LOCUS       NM_001399261             662 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SLC51 subunit beta (Slc51b), mRNA.
ACCESSION   NM_001399261
VERSION     NM_001399261.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Christian,W.V., Li,N., Hinkle,P.M. and Ballatori,N.
  TITLE     beta-Subunit of the Ostalpha-Ostbeta organic solute transporter is
            required not only for heterodimerization and trafficking but also
            for function
  JOURNAL   J Biol Chem 287 (25), 21233-21243 (2012)
   PUBMED   22535958
REFERENCE   2  (bases 1 to 662)
  AUTHORS   Li,N., Cui,Z., Fang,F., Lee,J.Y. and Ballatori,N.
  TITLE     Heterodimerization, trafficking and membrane topology of the two
            proteins, Ost alpha and Ost beta, that constitute the organic
            solute and steroid transporter
  JOURNAL   Biochem J 407 (3), 363-372 (2007)
   PUBMED   17650074
REFERENCE   3  (bases 1 to 662)
  AUTHORS   Ballatori,N., Christian,W.V., Lee,J.Y., Dawson,P.A., Soroka,C.J.,
            Boyer,J.L., Madejczyk,M.S. and Li,N.
  TITLE     OSTalpha-OSTbeta: a major basolateral bile acid and steroid
            transporter in human intestinal, renal, and biliary epithelia
  JOURNAL   Hepatology 42 (6), 1270-1279 (2005)
   PUBMED   16317684
REFERENCE   4  (bases 1 to 662)
  AUTHORS   Seward,D.J., Koh,A.S., Boyer,J.L. and Ballatori,N.
  TITLE     Functional complementation between a novel mammalian polygenic
            transport complex and an evolutionarily ancient organic solute
            transporter, OSTalpha-OSTbeta
  JOURNAL   J Biol Chem 278 (30), 27473-27482 (2003)
   PUBMED   12719432
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CN542934.1, BQ196694.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760389,
                                           SAMEA5760434 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               JAXUCZ010000008.1  74835010-74835109   c
            101-221             JAXUCZ010000008.1  74829747-74829867   c
            222-312             JAXUCZ010000008.1  74828316-74828406   c
            313-662             JAXUCZ010000008.1  74827047-74827396   c
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..662
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /note="SLC51 subunit beta"
                     /db_xref="GeneID:300790"
                     /db_xref="RGD:1565748"
     exon            1..100
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /inference="alignment:Splign:2.1.0"
     exon            101..221
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..514
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /note="organic solute transporter beta; solute carrier
                     family 51, beta subunit; solute carrier family 51 subunit
                     beta; solute carrier family 51 member beta"
                     /codon_start=1
                     /product="organic solute transporter subunit beta"
                     /protein_id="NP_001386190.1"
                     /db_xref="GeneID:300790"
                     /db_xref="RGD:1565748"
                     /translation="MDHSAEGAAASAEVPQELLEEMLWYFRSEDATPWNYSILVLAVL
                     VMVIGVVLLRRSILANRNRKKQPQDNGMPEDLHLDDSMKENSSLGILRETLISEKADL
                     APGETELNKRETSVVFLPDPQETES"
     exon            222..312
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /inference="alignment:Splign:2.1.0"
     exon            313..662
                     /gene="Slc51b"
                     /gene_synonym="Ostb; Ostbeta; RGD1565748"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgtgcattc ctgaggagag ttcctgtgag gaagaagagg aaaacacaga aaccagggcc
       61 gctctaccca gcctgaggtc ccaggaatcc cagatccagg cccagagacg tcttaaccag
      121 gatcaggagc atggaccaca gtgcagaagg agctgcagcc agtgccgagg tgccccagga
      181 gctgctggag gaaatgcttt ggtatttccg ttcagaggat gcaactcctt ggaactattc
      241 catcctggtt ctggcagtcc tggtgatggt gataggcgtg gtcctcctga gaaggagcat
      301 cctggcaaac agaaatcgaa agaagcagcc acaagacaac ggaatgccag aagacctgca
      361 tctagatgat tccatgaaag aaaacagcag cctgggcatc ctaagagaga cgctgatctc
      421 agagaaggca gacttggccc caggggaaac cgagttgaac aagagagaga catcagtcgt
      481 ctttctacca gacccccagg aaactgagag ctagggagtg tggagagacc acactgcccc
      541 agccagtcac acgactgtga tctgagccca gctctgaggc ctccaacccc ttaggttaga
      601 caaagcccca ccaagccacc taacttattt ttagcagacc caataaacac actacaatca
      661 ga
//
