LOCUS       NM_001134612            6908 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus SMC5-SMC6 complex localization factor 2 (Slf2),
            mRNA.
ACCESSION   NM_001134612 XM_001062922 XM_574673
VERSION     NM_001134612.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Raschle,M., Smeenk,G., Hansen,R.K., Temu,T., Oka,Y., Hein,M.Y.,
            Nagaraj,N., Long,D.T., Walter,J.C., Hofmann,K., Storchova,Z.,
            Cox,J., Bekker-Jensen,S., Mailand,N. and Mann,M.
  TITLE     DNA repair. Proteomics reveals dynamic assembly of repair complexes
            during bypass of DNA cross-links
  JOURNAL   Science 348 (6234), 1253671 (2015)
   PUBMED   25931565
REFERENCE   2  (bases 1 to 6908)
  AUTHORS   Alabert,C., Bukowski-Wills,J.C., Lee,S.B., Kustatscher,G.,
            Nakamura,K., de Lima Alves,F., Menard,P., Mejlvang,J.,
            Rappsilber,J. and Groth,A.
  TITLE     Nascent chromatin capture proteomics determines chromatin dynamics
            during DNA replication and identifies unknown fork components
  JOURNAL   Nat Cell Biol 16 (3), 281-293 (2014)
   PUBMED   24561620
REFERENCE   3  (bases 1 to 6908)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jun 1, 2021 this sequence version replaced NM_001134612.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-283               JAXUCZ010000001.1  253732030-253732312
            284-327             JAXUCZ010000001.1  253735168-253735211
            328-1061            JAXUCZ010000001.1  253735851-253736584
            1062-1116           JAXUCZ010000001.1  253739051-253739105
            1117-2084           JAXUCZ010000001.1  253743497-253744464
            2085-2155           JAXUCZ010000001.1  253745457-253745527
            2156-2278           JAXUCZ010000001.1  253749945-253750067
            2279-2446           JAXUCZ010000001.1  253750841-253751008
            2447-2549           JAXUCZ010000001.1  253753493-253753595
            2550-2625           JAXUCZ010000001.1  253763584-253763659
            2626-2767           JAXUCZ010000001.1  253769748-253769889
            2768-2870           JAXUCZ010000001.1  253776060-253776162
            2871-3047           JAXUCZ010000001.1  253776591-253776767
            3048-3145           JAXUCZ010000001.1  253778170-253778267
            3146-3233           JAXUCZ010000001.1  253782621-253782708
            3234-3365           JAXUCZ010000001.1  253784135-253784266
            3366-3474           JAXUCZ010000001.1  253785835-253785943
            3475-6908           JAXUCZ010000001.1  253791144-253794577
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..6908
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /note="SMC5-SMC6 complex localization factor 2"
                     /db_xref="GeneID:499360"
                     /db_xref="RGD:1560300"
     exon            1..283
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..3548
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /note="protein FAM178A; family with sequence similarity
