LOCUS       NM_001398651            6283 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus SLX4 structure-specific endonuclease subunit
            (Slx4), mRNA.
ACCESSION   NM_001398651 XM_006245835
VERSION     NM_001398651.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6283)
  AUTHORS   Wan,B., Yin,J., Horvath,K., Sarkar,J., Chen,Y., Wu,J., Wan,K.,
            Lu,J., Gu,P., Yu,E.Y., Lue,N.F., Chang,S., Liu,Y. and Lei,M.
  TITLE     SLX4 assembles a telomere maintenance toolkit by bridging multiple
            endonucleases with telomeres
  JOURNAL   Cell Rep 4 (5), 861-869 (2013)
   PUBMED   24012755
REFERENCE   2  (bases 1 to 6283)
  AUTHORS   Fugger,K., Chu,W.K., Haahr,P., Kousholt,A.N., Beck,H., Payne,M.J.,
            Hanada,K., Hickson,I.D. and Sorensen,C.S.
  TITLE     FBH1 co-operates with MUS81 in inducing DNA double-strand breaks
            and cell death following replication stress
  JOURNAL   Nat Commun 4, 1423 (2013)
   PUBMED   23361013
REFERENCE   3  (bases 1 to 6283)
  AUTHORS   Vannier,J.B., Pavicic-Kaltenbrunner,V., Petalcorin,M.I., Ding,H.
            and Boulton,S.J.
  TITLE     RTEL1 dismantles T loops and counteracts telomeric G4-DNA to
            maintain telomere integrity
  JOURNAL   Cell 149 (4), 795-806 (2012)
   PUBMED   22579284
REFERENCE   4  (bases 1 to 6283)
  AUTHORS   Fekairi,S., Scaglione,S., Chahwan,C., Taylor,E.R., Tissier,A.,
            Coulon,S., Dong,M.Q., Ruse,C., Yates,J.R. 3rd, Russell,P.,
            Fuchs,R.P., McGowan,C.H. and Gaillard,P.H.L.
  TITLE     Human SLX4 is a Holliday junction resolvase subunit that binds
            multiple DNA repair/recombination endonucleases
  JOURNAL   Cell 138 (1), 78-89 (2009)
   PUBMED   19596236
REFERENCE   5  (bases 1 to 6283)
  AUTHORS   Svendsen,J.M., Smogorzewska,A., Sowa,M.E., O'Connell,B.C.,
            Gygi,S.P., Elledge,S.J. and Harper,J.W.
  TITLE     Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and
            is required for DNA repair
  JOURNAL   Cell 138 (1), 63-77 (2009)
   PUBMED   19596235
REFERENCE   6  (bases 1 to 6283)
  AUTHORS   Andersen,S.L., Bergstralh,D.T., Kohl,K.P., LaRocque,J.R.,
            Moore,C.B. and Sekelsky,J.
  TITLE     Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with
            DNA structure-specific endonucleases in DNA repair and
            recombination
  JOURNAL   Mol Cell 35 (1), 128-135 (2009)
   PUBMED   19595722
REFERENCE   7  (bases 1 to 6283)
  AUTHORS   Munoz,I.M., Hain,K., Declais,A.C., Gardiner,M., Toh,G.W.,
            Sanchez-Pulido,L., Heuckmann,J.M., Toth,R., Macartney,T.,
            Eppink,B., Kanaar,R., Ponting,C.P., Lilley,D.M. and Rouse,J.
