LOCUS       NM_001107087            1603 bp    mRNA    linear   ROD 07-OCT-2023
DEFINITION  Rattus norvegicus solute carrier family 51 member A (Slc51a), mRNA.
ACCESSION   NM_001107087 XM_001072940 XM_221376
VERSION     NM_001107087.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1603)
  AUTHORS   Christian WV, Li N, Hinkle PM and Ballatori N.
  TITLE     beta-Subunit of the Ostalpha-Ostbeta organic solute transporter is
            required not only for heterodimerization and trafficking but also
            for function
  JOURNAL   J Biol Chem 287 (25), 21233-21243 (2012)
   PUBMED   22535958
REFERENCE   2  (bases 1 to 1603)
  AUTHORS   Li N, Cui Z, Fang F, Lee JY and Ballatori N.
  TITLE     Heterodimerization, trafficking and membrane topology of the two
            proteins, Ost alpha and Ost beta, that constitute the organic
            solute and steroid transporter
  JOURNAL   Biochem J 407 (3), 363-372 (2007)
   PUBMED   17650074
REFERENCE   3  (bases 1 to 1603)
  AUTHORS   Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL,
            Madejczyk MS and Li N.
  TITLE     OSTalpha-OSTbeta: a major basolateral bile acid and steroid
            transporter in human intestinal, renal, and biliary epithelia
  JOURNAL   Hepatology 42 (6), 1270-1279 (2005)
   PUBMED   16317684
REFERENCE   4  (bases 1 to 1603)
  AUTHORS   Seward DJ, Koh AS, Boyer JL and Ballatori N.
  TITLE     Functional complementation between a novel mammalian polygenic
            transport complex and an evolutionarily ancient organic solute
            transporter, OSTalpha-OSTbeta
  JOURNAL   J Biol Chem 278 (30), 27473-27482 (2003)
   PUBMED   12719432
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_221376.4, XM_001072940.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351,
                              SAMN11044071 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1603
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..1603
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /note="solute carrier family 51 member A"
                     /db_xref="GeneID:303879"
                     /db_xref="RGD:1311100"
     exon            1..390
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1375
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /note="solute carrier family 51, alpha subunit; organic
                     solute transporter alpha; solute carrier family 51 subunit
                     alpha"
                     /codon_start=1
                     /product="organic solute transporter subunit alpha"
                     /protein_id="NP_001100557.1"
                     /db_xref="GeneID:303879"
                     /db_xref="RGD:1311100"
                     /translation="MEPGRTHIKLDPRYTADLLELLETNYSISPACFSHPPTAAQLLR
                     ELGSVEIALTIILTFFTIGSVAIFLEDAIYLYKNTLCPIKKRTLIWSSSAPTVVSVFC
                     CFGLWIPRALTLVEMAITSFYAVCFYLLMMVMVEGFGGKEAVLRTLKDTPMRVHTGPC
                     CCCCPCCPPLILTRKKLQLLMLGPFQYAFFKIVMSIVGLFLIPDGIYDPAEISEKSAA
                     LWISNFLAVSTLLALWSLAILFRQAKLHLGEQNMGSKFALFQVLVILTALQPSIFSIL
                     ANSGQIACSPPYSSKIRSQVMNCHMLILETFLLTVLTRMYYRKKDNKVGYEACLPPDL
                     DSTLKA"
     exon            391..485
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            486..640
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            641..714
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            715..873
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            874..985
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1132
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1238
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1603
                     /gene="Slc51a"
                     /gene_synonym="Osta; Ostalpha; RGD1311100"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 taagggagtg tgaagtcgga agggttgggt agattgagaa caaggttgcg atcaaaggca
       61 tttgtctgaa agaggtggaa ggaaccacgc ctaagccatg gggaggagtt gggagatggc
      121 acagcagagg atcaaattcc tctgtggtga actctgagat aaaaagctga cactggaggc
      181 ttaaggaggt aaagaaaata gaagtggaag ctccacttac tgcttggccc tcacgcagtg
      241 gacaagaggc cctgagcacc tcagaaccgg gcagaaacct ccccactcct cagtggttgt
      301 ccctacctga ccctcctcat cctcggcagc atctgcctga gagaaaagaa ggatggagcc
      361 aggcaggact catataaaac ttgaccccag gtacacagca gatcttctgg agctgctgga
      421 aaccaattac agcatctccc ctgcctgctt ctctcaccct cccactgcag cccagctcct
      481 gagagaattg ggctcagtgg aaattgccct caccatcatc ttgacctttt ttaccattgg
      541 atcagttgcc atttttctgg aggatgctat ttacctatac aagaacaccc tttgccccat
      601 caagaagagg actctgatct ggagtagctc tgcgcccacg gtggtgtctg tgttctgctg
      661 ctttggtctc tggatcccac gtgccctcac acttgtggaa atggccataa cctcgtttta
      721 tgccgtatgc ttttacctgc tgatgatggt catggtggaa ggctttggtg ggaaggaagc
      781 agtactaagg acactgaagg acaccccaat gagggtgcac acaggtccct gctgctgctg
      841 ctgtccctgc tgcccacccc tcatacttac caggaagaag ctacagttgc tcatgttggg
      901 ccctttccag tatgccttct tcaagatagt gatgagcata gtgggcctgt ttctcattcc
      961 tgatggcatc tatgacccag cagaaatttc tgagaagagc gcagctctct ggatcagcaa
     1021 tttccttgct gtgtccaccc ttttggctct ctggtccctg gccatccttt tccgtcaagc
     1081 caagttgcac ctgggtgaac agaatatggg atccaagttt gctctgttcc aggtgcttgt
     1141 catcctgacc gccctgcagc cctccatttt ctccatcttg gctaacagcg ggcagatcgc
     1201 ttgctcacct ccctattctt ctaaaatcag gtcccaagtg atgaactgtc acatgctcat
     1261 cctggagacc ttcctgttga cagtgctgac acgcatgtac tatcgaaaga aagataacaa
     1321 ggttgggtat gaggcttgtt taccgccaga cctggactca acgctcaaag cctgacaaga
     1381 gcggcttgga ctatggaaga gtcactgcac tcctcggaag agcgtggatt tcctctgtcc
     1441 ctgagcctta tcagtggtta aggctcccac tgacagggca ggctggcagc cgtcatggga
     1501 ctataggaat gagggtaaag tgcagtagac ggaacctgtt ttgagtcttt ctcaggaaag
     1561 ttttgtaata aatggtgaaa gcagagatgc ttgcacaaaa tac
//