                     178, member A"
                     /codon_start=1
                     /product="SMC5-SMC6 complex localization factor protein 2"
                     /protein_id="NP_001128084.1"
                     /db_xref="GeneID:499360"
                     /db_xref="RGD:1560300"
                     /translation="MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTTPAAAGKRTESP
                     GDRNQSIIDFFKPASKQDKHMLDSQKSDIKYRGNGLSITGTEQFERKLSSPKKPKPKR
                     MSSEESPILEAFMKGGKEHHKDRGVHESRRPCMSLSTKYLPKGAGIYAPSSYRLPKEI
                     KARKKKHRSPERRKSLFIHESNREKNDRDRGKNSEDSRKQVPATEGDIFKNSSRSVSS
                     RSSLSRHHPGESPLGARFQLSLASYCREREQKKLRKEQMEQRINSENSFSEASNLSLK
                     SSGVGKKCKPRHEHSKHNEAVPGKSNLSNLENGHLSRKRSSSDSWELSGSKQNKFSDK
                     RKRNSVDSDLKSTKEPVIPKAKESFLEKRPDTSHPREKFIRHIALKTPGGVLRLEDIA
                     KEPDDETDRSSADLAPSNSGHHSSKNSDQVHAASTKDTKTQKPHLPLPQEKSTAKRAS
                     NLQKSKPAGSVTSKETKLPLLSHVPSAVSSRVPLNAKNCTLPVLKKDKERSSSKERSG
                     HSAESSKHKEHKAKTIKAVSNESSGKSSGGSLHSEYAPPTASPPAALEVVPCVPSPAA
                     PSDKESSGNSNAGSSALKRKFRGDFDSDEESLGYNLESDEEEETLKSLEEIMALNFSQ
                     TPTASGKPPAFSKGLRPQSSDYMEYAQSGTYTNTLERLVKEKEDTQRLDELQKQLQED
                     IRQGRGIKSPIRIGDQDSTDDEDGLSEEHREFLKKFSVTVDAIPDHHPGEEIFNFLNS
                     GKIFNQYTLDLRDSGFIGESAVEKLILKSGKTDQIFLTTQGFLTTAYHYVQCPVPVLK
                     WLFRMMSVHTDCIVSVQILSTLMEITIRNDTFSDSPVWPWIPSLSDIAAVFFNMGVGF
                     GALFPLETLQPDFNEDSLISETQKTLGGKGSEDSSYNPVFSALPETNILNVVKFLGLC
                     TSIHPEGYQDGEIMLLILMLFKMSLEKELKQIPLVDFQSLLINLMKNIRDWNTKVHEL
                     CLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLVIISKLLDEKHEDIPNANNLQ
                     IPVLHRYLVQMKPSDLLKKMILKKKAEQPNETIDDSLHLDLEKQKHFVLLCGALEKHV
                     KCDIREDARLFYRTKVSILFVVEVTAAKIQNEKGLSKGITVGSSRC"
     exon            284..327
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            328..1061
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1116
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..2084
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2155
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2278
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2446
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2447..2549
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2625
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2626..2767
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2870
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3047
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            3048..3145
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            3146..3233
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3365
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3474
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
