LOCUS       NM_001271438            3476 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 9 member A9 (Slc9a9), mRNA.
ACCESSION   NM_001271438 XM_001064905
VERSION     NM_001271438.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3476)
  AUTHORS   Zhang-James,Y., Middleton,F.A., Sagvolden,T. and Faraone,S.V.
  TITLE     Differential expression of SLC9A9 and interacting molecules in the
            hippocampus of rat models for attention deficit/hyperactivity
            disorder
  JOURNAL   Dev Neurosci 34 (2-3), 218-227 (2012)
   PUBMED   22777493
  REMARK    GeneRIF: abnormalities in SLC9A9-mediated signaling pathways could
            contribute to the ADHD phenotype of two rat models
REFERENCE   2  (bases 1 to 3476)
  AUTHORS   Zhang-James,Y., DasBanerjee,T., Sagvolden,T., Middleton,F.A. and
            Faraone,S.V.
  TITLE     SLC9A9 mutations, gene expression, and protein-protein interactions
            in rat models of attention-deficit/hyperactivity disorder
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 156B (7), 835-843 (2011)
   PUBMED   21858920
  REMARK    GeneRIF: The SLC9A9 gene sequence and expression profile in
            prefrontal cortex, dorsal striatum and hippocampus in two genetic
            rat models of attention deficit hyperactivity disorder, were
            examined.
REFERENCE   3  (bases 1 to 3476)
  AUTHORS   Nakamura,N., Tanaka,S., Teko,Y., Mitsui,K. and Kanazawa,H.
  TITLE     Four Na+/H+ exchanger isoforms are distributed to Golgi and
            post-Golgi compartments and are involved in organelle pH regulation
  JOURNAL   J Biol Chem 280 (2), 1561-1572 (2005)
   PUBMED   15522866
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Feb 11, 2021 this sequence version replaced NM_001271438.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.34034.1,
                                           SRR26643292.34978.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-339               JAXUCZ010000008.1  104112535-104112873
            340-542             JAXUCZ010000008.1  104127393-104127595
            543-620             JAXUCZ010000008.1  104157657-104157734
            621-697             JAXUCZ010000008.1  104159221-104159297
            698-813             JAXUCZ010000008.1  104246417-104246532
            814-919             JAXUCZ010000008.1  104294053-104294158
            920-1058            JAXUCZ010000008.1  104368757-104368895
            1059-1164           JAXUCZ010000008.1  104371668-104371773
            1165-1253           JAXUCZ010000008.1  104392376-104392464
            1254-1367           JAXUCZ010000008.1  104447805-104447918
            1368-1479           JAXUCZ010000008.1  104449270-104449381
            1480-1633           JAXUCZ010000008.1  104481208-104481361
            1634-1685           JAXUCZ010000008.1  104563852-104563903
            1686-1765           JAXUCZ010000008.1  104578115-104578194
            1766-1871           JAXUCZ010000008.1  104672735-104672840
            1872-3476           JAXUCZ010000008.1  104674340-104675944
FEATURES             Location/Qualifiers
     source          1..3476
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..3476
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /note="solute carrier family 9 member A9"
                     /db_xref="GeneID:363115"
                     /db_xref="RGD:1560736"
     exon            1..339
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..2099
