LOCUS       NP_001124023              97 aa            linear   ROD 20-MAR-2023
DEFINITION  secreted Ly-6/uPAR domain-containing protein 2 precursor [Rattus
            norvegicus].
ACCESSION   NP_001124023 XP_001073673 XP_235419
VERSION     NP_001124023.1
DBSOURCE    REFSEQ: accession NM_001130551.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 97)
  AUTHORS   Lyukmanova EN, Shulepko MA, Shenkarev ZO, Bychkov ML, Paramonov AS,
            Chugunov AO, Kulbatskii DS, Arvaniti M, Dolejsi E, Schaer T,
            Arseniev AS, Efremov RG, Thomsen MS, Dolezal V, Bertrand D, Dolgikh
            DA and Kirpichnikov MP.
  TITLE     Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and
            Pharmacology of Interactions with Different Types of Acetylcholine
            Receptors
  JOURNAL   Sci Rep 6, 30698 (2016)
   PUBMED   27485575
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 97)
  AUTHORS   Allan CM, Procaccia S, Tran D, Tu Y, Barnes RH 2nd, Larsson M,
            Allan BB, Young LC, Hong C, Tontonoz P, Fong LG, Young SG and
            Beigneux AP.
  TITLE     Palmoplantar Keratoderma in Slurp2-Deficient Mice
  JOURNAL   J Invest Dermatol 136 (2), 436-443 (2016)
   PUBMED   26967477
REFERENCE   3  (residues 1 to 97)
  AUTHORS   Arredondo J, Chernyavsky AI, Jolkovsky DL, Webber RJ and Grando SA.
  TITLE     SLURP-2: A novel cholinergic signaling peptide in human
            mucocutaneous epithelium
  JOURNAL   J Cell Physiol 208 (1), 238-245 (2006)
   PUBMED   16575903
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 28, 2008 this sequence version replaced
            XP_001073673.1, XP_235419.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB727142.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN16676808
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..97
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     Protein         1..97
                     /product="secreted Ly-6/uPAR domain-containing protein 2
                     precursor"
                     /note="secreted Ly-6/uPAR domain-containing protein 2"
                     /calculated_mol_wt=8117
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=2538
     Region          23..97
                     /region_name="TFP_LU_ECD_SLURP2"
                     /note="extracellular domain (ECD) found in Secreted
                     Ly-6/uPAR-related protein 2 (SLURP-2) and similar
                     proteins; cd23561"
                     /db_xref="CDD:467091"
     CDS             1..97
                     /gene="Slurp2"
                     /gene_synonym="RGD1308195"
                     /coded_by="NM_001130551.1:23..316"
                     /db_xref="GeneID:315074"
                     /db_xref="RGD:1308195"
ORIGIN      
        1 mrllfwflla vvlsmelavt qgmfchlckg fggcshpfrc pgntthcvii atrspisftd
       61 lplvtkmcyn tcpdvpslgl gphvsivccq snlcnrd
//