  TITLE     Coordination of structure-specific nucleases by human SLX4/BTBD12
            is required for DNA repair
  JOURNAL   Mol Cell 35 (1), 116-127 (2009)
   PUBMED   19595721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 21, 2021 this sequence version replaced XM_006245835.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.61637.1,
                                           SRR26643297.33130.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                JAXUCZ010000010.1  12032996-12033073
            79-805              JAXUCZ010000010.1  12034799-12035525
            806-1012            JAXUCZ010000010.1  12037229-12037435
            1013-1202           JAXUCZ010000010.1  12039663-12039852
            1203-1415           JAXUCZ010000010.1  12040621-12040833
            1416-1624           JAXUCZ010000010.1  12043025-12043233
            1625-1941           JAXUCZ010000010.1  12043361-12043677
            1942-2155           JAXUCZ010000010.1  12044288-12044501
            2156-2241           JAXUCZ010000010.1  12044883-12044968
            2242-2388           JAXUCZ010000010.1  12045691-12045837
            2389-2555           JAXUCZ010000010.1  12046774-12046940
            2556-4747           JAXUCZ010000010.1  12047637-12049828
            4748-4850           JAXUCZ010000010.1  12053209-12053311
            4851-5264           JAXUCZ010000010.1  12053861-12054274
            5265-6283           JAXUCZ010000010.1  12054667-12055685
FEATURES             Location/Qualifiers
     source          1..6283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..6283
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /note="SLX4 structure-specific endonuclease subunit"
                     /db_xref="GeneID:302953"
                     /db_xref="RGD:1566009"
     exon            1..78
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            79..805
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     CDS             451..5616
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /note="SLX4 structure-specific endonuclease subunit
                     homolog; BTB (POZ) domain containing 12"
                     /codon_start=1
                     /product="structure-specific endonuclease subunit SLX4"
                     /protein_id="NP_001385580.1"
                     /db_xref="GeneID:302953"
                     /db_xref="RGD:1566009"
                     /translation="MDESDDDFKELCASFFQRVKKNATKEASGERTRRKASGHTQERG
                     KRKEASQAVARSKALQGPSEKKPRLGSQTSRTKKQRAPKSQEGDPALPVNGKGGVLAP
                     TPDQPVLCERPQSTQTENAPNGDSTTTGMPSPSKPRASELVLQRMKQFKRADPERLRH
                     TSEESPLKTAPGESVPRSLQQEIVAGNEYKPKLHNTDSDAAMALALQQEFRKEEASSR
                     PDSLEEKGLFFCQICQKNLSAMNVTRREQHVNRCLDEAEKALRPAPPQIPDCPICGKQ
                     FLTAKSRISHLKRCAVRMEVGPQLLLQAVRLQTAQPEAGSSPQVPSFSNHVGDLKRKG
                     TTNKREPQRRWKVSKPEAPSEDLLVAMALSRSEMEHCPVVPPLRLENAYSEKKGPGAE
                     KKSRRKRPPVCPPQLVTQDSETTSRQIEDRVAQLLSEETELACTPPLPASKISKEERE
                     HASWRVRQPEGRRGFLWELSALTGAWVKESFYTVGLLPPLVSQCPPKEPELPLELPKQ
                     QEPSTQRPPASQSSLPVSHSPKSQLLSSSQREGQALQDLVDLAVEGLSSSPCSRSAGM
                     PTGLDLVPSSLPLTGFVLPCQKTLRKDDSVALSLGLLATDFGAMVNNPHLSDVQFQLD
                     SGEVLYAHKFVLYARCPLLIQCVNTEGFSAVEDGDLTQRVLLSDVSSEAAHAFLNYLY
                     TADTDVPPSLAPDLRSLALRFGVSDLVELCEQVPATADSEGEQPEHSEDCESRAENFQ