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /note="solute carrier family 9 (sodium/hydrogen
                     exchanger); solute carrier family 9, subfamily A (NHE9,
                     cation proton antiporter 9), member 9; Na(+)/H(+)
                     exchanger 9; solute carrier family 9 member 9"
                     /codon_start=1
                     /product="sodium/hydrogen exchanger 9"
                     /protein_id="NP_001258367.1"
                     /db_xref="GeneID:363115"
                     /db_xref="RGD:1560736"
                     /translation="MAGQLRLTSGKDEDHFQHQGAVELLAFNFLLILTILTIWLFKNH
                     RFRFLHETGGAMVYGLIMGLILRYATAPTDIDSGTVYNCGKLLFSPSTLLVNITDQVY
                     EYKYQREINQHNISPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLG
                     SILTYAFLGTAISCVVIGLIMYGFVKAMVHAGQLKSGDFHFTDCLFFGSLMSATDPVT
                     VLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDTAAFFQSVG
                     NFLGIFAGSFAMGSAYAVVTALLTKFTKLREFPMLETGLFFLLSWSAFLSAEAAGLTG
                     IVAVLFCGVTQAHYTYNNLSSDSKLRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIF
                     NALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAI
                     RNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDESLKEEPSSQQE
                     ANKVDKDMTKTESAQLFRMWYGFDHKYLKPILTHSGPPLTTTLPAWCGPVSRLLTSPQ
                     AYGEQLKEDDVECIVNQDELAMNYQEQSPTSSSPATKLALDQKSSGLTLGKENIYEGD
                     LGLGGYELKLEQTRGQPQMD"
     exon            340..542
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            543..620
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            621..697
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            698..813
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            814..919
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1058
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1164
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1253
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1367
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1479
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1633
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1685
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1765
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..1871
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..3476
                     /gene="Slc9a9"
                     /gene_synonym="NHE-9; RGD1560736"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaagcccgt ctgaatgcta agccatctga atgcttgtga agtagcaaca aagtagcagc
       61 gtttattctg aaattctgtg ggcgccagtc tgtcctaggc aaccctcatc gaagtgctca
      121 tcccttgccc agggatttct ctgagcatca cggtggaggg gagaatggcg gggcagcttc
      181 ggcttacgtc agggaaggat gaagatcatt ttcaacacca gggagcagtg gagctactcg
      241 cgtttaattt tttgctcatc cttaccattt taacaatctg gttatttaaa aatcatcgat
      301 tccgcttctt gcatgagact ggaggggcga tggtgtatgg cctcataatg ggattaattt
      361 tgcgatatgc cacagcgcca actgatatcg atagtggcac tgtctacaat tgtggaaagt
      421 tactcttcag cccatcaact ctactagtca acatcactga ccaagtttat gaatacaagt
      481 accagagaga aatcaaccag cacaacatca gcccccacca aggcaatgct atactggaga
      541 agatgacgtt tgacccggaa atcttcttca atgtcttact acctcccatt atatttcatg
      601 caggatacag tctgaagaag agacactttt ttcaaaactt gggatccatt ttaacgtatg
      661 ccttcttggg aacagccatc tcctgtgtgg tcatagggtt aattatgtat ggctttgtga
