LOCUS       NM_001173973            2254 bp    mRNA    linear   ROD 15-AUG-2024
DEFINITION  Rattus norvegicus solute carrier family 9 member B1 (Slc9b1), mRNA.
ACCESSION   NM_001173973 XM_001077752 XM_345293
VERSION     NM_001173973.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2254)
  AUTHORS   Chen,S.R., Chen,M., Deng,S.L., Hao,X.X., Wang,X.X. and Liu,Y.X.
  TITLE     Sodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and
            male fertility
  JOURNAL   Cell Death Dis 7 (3), e2152 (2016)
   PUBMED   27010853
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2254)
  AUTHORS   Liu,T., Huang,J.C., Zuo,W.L., Lu,C.L., Chen,M., Zhang,X.S.,
            Li,Y.C., Cai,H., Zhou,W.L., Hu,Z.Y., Gao,F. and Liu,Y.X.
  TITLE     A novel testis-specific Na+/H+ exchanger is involved in sperm
            motility and fertility
  JOURNAL   Front Biosci (Elite Ed) 2 (2), 566-581 (2010)
   PUBMED   20036903
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_345293.4, XM_001077752.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.537849.1,
                                           SRR26360181.1975389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                JAXUCZ010000002.1  226442892-226442984
            94-519              JAXUCZ010000002.1  226443184-226443609
            520-580             JAXUCZ010000002.1  226450541-226450601
            581-740             JAXUCZ010000002.1  226450888-226451047
            741-911             JAXUCZ010000002.1  226464725-226464895
            912-1054            JAXUCZ010000002.1  226466226-226466368
            1055-1182           JAXUCZ010000002.1  226467307-226467434
            1183-1358           JAXUCZ010000002.1  226470267-226470442
            1359-1465           JAXUCZ010000002.1  226484563-226484669
            1466-1615           JAXUCZ010000002.1  226485776-226485925
            1616-1724           JAXUCZ010000002.1  226487818-226487926
            1725-1861           JAXUCZ010000002.1  226488736-226488872
            1862-2254           JAXUCZ010000002.1  226491549-226491941
FEATURES             Location/Qualifiers
     source          1..2254
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q43"
     gene            1..2254
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /note="solute carrier family 9 member B1"
                     /db_xref="GeneID:365946"
                     /db_xref="RGD:1305087"
     exon            1..93
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            94..519
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     CDS             515..2074
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /note="Na+/H+ exchanger domain containing 2; Na+/H+
                     exchanger domain containing 1; solute carrier family 9,
                     subfamily B (cation proton antiporter 2), member 1; solute
                     carrier family 9, subfamily B (NHA1, cation proton
                     antiporter 1), member 1"
                     /codon_start=1
                     /product="sodium/hydrogen exchanger 9B1"
                     /protein_id="NP_001167444.1"
                     /db_xref="GeneID:365946"
                     /db_xref="RGD:1305087"
                     /translation="MSESNIEVDKKDDHLQSSITDQAPEEPEPKVPQMKESKMKETQT
                     TKIETEEWEREHSSTSSFCPPQGTVNKTITDGVTLIVLWILLWALIGQEVLPGGNLFG
                     LVVIFYSAFLGGKIIEVIRIPVVPPLPPLLGMLLAGFTIRNVPILYKFVHIPTSWSSA
                     LRNTALTIILIRAGLGLDPQALKHLKGVCLRLSFGPCLLEACSAALFSHFIMNFPWQW
                     GFLLGFVLGAVSPAVVVPNMLLLQENGYGVEKGIPTLLVAASSMDDIVAITGFNTFLS
                     IVFSSGSVISNILSSLRDVLIGVLVGVVMGIFVQYFPSRDQERLTQRRAFLVLSMCVS
                     AVLGCQHIGLHGSGGLVTLVLSFMAAKRWAEEKVGVQKLVANTWNIFQPLLFGLVGTE
