LOCUS       NM_001106057            4248 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus SLIT and NTRK-like family, member 6 (Slitrk6),
            mRNA.
ACCESSION   NM_001106057 XM_001077765 XM_224480
VERSION     NM_001106057.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4248)
  AUTHORS   Um JW, Pramanik G, Ko JS, Song MY, Lee D, Kim H, Park KS, Sudhof
            TC, Tabuchi K and Ko J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
REFERENCE   2  (bases 1 to 4248)
  AUTHORS   Tekin M, Chioza BA, Matsumoto Y, Diaz-Horta O, Cross HE, Duman D,
            Kokotas H, Moore-Barton HL, Sakoori K, Ota M, Odaka YS, Foster J
            2nd, Cengiz FB, Tokgoz-Yilmaz S, Tekeli O, Grigoriadou M, Petersen
            MB, Sreekantan-Nair A, Gurtz K, Xia XJ, Pandya A, Patton MA, Young
            JI, Aruga J and Crosby AH.
  TITLE     SLITRK6 mutations cause myopia and deafness in humans and mice
  JOURNAL   J Clin Invest 123 (5), 2094-2102 (2013)
   PUBMED   23543054
REFERENCE   3  (bases 1 to 4248)
  AUTHORS   Matsumoto Y, Katayama K, Okamoto T, Yamada K, Takashima N, Nagao S
            and Aruga J.
  TITLE     Impaired auditory-vestibular functions and behavioral abnormalities
            of Slitrk6-deficient mice
  JOURNAL   PLoS One 6 (1), e16497 (2011)
   PUBMED   21298075
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4248)
  AUTHORS   Katayama K, Zine A, Ota M, Matsumoto Y, Inoue T, Fritzsch B and
            Aruga J.
  TITLE     Disorganized innervation and neuronal loss in the inner ear of
            Slitrk6-deficient mice
  JOURNAL   PLoS One 4 (11), e7786 (2009)
   PUBMED   19936227
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4248)
  AUTHORS   Aruga J and Mikoshiba K.
  TITLE     Identification and characterization of Slitrk, a novel neuronal
            transmembrane protein family controlling neurite outgrowth
  JOURNAL   Mol Cell Neurosci 24 (1), 117-129 (2003)
   PUBMED   14550773
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473951.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224480.4, XM_001077765.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB605610.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4248
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q23"
     gene            1..4248
                     /gene="Slitrk6"
                     /note="SLIT and NTRK-like family, member 6"
                     /db_xref="GeneID:290467"
                     /db_xref="RGD:1306550"
     exon            1..523
                     /gene="Slitrk6"
                     /inference="alignment:Splign:2.1.0"
     exon            524..4248
                     /gene="Slitrk6"
                     /inference="alignment:Splign:2.1.0"
     CDS             548..3070
                     /gene="Slitrk6"
                     /note="SLIT and NTRK-like protein 6"
                     /codon_start=1
                     /product="SLIT and NTRK-like protein 6 precursor"
                     /protein_id="NP_001099527.1"
                     /db_xref="GeneID:290467"
                     /db_xref="RGD:1306550"
                     /translation="MKLRICLLYPSLLACLSLQSQSPMPPVRGSCDTLCTCEEKDGIM
                     IINCEEKGINTLSQISVPPSRPFHLSLLNNGLTTLHTNDFSGLTNALSIHLGFNNIAD
