LOCUS       NP_001099915             221 aa            linear   ROD 03-APR-2024
DEFINITION  sugar transporter SWEET1 precursor [Rattus norvegicus].
ACCESSION   NP_001099915 XP_001072473 XP_215626
VERSION     NP_001099915.1
DBSOURCE    REFSEQ: accession NM_001106445.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 221)
  AUTHORS   Chen,L.Q., Hou,B.H., Lalonde,S., Takanaga,H., Hartung,M.L.,
            Qu,X.Q., Guo,W.J., Kim,J.G., Underwood,W., Chaudhuri,B.,
            Chermak,D., Antony,G., White,F.F., Somerville,S.C., Mudgett,M.B.
            and Frommer,W.B.
  TITLE     Sugar transporters for intercellular exchange and nutrition of
            pathogens
  JOURNAL   Nature 468 (7323), 527-532 (2010)
   PUBMED   21107422
REFERENCE   2  (residues 1 to 221)
  AUTHORS   Barnhill,J.C., Stokes,A.J., Koblan-Huberson,M., Shimoda,L.M.,
            Muraguchi,A., Adra,C.N. and Turner,H.
  TITLE     RGA protein associates with a TRPV ion channel during biosynthesis
            and trafficking
  JOURNAL   J Cell Biochem 91 (4), 808-820 (2004)
   PUBMED   14991772
REFERENCE   3  (residues 1 to 221)
  AUTHORS   Tagoh,H., Kishi,H. and Muraguchi,A.
  TITLE     Molecular cloning and characterization of a novel stromal
            cell-derived cDNA encoding a protein that facilitates gene
            activation of recombination activating gene (RAG)-1 in human
            lymphoid progenitors
  JOURNAL   Biochem Biophys Res Commun 221 (3), 744-749 (1996)
   PUBMED   8630032
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473976.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001072473.1, XP_215626.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..221
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..221
                     /product="sugar transporter SWEET1 precursor"
                     /note="sugar transporter SWEET1; RAG1-activating protein
                     1; recombination activating gene 1 activating protein 1;
                     solute carrier family 50 (sugar transporter), member 1;
                     solute carrier family 50 (sugar efflux transporter),
                     member 1"
                     /calculated_mol_wt=21913
     sig_peptide     1..28
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2799
     Site            3..23
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Region          9..95
                     /region_name="MtN3_slv"
                     /note="Sugar efflux transporter for intercellular
                     exchange; pfam03083"
                     /db_xref="CDD:397278"
     Site            44..63
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Site            68..88
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Site            102..122
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Region          127..213
                     /region_name="MtN3_slv"
                     /note="Sugar efflux transporter for intercellular
                     exchange; pfam03083"
                     /db_xref="CDD:397278"
     Site            129..149
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Region          149..221
                     /region_name="Mediates interaction with TRPV2.
                     /evidence=ECO:0000269|PubMed:14991772"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Site            160..180
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     Site            186..206
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZH22.1)"
     CDS             1..221
                     /gene="Slc50a1"
                     /gene_synonym="Rag1ap1; RGD1308478"
                     /coded_by="NM_001106445.1:99..764"
                     /db_xref="GeneID:295245"
                     /db_xref="RGD:1308478"
ORIGIN      
        1 meaggvadsf lssacvlftl gmfstglsdl rhmqrtrsvd niqflpfltt dvnnlgwlsy
       61 gvlkgdgtli ivntvgavlq tlyilaylhy spqkhavllq tatllavlll gygyfwllvp
      121 dletrlqqlg lfcsvftism ylspladlak iiqtkstqrl sfsltiatll sstswsiygf
      181 rlkdpyitvp nlpgiltgfi rlvlfykypp eqdtkyrllq t
//
