LOCUS       NM_001134715            3453 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus solute carrier family 44 member 2 (Slc44a2),
            mRNA.
ACCESSION   NM_001134715 XM_001077428 XM_343355
VERSION     NM_001134715.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3453)
  AUTHORS   Iwao,B., Yara,M., Hara,N., Kawai,Y., Yamanaka,T., Nishihara,H.,
            Inoue,T. and Inazu,M.
  TITLE     Functional expression of choline transporter like-protein 1 (CTL1)
            and CTL2 in human brain microvascular endothelial cells
  JOURNAL   Neurochem Int 93, 40-50 (2016)
   PUBMED   26746385
REFERENCE   2  (bases 1 to 3453)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 3453)
  AUTHORS   Nakamura,T., Fujiwara,R., Ishiguro,N., Oyabu,M., Nakanishi,T.,
            Shirasaka,Y., Maeda,T. and Tamai,I.
  TITLE     Involvement of choline transporter-like proteins, CTL1 and CTL2, in
            glucocorticoid-induced acceleration of phosphatidylcholine
            synthesis via increased choline uptake
  JOURNAL   Biol Pharm Bull 33 (4), 691-696 (2010)
   PUBMED   20410607
REFERENCE   4  (bases 1 to 3453)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 3453)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   6  (bases 1 to 3453)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC168183.1.
            
            On or before Sep 5, 2008 this sequence version replaced
            XM_001077428.1, XM_343355.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168183.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132300, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3453
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..3453
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /note="solute carrier family 44 member 2"
                     /db_xref="GeneID:363024"
                     /db_xref="RGD:1309680"
     exon            1..108
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..2189
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /note="solute carrier family 44 (choline transporter),
                     member 2"
                     /codon_start=1
                     /product="choline transporter-like protein 2"
                     /protein_id="NP_001128187.1"
                     /db_xref="GeneID:363024"
                     /db_xref="RGD:1309680"
                     /translation="MGKDSQHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVLLFLAI
                     VGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCASPLVLL
                     EFHCPTPQICVKQCPDRYLTFLSARNSRDFDYYKQFCVPGFKNNKGVAEVLRDGECPA
                     VIIPSKPLAQRCFPAIHASKGVLMVGNETTYEDGHGTRKNVTDLVEGAKKANKVLEAR
                     QLAMQIFEDYTVSWYWIVIGLVIAMLLSLMFIVLLRFLAGVMVWVMIVMVILVLGYGI
                     FHCYAEYSRLRGEAGSDVSLVDLGFQTDLRVYLHLRQTWMAFMIILSILEVVIILLLI
                     FLRKRILIAIALIKEASRAVGHVMCSMLYPLVTFFLLCLCIAYWASTSVFLSTSNVAV
                     YKIVDDTPCPLLGKTCNPETFPLNESRQCPNGRCQFAFYGGESTYHRALLGLQIFNAF
                     MFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGS
                     LILAIVQIIRVMLEYLDQRLKAAQNKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIA
                     IYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRI
                     RIVQDTAPPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAE
                     RPYFMSSTLKKLLNKTNKKVAES"
     exon            109..157
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            158..231
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            232..316
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            317..401
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            402..512
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            513..573
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            574..697
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            698..781
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            782..894
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1026
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1126
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1219
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1304
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1564
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1659
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1763
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1837
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..1908
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..1997
