LOCUS       NM_012651               4508 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 4 member 1 (Diego blood
            group) (Slc4a1), mRNA.
ACCESSION   NM_012651 XM_001081509
VERSION     NM_012651.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Xiong,Y., Li,Y., Xiong,Y., Zhao,Y., Tang,F. and Wang,X.
  TITLE     Cluster of erythrocyte band 3: a potential molecular target of
            exhaustive exercise-induced dysfunction of erythrocyte
            deformability
  JOURNAL   Can J Physiol Pharmacol 91 (12), 1127-1134 (2013)
   PUBMED   24289085
  REMARK    GeneRIF: in the structure and function of erythrocyte band 3.
REFERENCE   2  (bases 1 to 4508)
  AUTHORS   Shnitsar,V., Li,J., Li,X., Calmettes,C., Basu,A., Casey,J.R.,
            Moraes,T.F. and Reithmeier,R.A.F.
  TITLE     A substrate access tunnel in the cytosolic domain is not an
            essential feature of the solute carrier 4 (SLC4) family of
            bicarbonate transporters
  JOURNAL   J Biol Chem 288 (47), 33848-33860 (2013)
   PUBMED   24121512
REFERENCE   3  (bases 1 to 4508)
  AUTHORS   Al-Samir,S., Papadopoulos,S., Scheibe,R.J., Meissner,J.D.,
            Cartron,J.P., Sly,W.S., Alper,S.L., Gros,G. and Endeward,V.
  TITLE     Activity and distribution of intracellular carbonic anhydrase II
            and their effects on the transport activity of anion exchanger
            AE1/SLC4A1
  JOURNAL   J Physiol 591 (20), 4963-4982 (2013)
   PUBMED   23878365
REFERENCE   4  (bases 1 to 4508)
  AUTHORS   Villaescusa,R., Arce,A.A., Lalanne-Mistrih,M.L., Lamarre,Y.,
            Hierso,R., Hernandez,C. and Hardy-Dessources,M.D.
  CONSRTM   CAREST study group
  TITLE     Natural antiband 3 antibodies in patients with sickle cell disease
  JOURNAL   C R Biol 336 (3), 173-176 (2013)
   PUBMED   23643401
REFERENCE   5  (bases 1 to 4508)
  AUTHORS   Khositseth,S., Bruce,L.J., Walsh,S.B., Bawazir,W.M., Ogle,G.D.,
            Unwin,R.J., Thong,M.K., Sinha,R., Choo,K.E., Chartapisak,W.,
            Kingwatanakul,P., Sumboonnanonda,A., Vasuvattakul,S.,
            Yenchitsomanus,P. and Wrong,O.
  TITLE     Tropical distal renal tubular acidosis: clinical and
            epidemiological studies in 78 patients
  JOURNAL   QJM 105 (9), 861-877 (2012)
   PUBMED   22919024
  REMARK    Review article
REFERENCE   6  (bases 1 to 4508)
  AUTHORS   Li,J.Y., Li,J.X. and Yang,Z.M.
  TITLE     Abnormalities of ion-exchange proteins of the red cell membrane in
            iron deficiency anemia
  JOURNAL   Chin Med J (Engl) 105 (2), 116-119 (1992)
   PUBMED   1317772
REFERENCE   7  (bases 1 to 4508)
  AUTHORS   Jarolim,P., Palek,J., Amato,D., Hassan,K., Sapak,P., Nurse,G.T.,
            Rubin,H.L., Zhai,S., Sahr,K.E. and Liu,S.C.
  TITLE     Deletion in erythrocyte band 3 gene in malaria-resistant Southeast
            Asian ovalocytosis
  JOURNAL   Proc Natl Acad Sci U S A 88 (24), 11022-11026 (1991)
   PUBMED   1722314
REFERENCE   8  (bases 1 to 4508)
  AUTHORS   Kudrycki,K.E. and Shull,G.E.