     exon            3475..6908
                     /gene="Slf2"
                     /gene_synonym="Fam178a; RGD1560300"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgaagagaga accgccatga agagagtagg gggtgccgcc cacctctgca ccgacagcct
       61 ccccgagtcc cagcagcaag acggcaacca cgcaaccagc ttctccagcc acagctcatg
      121 ccgccgtcgc cagcggcgcc gacatgacaa ggcgctgcat gcccgctagg ccaggtttcc
      181 cctcatcccc agccccgggg tcgtcgcccc cgcgctgcca tctgagaccc ggtagtacca
      241 cccctgctgc agcgggaaaa agaacagaga gtcctgggga caggaatcaa tcaatcatag
      301 atttcttcaa gccagcttca aaacaagaca aacatatgtt ggattcccaa aaatcagaca
      361 tcaaatacag aggaaatgga ttatccatca ctgggacaga gcaatttgaa aggaaattat
      421 cttcaccaaa aaaacctaaa cccaaaagga tgtcatcaga agaaagtcct attttagaag
      481 ctttcatgaa aggcgggaaa gagcaccaca aagaccgtgg cgtccatgag tcacgtcggc
      541 catgtatgtc tctaagcacc aaatatttac ccaaaggagc gggcatctat gctccttcct
      601 cttaccgatt gcccaaagag atcaaggcac ggaagaaaaa acaccggtct cctgagagaa
      661 ggaagtcact gttcattcat gaaagtaaca gggagaagaa tgacagagat cgaggcaaga
      721 acagtgaaga ctccagaaag caagtcccag ccacagaagg tgacatcttc aagaacagct
      781 ccagaagtgt tagtagcaga agcagcctat ctagacacca tccaggagaa agcccactgg
      841 gggctaggtt ccagttgtca ttagcttctt actgccgaga acgagaacag aagaagttga
      901 gaaaggaaca aatggagcag agaatcaact cagaaaattc tttctcagaa gcaagcaacc
      961 tttccttaaa gtcctctggt gtagggaaaa aatgtaagcc aaggcatgag cacagcaaac
     1021 acaatgaggc tgtacctggg aagagtaatc tctccaatct ggaaaatgga catctctcaa
     1081 gaaaaagatc atcttcagat tcgtgggaac tttcaggctc taaacagaat aaattctccg
     1141 acaaaagaaa aaggaactct gtggactcag acctgaaaag cacaaaagaa cctgtcatac
     1201 ctaaagcaaa agagtccttc ctagagaagc gcccagacac atcccatccg agagaaaagt
     1261 ttataagaca catcgcactg aagactcctg gtggtgttct gcgcttggaa gatatagcta
     1321 aggaacctga tgacgaaaca gatcgctctt ctgcagactt ggcaccttca aattctggcc
     1381 accattcttc caagaatagt gaccaagtcc acgcagcaag taccaaagac accaaaacac
     1441 agaagcccca cttgccttta cctcaggaaa aatccacagc taaaagagct agcaaccttc
     1501 agaaaagtaa accggctggt tctgtgacat caaaagagac aaagctacct ttactttccc
     1561 atgttccaag tgctgtttcc tctcgagtac cgctaaatgc taaaaattgc actcttccag
     1621 ttcttaaaaa agataaagag cgttcctcct cgaaagaacg ttctgggcat tctgcagaat
     1681 cctccaaaca caaggaacac aaagcaaaga ctatcaaggc tgtttctaat gaatcttcag
     1741 ggaaaagttc tgggggatcc ttgcattcag agtacgcccc tccaacagca tctcctccgg
     1801 ctgccttgga agttgtgccg tgtgtcccaa gcccagcagc tccttcagat aaagagagtt
     1861 caggaaattc caatgcaggt agcagtgcac tgaaaaggaa attcaggggt gattttgata
     1921 gtgatgaaga aagtttaggt tacaacttag agagtgatga ggaagaggaa acactaaaat
     1981 cactggaaga aataatggct ctgaacttca gtcagactcc tacagcttca ggaaagcctc
     2041 ctgcgttttc caaggggctt agaccccagt cgtcagacta catggaatat gctcagagtg
     2101 gaacttatac aaacacctta gagcgactgg taaaggagaa ggaagacaca cagaggctag
     2161 atgaactaca gaagcagcta caggaagaca taagacaggg ccgtggcatt aaatctccta