                     ALLRSVWGNEEEEAETLLKPEVCEEDREKVNEAEMDEIYEFAATQRKLLQGERAAATD
                     GNTNQHGEDSPVSEPSLAGVQKDRQLENTEQMASGLEREEVHEGDSIPLQDQCPDWAG
                     KAEAQDALEEAVDHPGFCSPSDSLQETGKECLPLHPAQAHDCKQLLPSNQRASLELSQ
                     VTVGHEEQSDRVRERQANMAQAPSPHPCCLPSQSSVGDSPSQSWLHLYHTSSLSPSVS
                     QSHISKVVSPSSPSPVTPAKQRRDSNILTLRKEAGHHKGRQNSSKLGRRSRSILISPA
                     KSPPIDLTQSVPEPLSPRAQDPLRRVKKEGEVILLLDSDEEWELEHIKTESVSKDSPG
                     GKIPEVSPRPSDLLSVIDVEGDQEHFPSPPKREAGLQQEEEGQLGDRPAPGHRHIPWL
                     FCSQTPSLGEDSATESSWLVPATPGASKSRDRSSQTQIRSLKIRTPSGETAQQTPRPP
                     VLEAAQKFSVIMPHTQPVTVGASDTRRQAYRSPSRPYLRRHKLSSSQPSCPVPDFTSW
                     CQKSSSPRPCPPNPPAADEVVEVGDSDDEQEVASHQENSSPVLDGDPPGPMGDYCWHE
                     PLSPIPIDHLNLERTGPLITSSPGSQVQEALQSDGWHSPGLGTTPIRGSCGALRESQE
                     QSSQAGSPESSKLSVLSQALWDDWDEEEGHSPEAPPVAQMLSARTRKPDRPETPKGAN
                     QRKNLPPKVPVTPMPRYSIMETPVLKRELDRFGVRALPKRQMVLKLKEIFQYTHQTLE
                     SDSEDEIQSSQVPPGVARSQASNTETCNPSRSGSYTQLKATAGLRTQRSKGPSKRKSL
                     QHQEEQLGESISHPSRSPAGEPSRPDGDAQLPASQECMATSVDGSDNSFSSQSSSGEF
                     GAALESVGEDKDEEDGVTASQVAMQAPDTEEAVRRYICSQPALHRKVLMYQPLQLAEL
                     QAELKQNGIPVAMGKLLDILDAQCVTFTTAAARKEKLRQKRRQPSGRKKKDQK"
     exon            806..1012
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1202
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1415
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1624
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1941
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            1942..2155
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2241
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            2242..2388
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2555
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..4747
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            4748..4850
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            4851..5264
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
     exon            5265..6283
                     /gene="Slx4"
                     /gene_synonym="Btbd12; RGD1566009"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcttcgct cgcaggcctc agggcgcaag cgcagccccg cggctctccg ttaagaaggt
       61 gcggctgcag agcgggagat acagagttag atgaacctat gtcctttatc actgtggaga
      121 ccttggagaa tcacctgatc acagagttca catgtgttct atcccagagg cagctgttgg
      181 acaacaaaag agggaagttt ttaaacaagt tgtttaacta cgggtccaaa ttgaagaaag
      241 atatgaaagt cattatggag aggagtacag tacttggttt gcaattgtgc aaagtctcca
      301 agtaaatcag agagaagaca gctgtagtga ggccagaggt gtggtacaac ctcagtgggc
      361 tcacgcacga gcgccgcatc tgtggacatg ttgccagtcc ggtcctcact cccctaaaga
      421 caaacacgaa accttaaaac aggtcaagtg atggatgagt cagatgatga tttcaaagaa
      481 ctctgtgcca gctttttcca aagggtgaaa aaaaatgcga ccaaagaagc atcaggagag
      541 aggacgaggc ggaaggcctc cgggcacact caggaaagag gcaaacggaa agaagccagc
      601 caagctgtcg ccaggagcaa agcccttcaa ggcccttcag agaagaaacc tcgattaggc
      661 agccagacct ctaggactaa aaagcaaagg gcacccaaat ctcaagaagg ggaccccgct
      721 ctccctgtga atggaaaggg aggtgttctt gctcctaccc cagatcagcc tgtgttgtgt
      781 gaaagaccac agagcactca gacagagaat gctcccaatg gcgactccac gacgactggt
