LOCUS       NM_133608               2995 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus solute carrier organic anion transporter family,
            member 4a1 (Slco4a1), mRNA.
ACCESSION   NM_133608
VERSION     NM_133608.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Fujiwara,K., Adachi,H., Nishio,T., Unno,M., Tokui,T., Okabe,M.,
            Onogawa,T., Suzuki,T., Asano,N., Tanemoto,M., Seki,M., Shiiba,K.,
            Suzuki,M., Kondo,Y., Nunoki,K., Shimosegawa,T., Iinuma,K., Ito,S.,
            Matsuno,S. and Abe,T.
  TITLE     Identification of thyroid hormone transporters in humans: different
            molecules are involved in a tissue-specific manner
  JOURNAL   Endocrinology 142 (5), 2005-2012 (2001)
   PUBMED   11316767
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097285.1.
            
            On Jun 12, 2005 this sequence version replaced NM_133608.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097285.1, BC097286.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132307, SAMD00155322
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..2995
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /note="solute carrier organic anion transporter family,
                     member 4a1"
                     /db_xref="GeneID:171144"
                     /db_xref="RGD:620228"
     exon            1..80
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            81..977
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..2338
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /note="solute carrier family 21 member 12; organic
                     anion-transporting polypeptide E; sodium-independent
                     organic anion transporter E; solute carrier family 21
                     (organic anion transporter), member 12"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 4A1"
                     /protein_id="NP_598292.2"
                     /db_xref="GeneID:171144"
                     /db_xref="RGD:620228"
                     /translation="MPQHAMGDKHFLSLPKHLFTSTSSTTDSGCDTPPSSRASPASLR
                     SAHGALGSSSQPLFEPQVEKRSSQAAREVQYLSSGPQSTLCGWQSFTPKCLQVFNTPK
                     GFLFFLCAASFLQGMTVNGFINTVITSIERRFDLHSYQSGLIASSYDIAACLCLTFVS
                     YFGGNGHKPRWLGWGALVLGIGSLVFALPHFTAGRYEVEIDDEGLGTETGTCLTNQSQ
                     VECKDRASGLSSYRLIFMLGQLLHGVGATPLYTLGVTYLDENVKSSYSPIYIAIFYTA
                     AILGPAAGYLIGGAMLNVYTEVGQRTELTTDSPLWVGAWWIGFLGAGIAAFLIAIPIL
                     GYPRQLPGSQRYVVMRAAETQQLKDHSRDNPAFGKTVRDLPLSVWILLRNPTFILLCL
                     AGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGYLVVPAGGGGTLLGGFLVNKFK
                     LRGSGIIRFCLFCTLTSLLAFFVFLMHCPNVHMAGVTTGYVGSLLPKGQLDLKAACNA
                     LYCCQPRHYSPLCGSDGTMYYSPCYAGCPEGAVTGPGGQKVYRGCSCILEKASSGWGN
                     ATAGKCASTCQSKPLLLVLVFVVIIFTFLSSIPALTATLRCVCDRQRSFALGIQWIVV
                     RTLGSIPGPIAFGWVIDKACLLWQDQCGHQGSCFVYKNEAMSRYLLIAGLTFKVLGFL
                     FFVAAYFLYKSPSVSSDGLEASLPSQSSASDSPTEQLQSNV"
     exon            978..1068
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1190
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1293
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1448
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1644
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1810
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1811..1983
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2048
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2197
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2966
                     /gene="Slco4a1"
                     /gene_synonym="OATP-E; Slc21a12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgatgaa tgaagggcga gtgggctgcg cgcgaaggcc agagtgcagg gtgcagcacg
