LOCUS       NM_001106652            1985 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 46, member 2 (Slc46a2),
            mRNA.
ACCESSION   NM_001106652 XM_001062037 XM_232946
VERSION     NM_001106652.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Paik,D., Monahan,A., Caffrey,D.R., Elling,R., Goldman,W.E. and
            Silverman,N.
  TITLE     SLC46 Family Transporters Facilitate Cytosolic Innate Immune
            Recognition of Monomeric Peptidoglycans
  JOURNAL   J Immunol 199 (1), 263-270 (2017)
   PUBMED   28539433
REFERENCE   2  (bases 1 to 1985)
  AUTHORS   Ahn,S., Lee,G., Yang,S.J., Lee,D., Lee,S., Shin,H.S., Kim,M.C.,
            Lee,K.N., Palmer,D.C., Theoret,M.R., Jenkinson,E.J., Anderson,G.,
            Restifo,N.P. and Kim,M.G.
  TITLE     TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by
            direct presentation
  JOURNAL   PLoS Biol 6 (8), e191 (2008)
   PUBMED   18684012
REFERENCE   3  (bases 1 to 1985)
  AUTHORS   Kim,M.G., Flomerfelt,F.A., Lee,K.N., Chen,C. and Schwartz,R.H.
  TITLE     A putative 12 transmembrane domain cotransporter expressed in
            thymic cortical epithelial cells
  JOURNAL   J Immunol 164 (6), 3185-3192 (2000)
   PUBMED   10706709
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474039.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232946.4, XM_001062037.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN09345238,
                              SAMN09345329 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     gene            1..1985
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /note="solute carrier family 46, member 2"
                     /db_xref="GeneID:298034"
                     /db_xref="RGD:1310485"
     exon            1..1268
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..1576
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /note="thymic stromal cotransporter homolog"
                     /codon_start=1
                     /product="solute carrier family 46 member 2"
                     /protein_id="NP_001100122.1"
                     /db_xref="GeneID:298034"
                     /db_xref="RGD:1310485"
                     /translation="MGPGFTCPWSGSLSGFRVRTWIEPVVASTQVAGSLYDTGLLLVL
                     KESFASDARDSSNYSANQSLGERQEDQQQKAISNFYIIYNLVVGLTPLLSAYVLGWLS
                     DRYHRKISICTAMLGFLLSRIGLLLKVMLDWPLEVMYGAAALNGLCGGFSAYWSGVMA
                     LGSLSCSQSRRSVRLILIDLVLGLAGFCGSMASGHLFKQIVGHSAQGLLLTACSVGCA
                     AFALFYSLFVLKVPEAVSKPNKVHPTVDTVSGMMGTYRTLDPDQQDKPNIQANPPTPG
                     KEKPSQAIIALLFVGAIVYDLAVVGTLDVMALFVLKDPLHWNQVQLGYGMASGYIIFI
                     TSFLGVLVFSRYFRDTTMIIIGMVSFGSGALLLAFVKKTYMFYIARAVMLFALIPITT
                     IRSAMSKLVKDSSYGKIFVILQLCLALTGVVTSTMYNKIYQLTLNKFAGTCFLLSSFL
                     SFLAIVPIGVVAYKQVPGSRQGECADTQRS"
     exon            1269..1352
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1509
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1985
                     /gene="Slc46a2"
                     /gene_synonym="Tscot"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacacagcca cctcagctct gctctcgagg cacgcacttg aaacactctg ggactgagcc
       61 ctgaccctcc aaatttggga gcatctccca gactctgcag acagcaaggc ccgttccctg
      121 tcacacaggt cacatgggtc ccgggttcac ctgtccgtgg agcggctcgc tctctggctt
      181 ccgggtgagg acttggatcg agcctgtggt ggcttcaacc caggtggccg gttccctcta
      241 tgatacagga ctacttctgg tactgaagga gtcctttgca tctgacgcta gagactcctc
      301 taattacagt gccaaccagt cgctggggga acgtcaggag gaccaacagc agaaggccat
      361 ctccaatttc tacatcattt acaacctcgt ggtgggcctg acacccctgc tgtccgccta
      421 tgtactgggc tggctcagcg accgctacca ccgtaagatc tctatctgca cggcgatgct
      481 gggcttcctt ctgtcccgca tcggactctt actcaaagtg atgctggact ggccactgga
      541 ggtgatgtac ggagcagcgg cgctcaatgg gctgtgcggg ggcttctccg cttattggtc
      601 cggggtcatg gcgctgggat ccctgagctg ctcccaaagc cgccgctccg tgcgcctcat
      661 cctcatcgat ttagtcctag gcttggctgg gttctgtggc agtatggctt cagggcatct
      721 cttcaagcaa atcgttgggc actctgcgca aggccttctg ttaaccgcct gcagcgtggg
      781 ctgtgcggcg tttgcccttt tctacagtct cttcgtgcta aaggtccctg aagctgtgtc
      841 caagcccaac aaggtgcacc ccactgtaga tactgtgtct ggcatgatgg gcacctatcg
      901 aaccctggat ccagatcaac aggacaagcc taatatacag gcaaaccctc caactcctgg
      961 aaaagagaag ccttcccaag ccatcattgc tctgctgttt gtgggcgcca ttgtttatga
     1021 ccttgctgtc gtgggcacat tggacgttat ggcccttttc gtgctaaagg atcctctcca
     1081 ttggaaccaa gtgcagctgg gctatgggat ggcttctggg tacataatct tcataaccag
     1141 cttcttgggt gtcttggtct tctcccgcta cttccgggac accacgatga tcataattgg
     1201 gatggtttcc tttgggtctg gagcccttct cttggccttt gtgaagaaga catacatgtt
     1261 ctatattgcc cgagctgtca tgctgtttgc acttattccc atcacaacca tccggtcagc
     1321 catgtccaag cttgtaaagg actcttccta tggaaagatt ttcgtcatac tgcagctgtg
     1381 cctagctctg actggggtgg tgacatccac catgtacaac aagatctatc agcttacgct
     1441 gaacaagttc gccggcacct gctttcttct gtcttctttt ctctccttct tggccattgt
     1501 cccaattggt gttgtggcct acaaacaagt cccggggtca cgacaaggag agtgtgcgga
     1561 tacacagagg agctgaaatg ccagcgagaa caaggttctg cccgtgagac ccaagttcca
     1621 gtcttcccat aaccctcggg tccctagtgg gagggaaatc gccttctggg tgttgcagga
     1681 aatttcctag tgctcctcca atgcctctgc taggcagagg tcaggcctgg gtgtaccagc
     1741 tgctggctcg ggcattctgg gtcctggagg gcttcaggct ccagccagcc agccccttac
     1801 ttccattgct atcttaacga tgccagtgga ggaacatggg gatcgtgcta gttctatgga
     1861 agactgtgac taaagcctaa acttcaccag cccaagggga atgaacacga aacggacagt
     1921 ttgctaaaac tgacaacagt tttgcacaca tgacaacagt ttataaatta atataaaatc
     1981 ttggg
//