                     IETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEQSAFSKLN
                     RLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDN
                     KWACNCELLQLKNWLENMPPQSIIGDVICYSPPLFKGSILSRLKKESICPTPPVYEEH
                     EDPAGSLLAITSSTSDSRLSSKNTSILKQPTKAPGSVPYLTKPSTQLPVPYCPVPCNC
                     KVLSPSGLLIHCQERNIESVSDLQPPPHNPRKLILAGNIIHTLMKADLMDYFTLEMLH
                     LGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLYKGMFLGLSSLEYLYLEYNAVKEIL
                     PGTFNPMPKLKVLYLNNNLLHVLPAHIFLGIPLTRVNLKTNQFTHLPVSNILDDLDLL
                     IQIDLEDNPWDCSCDLVGLQQWIHKLGKGTVTDDILCASPGHLDKKELKALNSELLCP
                     GLVNNPSMPTQTSYIIVTSPTMAADAAGTLLSSLTDAVPLSVLILGLLIVFITIVFCA
                     AGIVVFVLHRRRRYKKKKVEEQLRDTSPVHLQYSMYGHKTTHHTTERPSSSLYEQHMV
                     SPMVHVYRSPSFGPKHLEEVEERSDKEGNDAKHLQRSLLERENHSPLTGSNMKYKVVD
                     QSTDFLPFQDASLLYRNILDKERELQQLGITEYLRKNIAQLQPDVEVNYPGAHEELKL
                     METLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT"
ORIGIN      
        1 agtctcttta tttacgccta cctcccagtc cttggcaatc tgactaataa caaactgagc
       61 taactagaaa gactcgaccg agagaggaag gacagcatta cagcagtctg gatcttcaac
      121 caaagaaagc aagagtgaac acccccggtc tccgcaaagc ttcttgttta tttactgtga
      181 ccaccagctt gtcaatggtt aactatatgc aaaacaaagt cagcatagct gtgaagtacg
      241 ctgtgaatat taattggggg agaaaaggac tcgggcttca ggatgctcca gtgtgtgctc
      301 tgtctgcaac actttcaatg aaaataagga ctcagcgttt tgcctttgac cagatgtttt
      361 aactttctga agctacggga cttgacagaa agtgatattt gaggagaaag tgcactgtgg
      421 tcctgtggtt ggtgttttct ttttcaataa ggaaactgac cgactttgga cacctcttcc
      481 agctgggcat ttcttacagc accaggaagt gtctgcttta cagacacgga tcacatcgta
      541 ggagaaaatg aagctgagga tttgtctcct ttatccctct cttcttgctt gtctatctct
      601 acagtcgcag tcacccatgc ccccagtcag aggctcttgc gacactcttt gtacttgtga
      661 agagaaagat ggcataatga taataaattg tgaagaaaag ggcatcaata cattatccca
      721 aataagtgtg ccaccgtcac gacctttcca cttaagttta ttaaataatg gcttgacaac
      781 gctccacaca aatgactttt ctgggcttac caatgccctt tcaatacacc ttggatttaa
      841 caacatagca gatatcgaga caggtgcatt taatggcctt ggacttctta aacaacttca
      901 tatcaatcac aattccttgg agattctcaa agaggatacc ttccacggtt tggagaacct
      961 ggaatttttg caggctgata ataatttcat tacagtgatt gaacagagtg ccttcagtaa
     1021 gctcaacagg ctgaaagtgt taattttaaa tgacaatgcc atcgagagtc ttcctccaaa
     1081 catatttcga ttcgttcctt taacccatct agatcttcgt ggaaaccagt tgcaaacgtt
     1141 gccttatgtt ggctttttag aacacattgg ccggatattg gatctccagt tggaggacaa
     1201 taagtgggcc tgcaattgtg aattattgca gctaaagaac tggctggaaa atatgcctcc
     1261 acagtctatc attggtgacg tcatatgcta cagccctcca cttttcaaag gaagcatact
     1321 gagccgattg aaaaaggaat ctatttgccc tactccccca gtgtatgaag agcacgagga
     1381 cccagcaggg tctttgttgg ccataacatc ttccacaagt gacagccgcc tatcaagcaa
     1441 gaatacatcc attttaaaac aacccaccaa agcgccaggt tccgtacctt accttacgaa
     1501 gccgtccact cagcttccgg taccctattg tcctgttccg tgcaactgca aagttctctc
     1561 cccttcagga cttctaatcc actgtcagga acgcaatatt gaaagtgtgt cagatctgca
     1621 acctcctcca cacaatccta gaaagctgat ccttgcaggc aatattattc atactttaat
