LOCUS       NM_001024745            3060 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus solute carrier family 39 member 6 (Slc39a6),
            mRNA.
ACCESSION   NM_001024745 XM_214607
VERSION     NM_001024745.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3060)
  AUTHORS   Teckchandani,A., Toida,N., Goodchild,J., Henderson,C., Watts,J.,
            Wollscheid,B. and Cooper,J.A.
  TITLE     Quantitative proteomics identifies a Dab2/integrin module
            regulating cell migration
  JOURNAL   J Cell Biol 186 (1), 99-111 (2009)
   PUBMED   19581412
REFERENCE   2  (bases 1 to 3060)
  AUTHORS   Chowanadisai,W., Kelleher,S.L. and Lonnerdal,B.
  TITLE     Zinc deficiency is associated with increased brain zinc import and
            LIV-1 expression and decreased ZnT-1 expression in neonatal rats
  JOURNAL   J Nutr 135 (5), 1002-1007 (2005)
   PUBMED   15867272
  REMARK    GeneRIF: Liv-1 (SLC39A6)is localized to the plasma membrane in
            neurons, suggesting that it plays a role in Zn uptake into neurons
REFERENCE   3  (bases 1 to 3060)
  AUTHORS   Taylor,K.M., Morgan,H.E., Johnson,A. and Nicholson,R.I.
  TITLE     Structure-function analysis of a novel member of the LIV-1
            subfamily of zinc transporters, ZIP14
  JOURNAL   FEBS Lett 579 (2), 427-432 (2005)
   PUBMED   15642354
REFERENCE   4  (bases 1 to 3060)
  AUTHORS   Taylor,K.M., Morgan,H.E., Johnson,A., Hadley,L.J. and
            Nicholson,R.I.
  TITLE     Structure-function analysis of LIV-1, the breast cancer-associated
            protein that belongs to a new subfamily of zinc transporters
  JOURNAL   Biochem J 375 (Pt 1), 51-59 (2003)
   PUBMED   12839489
REFERENCE   5  (bases 1 to 3060)
  AUTHORS   Suzuki,A. and Endo,T.
  TITLE     Ermelin, an endoplasmic reticulum transmembrane protein, contains
            the novel HELP domain conserved in eukaryotes
  JOURNAL   Gene 284 (1-2), 31-40 (2002)
   PUBMED   11891044
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097493.1.
            
            On Jun 10, 2005 this sequence version replaced XM_214607.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097493.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN16093049
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3060
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..3060
                     /gene="Slc39a6"
                     /note="solute carrier family 39 member 6"
                     /db_xref="GeneID:291733"
                     /db_xref="RGD:1304664"
     exon            1..157
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            158..910
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..2392
                     /gene="Slc39a6"
                     /note="zinc transporter ZIP6; ZIP-6; zrt- and Irt-like
                     protein 6; solute carrier family 39 (metal ion
                     transporter), member 6; solute carrier family 39 (zinc
                     transporter), member 6"
                     /codon_start=1
                     /product="zinc transporter ZIP6 precursor"
                     /protein_id="NP_001019916.1"
                     /db_xref="GeneID:291733"
                     /db_xref="RGD:1304664"
                     /translation="MATNLSVIMILTFALWVTNPLHELQSTAAFSQTTEKINSNWESG
                     INVDVAVTMQRHHLQQLFYRYGENDSLSVEGFRKLLQNIGIDKIKRVHIHHDHERHSD
                     HERHSDHERHSHRGHAAAGKNSRKAFCPDLDSDNSGKNPNTSQGKGSRPAEHVNGRRN
                     GKESASSSEVTSAVYNTVSEGTHFLETIETPKPGRRTKDINPSTPPSITEKSRVGRLS
                     RLARRKGNDSVSEPRKSFMYSRTSNDNIQECFNATKLLTSHGMSVQALLNATEFNYLC
                     PAIINQIDARSCLIHTASEKKAEIPPKTYSLQIAWLGGFIAISIISFLSLLGVILVPL
                     MNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSH
                     LSAQNLEESSYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDEDV
                     ESKKQLSKYESQLSTNEEKVDTGERPESYLQADSQEPSPFDSQQPTLLEEEEVMIAHA
                     HPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQ
                     RYSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELP
                     HELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGL
                     FMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFEHKIVFRIN
                     F"
     exon            911..1094
