LOCUS       NM_130736               2478 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier organic anion transporter family,
            member 1a6 (Slco1a6), mRNA.
ACCESSION   NM_130736
VERSION     NM_130736.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2478)
  AUTHORS   Dransfeld,O., Gehrmann,T., Kohrer,K., Kircheis,G., Holneicher,C.,
            Haussinger,D. and Wettstein,M.
  TITLE     Oligonucleotide microarray analysis of differential transporter
            regulation in the regenerating rat liver
  JOURNAL   Liver Int 25 (6), 1243-1258 (2005)
   PUBMED   16343078
REFERENCE   2  (bases 1 to 2478)
  AUTHORS   Hagenbuch,B., Gao,B. and Meier,P.J.
  TITLE     Transport of xenobiotics across the blood-brain barrier
  JOURNAL   News Physiol Sci 17, 231-234 (2002)
   PUBMED   12433976
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF053317.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF053317.2 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2478
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..2478
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /note="solute carrier organic anion transporter family,
                     member 1a6"
                     /db_xref="GeneID:84608"
                     /db_xref="RGD:69304"
     exon            1..91
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..2044
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /note="kidney-specific organic anion transporting
                     polypeptide 5; OATP-5; solute carrier family 21 member 13;
                     solute carrier family (organic anion transporter) member
                     13"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 1A6"
                     /protein_id="NP_570092.1"
                     /db_xref="GeneID:84608"
                     /db_xref="RGD:69304"
                     /translation="MGEPEKRAGTHGIRCFAKIKVFLLALTWAYASKALSATYMNSML
                     TQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKRHRPIMIGIGCAVMGLGCFI
                     ISLPHFLMGRYEYETTISPTSNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWIY
                     VLVGNIIRGIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCA
                     TIYVDMGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPE
                     DMANETKNDEGDKHREKAKEEKRGITKDFFLFMKSLSCNPIYMLCVLTSVLQVNGFVS
                     IFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKITLKKAAFISY
                     CLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNTRCSCLTKTW
                     DPVCGDNGLAYITPCLAGCEKSVGSGINMVLQDCSCIQSSGNSSAVLGLCNKGPDCAN
                     KLQYFLIITVFCSFFYSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRILGGILAPIY
                     FGVLIDRTCLHWGTQKCGEPGACRTYEINSFRSIYLGLPAALRGSSYLPAFFILRLMR
                     KFQFPGDINSPVTDHVEMMLTEKESEHTDVHRSPQVENDGELKTKL"
     exon            92..233
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            234..366
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            367..473
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            474..620
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            621..719
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            720..941
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1106
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1302
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1468
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1641
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1706
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1824
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..2478
                     /gene="Slco1a6"
                     /gene_synonym="Oatp5; Slc21a13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagacatcc tcaaccaatc agaagaacaa aatgggagag cctgagaaaa gggctggaac
       61 ccacgggatc agatgctttg ccaagataaa ggtgtttctg ttggcgttaa catgggcata
      121 tgcgtccaaa gcactatcag caacttacat gaattccatg ctcacacaaa tagagaggcg
      181 attcaatatt tccacatcta tagttgggct tatcaatggg agctttgagg taggaaacct
      241 cttgttgatt atattcgtga gttattttgg acggaaacgg cacagaccta tcatgattgg
      301 cattggatgt gcagtcatgg gcctaggatg cttcataatc tcactacctc atttcctcat
      361 gggccgatac gaatatgaaa caacaatttc acctacaagc aacttgtcct caaacagctt
      421 cttgtgtatg gagaaccgaa cacagacctt aaagccaaca caagacccag cagagtgtgt
      481 gaaagaaatg aaatcattaa tgtggatata tgtactggta ggaaacatta tacgtggaat
      541 tggtgaaact cccatcatgc ctttgggtat ttcctacata gaagactttg ccaaatcaga
      601 aaactctccc ttttacattg ggattttaga agttggaaag ataactggcc caatagctgc
      661 aatttggttg ggatctttct gtgcaaccat ttatgtagac atggggtctg tgaatacaga
      721 tgacctgacc ataactccca cagatacacg ctgtgttggt gcttggtgga tcggcttttt
      781 ggtctgtgca ggattgaata tcttgatcag catccccttt ttcttctttc ccaaaacatt
      841 cccaaaggaa ggaccagagg atatggccaa tgaaactaaa aatgacgaag gagataaaca
      901 cagagaaaaa gccaaagaag aaaaaagggg aatcacaaaa gatttctttc ttttcatgaa
      961 gagcctctcc tgcaatccta tttacatgct ttgcgtcctt acaagtgtgc tccaggtaaa
     1021 tggatttgtc agtattttta ctttcaagcc taaatacctg gaacatcatt atggaaaatc
     1081 cagttcagag gcaatcttcc tcatgggtct ttatacctta ccttcagtat gtgttggata
     1141 tttaattagt ggctttatta tgaagaagtt caagattact ctcaagaaag cagcattcat
     1201 atcgtactgc ctaggcatgt ccgagtgcct tctgtccctc tgtaacttta tgctaacctg
     1261 tgataacgtc ccaattgctg gcttaactac ttcttatgaa ggaattcagc agtcttttga
     1321 tatggagaat acggtcctgg ccgactgcaa cacaaggtgc agctgcttaa caaaaacatg
     1381 ggatccagtg tgtggagaca atggcctagc atacataaca ccttgccttg caggctgtga
     1441 gaagtcagtt ggatcaggaa tcaacatggt gcttcaggat tgcagctgca ttcagtcatc
     1501 aggaaactcg tctgcagtcc tcgggctgtg taacaagggt cctgattgtg ccaacaagct
     1561 acagtacttc ttaatcataa cggtgttttg ttccttcttc tactcattat cactcatacc
     1621 tgggtacatg atttttctga ggtgtatgaa gtctgaagaa aagtcacttg gaattggact
     1681 acaggcattt tgcatgagaa tattgggtgg cattctggca cccatttact ttggagtttt
     1741 gatagacaga acctgtttac attggggaac tcagaaatgc ggtgagcctg gggcatgcag
     1801 gacgtatgaa ataaatagct tcaggagcat ttaccttgga ttgcctgcag ctctaagagg
     1861 atcaagctat ctgcctgcct tcttcattct aagacttatg aggaaattcc agttccccgg
     1921 ggacatcaac tctccagtaa ctgatcatgt ggagatgatg ctcacagaga aggaaagcga
     1981 gcacacagat gtgcacagaa gtcctcaggt cgagaatgat ggagaactga aaacgaagct
     2041 gtaatgagtt ttctactgcc ctgttcaagg ccatgaacag aatgcacact tcccttcctc
     2101 ggaatcccga gagatacaat aggaaccttc tctttaagga cctcaatgat tatttttctc
     2161 actataaaaa taattgctga tatcactttc agaacttcag ggtgatattt aagatttccc
     2221 cgggaaagac ttttatggtg acccccacac tacactttaa agcttccttc attttcacat
     2281 aacattttct cttaactcaa tcaagggaag tatgtgtttc ccacacagct tcaaatgagt
     2341 ttaaaacttt cctattccag aaacactatt taatttcact gaatttaaat ttccatactg
     2401 ggggtaatta gaactgaaaa tatgccccct ggttgtgtca tactgaaata aattgttcaa
     2461 attcattctt tctatgtg
//
