LOCUS       NM_001130544             597 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus secreted Ly6/Plaur domain containing 1 (Slurp1),
            mRNA.
ACCESSION   NM_001130544 XM_001073602 XM_216966
VERSION     NM_001130544.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Adeyo O, Oberer M, Ploug M, Fong LG, Young SG and Beigneux AP.
  TITLE     Heterogeneity in the properties of mutant secreted lymphocyte
            antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de
            Meleda
  JOURNAL   Br J Dermatol 173 (4), 1066-1069 (2015)
   PUBMED   25919322
REFERENCE   2  (bases 1 to 597)
  AUTHORS   Swamynathan S and Swamynathan SK.
  TITLE     SLURP-1 modulates corneal homeostasis by serving as a soluble
            scavenger of urokinase-type plasminogen activator
  JOURNAL   Invest Ophthalmol Vis Sci 55 (10), 6251-6261 (2014)
   PUBMED   25168896
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 597)
  AUTHORS   Adeyo O, Allan BB, Barnes RH 2nd, Goulbourne CN, Tatar A, Tu Y,
            Young LC, Weinstein MM, Tontonoz P, Fong LG, Beigneux AP and Young
            SG.
  TITLE     Palmoplantar keratoderma along with neuromuscular and metabolic
            phenotypes in Slurp1-deficient mice
  JOURNAL   J Invest Dermatol 134 (6), 1589-1598 (2014)
   PUBMED   24499735
REFERENCE   4  (bases 1 to 597)
  AUTHORS   Moriwaki Y, Watanabe Y, Shinagawa T, Kai M, Miyazawa M, Okuda T,
            Kawashima K, Yabashi A, Waguri S and Misawa H.
  TITLE     Primary sensory neuronal expression of SLURP-1, an endogenous
            nicotinic acetylcholine receptor ligand
  JOURNAL   Neurosci Res 64 (4), 403-412 (2009)
   PUBMED   19409425
  REMARK    GeneRIF: These findings suggest that SLURP-1 is expressed in a
            subset of primary peptidergic sensory neurons.
REFERENCE   5  (bases 1 to 597)
  AUTHORS   Chimienti F, Hogg RC, Plantard L, Lehmann C, Brakch N, Fischer J,
            Huber M, Bertrand D and Hohl D.
  TITLE     Identification of SLURP-1 as an epidermal neuromodulator explains
            the clinical phenotype of Mal de Meleda
  JOURNAL   Hum Mol Genet 12 (22), 3017-3024 (2003)
   PUBMED   14506129
REFERENCE   6  (bases 1 to 597)
  AUTHORS   Fischer J, Bouadjar B, Heilig R, Huber M, Lefevre C, Jobard F,
            Macari F, Bakija-Konsuo A, Ait-Belkacem F, Weissenbach J, Lathrop
            M, Hohl D and Prud'homme JF.
  TITLE     Mutations in the gene encoding SLURP-1 in Mal de Meleda
  JOURNAL   Hum Mol Genet 10 (8), 875-880 (2001)
   PUBMED   11285253
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 28, 2008 this sequence version replaced
            XM_001073602.1, XM_216966.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DV213922.1, BF522186.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN16093046
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..597
                     /gene="Slurp1"
                     /gene_synonym="RGD1308768"
                     /note="secreted Ly6/Plaur domain containing 1"
                     /db_xref="GeneID:300016"
                     /db_xref="RGD:1308768"
     exon            1..86
                     /gene="Slurp1"
                     /gene_synonym="RGD1308768"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..361
                     /gene="Slurp1"
                     /gene_synonym="RGD1308768"
                     /note="secreted Ly-6/uPAR-related protein 1"
                     /codon_start=1
                     /product="secreted Ly-6/uPAR-related protein 1 precursor"
                     /protein_id="NP_001124016.1"
                     /db_xref="GeneID:300016"
                     /db_xref="RGD:1308768"
                     /translation="MTLRWAVWLLLLAAWSMGYGEAFRCYTCEQPTAINSCKNIVHCK
                     LEDTACKTVLETVEAEFPFNHSPMVTRSCSSSCLATDPDGIGVAHPVFCCFRDLCNSG
                     FPGLVTGL"
     exon            87..206
                     /gene="Slurp1"
                     /gene_synonym="RGD1308768"
                     /inference="alignment:Splign:2.1.0"
     exon            207..597
                     /gene="Slurp1"
                     /gene_synonym="RGD1308768"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggctccca gctccagagc cctgaagaat gacccttcgc tgggccgtgt ggctgctgct
       61 cctggcagcc tggagcatgg gctatggtga ggccttcaga tgctatacct gtgagcagcc
      121 cacggccatt aactcatgca agaatattgt tcactgcaag ctggaagaca cagcctgtaa
      181 gactgttttg gagacagtgg aagcagagtt ccctttcaac cacagtccca tggtgacccg
      241 ctcctgctcc agctcctgcc tggccaccga ccctgatggc attggggttg cccatcctgt
      301 cttctgttgc ttccgtgatc tctgcaactc agggtttcca ggtttggtga caggcctcta
      361 gccacacagg gaccctcgtt cttcctgcat ctactctcct ggcagggccc ggtgctgtct
      421 gcacttgcct ctgcatgctt ggctctgtga gcagaactca ctgggcctcg gctcactcag
      481 tgtccaccaa acttgtggaa aataaaacaa gtcaagggtg aggggcctct ctgttcttcc
      541 tgggcaccgg gaacctgaag tgctggcctg cagggaagac aggctgtatt atggcac
//