  TITLE     Primary structure of the rat kidney band 3 anion exchange protein
            deduced from a cDNA
  JOURNAL   J Biol Chem 264 (14), 8185-8192 (1989)
   PUBMED   2722777
REFERENCE   9  (bases 1 to 4508)
  AUTHORS   Kay,M.M., Bosman,G.J., Shapiro,S.S., Bendich,A. and Bassel,P.S.
  TITLE     Oxidation as a possible mechanism of cellular aging: vitamin E
            deficiency causes premature aging and IgG binding to erythrocytes
  JOURNAL   Proc Natl Acad Sci U S A 83 (8), 2463-2467 (1986)
   PUBMED   3458208
REFERENCE   10 (bases 1 to 4508)
  AUTHORS   Bennett,V. and Stenbuck,P.J.
  TITLE     The membrane attachment protein for spectrin is associated with
            band 3 in human erythrocyte membranes
  JOURNAL   Nature 280 (5722), 468-473 (1979)
   PUBMED   379653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            L02943.1 and BC085748.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_012651.3.
            
            On or before Jun 25, 2006 this sequence version replaced
            XM_001081509.1, NM_012651.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132285, SAMD00132293
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-345               L02943.1           1-345
            346-4508            BC085748.1         357-4519
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..4508
                     /gene="Slc4a1"
                     /note="solute carrier family 4 member 1 (Diego blood
                     group)"
                     /db_xref="GeneID:24779"
                     /db_xref="RGD:3710"
     exon            1..141
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            142..224
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             210..2996
                     /gene="Slc4a1"
                     /note="AE 1; anion exchanger 1; anion exchange protein 1;
                     solute carrier family 4 (anion exchanger), member 1;
                     Solute carrier family 4, member 1, anion exchange protein
                     1 (kidney band 3)"
                     /codon_start=1
                     /product="band 3 anion transport protein"
                     /protein_id="NP_036783.2"
                     /db_xref="GeneID:24779"
                     /db_xref="RGD:3710"
                     /translation="MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQES
                     EALPTEQTATDYIPTSTSTSHPSSSQVYVELQELMMDQRNQELQWVEAAHWIGLEENL
                     REDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIR
                     PQDRDELLRALLLKRSHAEDLKDLEGVKPAVLTRSGAPSEPLLPHQPSLETKLYCAQA
                     EGGSEEPSPSGILKIPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLEDLVLPEPVS
                     FLLVLLGPEAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGELLSSLDSFLDCSLVL
                     PPTEAPSEKALLNLVPVQKELLRKRYLPRPAKPDPNLYEALADGGKEGPGDEDDPLRR
                     TGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTR
                     NLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFYSFCESNNLEYIVGR
                     AWIGFWLILLVVLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYP
                     LQESYAPVVMKPKPQGPVPNTALLSLVLMVGTFLLAMMLRKFKNSTYFPGKLRRVIGD
                     FGVPISILIMVLVDTFIKNTYTQKLSVPDGLKVSNSSARGWVIHPLGLYNHFPKWMMF
                     ASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPW
                     LSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILS
                     RIPLAVLFGIFLYMGITSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGI
                     QIICLAVLWVVKSTPASLALPFVLILTVPLRRLLLPLIFRELELQCLDGDDAKVTFDE
                     AEGLDEYDEVPMPV"
     exon            225..345
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            346..419
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            420..600
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            601..736
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..860
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            861..942
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1124
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1335
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1545
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1694
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1695..1889
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2060
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2150
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2317
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2318..2571
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..2741
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2742..2915
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..4482
                     /gene="Slc4a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagggcatga gtcaggggtt tgggagcctc ccccagggca cctgccggtg ctgttagagc
       61 agttgggagc tcggccagtc tcagagggca ccggcggcag caggcgggac ttcacaaagg
      121 acccccgaga ttcctgagca gggacctgag gtgcaggtta tgctgggggc tcagagagca
      181 gaggacaact ggacaccgag gacagcatca tgggggacat gcaggaccac gagaaagtgc
      241 tggagatccc agaccgtgac agtgaagagg aactggaaca tgtaatagaa cagatagcat
      301 acagagacct agacatccct gtgacagaaa tgcaggagtc agaagctctt cccacagagc
      361 aaacagccac agactacatc cccaccagta cctccacatc gcacccaagc tccagtcagg
      421 tctatgtaga gctgcaggaa ctgatgatgg accagaggaa ccaggaacta cagtgggtgg
      481 aggcggcaca ctggataggg ctggaggaaa accttcgaga ggatggtgtg tggggtcgtc
      541 cacatctctc ttacctcacc ttctggagcc ttctagaact gcagaaggtc ttctcaaaag
      601 gcaccttcct tctggatctg gcagagacat ccctggctgg ggtggccaat aaacttctag
      661 acagtttcat ctatgaggat caaattcggc ctcaagaccg agatgagctg ctccgggctc
      721 tgctactcaa acgcagccac gctgaggacc taaaggatct ggagggagtg aagcctgccg
      781 tcctgacccg ctctggggcc ccttctgaac ctcttcttcc tcaccagcca tcgctggaga
      841 ccaagctgta ctgtgcacag gcagaggggg gctcagaaga accctcgcca tctgggattc
      901 tgaagatccc ccccaattca gaaaccacat tggtgctagt gggccgggct agtttcctgg
      961 tgaagcctgt gctgggcttc gtgagactga aggaagctgt gccgctggag gacctggtgt
     1021 tgccggagcc tgtgagcttc cttctagttc ttctcggacc tgaggctccg cacatcgact
     1081 acacccagct gggcagggct gcagcaactc tcatgacaga aagagtgttc cgcgttaccg
     1141 cctccctggc gcagagccga ggggagctgc tgagctccct ggatagcttt ctggactgta
     1201 gcctggtgct gccgcccaca gaggcccctt cagagaaagc tctgctcaac ctggtgcccg
     1261 tgcagaagga gttgcttagg aagcggtact tgcccagacc tgccaagcca gaccccaact
     1321 tgtacgaggc attagcagac gggggaaagg agggccccgg tgacgaagac gaccctctaa
     1381 ggcgcaccgg ccggatcttt ggaggcctga tccgtgatat ccggcgccgg tatccttact
     1441 acctgagtga catcaccgat gcgctcagtc cccaggtgct ggctgctgtc atcttcatct
     1501 actttgctgc cttgtcacct gcggtcacct tcggcggtct cctgggagaa aagacccgga
     1561 acctgatggg ggtgtcagag ctgctcatct ccacagcagt gcaaggaatt ctctttgctc
     1621 tcctgggggc acagcccctg cttgtgctcg gcttctcagg acccctgctg gtgtttgaag
     1681 aagccttcta ctcgttctgt gaaagcaata acctggagta catcgtgggc cgcgcgtgga
