LOCUS       NM_001107864            4795 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SNF2 related chromatin remodeling ATPase with
            DExD box 1 (Smarcad1), mRNA.
ACCESSION   NM_001107864 XM_001066395 XM_231860
VERSION     NM_001107864.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4795)
  AUTHORS   Costelloe,T., Louge,R., Tomimatsu,N., Mukherjee,B., Martini,E.,
            Khadaroo,B., Dubois,K., Wiegant,W.W., Thierry,A., Burma,S., van
            Attikum,H. and Llorente,B.
  TITLE     The yeast Fun30 and human SMARCAD1 chromatin remodellers promote
            DNA end resection
  JOURNAL   Nature 489 (7417), 581-584 (2012)
   PUBMED   22960744
REFERENCE   2  (bases 1 to 4795)
  AUTHORS   Rowbotham,S.P., Barki,L., Neves-Costa,A., Santos,F., Dean,W.,
            Hawkes,N., Choudhary,P., Will,W.R., Webster,J., Oxley,D.,
            Green,C.M., Varga-Weisz,P. and Mermoud,J.E.
  TITLE     Maintenance of silent chromatin through replication requires
            SWI/SNF-like chromatin remodeler SMARCAD1
  JOURNAL   Mol Cell 42 (3), 285-296 (2011)
   PUBMED   21549307
REFERENCE   3  (bases 1 to 4795)
  AUTHORS   Okazaki,N., Ikeda,S., Ohara,R., Shimada,K., Yanagawa,T., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     The novel protein complex with SMARCAD1/KIAA1122 binds to the
            vicinity of TSS
  JOURNAL   J Mol Biol 382 (2), 257-265 (2008)
   PUBMED   18675275
REFERENCE   4  (bases 1 to 4795)
  AUTHORS   Adra,C.N., Donato,J.L., Badovinac,R., Syed,F., Kheraj,R., Cai,H.,
            Moran,C., Kolker,M.T., Turner,H., Weremowicz,S., Shirakawa,T.,
            Morton,C.C., Schnipper,L.E. and Drews,R.
  TITLE     SMARCAD1, a novel human helicase family-defining member associated
            with genetic instability: cloning, expression, and mapping to
            4q22-q23, a band rich in breakpoints and deletion mutants involved
            in several human diseases
  JOURNAL   Genomics 69 (2), 162-173 (2000)
   PUBMED   11031099
REFERENCE   5  (bases 1 to 4795)
  AUTHORS   Schoor,M., Schuster-Gossler,K. and Gossler,A.
  TITLE     The Etl-1 gene encodes a nuclear protein differentially expressed
            during early mouse development
  JOURNAL   Dev Dyn 197 (3), 227-237 (1993)
   PUBMED   8219362
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 11, 2008 this sequence version replaced NM_001107864.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.16229.1,
                                           SRR26643429.16646.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               JAXUCZ010000004.1  95641900-95642139
            241-418             JAXUCZ010000004.1  95649654-95649831
            419-584             JAXUCZ010000004.1  95651957-95652122
            585-651             JAXUCZ010000004.1  95653466-95653532
            652-752             JAXUCZ010000004.1  95661288-95661388
            753-854             JAXUCZ010000004.1  95666033-95666134
            855-936             JAXUCZ010000004.1  95667168-95667249
            937-1325            JAXUCZ010000004.1  95669555-95669943
            1326-1525           JAXUCZ010000004.1  95678898-95679097
            1526-1616           JAXUCZ010000004.1  95684820-95684910
            1617-1716           JAXUCZ010000004.1  95687211-95687310
            1717-1776           JAXUCZ010000004.1  95688280-95688339
            1777-1852           JAXUCZ010000004.1  95688436-95688511
            1853-1988           JAXUCZ010000004.1  95690439-95690574
            1989-2126           JAXUCZ010000004.1  95691067-95691204
            2127-2222           JAXUCZ010000004.1  95692875-95692970
