LOCUS       NM_144747               2482 bp    mRNA    linear   ROD 12-DEC-2024
DEFINITION  Rattus norvegicus solute carrier family 45, member 1 (Slc45a1),
            mRNA.
ACCESSION   NM_144747
VERSION     NM_144747.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2482)
  AUTHORS   Srour,M., Shimokawa,N., Hamdan,F.F., Nassif,C., Poulin,C., Al
            Gazali,L., Rosenfeld,J.A., Koibuchi,N., Rouleau,G.A., Al Shamsi,A.
            and Michaud,J.L.
  TITLE     Dysfunction of the Cerebral Glucose Transporter SLC45A1 in
            Individuals with Intellectual Disability and Epilepsy
  JOURNAL   Am J Hum Genet 100 (5), 824-830 (2017)
   PUBMED   28434495
REFERENCE   2  (bases 1 to 2482)
  AUTHORS   Shimokawa,N., Okada,J., Haglund,K., Dikic,I., Koibuchi,N. and
            Miura,M.
  TITLE     Past-A, a novel proton-associated sugar transporter, regulates
            glucose homeostasis in the brain
  JOURNAL   J Neurosci 22 (21), 9160-9165 (2002)
   PUBMED   12417639
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC093599.1.
            
            On Sep 13, 2012 this sequence version replaced NM_144747.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC093599.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2482              BC093599.1         1-2482
FEATURES             Location/Qualifiers
     source          1..2482
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2482
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /note="solute carrier family 45, member 1"
                     /db_xref="GeneID:246258"
                     /db_xref="RGD:708502"
     exon            1..67
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            68..488
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..2347
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /codon_start=1
                     /product="proton-associated sugar transporter A"
                     /protein_id="NP_653348.3"
                     /db_xref="GeneID:246258"
                     /db_xref="RGD:708502"
                     /translation="MMIPPAGSTPPGEALIPSVAPQDFWRSPISSYSGSVTRHISHRA
                     NNFKRHPKRRKYIRPSPPPPPNTPCPIELVDFEDLHPQRSFWELLFNGCILFGIEFSY
                     AMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFIL
                     VLAIGALLGLSLLLNGRDIGMALADTATNHKWGILLTVCGVVLMDFSADSADNPSHAY
                     MMDVCGPVDQDRGLNIHALMAGLGGGFGYVVGGIHWDKTSFGRALGGQLRVIYIFTAI
                     TLSVTTVLTLVSIPERPLRPLGEKRTAMKSPSLPLPPSPPVLLEEGAGDTLPSTTATS
                     LYASFSSPISPPSPLTPKYGSFISRDSSLTGINEFASSFGTSNIDSVLIDCFTAGHDN
                     YLALPSSVPRQAISVSFPRAPDGFYCQERGLERREGPLTLGLDGDVLRVGSLDTSKPR
                     ASGILKRPQTLALPDVAGGNGPETSRRRNVTFSQQVANILLNGVKYESELTGSSEQSE
                     QPLSLRRLCSTIYNMPRALRNLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHA
                     SEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEECLSVRTLYFIAYLSFGLGTGL
                     ATLSRNLYVVLSLCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDIS
                     LLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFASLVSFLGCLYSSLCVTYEIPSADA
                     ADEERQPLLLNV"
     exon            489..581
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            582..806
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            807..1543
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1697
