LOCUS       NM_177481               2811 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus solute carrier organic anion transporter family,
            member 3a1 (Slco3a1), mRNA.
ACCESSION   NM_177481
VERSION     NM_177481.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Wei,S.C., Tan,Y.Y., Weng,M.T., Lai,L.C., Hsiao,J.H., Chuang,E.Y.,
            Shun,C.T., Wu,D.C., Kao,A.W., Chuang,C.S., Ni,Y.H., Shieh,M.J.,
            Tung,C.C., Chen,Y., Wang,C.Y., Xavier,R.J., Podolsky,D.K. and
            Wong,J.M.
  TITLE     SLCO3A1, A novel crohn's disease-associated gene, regulates
            nf-kappaB activity and associates with intestinal perforation
  JOURNAL   PLoS One 9 (6), e100515 (2014)
   PUBMED   24945726
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2811)
  AUTHORS   Kindla,J., Rau,T.T., Jung,R., Fasching,P.A., Strick,R., Stoehr,R.,
            Hartmann,A., Fromm,M.F. and Konig,J.
  TITLE     Expression and localization of the uptake transporters OATP2B1,
            OATP3A1 and OATP5A1 in non-malignant and malignant breast tissue
  JOURNAL   Cancer Biol Ther 11 (6), 584-591 (2011)
   PUBMED   21278488
REFERENCE   3  (bases 1 to 2811)
  AUTHORS   Adachi,H., Suzuki,T., Abe,M., Asano,N., Mizutamari,H., Tanemoto,M.,
            Nishio,T., Onogawa,T., Toyohara,T., Kasai,S., Satoh,F., Suzuki,M.,
            Tokui,T., Unno,M., Shimosegawa,T., Matsuno,S., Ito,S. and Abe,T.
  TITLE     Molecular characterization of human and rat organic anion
            transporter OATP-D
  JOURNAL   Am J Physiol Renal Physiol 285 (6), F1188-F1197 (2003)
   PUBMED   14631946
  REMARK    GeneRIF: plays an important role in translocating prostaglandins in
            specialized tissues and cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1 and AF239219.1.
            
            On Oct 11, 2022 this sequence version replaced NM_177481.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.2231.1,
                                           SRR21887623.1103577.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-336               JAXUCZ010000001.1  137797501-137797836 c
            337-802             JAXUCZ010000001.1  137741757-137742222 c
            803-901             AF239219.1         647-745
            902-1165            JAXUCZ010000001.1  137585272-137585535 c
            1166-1330           JAXUCZ010000001.1  137569024-137569188 c
            1331-1529           JAXUCZ010000001.1  137561388-137561586 c
            1530-1668           JAXUCZ010000001.1  137559726-137559864 c
            1669-1844           JAXUCZ010000001.1  137543880-137544055 c
            1845-1909           JAXUCZ010000001.1  137538396-137538460 c
            1910-2152           JAXUCZ010000001.1  137525126-137525368 c
            2153-2811           JAXUCZ010000001.1  137516037-137516695 c
FEATURES             Location/Qualifiers
     source          1..2811
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2811
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /note="solute carrier organic anion transporter family,
                     member 3a1"
                     /db_xref="GeneID:140915"
                     /db_xref="RGD:620227"
     exon            1..336
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..2235
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /note="OATP-D; solute carrier family 21 member 11;
                     prostaglandin transporter subtype 2; organic
                     anion-transporting polypeptide D; sodium-independent
                     organic anion transporter D; solute carrier family 21
                     (organic anion transporter), member 11"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 3A1"
                     /protein_id="NP_803434.2"
                     /db_xref="GeneID:140915"
                     /db_xref="RGD:620227"
                     /translation="MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLV
                     SECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGAR
                     GHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCATNGSSSDEG
                     PDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGIL
                     FTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLF
                     FSSLLMFGFPQSLPPHSEPGMESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQ
                     LRVIPKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLG
                     MTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAG
                     VTVRYGNNSARGSPLDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG
                     CACLTTVPPENATVVPGKCPSPGCQEAFLTFLCVMCVCSLIGAMAQTPSVIILIRTVS
                     PELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRY
                     LYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQDIETEKTCPESQ
                     SPSEDSFVRS"
     exon            337..802
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            803..901
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1165
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1330
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1529
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1668
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1844
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..1909
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2152
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2811
                     /gene="Slco3a1"
                     /gene_synonym="Slc21a11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accctctcta gccgcggcag gacgggggcg gccgccgcgg gcccggggcg gggacagtac
       61 gcagcctcgc ggcacgcacc cccacccagc aacggccacg acacccgggg cgagcgggaa
      121 agcggcggcg gcggcggcgg cggcggcggg ggaaggatgc agggaaagaa gccgggcggc
      181 tcgtcgggcg gcggccggag cggcgagctg cagggggacg aggcgcagag gaacaagaag
      241 aagaaaaaga aggtgtcctg cttctccaac atcaagatct tcctggtgtc tgagtgcgcc
      301 ttgatgctgg cgcagggcac ggtgggcgcc tacctggtga gcgtgttgac caccctggaa
      361 cgcaggttca accttcagag cgccgatgtg ggtgtgatcg ccagcagctt tgagatcggc
      421 aacctggcgc tgattctctt cgtgagctac ttcggagcac gtgggcaccg accacgcctc
      481 atcggctgtg gtggaatcgt catggcgttg ggtgcgctgc tctcggcact gcctgaattc
      541 cttacccacc agtacaagta tgaggctggt gagattcgat ggggagccga aggccgcgat
      601 gtttgtgcca ccaatgggtc cagcagcgat gaggggcctg acccggactt aatctgccgt
      661 aaccggacag ccacgaacat gatgtacttg ctgctcattg gggctcaggt gctcctgggc
      721 atcggtgcta cccccgtgca acccctgggg gtctcctaca ttgacgacca cgtgcggagg
      781 aaggactcct cgctctacat aggaatcctg ttcacgatgt tggtatttgg accagcctgt
      841 ggatttattc tgggctcttt ctgtaccaaa atctacgtgg acgcggtctt cattgacaca
      901 agcaacctgg acatcactcc tgacgacccg cgctggatcg gagcctggtg gggcggcttc
      961 ctgctctgtg gtgccttact cttcttctcc tccctcctga tgtttggctt cccacagtcc
     1021 ctgcccccac actcagagcc cggcatggag agtgagcagg ccatgctccc agaaagagaa
     1081 tatgagaggc ccaagcccag caatggagtc ctgagacatc ccctggagcc ggacagcagt
     1141 gcctcctgtt tccaacaact gagagtgatt cccaaggtca ccaagcacct gctctcaaac
     1201 cctgtgttca cctgcatcgt cctggctgct tgcatggaga ttgctgtggt ggccggcttc
     1261 gctgccttcc tgggcaagta cctggaacag cagtttaacc tcaccacttc ctctgccaac
     1321 cagctgctcg ggatgacagc aatcccctgt gcctgcctgg gcatctttct gggtggcctt
     1381 ttggtgaaga agctgagcct gtctgctctg ggggccattc ggatggccat gctggtcaac
     1441 ctggtgtcca cagcctgcta cgtctccttc ctcttcctgg gctgtgacac aggccctgtg
     1501 gccggggtca ctgttcgcta tggaaacaat tcagcacgtg gctcgcccct tgacccctac
     1561 tctccgtgca acaacaactg tgaatgccag acagattcct tcacgccagt gtgcggggcc
     1621 gatggcatca cctatctgtc agcctgcttc gccggctgca atagcacgaa cctcacaggc
     1681 tgtgcgtgcc tcaccaccgt cccccctgag aatgccaccg tggttcctgg aaaatgtccc
     1741 agtcctgggt gccaagaggc cttcctaacc ttcctctgtg tgatgtgtgt gtgcagcctg
     1801 atcggggcca tggcgcaaac cccttctgtc atcatcctca tcaggacagt cagccctgaa
     1861 ctcaagtctt acgcgctggg agttcttttt ctgctccttc gtttgttggg tttcatcccc
     1921 ccacccctca tcttcggggc cggcatcgac tccacctgtc tgttctggag caccttctgc
     1981 ggggaacagg gcgcctgtgt cctctatgac aacgtggtct acagatacct gtacgtcagc
     2041 atcgccattg cactcaaatc cttcgccttc atcctctaca ccaccacgtg gcagtgcctg
     2101 cggaaaaact ataaacgcta catcaaaaac cacgagggcg ggctgagcac cagcacagag
     2161 tatcaagaca ttgagacaga gaaaacctgc cctgagtcac agtcgccttc agaagactcc
     2221 tttgtgcgaa gctgaggtct actctcttac agcagagacc accaccatca tcactaccac
     2281 caccaccacc acccacagac ctcaaggcct gacagccctg tgctgtccgg gaacctaagg
     2341 gttcctatgt ggattagccg atatgtggtc ctttgaggct tcaagcacag gcctgtgaca
     2401 aggactaagg aggtggcata tggtcagctg cccttcaaag tgggcatcaa tcctaaaatg
     2461 caaggttgaa attgatgtgc aaattacctt tggcctatcc ctcttctcgc ttctgtgggg
     2521 atggctttct gacacgcttt agaaaacccc ctctggggat gcttctctga ccaaacactc
     2581 ttaaccgttc caaagaaatc agcagaggct gagctttagc aaaaagggtg taaaaaaatc
     2641 cagattccca gaagagagga ggaagaaaag cacacactta atagattctg agcgcgcgcg
     2701 gtagtcagta tttttgcagc ttatattttc cagatgagca gtttagagat acatgatata
     2761 aagtgtatac tgtacatttg ctgaaattat attaaaagca ctattttaat t
//