            2223-2340           JAXUCZ010000004.1  95693083-95693200
            2341-2462           JAXUCZ010000004.1  95693398-95693519
            2463-2651           JAXUCZ010000004.1  95694689-95694877
            2652-2770           JAXUCZ010000004.1  95695551-95695669
            2771-2953           JAXUCZ010000004.1  95697059-95697241
            2954-3063           JAXUCZ010000004.1  95698150-95698259
            3064-4795           JAXUCZ010000004.1  95700673-95702404
FEATURES             Location/Qualifiers
     source          1..4795
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q31"
     gene            1..4795
                     /gene="Smarcad1"
                     /note="SNF2 related chromatin remodeling ATPase with DExD
                     box 1"
                     /db_xref="GeneID:312398"
                     /db_xref="RGD:1309640"
     exon            1..240
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..3125
                     /gene="Smarcad1"
                     /EC_number="3.6.4.12"
                     /note="SWI/SNF-related, matrix-associated actin-dependent
                     regulator of chromatin, subfamily a, containing DEAD/H box
                     1; SWI/SNF-related, matrix-associated actin-dependent
                     regulator of chromatin, subfamily a, containing DEAD/H box
                     1`"
                     /codon_start=1
                     /product="SWI/SNF-related matrix-associated
                     actin-dependent regulator of chromatin subfamily A
                     containing DEAD/H box 1"
                     /protein_id="NP_001101334.2"
                     /db_xref="GeneID:312398"
                     /db_xref="RGD:1309640"
                     /translation="MNLFNLDRFRFEKRSKIEEAPEAAPQPSQPGPSSPISLSAEEEN
                     AEGEVSRANTPDSDVTEKTEDSSVPEPPDNESKASLSCFQNQRTIQEYIDLSSDSEDV
                     SPNCSSTVQEKKFSKDTVIIVSEPSEDEESHDLPSATRRNDISELEDLSELEDLKDAK
                     LQTLKELFPQRSDSDLLKLIDSTSTMDGAIAAALLKFGDAGGGPRKRKLSSSSEAYEE
                     DEANDDQSLKKPRGDRREESNESAEASSNWEKQESIVLKLQKEFPNFDKQELREVLKE
                     HEWMYTEALESLKVFAEDQDVQCASQSEVTNGKEVARNQNYSKNAAKIKMKQKISMKP
                     QNGFNKKRKKNVFNPKKAVEDSEYDSGSDAGSSLDEDYSSCEEVMEDGYKGKILHFLQ
                     DASIGELTLIPKCSQKKAQKIIELRPFNNWETLFTKMSKINGLSEDLIWNCKTVIQER
                     DVVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSLLNQSLSLKPYQKVGLNWLAL
                     VHKHGLNGILADEMGLGKTIQAIAFLAYLFQEGNKGPHLIVVPASTIDNWLREVNLWC
                     PTLNVLCYYGSQEERKQIRFNIHNKYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAI
                     FDEGHMLKNMGSIRYQHLMTINARNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTS
                     EIRRMFSSKTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKLLPPKKDQIELCA
                     MSEKQEQLYSGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLHRQYYTAEKLKEM
                     SQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYQHINSYQLDMDLILDSGKFRT
                     LGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEF
                     NTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLV
                     IKLISQGTIEESMLKINQQKLKLEQDMTTVDEADEGSMPADIATLLKTSMGL"
     exon            241..418
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            419..584
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            585..651
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            652..752
