
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1581
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1740
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1806
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1947
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2163
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2234
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2337
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2338..2520
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2621
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2718
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
     exon            2719..3041
                     /gene="Smarcal1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccattcaatg ccagccgccc gcgcagagat atgtgaagtt gcagctcttg agttttagtt
       61 cttctcacag tccatccaga aacgaaaact gcccaggcaa agctctgaaa gacactcctg
      121 ggctagggct cttctgcgaa ggtgcttcac cttaccagtc tcgccagctt ctgccaactt
      181 cccagttaaa gggtgacatt tctgcagaag cctatcctgt tagaaatgtc cttgccactt
      241 acggaggagc agaggaaaaa gattgaagag aatcggcaga aggctttggc ccgtcgagct
      301 gagaagctat gggcagaaca gccccagagt acagcttcag gctccagtgc tgccaggccg
      361 tcccagtgca agcagaactc tctcctgaat ctcccagcgg agccttcaaa gccagagggc
      421 catgctacca tttccaaggg acagaatctc aataattcac tccctgctgc tcagagacct
      481 cacagctccc cctgttttca acccagcaca gcagaggaag caaagggact atggaagagc
      541 gaaggaaaga tgtccgcagc ctgcccaaac ccaagtcccc cagaagtctc taaccaacag
      601 cttttgggta gtaaatccag tgagggtcat ccccaggcaa cccaggacac agcagcttcc
      661 tgtcctagac catttcccag ggatcccaag ttagaggcca aggcagggag gccctccacc
      721 tctggacaga gcatttcgga caccttttat gccttagggg aaaaaacacc taagacagat
      781 gggagacccg caaaggcact gcagacctca ccccaaaaag caagctgtct acggggaatg
      841 tgcttaagga caggggatcg cttccgggta aagatcggct acaacaagga gctcattgag
      901 gtgtttaagt ctctgcccag cagacgctat gattcgttta cgaagacgtg ggacttcagc
      961 atgagtgact acagagcctt gatgaaggcc gtcgagcgac tctccacggt ctcccttcag
     1021 ccattggaag aggtcgatgg cactggggga cagaccagcc tcccctcagc tccatccctt
     1081 acctttgtca cagggagatg catgctcatt tcccgagccc gcttcgaggt tgacatcggc
     1141 tattctgagg tggtgattgc cctgtttaag cagatggagt ccaggaatta cgatccgaag
     1201 accaggaagt ggaactttct cttggaagag cacaataaac taattgcaag gtcccgtgag
     1261 ctcaagcaag tccagctgga ccctctgccc aagaccttga ccctggcatt tgcatctcag
     1321 ctggagaaaa cgtctctcca atcgaaagca gatgtgccag aagctgacct ttctggagtg
     1381 gatgccaagc ttgtgtctaa cctcatgccc tttcagagag agggagttag ctttgccata
     1441 tcaaaaagag gccgcctgct acttgccgat gacatgggcc tagggaagac catccaagcc
     1501 atctgcatag cagcttttta ccgaaaggaa tggccactgc tggtggttgt gccttcctct
     1561 gtgcgcttca cctgggagca ggcctttctg cgatggcttc catcacttag cccagaggac
     1621 atcaacgtgg tggtgactgg gaagggccgc ctaacagctg gcttggtcaa cattgtcagc
     1681 tttgaccttc tgagcaagtt ggagaagcag ctaaaaaccc ctttcaaagt cgtcattatt
     1741 gatgaatcgc acttcctcaa aaacatcaag actgcccgat gccgagcagc tgtgcctatc
     1801 ctaaaggttg ccaagagggt gatcctgctg tcgggcacac ctgccatgtc gaggcctgca
     1861 gagctctaca cacagatcat tgctgtcaag ccaaccttct tccctcagtt tcatgctttc
     1921 ggactgcgct actgtgatgc caagcggctc ccttggggct gggactactc gggctcctcc
     1981 aacctgggtg agctgaagct gctgctggag gaggcagtca tgctgcggcg gctcaaatct
     2041 gatgtccttt cccagcttcc agccaagcaa cgcaagatgg tggtggtcaa ccctggtcgg
     2101 atcagcacca gggctaaggc agccctggat gcagcagcca aagaaatgac caaggacaaa
     2161 actaaacagc agcagaagga agctctcctt gtcttcttca acagaacagc agaagctaaa
     2221 atcccatgtg tcatcgaata tatcctggac cttctggaga gcgggcgaga gaagtttcta
     2281 gtgtttgcac accataaggt gcttctggat gcgattgcta aggaacttga gaggaagaat
     2341 gttcagcaca tccgcattga tggctccacg ccctctgcag accgggagga tctgtgccag
     2401 cagttccagc tgtccaaagg acatacggtg gcagtgttgt ccatcacagc cgccaacatg
     2461 ggcctcacct tctcctcggc tgatctggtg gtgtttgctg agctgttttg gaaccccggg
     2521 gtgttgatcc aggccgagga ccgcgtgcac cgcattggac agacaaactc tgtgggcatc
     2581 cactacctgg tggcaaaagg caccgcagat gactacctct ggcctctgat tcaagagaag
     2641 attaaagttc tgggggaagc tgggctttct gagaccaatt tctcagaaat gacagaagct
     2701 actgactacc tctacaagga cccaaaacag aagacgatct atagcctgtt ccagcagtcc
     2761 ttcgaagacg atgggaatga catggaattc ctggaggcag cagagtcctt tgaactagga
     2821 agtacttcag ggacctctgg aaatagctcg caggagctag gagatatcac agatgagaac
     2881 gccttggcag acagcccacc aaagaaaagg agatttgaat tctttgataa ttgggacagc
     2941 tttacctctc ccttttgaaa ggttcaaaga aagaaaagaa atgaaagcat tcaaaaaatc
     3001 atgggactca atgaaataaa atattttgtt taaaagcctg t
//