     2221 tcagaattgg cgaccaggac agtacagatg atgaggatgg cctctcagaa gaacacaggg
     2281 aatttctaaa gaaattttca gttacagttg atgctattcc tgatcatcat ccaggtgaag
     2341 aaatatttaa tttcctcaat tctggaaaaa ttttcaatca gtatacctta gatttaagag
     2401 actctggttt tatcggagaa agtgctgtgg aaaagcttat tctcaaatca ggaaaaacag
     2461 atcagatttt tttgacaaca caaggcttcc ttaccactgc ataccactac gtccaatgtc
     2521 ctgtacctgt gttaaagtgg ctgtttcgga tgatgtcggt tcacacagat tgtattgtgt
     2581 cagtgcagat tttaagtaca ttgatggaaa tcactattag aaatgatacg ttcagtgact
     2641 ctcccgtttg gccctggatc ccatcactgt ctgatatagc agctgtattc ttcaacatgg
     2701 gtgttggttt tggagctttg tttcctctgg agactcttca gccagacttt aatgaggaca
     2761 gtctaatttc tgaaacacag aaaacactgg ggggaaaagg aagtgaagat tcatcttata
     2821 atccagtatt ttcagctctt cctgaaacca acattttaaa tgtggttaag ttcctaggct
     2881 tatgtacatc tatacatcca gaaggttacc aagatggaga aataatgttg ctgattttaa
     2941 tgctgtttaa aatgagtttg gaaaaagagc ttaaacagat tccattagta gactttcaga
     3001 gcctcctgat aaatctcatg aaaaatatca gagattggaa cacaaaggtt catgaactct
     3061 gtttgggcat aaatgaactt tccagccatc cccataacct tctgtggttg gtacagctag
     3121 tccctaactg gacatctcgt ggaaggcagc tgaggcagtg cctcagtctg gtgattattt
     3181 caaagctttt ggatgaaaaa catgaagata ttcctaatgc caataatctt cagatcccag
     3241 tcctacatcg ctatctagta cagatgaagc cttctgattt gttgaagaaa atgatcttga
     3301 agaaaaaggc cgaacagccc aatgaaacca tcgatgacag tcttcattta gaccttgaaa
     3361 agcagaaaca cttcgtgctg ctttgtgggg ctttggaaaa gcatgttaag tgtgatatta
     3421 gggaagatgc aagacttttc tacagaacta aagtaagtat attatttgtg gtagaagtta
     3481 cagcagcaaa aatacaaaac gagaagggcc tttccaaggg gattactgtg ggatccagca
     3541 gatgctaagg aacacggctg tgtgcatatg cagtgtgagg ctggtgatga agactttccc
     3601 gtttctgaag gagatacgaa gtgccatctg cagctgcctg tagaggaaag gggggagggt
     3661 ggaagcagct ggtagctgcg gacccagcct gcccctccta gcacctccac ctcctgctaa
     3721 gtcttcagca gttatcgtgt aaggggctgc atagcacttg gatcatcaga aagtcaggaa
     3781 gaaaagtgcg ggccagcctg agatggacgc agaacggaag gttcagctgc ttttcatttt
     3841 ccttttggtt attctagggt ggaaagggaa ggctcagaac agagccctat aattagaagt
     3901 gttggtctct tctaaaaacc cataaaccat aggcagtttc agcccatata tatcctttag
     3961 tattcaagat tataaatctg agatttttaa atatatttaa aatcaaggaa cagacatctg
     4021 gtatattgtc agactgccct tagaggaaga gattaagcta caacatagtg actgttttta
     4081 aaatgccaga acattcacag gcagtttgtt tagggtttct tgtaatgcat atatttttaa
     4141 atactggttt aatcataaaa tctcagctaa gctagaattc tggccattgg taactatatt
     4201 acagaagtct ctatataaag gcttaacaat ctggaagttt ccaaaatcct tgtttccaca
     4261 agtatataat ttagcagagg ccttgatggt gtttattttg gggacgtgtg tgtgtgtgtg
     4321 tgtgtgtgtg tgtgtgtgtg tgtgtgtgta caggtgcacg tgtatgcgtg ctcatggcac
     4381 actcaagtct gtatcttgaa gttgttgcac ttgaaaacca cagctgctct aaattctttg
     4441 aaacactgga aagccatcct ttagtttaga tgtagaggtt agcagaggcg cacatgctag
     4501 gttgagcctt actccctttg aagactttgg tagcgacact cctgccgact gctgtcagtt