       61 gcggccgggt tcgcgggaag ggtgacccag tgacaagcca gtctctcggc cacctctact
      121 gcatttcacc gactctgttg tcaaagcctt ccccacgagg ctggagatgc ctcagcacgc
      181 aatgggggac aagcatttcc tctccctccc gaagcacctc tttaccagca cgtcctcgac
      241 cacggatagc gggtgcgaca ctccacccag cagcagagcg tccccagcct ccctgcgctc
      301 tgcccacggc gccctgggct cctccagcca acctctgttt gagccccagg ttgagaaacg
      361 gagcagccaa gcagcccgtg aggtgcaata cctgtcttcg gggccacaga gcacgctgtg
      421 cggctggcag tccttcactc ccaagtgcct gcaggtcttc aacaccccca agggcttcct
      481 cttcttcctg tgtgccgcct ccttccttca gggtatgaca gtgaacggct ttatcaatac
      541 cgtcatcacc tccattgaac gtcgcttcga tctgcacagc taccagagcg ggctcattgc
      601 cagctcctat gacatcgccg cctgtctttg ccttaccttc gtcagctact ttgggggcaa
      661 cggacacaaa ccgcgctggc tgggctgggg tgcgctggtc ctaggaattg gctccttggt
      721 attcgctctg ccccatttca cggctggccg ctacgaggta gagatagacg acgaggggct
      781 ggggaccgag actgggacgt gcctgactaa tcagagccag gtggagtgta aagacagggc
      841 ctcaggcctg tctagctacc ggctgatctt catgctgggc cagctcctgc acggcgtggg
      901 tgccacaccg ctctacacgc tgggtgtcac gtatctggat gagaacgtca agtcgagcta
      961 ttcgcccatc tatattgcca tcttctacac agcagccatc ctcggacctg cggcaggtta
     1021 cctgattgga ggagccatgc taaatgttta cacagaagtg ggccaacgga cggagctgac
     1081 cactgacagc ccactgtggg ttggtgcctg gtggatcggc ttcctgggag ctggaattgc
     1141 tgcgttcctt attgccatcc ccattcttgg ctatccccgg cagctaccag gctcccagcg
     1201 ctatgtcgtt atgagagcag ccgaaacaca gcagctcaaa gaccacagcc gagacaatcc
     1261 agcttttggc aagactgtca gagacctgcc cctctccgtc tggatccttc tgagaaaccc
     1321 cacattcatc ctgctctgcc tggcaggggc caccgaagcc acactcattg ccggcatgtc
     1381 cacatttggc cccaagttct tcgaggccca gttcagcttg agtgcctccg aggctgccac
     1441 cctgttcgga tatctggtgg tgccagcagg cggcggcggc acactcctag gtggcttcct
     1501 ggtgaacaag ttcaaactcc gtggctctgg gatcatcagg ttctgcctgt tctgcacctt
     1561 gaccagtcta ctggcctttt ttgtcttcct catgcactgc cccaatgtgc acatggcagg
     1621 tgtgacaact ggctatgttg ggagcctcct gcctaaggga cagctggacc tgaaggcggc
     1681 ttgcaacgcc ctctactgtt gccagccgag gcactacagc cccctgtgtg gctccgacgg
     1741 cactatgtac tactctccct gctatgcagg ctgccccgaa ggtgctgtga ccggcccggg
     1801 tggccagaag gtataccgag gctgtagctg tatccttgag aaggcttcct ctggctgggg
     1861 caatgctacc gcagggaagt gcgcttccac ttgtcagagc aagcccctcc ttctggttct
     1921 cgtgttcgtt gtaattatct ttacattcct cagcagcatt cccgcgctaa ctgctactct
     1981 acgatgtgtc tgtgatcggc agaggtcctt tgccctgggg atccagtgga tcgtcgttag
     2041 aacgctaggc agtatcccag ggcccattgc ctttggctgg gtgattgaca aggcctgcct
     2101 gctgtggcaa gaccagtgtg gtcatcaggg ctcctgcttc gtgtacaaga atgaagccat
     2161 gagtcggtac ctgctcattg caggactcac tttcaaggta ttaggcttcc tcttctttgt
     2221 cgctgcctac tttctctaca agtccccttc agtgtcctca gacggcctgg aggcctccct
     2281 gcccagccag tcctcagcct ctgacagccc cacagaacag ctccagagca acgtctgaca
     2341 caggtggctc ctccacattt cctgaggact ctccctggaa accctgaccc accctcacag
     2401 gatagtaaca ctcatgacct tgcaaaacct cacactgtgt tctgggacct cgagccgccc
     2461 cacaccgtga ctgaacagcc ttcagagact ttaaggagga agtcacgtgg gttgtgtatg
     2521 ggtcatgtat gaaccagaca catttcccaa atcctggagt ctcttaagtg gtcactacat
     2581 ttcatagacc gtaacctggt tctgacttcc ggcgtctact aagaagcccc gtgcagggca
     2641 agccctgtgc agggcagcag tgccctgggc atgatcctgt ggaaccagat agttggtgtt
     2701 ttgcttgaat ctacttaact gcctgtcctg gaagcctggt ggcctccgtg tggggtggga
     2761 gcaacttgaa tcattatgtc cggacgtctg ttttgcactg aatggtgttt atggaatcag
     2821 ttttgtacct gatcatgtga ctcatgtcca agcaaactgc agtgaggaca tgatcccatc
     2881 tgaggtgcca tgtggcttgc atggacaatg tgtttctatg tttttggtta caatatgtat
     2941 ataatatatt ttaatattta aaccaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