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1264
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1483
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1589
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1967
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..2048
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2239
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..3037
                     /gene="Slc39a6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcggccga ggggtagccg ggctcatgat tctgccgctg ctccacgcct cgtaaaggct
       61 tctcagagac cagagctgcg cgggttccca gccccctcgg accgcccgcg gggaaccgaa
      121 cctgcgcgcg gggccgggcg gcgggacacc aggaaaggaa ggtgcaatgg ccacaaattt
      181 atctgtaatc atgatcttga cctttgccct ttgggttaca aatccccttc atgaactaca
      241 atcaacagct gctttctctc agaccactga gaaaattaat tcaaattggg aatctggcat
      301 taatgttgac gtggcagtta ccatgcagcg acatcatctg caacagcttt tctaccgcta
      361 tggagagaat gactccttgt cagttgaagg cttcagaaaa ttacttcaga acataggcat
      421 agataagatt aaaagagtcc acatacacca tgaccacgag cgccactctg accacgagcg
      481 ccactctgac cacgagcgcc actcccaccg aggtcatgct gccgctggga aaaacagtcg
      541 gaaagccttt tgcccagacc ttgactctga taattcaggt aaaaatccga acaccagcca
      601 aggtaaagga tctcgcccag cagagcatgt gaatggcagg aggaatggca aggagagtgc
      661 aagctctagt gaagtgacct cggcagttta caacactgtc tctgaaggaa ctcactttct
      721 agagacaata gagactccaa aacccgggag acgcaccaaa gatataaacc cttctacccc
      781 acccagcatc acagagaaga gccgagtggg ccggctgagc cgactagcta ggaggaaagg
      841 caacgattct gtgagtgagc ccaggaagag cttcatgtat tccagaacct caaatgacaa
      901 tatccaggag tgcttcaatg caacaaaact gctgacatcc catggcatga gcgtccaggc
      961 tctgttgaat gcaacagagt ttaactatct ctgtccagcc attatcaatc aaattgatgc
     1021 tcggtcttgt ctgattcaca cagcaagtga gaagaaggcg gaaatccctc caaagaccta
     1081 ttctttacaa atagcctggc tcggtggctt catagccatt tccatcatca gtttcctgtc
     1141 tctgctggga gtcatcttgg tgccactcat gaaccgagtg ttcttcaagt tcctgctgag
     1201 cttcctcgtg gcgctggccg tggggactct gagtggcgac gctctgttac atcttctccc
     1261 acattctcat gcaagtcatc accacagtca tagccatgaa gaaccagcaa tggaaatgaa
     1321 aagaggtccc ctgttcagcc acctgtcggc tcagaaccta gaagaaagct cctattttga
     1381 ttccacgtgg aaaggtctga cggctctagg gggcttatat ttcatgtttc ttgtggaaca
     1441 cgtcctcacg ctgatcaagc aatttaaaga taagaagaag aagaatcaga agaaacctga
     1501 aaatgatgag gatgtggaga gcaagaagca gctgtccaaa tacgaatctc agctttccac
     1561 aaacgaagag aaggtggaca caggtgaacg acctgaaagc tatctgcaag cggactccca
     1621 agagccctcc ccctttgatt cccagcagcc cacgctgttg gaagaggaag aggtcatgat
     1681 agcccacgca cacccacaag aagtctacaa cgaatacgtg cccaggggct gcaagaacaa
     1741 gtgccactca cacttccacg acacgctggg ccagtctgac gacctcattc accaccacca
     1801 cgactaccac cacattctgc accaccacca ccaccagaac caccaccccc acagccacag
     1861 ccagcgctac tctcgggagg agctgaagga tgctggcatt gccacgttgg cctggatggt
     1921 gatcatgggc gatgggctgc acaatttcag cgacggcctt gccatcggtg ctgctttcac
     1981 tgagggtttg tccagcgggc taagcacctc tgtcgctgtg ttctgtcatg agctgcctca
     2041 tgaactcggt gactttgctg ttttgctaaa ggctggcatg accgtcaagc aggcagtgct
     2101 ctacaatgcc ctgtcagcca tgctggccta tcttggaatg gcaacaggga tattcatcgg
     2161 gcattatgca gaaaatgttt ccatgtggat atttgccctc actgctggct tgttcatgta
     2221 tgtcgctctg gtcgacatgg tacccgagat gctgcacaat gatgccagtg atcacggatg
     2281 cagccgctgg ggatatttct tcctgcagaa tgctgggata cttctgggtt ttggaattat
     2341 gttactcatt tccatatttg agcataaaat tgtgtttcgt ataaatttct aattaggttc
     2401 taaaccctgg agcagcttat agaagtattg ttgtctgtag ttggatagat ggtagaaatg
     2461 cgttcgcacg ctgtgacaca gcagttaaaa ctagtgggct ttgcgatttc tctatcaaat
     2521 gttgccattt gttatgctta tcaagtcagc tccgttgggt aacatagcgg tacgtgttaa
     2581 tatttaagtt attctgtttt ggaaatgtaa attacatgtg cgatccacca gtattgcccg
     2641 gtttactgtg tgtctgggca tgccatgttc tgtatgtttt agagaaagtg tcttttatgc
     2701 tcctttgtac agctttagca ttggttccct gctggagttg ggcccctgct catggtgagc
     2761 aagaatgacc acaaaaccca agacaccaac agttcacaca gtgtagccaa gaaacggaag
     2821 gaaaggattg gggaggtgtg tattgcttcg aaaaatcaca agattggtta taatgtagat
     2881 ttgttttaaa ggggcgtgtt tagttcagcg tacttcatga acatctgtcg gattgttaat
     2941 gttcctgtaa aacaagtgag cacttttgat acacttcctc tggttgtaca tttgtgtaat
     3001 agagaagtct aaatatatta atccaagcag tgtgtcaaaa aaaaaaaaaa aaaaaaaaaa
//