                     VSVESLESKTIGMCIATLCLALLVRILATFVLMSFANFRFMEKVFIALSWIPKATVQA
                     VLGPLALETARVMAPHLEGYSRNVMTVAFLAILITAPNGALIIGILGPKVLDHSEETF
                     PLKVELSNFHN"
     exon            520..580
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            581..740
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            741..911
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1054
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1182
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1358
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1465
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1615
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1724
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1861
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..2254
                     /gene="Slc9b1"
                     /gene_synonym="Nhedc1; Nhedc2; RGD1305087"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccttctgc ttccggtaaa ttccagccca gtttctgtcc ttggctctcc tgccatccct
       61 gcgcgagacg acggttgctg ggtctctggg aggtccttgc ttatttagaa agaagagaga
      121 gagagagaga tttacatcaa gactgacaaa attaacccac tgggcagatg ctatttatac
      181 caatagtgaa ttcggagaga tgaaccttca cgtgcgcctg taattgcaga tgtgttccag
      241 gattggtttg tgatttccag aaggctctca ttccttcccc caacccgctc ccctcatcag
      301 gattcctctt ggcttatccc agcggacaag cacttaacac caatgcggct taaggattaa
      361 ggactgtaat tgctcacaca gcgtgacaga cactgcactc gggggttctg acgatgcttt
      421 atggtggcgc tattattggg ataactgtca taaaagcttg tcacctttag gttttaaagt
      481 tccctgctga agactgcaaa ccaactcctg aaagatgagc gagtccaaca tagaagtaga
      541 caagaaggat gatcatctcc aatcatctat aactgatcag gctcctgaag aaccagaacc
      601 gaaggtacca caaatgaaag aatcaaaaat gaaggaaaca caaacgacca aaatagaaac
      661 agaggaatgg gaaagagaac acagcagtac aagtagtttc tgtcctccac agggaacagt
      721 aaataaaaca attaccgatg gagttacact cattgtatta tggattctac tctgggccct
      781 tataggtcaa gaagttctcc ctggtggaaa tttgtttggg cttgtagtta ttttttacag
      841 tgcttttctt gggggcaaaa ttatagaagt cattagaatt cctgtagtac ctcccctccc
      901 acctcttctt gggatgttac tggctggttt caccatcagg aacgttccga ttctttacaa
      961 atttgtccat attcctacct catggtcttc agctttaaga aacactgccc ttactattat
     1021 cctaatacga gctgggcttg gactggaccc acaggctttg aagcatctga agggagtttg
     1081 tctgagattg tccttcggtc catgcctcct agaggcgtgt tcagctgctc ttttctccca
     1141 cttcattatg aactttcctt ggcaatgggg gttcctatta ggttttgttc taggtgctgt
     1201 ctctcctgct gttgtcgttc ccaacatgct gctgttgcaa gagaacggat atggtgttga
     1261 gaagggcatt ccaaccttac tagtggctgc tagcagtatg gatgacatcg tggccatcac
     1321 tggattcaac acattcttga gcatagtctt ttcttcgggt agtgtaatta gcaatatcct
     1381 atcatctttg cgggatgttc ttattggcgt gctggtagga gttgttatgg gaatttttgt
     1441 tcagtatttt ccaagtagag atcaggagag acttacacag aggcgagcct tcctagttct
     1501 gagtatgtgt gtttctgctg tcttaggctg tcagcacatt ggcttacacg gatctggagg
     1561 actggtgaca ctagtgctgt ccttcatggc agcaaaacga tgggctgaag agaaggttgg
     1621 agtccaaaaa cttgttgcaa acacatggaa tatttttcag ccgcttcttt ttggcttagt
     1681 tggaacagaa gtgtctgttg aatctcttga atcgaaaact attggcatgt gcattgctac
     1741 cctgtgtttg gcactgcttg ttcgaatctt agccactttc gtgctgatgt cttttgctaa
     1801 ctttcgtttt atggagaaag tatttattgc tttatcatgg atccctaaag ctacagtcca
     1861 ggctgtcttg ggccctctag ctctagaaac agcaagggtc atggcacccc acttggaagg
     1921 atattcaagg aatgtgatga cagtggcctt tctagcaatc ctgattacag ctccaaatgg
     1981 agccctcatc attggcatac tgggacccaa agtacttgat catagtgagg agacattccc
     2041 tttaaaagtg gagctttcaa actttcataa ttaaaagttt gctattacca cctgctttgt
     2101 ctaatgaatt atctcacatg acgggaaaaa aaaaaaccat cacagtacaa aagtttaaag
     2161 actgttcata aaacccagga ttcactaaat gcacaatttc tctgcaaggc tttcctccgg
     2221 ttcaaagtga atttaataaa aatagttaac taca
//