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            753..854
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            855..936
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1325
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1525
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1616
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1716
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1717..1776
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1852
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..1988
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2126
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2127..2222
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2223..2340
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2462
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2651
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2770
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2771..2953
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3063
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..4795
                     /gene="Smarcad1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctagttcatt gaaagctgtc agcctcctca gggaggtgct tcctatcaat atgaatcttt
       61 tcaacttgga ccgttttcgc tttgagaaaa ggagtaagat tgaggaagct cctgaagcag
      121 cccctcagcc ctcccagccc ggtccttcgt caccaatttc tcttagtgct gaagaggaga
      181 atgctgaagg ggaagttagc agggcaaaca ccccagactc agatgtaact gaaaaaacag
      241 aagattctag tgttccagaa cctccagaca atgaaagcaa agcaagttta tcatgtttcc
      301 aaaatcaaag aacaatacag gaatatattg atttatcatc tgatagtgaa gatgtttctc
      361 caaattgttc cagtacagtt caagagaaaa aattcagcaa agacacagta attatagttt
      421 cagagccatc tgaagatgaa gaatcccatg accttccttc tgctacacga agaaatgaca
      481 tctcagaact ggaagacctt tcagaattgg aagatcttaa agatgctaag cttcagacat
      541 tgaaggaact gtttccacaa agaagtgaca gtgatcttct aaagttgatt gactcaacaa
      601 gcactatgga tggagccatt gctgctgcct tgctgaagtt cggtgatgca ggtggtggac
      661 ccaggaaaag aaaattatct tcttcttctg aggcatatga agaggatgaa gctaatgatg
      721 atcagtcttt aaaaaagccg cgaggggatc gtagagaaga atcaaatgag tctgcagaag
      781 ctagcagcaa ctgggaaaag caagaaagta ttgtgttgaa attgcagaag gaattcccaa
      841 attttgataa acaggagtta agggaagtgc ttaaggagca tgagtggatg tacacagaag
      901 ccttggagtc tctgaaagtg tttgcggaag atcaagatgt gcagtgtgct tcacaaagtg
      961 aggttacaaa tggaaaagaa gttgcaagga atcaaaatta ttctaaaaat gcagctaaaa
     1021 taaagatgaa acagaaaatt tccatgaaac cacaaaatgg ctttaacaag aaacgtaaga
     1081 aaaatgtatt taatcctaag aaagccgtag aggactctga gtatgattcg ggttctgatg
     1141 ctgggagctc actggatgag gactacagca gttgtgaaga agtgatggag gacggctata
     1201 aaggcaaaat tctccacttc cttcaagatg cttcgattgg tgaactgact ttgattccta
     1261 agtgttctca gaaaaaggct cagaagataa tagaactccg gccctttaat aattgggaaa
     1321 ctctgtttac aaagatgtcc aaaatcaatg gcctatctga agatttgata tggaattgca
     1381 aaacggtaat tcaagaaagg gatgtagtta taagacttat gaacaaatgt gaagatattt
     1441 caaataaatt aaccaaacaa gttaccatgc ttactggaaa tggaggtgga tggaacatag
     1501 aacagccttc ccttctaaac caaagtttgt cactcaagcc ctatcagaag gttggtttga
     1561 attggctggc attggtgcat aaacatggac ttaatggcat tttggcagat gaaatgggcc
     1621 taggaaaaac cattcaagcc attgccttcc tggcatacct ctttcaagag ggtaataaag
     1681 ggcctcattt gattgttgtt ccggcctcca ccatagataa ctggttaaga gaagttaact
     1741 tatggtgccc tactttaaat gtgctctgtt actatggttc tcaagaagag cgtaaacaaa
     1801 ttagattcaa catccataat aaatatgaag attacaatgt aattgttacg acgtataatt
     1861 gtgcaatcag cagctctgat gaccgcagtc tctttcgacg cctgaaactg aattatgcaa