      841 atgccaagcc cctccaagcc cagagcctcg gagctggttc tccaacggat gaagcagttc
      901 aagagagcgg accctgagcg cttgagacat acctcagaag aatcccccct caagactgca
      961 ccgggagaaa gtgtcccaag gagcctgcaa caggagatag tggcgggaaa cgagtataaa
     1021 cccaagcttc acaacacaga cagcgatgct gcaatggccc tggccttaca gcaggaattt
     1081 agaaaggagg aagcttcctc acgtcctgac agcctggagg agaagggctt gttcttctgt
     1141 caaatatgtc agaaaaacct ctcagcaatg aatgtgactc ggagggagca acatgtgaac
     1201 agatgcctgg acgaggcaga gaaggcactg agacctgctc cacctcagat ccctgattgc
     1261 ccaatatgtg gtaaacagtt cctcaccgcc aagagccgaa tcagtcactt gaagcggtgc
     1321 gcagtgagga tggaggtagg ccctcagctc ctgcttcagg ctgtgaggct gcagacagct
     1381 cagccggagg cgggcagcag ccctcaggta cccagtttca gcaaccatgt tggagatttg
     1441 aaacggaaag gaaccaccaa taagagggag ccacagagga gatggaaagt cagtaaacct
     1501 gaggctccgt ccgaagacct gctggtggcc atggctctgt ctcgttctga gatggagcac
     1561 tgtccagttg tgcccccact cagactggaa aatgcttatt ctgagaagaa ggggccagga
     1621 gcagagaaga aaagtcgcag gaagagaccc ccggtgtgtc ccccacagtt ggtaacccaa
     1681 gactctgaga ccacaagtag acagatcgag gatcgtgtcg cccagctcct gtcagaggaa
     1741 acagaactgg cttgtacccc accacttcct gccagcaaga tttctaagga agaacgggaa
     1801 cacgcaagct ggcgagtgcg gcagcctgaa gggaggcggg gctttctgtg ggaactcagt
     1861 gcccttacag gagcctgggt taaggagtcc ttctacacag tgggcctgct tcctccactt
     1921 gtgtcccagt gccctcccaa ggagcccgag ctacccctgg agctgcccaa acaacaagag
     1981 ccaagcacac agaggccacc tgcttcccag agcagcctcc ccgtgagcca cagccccaag
     2041 agccagctgc tgtcctctag ccagagggaa ggccaagctc ttcaggacct tgtggacttg
     2101 gcagtcgagg ggctgagctc tagtccatgc tccaggagtg cgggcatgcc cacagggttg
     2161 gacttggtac ctagcagcct tccactgacg ggatttgttc taccatgtca gaagaccctt
     2221 aggaaggatg acagtgtcgc actctctctt gggttattgg caacagactt tggggccatg
     2281 gtcaataatc cgcacctgag tgatgtccag tttcagcttg acagcggaga ggtgctgtat
     2341 gcccacaagt ttgttctgta tgctcggtgc ccacttctta ttcagtgtgt aaatacggaa
     2401 ggcttctctg ctgtagagga tggggatctg acccagcgtg tcctgctgag tgacgtgagc
     2461 tctgaggctg cccacgcatt tctgaactac ctctacacgg cagacactga cgtgcctccc
     2521 agcctggctc ctgatctgcg ttccctggcc ctaaggtttg gtgtgagtga cctcgttgag
     2581 ctgtgtgaac aagtgcctgc cacagcagac tcagagggag agcagccaga gcacagcgag
     2641 gattgtgaga gcagagcaga gaacttccaa gcgctcctga ggtccgtgtg ggggaatgaa
     2701 gaggaggaag cggagactct gttgaaacct gaggtctgtg aagaagacag agaaaaagtg
     2761 aatgaggcgg aaatggacga gatatatgaa tttgcagcta cgcagaggaa gcttctccag
     2821 ggggaaagag cagcagccac ggatgggaac actaaccagc acggggagga cagtccagtt
     2881 tctgagcctt ccctggcagg tgtccagaag gacagacagc tcgaaaatac agagcaaatg
     2941 gcgtctgggt tagaaagaga agaggtacat gaaggagatt ccattccact gcaggaccag
     3001 tgcccagact gggcagggaa agcagaggcc caggatgcac tggaggaggc agttgaccac
     3061 cctggcttct gcagcccttc tgacagcctc caagagacag ggaaagaatg cttgcctttg
     3121 cacccagccc aggcccatga ctgcaaacag ctccttccat caaatcaaag agcgtcattg
     3181 gaactgtcac aagtaacagt tggtcatgaa gagcagagtg accgcgtcag ggagaggcag
     3241 gcaaacatgg cccaggcacc ttctccacac ccctgctgcc tcccgtcaca gtcttctgtg
     3301 ggtgacagtc ccagccagtc atggcttcac ctataccaca caagcagttt gtcaccctca
     3361 gtgtcccagt cacacatttc caaggtggtg tccccaagct caccgtctcc agttacacca
     3421 gctaagcaga ggagggacag taacattctc acattacgga aagaagcagg ccaccacaaa
     3481 ggcagacaaa acagctccaa attgggacgc agaagtagga gcattctgat ttccccagca
     3541 aagtctccgc ccattgacct gacgcagtct gtacctgagc ccctgagccc cagggcccag