     1681 gaaggctgac ctgatggact atttcacgtt ggaaatgctt cacttgggaa acaatcgtat
     1741 tgaagttctt gaagaagggt catttatgaa cctgacaagg ctccagaaac tctatctcaa
     1801 tggcaaccat ctgaccaaac tatataaagg catgttcctt ggtctttcca gtctcgagta
     1861 tttgtatctc gagtacaatg cggtaaagga aatattacca gggaccttca acccaatgcc
     1921 taaactgaaa gttctttatt taaataacaa tctccttcac gttttaccgg cacatatttt
     1981 tttaggtatt cctctaacta gagtaaatct taaaacaaac caattcaccc atttacctgt
     2041 aagcaacatc ttagatgacc ttgacttact gatacagatt gaccttgagg ataacccatg
     2101 ggattgctcc tgtgacctgg ttggattgca gcaatggata cacaagcttg gcaagggcac
     2161 cgtgacggat gacatcctct gcgcttcccc agggcatctt gacaaaaagg aattaaaagc
     2221 cctcaacagt gaacttctct gccctggttt agtgaataac ccttccatgc caactcagac
     2281 tagctacatt attgtcactt ctcccacaat ggcagccgat gcggctggta cccttttgag
     2341 ttccctaact gatgctgtgc ccctatcggt tctgatatta ggacttctga ttgtgttcat
     2401 aactattgta ttctgcgccg cggggatagt ggtatttgtc ctccaccgca gaagaagata
     2461 caagaagaaa aaggtagagg agcaactgag agacaccagt cctgtacacc tgcagtacag
     2521 catgtatggt cataaaacaa ctcaccatac aacggaaagg ccctcttcct ctctctacga
     2581 acagcacatg gtgagcccaa tggttcacgt ctacagaagc ccatccttcg gtccaaagca
     2641 tttggaagaa gttgaagaaa gaagtgataa agaaggaaac gatgcgaagc atcttcaaag
     2701 gagcctgttg gaacgagaaa atcattcacc ccttacaggt tcaaatatga aatacaaagt
     2761 cgtagaccaa tcaacagatt tcctaccttt tcaggatgcg agtttactat acaggaacat
     2821 tttggacaaa gaaagagaac ttcagcagct tggcatcaca gagtacctac ggaaaaatat
     2881 tgctcagctc cagccagatg tagaggttaa ctatcctgga gcccacgagg agctgaaact
     2941 aatggaaact ctgatgtact cacgacccag gaaggtgctg gtagaacaga ctaaaaatga
     3001 gtattttgag ctcaaagcga acttgcatgc tgagcctgac tatctagaag tcttggaaca
     3061 gcagacatag aggaaatggt tatgggcttt tgcagaaagg ctgtgattct gacttaagtc
     3121 cagacctttg aaataagtgc cttacgcggg tgtcatcaat cagaattcag cacagcagta
     3181 atcctatggg agataaaaga agaaagtgaa actcagggat aattgaggaa gccatggcat
     3241 tatcatcagg cagtatagcc tgttccaaat aaagcaagtc cttgcacata actgctgcag
     3301 gggttatagt agaattgctt cacatgctta caagtatttg atagaatttc tcttgcacac
     3361 ctaaagggtt gaacatagaa aaagctccag tttcttgaat actccattca tgactaaata
     3421 caattaaatc tcatcagtta agtatatacc tgtatatata tatatacata ccatgtaagg
     3481 aatatattca taaccaacgt atatgtcaga aatttaaatg gccaaatgca ccaaattttc
     3541 tcaaaatgaa gtgaaaaggg aactggaact taaattttga aatggctata gtgattaaaa
     3601 atgtaaattt tgtaattatg tgggccatta atgattcaca atttttaaca aggaatgaat
     3661 agacaaatgc cactgctaag ctttctgaat taagactcaa gatggcaaat agttcatgtg
     3721 ggaaactaag ctaacgtgtt agtttaatct acaccttttg tgtggatgtt tctgatgtaa
     3781 agctgctgtg aggctaaggt atgttgtttg tgttcaacat tctattcttc ttcggatatt
     3841 ttttttaaat gctactgaga ttctattgaa tagatgatta gagcacttag gaggtttgct
     3901 tcttttcata gtgtcaatta tttgtacgac tggatgataa tgatgaaaat atatctcttg
     3961 tggcaagtaa ctcaaaggtg taaaatgaat agtaaaaatt attttatttt ttattgacat
     4021 accctgatag atgttgtaga ctagtagcaa aaggcacttc taaaggtaag tgttctgagt
     4081 tgcctcagga gagggatggt atagctttat tttacaagga ggtatcatta gatttctatg
     4141 aactatttat tctgtacagt tttgtatatt tttggttcac aagataatta tacttgggtg
     4201 ccttttaaga aagttcaaga atactgctca cttcaataaa actaaatg
//
