LOCUS       NM_001271190            3748 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus SNF2 related chromatin remodeling ATPase 1
            (Smarca1), mRNA.
ACCESSION   NM_001271190 XM_002727681 XM_003752140 XM_229124
VERSION     NM_001271190.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3748)
  AUTHORS   Li,Y., Schulz,V.P., Deng,C., Li,G., Shen,Y., Tusi,B.K., Ma,G.,
            Stees,J., Qiu,Y., Steiner,L.A., Zhou,L., Zhao,K., Bungert,J.,
            Gallagher,P.G. and Huang,S.
  TITLE     Setd1a and NURF mediate chromatin dynamics and gene regulation
            during erythroid lineage commitment and differentiation
  JOURNAL   Nucleic Acids Res 44 (15), 7173-7188 (2016)
   PUBMED   27141965
REFERENCE   2  (bases 1 to 3748)
  AUTHORS   Yuan,J., Ghosal,G. and Chen,J.
  TITLE     The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA
            and participates in cellular response to replication stress
  JOURNAL   Mol Cell 47 (3), 410-421 (2012)
   PUBMED   22705370
REFERENCE   3  (bases 1 to 3748)
  AUTHORS   Yip,D.J., Corcoran,C.P., Alvarez-Saavedra,M., DeMaria,A.,
            Rennick,S., Mears,A.J., Rudnicki,M.A., Messier,C. and Picketts,D.J.
  TITLE     Snf2l regulates Foxg1-dependent progenitor cell expansion in the
            developing brain
  JOURNAL   Dev Cell 22 (4), 871-878 (2012)
   PUBMED   22516202
REFERENCE   4  (bases 1 to 3748)
  AUTHORS   Hargreaves,D.C. and Crabtree,G.R.
  TITLE     ATP-dependent chromatin remodeling: genetics, genomics and
            mechanisms
  JOURNAL   Cell Res 21 (3), 396-420 (2011)
   PUBMED   21358755
  REMARK    Review article
REFERENCE   5  (bases 1 to 3748)
  AUTHORS   Vermeulen,M., Eberl,H.C., Matarese,F., Marks,H., Denissov,S.,
            Butter,F., Lee,K.K., Olsen,J.V., Hyman,A.A., Stunnenberg,H.G. and
            Mann,M.
  TITLE     Quantitative interaction proteomics and genome-wide profiling of
            epigenetic histone marks and their readers
  JOURNAL   Cell 142 (6), 967-980 (2010)
   PUBMED   20850016
REFERENCE   6  (bases 1 to 3748)
  AUTHORS   Banting,G.S., Barak,O., Ames,T.M., Burnham,A.C., Kardel,M.D.,
            Cooch,N.S., Davidson,C.E., Godbout,R., McDermid,H.E. and
            Shiekhattar,R.
  TITLE     CECR2, a protein involved in neurulation, forms a novel chromatin
            remodeling complex with SNF2L
  JOURNAL   Hum Mol Genet 14 (4), 513-524 (2005)
   PUBMED   15640247
REFERENCE   7  (bases 1 to 3748)
  AUTHORS   Barak,O., Lazzaro,M.A., Lane,W.S., Speicher,D.W., Picketts,D.J. and
            Shiekhattar,R.
  TITLE     Isolation of human NURF: a regulator of Engrailed gene expression
  JOURNAL   EMBO J 22 (22), 6089-6100 (2003)
   PUBMED   14609955
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On or before Sep 7, 2012 this sequence version replaced
            XM_229124.6, XM_003752140.1, XM_002727681.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.33099.1,
                                           SRR26360190.1459131.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-316               JAXUCZ010000021.1  131943967-131944282 c
            317-418             JAXUCZ010000021.1  131939065-131939166 c
            419-585             JAXUCZ010000021.1  131935620-131935786 c
            586-686             JAXUCZ010000021.1  131935207-131935307 c
            687-787             JAXUCZ010000021.1  131935001-131935101 c
            788-967             JAXUCZ010000021.1  131931780-131931959 c
            968-1123            JAXUCZ010000021.1  131929933-131930088 c
            1124-1255           JAXUCZ010000021.1  131928702-131928833 c
            1256-1324           JAXUCZ010000021.1  131927914-131927982 c
            1325-1434           JAXUCZ010000021.1  131923784-131923893 c
            1435-1661           JAXUCZ010000021.1  131922951-131923177 c
            1662-1783           JAXUCZ010000021.1  131919140-131919261 c
            1784-1936           JAXUCZ010000021.1  131915485-131915637 c
            1937-2069           JAXUCZ010000021.1  131913603-131913735 c
            2070-2218           JAXUCZ010000021.1  131912685-131912833 c
            2219-2338           JAXUCZ010000021.1  131910534-131910653 c
            2339-2449           JAXUCZ010000021.1  131902297-131902407 c
            2450-2563           JAXUCZ010000021.1  131901928-131902041 c
            2564-2686           JAXUCZ010000021.1  131892869-131892991 c
            2687-2819           JAXUCZ010000021.1  131890428-131890560 c
            2820-2938           JAXUCZ010000021.1  131887496-131887614 c