     1921 tttttgatga gggccatatg ctgaagaata tgggctctat ccgctaccag cacctaatga
     1981 caattaatgc acgaaaccgg ttactactca cgggaacacc tgtgcagaat aatctgctag
     2041 aactcatgtc attgttgaat tttgttatgc cacacatgtt tagcagtagc accagcgaaa
     2101 tccgaaggat gttttcttct aaaacgaaac cagcagatga acagagtata tacgaaaagg
     2161 agagaatagc acatgcaaaa caaatcataa agccctttat tctcagaaga gtgaaagagg
     2221 aggttcttaa gcttctgcct cccaagaagg atcagattga gctatgcgca atgtcagaga
     2281 agcaggagca actctactcg ggccttttta acagattgaa aaagtctatc aacaacctgg
     2341 aaaaaaacac agagatgtgc aatgtcatga tgcaattaag aaaaatggcc aatcatcctt
     2401 tactacaccg ccagtattac acggctgaga agctgaagga gatgtctcag ctaatgctga
     2461 aggaacctac gcattgtgag gcaaaccccg acctgatctt tgaagacatg gaagttatga
     2521 cagattttga actacatgtc ctttgtaaac agtatcaaca cattaatagt taccagttag
     2581 acatggattt aattttagat tctgggaaat tccgaacctt aggatgcatc ttgtctgagt
     2641 tgaaacagaa gggtgataga gtggtattat tcagccagtt taccatgatg ctggatatat
     2701 tagaggttct cttaaagcac catcaacata ggtacctccg attagatgga aagactcaga
     2761 tttctgaaag gatccatcta attgatgagt ttaatacaga tatggatatc tttgtgtttc
     2821 tcttgtcaac taaggcgggt ggattaggaa taaacctgac ctcagcaaat gttgttatac
     2881 ttcatgacat tgactgcaac ccatacaacg acaaacaagc ggaagacagg tgccatagag
     2941 ttggtcagac taaagaagta ttagttatta aattaataag ccaaggaacg attgaagagt
     3001 ccatgctaaa aattaaccaa caaaagttga agctagagca agacatgact acagtagatg
     3061 aagctgatga gggaagtatg ccagcggata tagccacgct actgaaaacg tcaatgggcc
     3121 tgtgaaagga caactcagaa ttcctgatcg atgagcaaat atcaacttgg tgcattcaag
     3181 gacattcaca tcacagtgac cgtggggttt atgagcattt gtaacgtttt ataatttcat
     3241 gttgcatttc acatagtatg gacaactttt tgccactaac tggattctcc agatactcac
     3301 atcctgaaga tgttgaataa tcatttttca aagcaatttt ctgaatgggg attagttggt
     3361 gattgtttgt aacaaatatg ctaatgcttt agaaatgtca gtatttttgt aattatttct
     3421 acctccaaat atatatacat atatatatat tgtctttcac tggataatgt gtgtagattt
     3481 acatgtgcct tatttgacaa tgtttatgtc ttattttgcc tgtctggttt gaaggtttga
     3541 ttatgttaaa gaatgcagct gtataggtcg ttagtcttca ttttatattg ctatttgaag
     3601 cagatgttca ccaatgtcag taagaactca gcctgaatca aaggtggcat tccatctact
     3661 aacatcccca ggtcctctcc ttctcccgtt agaacacatt tgtttggcta ggcactaagt
     3721 tgtttcccag tgagtaggaa ctggcctttc tcctgctctg gggctcagtt acttatttaa
     3781 ttttcttact gcacctctgg ctcattaact ctgcctactc ttgtgtgtgt taccatcagc
     3841 tttctctccc gcctttgctt ctcttaacca ttgcccagtc acttctgctc cagttttctc
     3901 tcacacattt cctactgctg tatcaccaag atcagcagat gctggtgaca tttttctagt
     3961 ccagcagaac agattaactt aaactacttc acttcaaagg aaactggatg tgacttcata
     4021 ctaaggtagc attaggtact gcatggaaat aggccattaa attcttaaca aaatataatt
     4081 taccagttcc cagaatttcc aatacaggac caccagaaga gaagccattg ttcaattcca
     4141 gttcagtgtg ggtgacaaag tgaaatttag aagtaaaatt gcctatttga tatttcagtc
     4201 tttattaact tttcatttaa attttgcctg tcagtctata ttgctgtttt tattataccc
     4261 cagattcttt gtataacttg tgagttttaa gtgttttgtt ttattatgta aatatcatta
     4321 taaataaact tatttataaa cgagagattg gttaattatt ggagctcata cttttcaaga
     4381 cgtcctggtt gctaaggtgc taggtaaact cttaggtggt tgacatgatc ctacagtgct
     4441 tttttttcag gtatctgaga ctctgactcc tgactcagta gatataatat tgaagatata
     4501 tgaatatatc agctatatct ccccactaca gggctacccg gaatctgcag gtgttaatgc
     4561 tacctctttg tgatcacagg acccaggttg cttagtcaag ttgttggaaa ttgtaccttt
     4621 taaactcaca gtgaatttct cttaactttt tttgtatgaa atgtatctcc cgcagtaggc
     4681 tcattggttg tggtgatgtt acatctaaat ttcttctaat gaaatgtagt tggattctcc
     4741 ctgtaatatt ccattattat gtctcgggtt taataaaaat atttgtgatc attaa
//