     4561 tgcagagttt gcttcctaaa aaggatgcca actgcttatt ctttgaatgt tggctggagc
     4621 ggcttgctgt ctcctgagca tgctaatgtc tgtgtgggtc caggggagag gggtggagaa
     4681 gggaactggg ctcagtgtta tggtttgaga ggagaaaata agttctgaga gctaactttc
     4741 tacctctaaa ctgaggctta ggaataaaaa ccattttatc ttaaatccat catttaaaat
     4801 agcgttagca actttagagc tcgtgtcaag cattgggcag ttagagattc tatagggaaa
     4861 actacacaaa tcacattttc aagaattaag gctgatccag gctccaagag tcagaccaac
     4921 aaaagtttta ttctgtgttg agtttactgg taagaatatt gtcttgatgc tacctctcaa
     4981 gggtattgtt acaaatgcca ctatggttaa agagatagat acgaagagtt atatttgact
     5041 gaagcttgaa actctggcat ctatctgccc aacagtgggg ctttcactct gtaatttaat
     5101 accttgtaga tacattattt gtgtgtaatt ttataagtgt tcatattttt ctcattttgc
     5161 attgtgtaaa gtgtacaaaa tctcaaagta taaaaatctg cttatattgc ttgtaattac
     5221 agtgtgtaaa tattttctat tgtgtacatt gacggggaca agtgggttat tcaggttttt
     5281 aagtgatcct tttatattgc agtttcaacc aataaccacc catcaaattt aaaaccactt
     5341 tgatacattc ttatttagca gttccaataa gaataaaatc tctattttca attgtctttc
     5401 tccattagag aaaattactt tatctgtccc tttaaaataa atggccagac atcagttcag
     5461 gcctttgtat ttatgactct ggtagcagtc ttcagtctcc aggtcatagt ccagtcagta
     5521 tttacattta ggttctcgta gaaatgttgt gattctattt tagcacaagt agctcatggt
     5581 ttctcccaaa tcaagtattt tccatctcct tctgagtccc catgcgttgt ctccctctgc
     5641 ctgttgttgc ccagaaaatg ggacggtgag gagggaggag atgcttgttg cacagagact
     5701 gtcaggccat gtgtgggact tggcaaacaa agcttgcact gagtggtggt gtgtttggca
     5761 atattactgt gccaaaaata atccttgtct acttttctgg atgtgtatgt caaacttttt
     5821 acccttactg caagctgaaa attaaagttc ttgtgtttat gcttttgtgt gtaactgcct
     5881 tttctgacct gcttttcttg ttacctgaaa atacagttct gtaattcgtg ttaaatgaag
     5941 aggctttttg tgcacaaaat cacctgtgta gcactgaagt cagtgtttgt gcattgtttt
     6001 gtctgtgtcc tgatggcaac ggtgcctttg tcacctttca gaaggttggc tttttttttt
     6061 ttttaatgca agtagtagct tgcttttgac ttcacaaaaa aaagaaagaa agaaaaagaa
     6121 agaaagaaag aaagaaagaa agaaagaaag aaagaaagaa agaaagaagg aaagaaagaa
     6181 ggaaagaaag aaggaaagaa agaaagagga acaaagaaat atatacatat ctccctggta
     6241 atgatagata agatagttac cacccaggcg ctgttgaagc atttgggggt tttttgtttg
     6301 ttttttgttt tgtatttttt tctccccctc tccctccaat cagaatagat agagttggtg
     6361 gggtcagtaa taatgtgtgg agtcttgaaa ccaggaggat ttttaaattt aaaacctgac
     6421 tcattgacaa gcagctgagt tggaggactt acttggcttg tctctcagga ggcaggggta
     6481 aggtatagtt gggtgcgaga gtcagcaaaa ttcgatcttt tgaggacgcc tactctatgg
     6541 tgcaggtgca cctcatctgt gcctcagttt ccccggggca ttcttgtcag ccagttaatc
     6601 tactagctct taggcagtaa atgcaatggt tttttctttc ctttaaaatt ttatactgtc
     6661 ttgtttaaaa gtcttctgaa tgtatgtgta tgtgttatta aaactttttc tcagcttaaa
     6721 cgtgtcttgt aacatttgat tgagtagtag aggtggttga gtatcgaaaa taccctgttt
     6781 gaagcttttt tccctttagc ttgatgcctt ttttgtatct gtggaaaaca aagccacagt
     6841 tctccacagt tcatgtttac ataacgcaat taataaattt actgtgtact ttacagtcag
     6901 gaatttaa
//