            2939-3151           JAXUCZ010000021.1  131887171-131887383 c
            3152-3262           JAXUCZ010000021.1  131874684-131874794 c
            3263-3748           JAXUCZ010000021.1  131873152-131873637 c
FEATURES             Location/Qualifiers
     source          1..3748
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq35"
     gene            1..3748
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /note="SNF2 related chromatin remodeling ATPase 1"
                     /db_xref="GeneID:317575"
                     /db_xref="RGD:1561046"
     exon            1..316
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..3334
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /note="SWI/SNF related, matrix associated, actin dependent
                     regulator of chromatin, subfamily a, member 1"
                     /codon_start=1
                     /product="probable global transcription activator SNF2L1"
                     /protein_id="NP_001258119.1"
                     /db_xref="GeneID:317575"
                     /db_xref="RGD:1561046"
                     /translation="MEPDTATEAATVAASDARATIVVLEDEQPGPSTFKEEGAAAAAT
                     EATTATEKGEKKEKITSPFQLKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFL
                     LKQTELFAHFIQPSAQKSPTSPLNMKLARPRVKKDDKQSLISVGDYRHRRTEQEEDEE
                     LLSESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGK
                     TLQTIALLGYLKHYRNFPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAA
                     FIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREF
                     KSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLH
                     AVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDK
                     MRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVSNSGKMVALDKLLARIKEQGSR
                     VLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLST
                     RAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERI
                     VERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFACKESELTDEDIV
                     TILERGEKKTAEMNERMQKMGESSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEWIEP
                     PKRERKANYAVDAYFREALRVSEPKVPKAPRPPKQPNVQDFQFFPPRLFELLEKEILY
                     YRKTIGYKVPRNPELPNPAIAQREEQKKIDGAEPLTPQESEEKDKLLTQGFTNWTKRD
                     FNQFIKANEKYGRDDIDNVAREVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERG
                     EARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGKNYTEEEDRFLICMLHKMGFD
                     RENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKENMEIEERERAEK
                     KKRATKTPMSQKRKAESATESSGKKDVKKVKS"
     exon            317..418
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            419..585
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            586..686
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            687..787
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            788..967
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1123
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1255
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1324
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1434
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1661
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1783
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1936
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2069
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2218
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2338
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2339..2449
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2563
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2686
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2687..2819
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2938
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..3151
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            3152..3262
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
     exon            3263..3748
                     /gene="Smarca1"
                     /gene_synonym="RGD1561046"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaggtggggg acgagcgaag gggttggacg ctagtattcc ctacccctgc tctagcaagc
       61 tctttctagc gcagccaccg ctgtcgccca ggaacctccc ttctcccttt cctcgtccca
      121 cctcgtcttt cccgctccca acgccatgga gccggacacg gccacagagg cagccaccgt
