LOCUS       NM_017217               2152 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus solute carrier family 7 member 3 (Slc7a3), mRNA.
ACCESSION   NM_017217
VERSION     NM_017217.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2152)
  AUTHORS   Huang,Y., Kang,B.N., Tian,J., Liu,Y., Luo,H.R., Hester,L. and
            Snyder,S.H.
  TITLE     The cationic amino acid transporters CAT1 and CAT3 mediate NMDA
            receptor activation-dependent changes in elaboration of neuronal
            processes via the mammalian target of rapamycin mTOR pathway
  JOURNAL   J Neurosci 27 (3), 449-458 (2007)
   PUBMED   17234578
  REMARK    GeneRIF: The influence of NMDA receptor activation on mammalian
            target of rapamycin (mTOR) activity and neuronal process extension
            is mediated by CAT3.
REFERENCE   2  (bases 1 to 2152)
  AUTHORS   Ito,K. and Groudine,M.
  TITLE     A new member of the cationic amino acid transporter family is
            preferentially expressed in adult mouse brain
  JOURNAL   J Biol Chem 272 (42), 26780-26786 (1997)
   PUBMED   9334265
REFERENCE   3  (bases 1 to 2152)
  AUTHORS   Hosokawa,H., Sawamura,T., Kobayashi,S., Ninomiya,H., Miwa,S. and
            Masaki,T.
  TITLE     Cloning and characterization of a brain-specific cationic amino
            acid transporter
  JOURNAL   J Biol Chem 272 (13), 8717-8722 (1997)
   PUBMED   9079705
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB000113.1.
            
            [WARNING] On Jul 18, 2024 this sequence was replaced by
            NM_017217.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB000113.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132271,
                                           SAMD00132278 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2152
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..2152
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /note="solute carrier family 7 member 3"
                     /db_xref="GeneID:29485"
                     /db_xref="RGD:68342"
     exon            1..389
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..1879
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /note="amino acid transporter, cationic 3; cationic amino
                     acid transporter y+; solute carrier family 7 (cationic
                     amino acid transporter, y+ system), member 3"
                     /codon_start=1
                     /product="cationic amino acid transporter 3"
                     /protein_id="NP_058913.1"
                     /db_xref="GeneID:29485"
                     /db_xref="RGD:68342"
                     /translation="MLWQALRRFGQKLVRRRLLELGMGETRLARCLSTLDLVALGVGS
                     TLGAGVYVLAGEVAKEKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSY
                     VTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILLNMPHVL
                     AEYPDFFALALVLLLTGLLVLGANESGLVTKVFTGMNLLVLGFVIISGFIKGELRNWK
                     LTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEE
                     AQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESPLPEAFTYVGWEPAR
                     YLVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHNGTHTPIVATVVSGV
                     IAAFMAFLFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQEMKNGEEEVELQEERT
                     LEAEKLTVQALFCQVDSIPTLLSGRIVYVCSSLLAVLLTVLCLVLTWWTTPLHSGDPV
                     WVTVVVLILGLILGISGVIWRQPQNRTPLHFKVPVVPLLPLVSIFVNVYLMMQMTADT
                     WARFGVWMLIGFAIYFGYGIQHSVEEVKNHQTLPKTRPQTIDLDLTTSCVHSI"
     exon            390..548
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            549..726
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            727..839
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            840..1062
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1202
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1305
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1472
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1639
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1748
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..2125
                     /gene="Slc7a3"
                     /gene_synonym="Atrc3; cat-3; Cat3; Slc7a2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcttcaatt ccaactagaa tgctgtggca ggcacttcga agatttggtc aaaagctggt
       61 gcggagacgt ttgctggagc tgggcatggg tgaaacccgc cttgccagat gcctgagcac
      121 tctcgactta gtggccctgg gtgtgggcag cacattaggt gcaggtgtgt atgtcctggc
      181 tggtgaggtg gccaaagaga aagcaggacc atccattgtg atctgctttt tggtggctgc
      241 tctgtcctct gtgttggctg gactgtgtta tgctgagttt ggtgcccggg tccccggctc
      301 tggttctgca tacctctaca gttatgtcac cgtaggtgaa ctctgggcct tcaccaccgg
      361 ctggaatctc attctctcct acgtcattgg tacagccagt gtggcccggg cttggagctc
      421 tgcttttgac aacctgattg gaaaccacat ctctcagact ctgaagggga ccatcttact
      481 gaacatgcct catgttcttg cagaatatcc agatttcttt gccttggccc ttgtgttgct
      541 gctcactgga ttgctggttt tgggggctaa tgaatccggc ctggttacca aagtgttcac
      601 agggatgaac cttttggttc tcgggtttgt catcatctct ggcttcatta agggagagct
      661 gagaaactgg aagctcacga aagaggacta ttgcttgact atgagtgaat ccaatggcac
      721 ttgtagcttg gattctatgg gctctggagg tttcatgcct tttggcttgg aagggattct
      781 ccgtggcgct gctacctgtt tctatgcctt cgttggtttt gactgtattg cgaccactgg
      841 ggaagaggct cagaatcccc agcgctccat ccctatgggt attgtgatct cactgtccat
      901 ctgctttttg gcttattttg gtgtgtcatc agcactgacg ctcatgatgc cttactacaa
      961 gcttcagcct gagagccctc tgcctgaagc ttttacctat gttggctggg agcctgcccg
     1021 ctacctggtg gctattggct ccctctgtgc actttctact agccttttgg gctctatgtt
     1081 tcctatgcct cgggtgatct atgcgatggc agaagatggc cttctgttcc gtgtccttgc
     1141 tagggtccac aatggcacac atacacccat tgtggccact gtggtatctg gtgttattgc
     1201 agcattcatg gcattcctct ttgaactcac tgatctcgtg gacctcatgt caatcgggac
     1261 tctgctcgct tactccctgg tgtcaatttg tgttcttatc ctcagatatc agcctgacca
     1321 agaaatgaag aacggtgaag aggaagtgga attgcaagag gagaggacac tcgaagcaga
     1381 aaagctgact gtccaggctc tattttgcca agtcgactcc atccccacac tcctttctgg
     1441 ccgaattgtc tatgtttgct catcactgct tgctgtacta ctaactgttc tttgcctggt
     1501 gctgacctgg tggacaactc cgcttcattc tggagaccca gtgtgggtca cagtggttgt
     1561 gctgatcctg gggctgatcc ttggaatttc tggggtcatc tggagacaac cacagaaccg
     1621 cactcccctt cattttaagg tgcccgttgt tcctctactc ccactggtga gcatctttgt
     1681 gaatgtttac ctgatgatgc aaatgacagc tgacacttgg gcccgatttg gggtctggat
     1741 gctgattgga tttgctatct acttcggcta tgggatccaa cacagcgtgg aagaagttaa
     1801 gaatcatcaa actctaccca agacaaggcc ccaaactata gaccttgatc tcaccacttc
     1861 ttgtgttcat agtatttgat gtaactatac ccaagtgttg tcttgttctc ctacacaata
     1921 atggagagta ctcttgaccc cacgaagagc tgggcctctc atgtgatgtt agtgatggat
     1981 atgaagtaga gctctgtatt tcttgcgaaa tgatggctaa ttctttgctg ttactttgtt
     2041 tttaacttgt ccactttgaa atagtctctg tagttgtttc ctggctttga aaaatgttat
     2101 taaaagaaaa ttgggaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