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2082
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..3428
                     /gene="Slc44a2"
                     /gene_synonym="RGD1309680"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgcagcgg gtggcggctg tgtcccggag agctccgaca gcccgggcgc cgtcagggct
       61 gcaccgcagg aatggggaag gattcgcagc attactacgg gaagcacggg acgcctcaga
      121 aatatgaccc cacctttaaa ggacccattt acaacagggg atgcacggat atcatttgct
      181 gtgtgttgct cttcctggcc atcgtaggct acgtggctgt gggcatcata gcctggaccc
      241 atggagaccc tcggaaggtg atctacccca ctgatagccg gggcgagttc tgtgggcaaa
      301 agggaacaaa aaatgcggac aaaccattct tgttttactt caacatcgtg aagtgtgcca
      361 gccccctggt cctgctggaa tttcactgtc ccacccctca gatctgcgtg aagcagtgtc
      421 cagaccgcta tctcaccttt ctgagtgcgc gcaactctcg cgactttgac tactacaagc
      481 agttctgtgt gcccggcttc aagaacaata aaggggtagc tgaggtgctc agagatgggg
      541 agtgcccagc ggttatcatc cccagcaaac ccttggccca gcggtgcttc ccggccatcc
      601 atgccagcaa aggggtcctc atggtgggca atgagacgac ctatgaggac ggacacggca
      661 ccaggaagaa tgttacagat ctagtggagg gtgccaaaaa ggccaacaag gttctagagg
      721 cccggcagct cgccatgcag atttttgaag attacactgt atcctggtac tggattgtca
      781 taggtctggt catcgccatg ctgctgagcc tcatgttcat tgtcctgctg cgattcctgg
      841 caggcgtcat ggtctgggtg atgatcgtca tggtgattct ggtacttggc tatggcatat
      901 tccactgcta cgcggagtac tcgagactcc gtggagaggc aggctccgac gtctccctgg
      961 tggaccttgg cttccagacg gacctccgag tgtacctgca cttgaggcag acttggatgg
     1021 ctttcatgat cattttaagc atcctggaag tggtcatcat cctgttactc atctttctgc
     1081 gcaaaaggat cttgatcgcc atagccctca tcaaagaagc cagcagggct gtgggacatg
     1141 tcatgtgctc catgctctac ccactggtga ctttcttcct cttgtgtctc tgcattgcct
     1201 actgggccag cacttctgtc ttcctgtcta cctctaatgt agccgtgtac aagattgttg
     1261 atgacacgcc ctgcccactt ttggggaaaa cctgcaaccc agagaccttc ccattgaatg
     1321 agagccgcca gtgtcctaat ggccgctgtc agtttgcctt ctatggcggc gagtcgacct
     1381 accaccgtgc cctgctgggc ctgcagatct tcaatgcatt catgttcttc tggctagcca
     1441 acttcgtgct agccctgggc caggtgacac tggctggagc ctttgcctcc tattactggg
     1501 ctatgcgaaa gcccgatgac atgcctgcct tccccctctt ctctgctttt ggccgcgcac
     1561 tcaggtacca cacgggctcc ttggcttttg gctctcttat cctagccatc gtgcagatca
     1621 tccgagtgat gctggagtac ctggatcagc gcctgaaagc tgcacagaac aagtttgcca
     1681 agttcctcat ggtctgtctc aagtgctgct tctggtgcct agagaagttt atcaaattcc
     1741 tgaataggaa tgcctacatc atgattgcta tctatggcac caacttctgc acctcagcca
     1801 ggaacgcctt cttcctgctt atgagaaata tcatcagggt ggccgtcctg gacaaagtta
     1861 cagacttcct cttcctgttg ggcaaacttc tgattgtggg tagcgtgggc atcctggcct
     1921 tcttcttctt cacccatcgg atcagaattg tgcaagacac ggccccacct ctcaattatt
     1981 attgggtccc catactgaca gtgatcattg gctcctactt gatcgcgcac ggcttcttca
     2041 gcgtctatgg catgtgcgtg gacacactgt tcctctgttt cttggaggat ctggagagaa
     2101 acgacggctc agccgagagg ccttacttca tgtcttccac tctcaagaaa ctcctgaata
     2161 aaaccaacaa gaaagtagca gaatcctaaa gatgcctgcc gcccagccct ctcaggacgc
     2221 tgtgatccgg tgcttgctgt gcagctgggt cccagttccc agctcatcag acttgtgtaa
     2281 cgtcacatca ctgcctctct gccaccctcc ccgagtcccc atttccaggg acccagagga
     2341 attggggcat ctctgtccta tgccaaaggg cacttgggag ttttcggtgc agccctggga
     2401 aatgggacag aatgggtctc tccaatcctt gctggctcag acggtgccaa tatggcgaag
     2461 cgacttgaag ttgaggatgg gagatggccc gaggatgtgt gcagccaact tctttgtatt
     2521 tcggtaaccc ttctggccaa gaggggaaga ctggatgaga cgagctcaat gaacactagc
     2581 tccaagcttc ctagccagaa taaaactgga tctccacgac tggctgatgt cgcctaaggg
     2641 ccaacaaata acatgtctca ctcttagtcc tttgcagcct agacagacgg taagaggccc
     2701 acctgcttct cttccaccag gctccatagc tgagtggagt caccaagagt gccttcacat
     2761 gtaaccccac ctccagcctg gggtggctgg ggtcacagga aggagtgtgt acccagaact
     2821 ggaggagttt tccagataaa catccatccg ggaggagggc cctgtgcaag gaacgagagc
     2881 ggtggtgggg gttgggagtg gctctggaaa acaggcttct gtacttagat cctacagagt
     2941 acctttgact gatggcttcc aaacggaaaa cttgaggttg gaaaatgagt gaaaataggg
     3001 tctgcctccc cacccctctc tcttccagta atacacactg ccctctttgt gagaggaaag
     3061 aaactgaagt tcacccaagg gatggtttca ggggatgagg tgtgggtgtg ttgtgtattc
     3121 caagttaact aggcctatct ggtttctttc acttgaaact agagactctg tttgccaaac
     3181 ttcttaatct tgggggccag tagactggtt cctcacttta cctatcatat gctaagaccc
     3241 tcccctcacc ccactatggc tatccgtgag ataccaggat gttggaaacc agaggctccc
     3301 agcctggagg cccaggcttt cctatgcctg cctgtgtgcc atcgcgcccc acccttctct
     3361 tgtatgccct gccctgtgct tacgtaattg cattccagcc agttaataaa gtgcctcttg
     3421 tacagataaa aaaaaaaaaa aaaaaaaaaa aaa
//