      181 ggcagcctcg gatgccagag ccacaatcgt ggtcctagag gatgagcagc ccgggccgtc
      241 cacctttaaa gaggagggag cggctgctgc cgccaccgaa gccaccacgg ccactgagaa
      301 gggcgagaag aaggagaaaa tcacttctcc atttcaactc aaacttgctg ctaaaacttc
      361 caaatctgaa aaggaaatgg acccagaata tgaagagaaa atggtaaata tacccttgaa
      421 agcagacaga gcgaagagat ttgagttttt gctgaagcag acggaacttt ttgcacattt
      481 cattcaacct tcagcacaga agtctccaac atctcctctt aacatgaaac tggctcgtcc
      541 tcgagtaaag aaagatgaca agcagagctt gatttctgtg ggagactatc gccacaggcg
      601 cacagaacaa gaggaagatg aggagcttct gtcagagagt aggaaaacat cgaatgtgtg
      661 tgttagattt gaggtctcac cttcttatgt gaagggagga cccctgagag attatcagat
      721 tcgaggacta aactggttga tctctttgta tgaaaatgga gtcaatggta ttttagctga
      781 tgaaatgggc cttgggaaga ctttacaaac cattgctttg cttggttacc tgaaacatta
      841 cagaaacttt cctggacccc atatggtttt agttccaaag tctactttac ataactggat
      901 gaatgaattt aaacgatggg ttccgtctct ccgtgttatt tgtttcgttg gagacaaaga
      961 tgtgagagca gcttttattc gtgatgaaat gatgccagga gaatgggatg tttgtgtgac
     1021 ttcttatgag atggtaatta aagaaaaatc cgtgtttaaa aagtttcact ggagatactt
     1081 agtcattgat gaagctcaca gaataaaaaa tgaaaaatct aagctttcag agattgttcg
     1141 tgagttcaag tcaactaatc gcttacttct aactgggaca cctttgcaga ataacttgca
     1201 tgagctctgg gcattactta actttttatt gccggatgtc tttaattctg cagatgactt
     1261 tgattcttgg tttgatacta aaaattgcct tggtgatcaa aagcttgtgg aaagactcca
     1321 tgcagtttta aaaccattct tgttacgccg tataaaaact gatgtagaga aaagtctgcc
     1381 tccaaagaag gaaataaaga tttacttggg actgagtaaa atgcaacgag aatggtatac
     1441 aaaaattctg atgaaagata tcgatgtttt aaactcttct ggcaagatgg acaagatgcg
     1501 actattgaat attctgatgc agctccgaaa gtgttgtaat catccttatc tgtttgatgg
     1561 agcagagcct ggtccacctt atacgacaga tgagcacatt gtcagcaata gtggtaaaat
     1621 ggtagctctg gataagctat tggcgagaat taaagaacag ggatcaagag ttctcatctt
     1681 tagccagatg actcgactgc tagacatttt ggaggattat tgtatgtggc gtggttatga
     1741 gtattgtcga ctggatggac aaaccccaca tgaagaaaga gaggaagcaa tagaagcctt
     1801 caatgctccg aatagcagca aattcatctt tatgctgagt actagggctg gaggactcgg
     1861 aattaacttg gcaagtgctg acgtggttat cctatatgat tcagactgga atcctcaggt
     1921 tgatttacaa gctatggatc gggcacatcg cattggtcag aagaagccag tacgagtctt
     1981 ccgtctcatt acagacaaca cagtggaaga aaggattgta gagagagctg agataaaact
     2041 gagacttgat tcaattgtta tacagcaagg gagactcatt gaccaacaat ccaacaagct
     2101 ggcaaaagag gaaatgctac aaatgatacg ccatggagcc acacacgttt ttgcctgtaa
     2161 agaaagtgag ctgacggatg aagacattgt aactattctg gaaagagggg aaaagaagac
     2221 tgcagagatg aatgaacgca tgcagaaaat gggagagtca tctctaagaa atttcagaat
     2281 ggaccttgaa caaagtttgt acaagtttga aggagaagat tatagagaaa aacagaagct
     2341 tggtacggtg gaatggattg aacctcctaa acgagaacgc aaagccaact acgcagtgga
     2401 tgcctacttt agagaggctt tacgtgtcag cgagccaaag gtcccaaagg ctcctcggcc
     2461 tccaaaacag ccaaatgttc aagattttca attttttcca ccacgcttat ttgagctcct
     2521 ggaaaaggaa attctttatt atcggaagac tataggttac aaggtcccaa ggaatcctga
     2581 gctccccaac ccagctatag ctcaaagaga agagcaaaaa aagattgatg gagcagaacc
     2641 tcttacacca caagagagtg aagagaaaga taaacttctc acacaaggtt tcacaaactg
     2701 gactaagaga gattttaacc agtttattaa ggctaatgag aagtatggta gagatgacat
     2761 tgacaatgta gctcgagagg tagagggcaa gtcccctgag gaggtcatgg agtattcagc
     2821 tgtattttgg gaacgctgca atgaattaca ggacattgag aaaattatgg ctcaaattga
     2881 acgtggagaa gcaagaattc agcgaagaat cagtattaag aaagcactgg atgccaaaat
     2941 tgcaagatac aaggctccat ttcatcagtt acggattcag tacggaacca gtaaaggaaa
     3001 gaactatact gaagaagaag acagattcct catctgtatg ttgcacaaaa tgggctttga
     3061 cagagaaaat gtatatgaag aattgagaca gtgcgtacgg aatgctcccc agtttagatt
     3121 tgactggttt atcaagtcga gaactgccat ggaatttcag agacgctgta atactttgat
     3181 ttcattgatt gaaaaagaaa atatggaaat tgaggaaaga gagagagcag aaaagaagaa
     3241 acgggcaact aaaactccaa tgtcacagaa aagaaaagca gagtcagcta ctgagagctc
     3301 tggaaagaag gatgtcaaga aggtgaaatc ctaaagccta gaaataaagt tttaaatggg
     3361 aaactgctat tttcttgttc ccatcttcaa atgctaatta ccagttccag tgtattgatg
     3421 gtactctaag gaaaaaaact gaaatactct ttggttttga tttcttgcat attttatata
     3481 ttttacaatg ctttctacct gaaatgtgta gctttctatt tcatgcatct agtattttgt
     3541 gtactgtatt ttgtgcattt cgtgtcttca tcaaattcct ctcagtcctt gtttttttga
     3601 agcctgtgct gaggttttag cttttctatg ttttctatgc cgctgctttg aaagagaacc
     3661 tagattctat agctgtatta ttgttgtttc agactttaaa tttatatggc tgtggaaaaa
     3721 tgaattaaaa tgatttgagg agaaagac
//