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1874
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2080
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2482
                     /gene="Slc45a1"
                     /gene_synonym="Dnb5; Past-A; Pasta"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagctgta cccgggagaa ccaggagccc agcctgggaa agggatgcct cccgtctgga
       61 cgcacagcga cgcccaccag ccctgcctat gatgatcccc ccagcaggca gcacccctcc
      121 gggagaggcc ctcatcccca gtgtggctcc tcaggacttc tggaggtctc ccatctccag
      181 ctactcaggg tccgtgacac gacatatcag ccaccgggcc aacaacttca aacgccaccc
      241 caagaggagg aagtacattc ggccctctcc acccccaccc cccaacaccc catgtcccat
      301 tgagctggtg gactttgagg acttgcaccc gcagaggtcc ttttgggagc tgctcttcaa
      361 tggctgcatt ctgtttggaa tcgagttcag ctacgccatg gagacagcgt acgtgactcc
      421 agtactcctg caaatgggcc tgcctgacca gctctacagc ctagtgtggt tcatcagccc
      481 catcctcgga ttcttgctgc agcctctgtt gggtgcctgg agtgaccgat gtacctcaag
      541 gtttggaagg agacgccctt tcattcttgt cctggccata ggggcgttgc tgggcctctc
      601 gctcctgctc aatggaaggg acattggtat ggccctggct gacacagcca ccaatcacaa
      661 gtggggcatc ctcctgacgg tatgcggggt ggtgctgatg gacttcagtg cagactcagc
      721 agataacccc agccacgcct acatgatgga cgtgtgtggc ccggtggacc aggaccgggg
      781 cctgaacatc catgccctca tggcgggtct tggaggaggg ttcggctacg tggtcggagg
      841 catccactgg gacaagacca gctttgggag ggccctgggg ggtcagctcc gcgtcatcta
      901 catcttcaca gccataaccc ttagtgtcac caccgtgctc accctggtta gcatccccga
      961 gaggcccctt cggccactgg gagagaagag gacagctatg aagagcccaa gtctcccact
     1021 gcccccctcc ccacctgtct tgttggagga gggggcgggt gacaccctcc cctctactac
     1081 agccaccagc ttgtacgcca gtttctccag ccccatctcg ccacccagcc cgctcacccc
     1141 caagtacggc agcttcatca gcagggacag ttccctcaca ggcatcaatg agttcgcatc
     1201 gtctttcggg acctccaaca tagacagcgt gctcatcgac tgcttcacgg cgggccacga
     1261 taattacttg gctcttccca gcagtgtccc caggcaggcc atcagtgtca gcttcccccg
     1321 ggcccccgat ggtttctact gccaggagag gggactggag aggagagagg ggcccctgac
     1381 cttgggcttg gatggagatg tgctaagggt aggctctctg gacacctcta agccacgggc
     1441 ctcggggatt ctgaagaggc cccagacctt ggctctcccg gacgtggcgg gaggaaacgg
     1501 ccctgaaacc agcaggagaa ggaacgtgac cttcagccaa caggtggcaa acatcctctt
     1561 gaatggtgtg aagtacgaga gtgagctgac gggctccagt gagcagtcgg agcagccgct
     1621 gtctctgcgg cgtctctgtt ccaccatcta caacatgccc agggccctgc gcaatctctg
     1681 tgtcaaccac ttcctggggt ggctctcctt cgagggcatg ctgctcttct acacggactt
     1741 catgggcgag gtggtgtttc agggtgaccc gaaggcgccg cacgcgtcgg aggcgtatca
     1801 gaagtacaac agcggcgtga ccatgggctg ctggggcatg tgcatctacg ccttcagtgc
     1861 ggccttctac tcagccatcc tggagaaact ggaggagtgc ctgagcgtcc gtaccctcta
     1921 cttcatcgcc tacctctcct tcggcctggg gactggactg gccacactct ccaggaacct
     1981 gtacgtggtc ctgtccctct gcaccaccta cggcatcctg ttctccacgc tctgtaccct
     2041 gccctactct ctgctctgcg attactacca gagtaagaag tttgcagggt ccagtgcgga
     2101 cggcacacgg cgcggcatgg gagtagacat ctcgctgctc agctgccagt actttctggc
     2161 tcagatcctc gtgtctctgg tcctggggcc cctgacctcc gctgtgggca gtgccaatgg
     2221 tgtgatgtac ttcgccagcc tcgtgtcctt cctcggctgc ctctactcct ccctgtgtgt
     2281 cacctacgaa atcccctctg ccgatgcagc tgacgaggag cgccagcccc tcctgttgaa
     2341 cgtctgatgt gtcatgatct caaccttgga cttgaaggtg gtctgctgca ggctggcccc
     2401 tgaggaacca aaggccttgg cagccggcca ggctcccagt gggatgtaaa tacaggctaa
     2461 ataaacaaca gcaacaatcg ta
//