      721 aggccatggt gcacgctggc cagctgaaga gcggagactt ccacttcact gactgtttgt
      781 tttttggttc actgatgtct gctacagatc cagtgacagt gctggccatt ttccatgagc
      841 tacacgtgga ccctgacctg tacacactgc tgtttgggga gagcgtgctg aatgatgcgg
      901 tggccatagt cctcacatac tctatatcca tctatagtcc caaggagaat cccaacgcgt
      961 ttgacacggc agcgttcttc caatctgtgg gcaatttcct ggggatcttt gccggctcct
     1021 ttgcgatggg ctctgcatac gcagttgtca cagcactgtt gaccaaattt accaagctcc
     1081 gtgagttccc aatgctggag acaggcctgt ttttcctgct ttcttggagt gccttcctgt
     1141 ctgccgaggc cgccggctta acaggcatag ttgcggttct cttctgtgga gtcactcaag
     1201 cacattacac ctacaacaat ctgtcatcgg attccaaact gaggaccaaa cagctgtttg
     1261 aatttatgaa cttcctggct gagaacgtca tcttctgcta catgggcctg gctctgttca
     1321 cctttcagaa tcacattttc aatgctcttt ttatactcgg agcctttcta gcaatttttg
     1381 tcgccagggc ctgcaacatt taccccctct ccttcctcct gaatctgggc agaaagcaga
     1441 agattccctg gaacttccag cacatgatga tgttttcagg tttgcgaggt gcaattgcct
     1501 tcgccctggc catccgcaac acggaatctc agcctaaaca gatgatgttc accaccacac
     1561 tgctcctcgt gttcttcact gtctgggtgt tcggaggagg aacgaccccc atgctgacat
     1621 ggcttcagat cagagtcggt gtggacctgg atgaaagttt gaaggaagag ccctcctcac
     1681 agcaggaagc aaataaggtg gataaagaca tgacgaagac agagagtgca cagctcttca
     1741 ggatgtggta cggatttgac cacaaatacc tgaaacccat cttaacacat tccggccctc
     1801 cactgaccac cacgttgccg gcatggtgtg gcccagtctc caggctgctc accagtcctc
     1861 aggcctatgg ggaacaactg aaagaggatg atgtggaatg tatcgtcaac caagatgaac
     1921 tcgccatgaa ttaccaggag cagagcccca cttccagcag tcctgccaca aagctagctc
     1981 tggaccagaa gtcttcaggc ctgactttag ggaaggaaaa catctacgag ggagacctcg
     2041 gcctcggagg ctatgaactc aaactggagc agactcgggg tcaaccccag atggactaat
     2101 tggtacaagt gcaaacataa ccacatgtaa tgcaagacca ctgaggaatg cccacagcca
     2161 aggaggtggt gcagaaagag acagaaagag tattaagaac ataaattgga cagaatcaaa
     2221 ccttatcaca tgtatcctcc cgtgccttca gaaatgagaa ttcattatct tccctctgta
     2281 ttatgcaacc tcatttaatt atctgacagc catttttact gctggattgg gggccagggg
     2341 agtcaggtct agctgccatt gggatgaacc atatgtgctg tgtctgcagg gggctccttc
     2401 tgttcctcag acagctctcc aggcccttca tgtggatttt ggattctatt ccattaatta
     2461 tagaacagta ataacatgaa gaagaagaaa aaaaatctcc tgagcataaa tgatgtctta
     2521 tcccttgact tgactccact tgtaccaacc atagggctaa atgcagagcc cagtgagtgt
     2581 tcagtaccca ctactgatgg cctcagagaa ttcacatctg tcgggggccc tgttgtcctt
     2641 gctggcactc tctccatacg gttcttccca ctactccaag gaggtgcttg cctccaggta
     2701 tgtgtatgtt aagtgcaggc tcttgccagc ttaaggagac tcattccagg gaaagctggt
     2761 ctctttccca cattctgtgt tttactcaaa cagtgagcct ctcttccttg tgtgcactgg
     2821 gacaacagtg cacaggttcc ctctgcatgc tgggaagtca tgcatgaccc tcccacatgg
     2881 ggggttgggg gggttgtgca ggagccctca cctttccaat tccaatatgt gtgactgttc
     2941 tgcaacagag gggcaaaaag aatggggcta atgacatgta ggccaccctt aggcaccaag
     3001 gacaagcacc agtcaggatc cacgcccctt tccagagtgg ctcacctgct gcattgaaga
     3061 gaccaaccca atagctttta atttagctgc atgacttgtg cctttgaagc cataagatac
     3121 ctcaagccta gcttctcctg aaatgcagat gctctgttag gctccaaaga gcaggcttca
     3181 gacttgggag cccaagacat gatagacttg ctttagaggg agatggagaa tgatttcttt
     3241 ctcaggccca aagcctaaaa ctaatgcatg ctgcactgag cacttcttag gccttagacc
     3301 tgtggtatca ggtaccctgc ctgtgtgtct gttttctcgc ttccaaatag tagaaactgg
     3361 gagaaacttt tatattcaac tgagtaaaat cttgtcattt caggtaaata gggcaagtag
     3421 aaaagttttc ttatttgaca tcatgctaat aaaattttgt tatggagtat gattgc
//