     1741 tcggcttctg gcttatcctg ctggtggtgt tggtggtggc ctttgaaggc agcttcctgg
     1801 tccaatacat ctcccgctac actcaggaga tcttctcctt cctcatctcc ctcatcttca
     1861 tctatgagac tttctctaag ctgatcaaga ttttccagga ctacccgcta caagagagct
     1921 atgcccctgt tgtgatgaag cccaaacctc agggccccgt gcccaacaca gccctcctct
     1981 cccttgtgct tatggttggt accttcctac ttgccatgat gctacgaaag ttcaagaaca
     2041 gcacctactt ccccggcaag ctacgcagag tcattgggga ctttggggtc cccatctcca
     2101 tcctgataat ggtcctggtg gataccttca tcaagaacac ctacacgcag aaactctcgg
     2161 tgcctgatgg ccttaaagtg tccaactcct ccgcccgggg ctgggtcatc catcccctgg
     2221 gtctgtataa ccatttcccc aagtggatga tgtttgcttc tgttctaccc gctctgcttg
     2281 tcttcatcct tatattcctt gagtctcaga tcaccacgct gattgtcagt aaacctgagc
     2341 ggaagatgat caagggctcc ggcttccacc tggacttgct gctggttgtt ggcatgggcg
     2401 gggtggccgc cctctttggg atgccttggc tcagcgccac cactgtgcgt tctgttaccc
     2461 atgccaacgc cctcacagtc atggggaagg ccagtggtcc aggggctgca gcccagatcc
     2521 aagaggtcaa ggaacagcgg atcagtgggc tcctggtctc tgtgctcgtg ggactgtcca
     2581 ttctcatgga acccatcctg tcccgcatcc ccctggccgt actgtttggc atcttcctgt
     2641 acatggggat cacatccctc agtggcatcc agctctttga ccgcatcttg ctcctgttca
     2701 agccacccaa gtaccaccca gatgtgccct ttgtcaagag ggtgaagacc tggcgtatgc
     2761 acctcttcac gggcatccag atcatctgcc tggctgtgct gtgggtggtg aagtccacgc
     2821 cagcctcgct ggccctgccc tttgtcctca tcctcaccgt gcccctgcgt cgtctcctcc
     2881 tgccgctcat cttcagagag ctagaactcc agtgtctgga tggtgatgat gccaaagtga
     2941 cctttgacga ggcggaaggg ctggatgagt atgacgaagt gcccatgcct gtgtgagggg
     3001 caggcccagg cccccaacca ctccactttc ccaccctcct gggaagacca ttcatgggca
     3061 tgtcatggct gtgggtgggg aaggagaggt tgtctaggaa actctctaca taaggtatac
     3121 gggattttct ggctggagac gaccagaagt tatatcaggg aattggggtc acagtctctt
     3181 gcgactgtac gggtcccatg tggcatagtt ataaatagca aaggggagac acttttcaag
     3241 ttcctgctgg ctgtgtggcc ttaagtaagt cccttgacct ctctggcctc tgccccctac
     3301 tctatagaat gtatgcattg gtaataatac ccatgttacc ggctgctgag gaccaagagc
     3361 aaatgtctaa gaactattac agtcttcatt gttctcagag cctgcccaga tcacacagcc
     3421 ccctcccccc cacccggggc cacacagcag ggacctgagc ctcctgacct ggaggctaca
     3481 gctctgtcct ccgtcttccc agtcatgccc agaaataccc ctaatgtctt ccattttctg
     3541 tcccaccccc accccaagtc tcccttctct gcatctagag agatattctg atgagagtaa
     3601 gatacaggtg agggactgag gctcgtattc ctaagtactt gctctctctc accaggtgtt
     3661 cattcattca ttcattcatt cattcattca ttcatacatt ccatagccat ctactaaagg
     3721 ccctagacct agtggacaca gaggggctgg ttcaagcttc ttttgcgggg tgaggccaat
     3781 acataagtct gctctggaca tggatgggga tagcgggagg atgggagggt tgtaatttat
     3841 taactgtgta ttttctgagt gcttcttccg tgccttggtt ttgcccacac actcagccct
     3901 catgagagac ttgctgtgtc caaccccagc taaactgagt cttgggggag cgaaacccaa
     3961 gttttgaccc attggagtag gagacagtag cttgttcaaa atatggataa acaactattt
     4021 ttatttttga caaagcaata tatttttttt aaaaaaaaaa aaagttgaaa gaaccagaac
     4081 ttgagagaag aaacagaaga tctgagtgat caggcagcag ggggcttcca gtggaagatg
     4141 ctgggggggg ggatttgaga gcccatgttt gcctcccagg actgcctcac cacagactct
     4201 tgttccctca tcatagaaat agggacaagg atgcacctac cttgtaggga gttggaagga
     4261 ttgactgaca ccgtataaga aaagcatttg cagagcacac agccttcctt gtggggagtt
     4321 gctgatgtga ccacgccgct gggcacaccc ctatcctctc ctgcctttcc tactccttga
     4381 acattaccaa agagagtggg gatcctgctg cccactctcc agcgcccttc cccaccgccg
     4441 tgcttgggaa taggttttgc caataaatgt gtctgtgtta aaaaaaaaaa aaaaaaaaaa
     4501 aaaaaaaa
//