     3601 gatcctctgc gccgtgtgaa gaaggagggc gaagtcatcc tcttactgga ttcagatgag
     3661 gagtgggagc tggagcacat caagacagag tccgtttcta aagactctcc aggagggaaa
     3721 attccagaag ttagccccag gccctctgac ctgttgtcag tcattgatgt agagggagat
     3781 caagaacatt tcccaagccc accgaagaga gaggccgggc tgcagcagga agaggagggg
     3841 cagctgggag accggcctgc gccgggccac agacacatcc cctggctctt ctgcagccag
     3901 acacccagcc tgggtgagga cagcgctacc gagagctcct ggctggtgcc tgccaccccc
     3961 ggggccagca agagtcgtga tcgctcatct cagacccaga tcagaagcct taagatcagg
     4021 actccatcag gtgagactgc tcagcaaaca ccaaggcctc ccgtgctgga agcagcccag
     4081 aagttctctg tgatcatgcc acatacacag cctgttactg taggagcctc agacaccaga
     4141 agacaggctt acagaagccc ttcccgtccc tacctcagac gccacaagct ctcttcttca
     4201 cagccatcat gtcctgttcc tgattttacc agctggtgcc aaaaatcctc ctcacctaga
     4261 ccatgcccac caaatccgcc tgcagccgat gaagtggtag aagttgggga cagtgatgat
     4321 gagcaggagg tggcttccca tcaagaaaac agcagccctg tgctagatgg tgacccccca
     4381 ggtcccatgg gtgactactg ttggcatgag cctctttcac caattccaat tgaccacttg
     4441 aacctggagc ggactggccc cttgatcaca agcagtccag gcagtcaggt ccaggaggct
     4501 ctacagagtg atggctggca ctccccagga cttggcacca cccccatccg aggaagctgt
     4561 ggtgctctca gagagtctca agagcagtcc tcacaggctg gctctccaga gagcagcaaa
     4621 ctgagtgtcc ttagccaggc tctgtgggat gactgggatg aggaggaagg acattctcca
     4681 gaggccccac ctgtggccca aatgctgagt gccagaactc ggaagccaga caggccagag
     4741 acaccaaaag gtgctaacca gagaaagaac ttgcccccca aagtgcctgt aaccccaatg
     4801 ccaaggtatt cgatcatgga gaccccagtg ctgaagagag aactggacag gtttggagtc
     4861 cgtgctctgc ccaaacgcca gatggttcta aaactgaagg agattttcca gtacactcac
     4921 cagactctgg agtcagactc tgaggatgag atccagtcct cccaggtacc cccaggggta
     4981 gctcgcagcc aggcatcgaa cactgagacc tgcaaccctt caaggtcagg aagttacacc
     5041 cagctcaagg ccactgcagg tctccggact caaagatcca agggccccag taaaaggaag
     5101 agccttcaac atcaggagga gcagctcggt gaaagcattt cccacccgag caggtcacca
     5161 gctggggagc cttcacgccc tgatggtgac gcccagctcc cagcctccca ggagtgcatg
     5221 gctacctctg tggatggcag cgacaactcc tttagctctc agagctcctc tggtgagttt
     5281 ggggctgcct tggagtctgt aggcgaagac aaggatgagg aggatggcgt caccgcgtca
     5341 caggtagcga tgcaggcccc agacacagag gaggcggtga ggcgctacat ctgctcgcag
     5401 cctgccctgc acaggaaggt cctgatgtac cagcctctgc agctggctga gctgcaggct
     5461 gagctgaagc agaacggcat tcctgtggcc atgggcaagc tgctggacat cctggatgct
     5521 caatgtgtca ccttcacgac tgctgccgcc cgcaaggaga agctcagaca gaagaggcgg
     5581 cagccctcgg gccgaaagaa aaaggatcag aaatgaccgt cctccaccca gttagacctg
     5641 ccagaggcct gagcacctag tgtaagggag gcctccacag tatgtcgtag gacgtggacc
     5701 tgtgtctgtg taaaggacaa gaagtcttct gcactctaac tgtgtgtgtc acccttggtc
     5761 tcagagcaga ccctcccccc tcagccagca ctagttttcc ccctttggcc caagcagggt
     5821 ccccatccta tgtgtacctg aaaggcagtg ggccatacca gctgaccagg ccaagaccca
     5881 agcctcttct cttgccagtg tccagcacag ccaagcacac cacggcggac cagacaggat
     5941 gggcagcctg caccactatt gtcataggtg ctcttccgcc ctgtgcctgc ccagacactt
     6001 gccactgtca ccagcattct tcaagtagga ctgtgagtag ggcccagtac agctttgaag
     6061 acccccaaag taagcatgtt tgtgggctct gcccatttgt gttaggcctc tttgacccag
     6121 tgtggactct gggaccagaa aaaacccaga agtttggatt tctacagctt gtgaatgtcc
     6181 ttatgtgttt taaatacagt gaagttgttt tatatgatgt gcaataaaaa acaaagaagg
     6241 ctttatttaa aaaaaaaaca ataaacttag acactcctct ctg
//
