LOCUS       NM_001399258            2294 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus solute carrier family 39 member 13 (Slc39a13),
            transcript variant 1, mRNA.
ACCESSION   NM_001399258 XM_006234501
VERSION     NM_001399258.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Sun,Q., Zhong,W., Zhang,W., Li,Q., Sun,X., Tan,X., Sun,X., Dong,D.
            and Zhou,Z.
  TITLE     Zinc deficiency mediates alcohol-induced apoptotic cell death in
            the liver of rats through activating ER and mitochondrial cell
            death pathways
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 308 (9), G757-G766 (2015)
   PUBMED   25767260
REFERENCE   2  (bases 1 to 2294)
  AUTHORS   Bin,B.H., Fukada,T., Hosaka,T., Yamasaki,S., Ohashi,W., Hojyo,S.,
            Miyai,T., Nishida,K., Yokoyama,S. and Hirano,T.
  TITLE     Biochemical characterization of human ZIP13 protein: a
            homo-dimerized zinc transporter involved in the spondylocheiro
            dysplastic Ehlers-Danlos syndrome
  JOURNAL   J Biol Chem 286 (46), 40255-40265 (2011)
   PUBMED   21917916
REFERENCE   3  (bases 1 to 2294)
  AUTHORS   Guo,L., Hu,X., Xu,T., Qi,X., Wan,Y., Liu,X., Jiang,Y. and Zhang,L.
  TITLE     Over-expression of Zip-13 mRNA in kidney and lung during dietary
            zinc deficiency in Wistar rats
  JOURNAL   Mol Biol Rep 38 (3), 1869-1874 (2011)
   PUBMED   20859692
  REMARK    GeneRIF: Zip-13 shows an up-regulation (P < 0.05) in
            zinc-deficiency group both in kidney and lung.
REFERENCE   4  (bases 1 to 2294)
  AUTHORS   Giunta,C., Elcioglu,N.H., Albrecht,B., Eich,G., Chambaz,C.,
            Janecke,A.R., Yeowell,H., Weis,M., Eyre,D.R., Kraenzlin,M. and
            Steinmann,B.
  TITLE     Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an
            autosomal-recessive entity caused by mutations in the zinc
            transporter gene SLC39A13
  JOURNAL   Am J Hum Genet 82 (6), 1290-1305 (2008)
   PUBMED   18513683
REFERENCE   5  (bases 1 to 2294)
  AUTHORS   Fukada,T., Civic,N., Furuichi,T., Shimoda,S., Mishima,K.,
            Higashiyama,H., Idaira,Y., Asada,Y., Kitamura,H., Yamasaki,S.,
            Hojyo,S., Nakayama,M., Ohara,O., Koseki,H., Dos Santos,H.G.,
            Bonafe,L., Ha-Vinh,R., Zankl,A., Unger,S., Kraenzlin,M.E.,
            Beckmann,J.S., Saito,I., Rivolta,C., Ikegawa,S., Superti-Furga,A.
            and Hirano,T.
  TITLE     The zinc transporter SLC39A13/ZIP13 is required for connective
            tissue development; its involvement in BMP/TGF-beta signaling
            pathways
  JOURNAL   PLoS One 3 (11), e3642 (2008)
   PUBMED   18985159
  REMARK    Erratum:[PLoS One. 2008;3(11). doi:
            10.1371/annotation/a6c35a12-e8eb-43a0-9d00-5078fa6da1bb]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 5, 2022 this sequence version replaced XM_006234501.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.12013.1,
                                           SRR26643295.14156.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN09345330,
                                           SAMN12840108 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                JAXUCZ010000003.1  97502975-97503044   c
            71-379              JAXUCZ010000003.1  97501225-97501533   c
            380-493             JAXUCZ010000003.1  97499090-97499203   c
            494-615             JAXUCZ010000003.1  97498664-97498785   c
            616-717             JAXUCZ010000003.1  97497990-97498091   c
            718-807             JAXUCZ010000003.1  97497801-97497890   c
            808-858             JAXUCZ010000003.1  97497125-97497175   c
            859-991             JAXUCZ010000003.1  97496762-97496894   c
            992-1091            JAXUCZ010000003.1  97496524-97496623   c
            1092-2294           JAXUCZ010000003.1  97495229-97496431   c
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q24"
     gene            1..2294
                     /gene="Slc39a13"
                     /note="solute carrier family 39 member 13"
                     /db_xref="GeneID:295928"
                     /db_xref="RGD:1304695"
     exon            1..70
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            71..379
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1167
                     /gene="Slc39a13"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; zinc transporter ZIP13; ZIP-13; zrt- and
                     Irt-like protein 13; solute carrier family 39 (metal ion
                     transporter), member 13; solute carrier family 39 (zinc
                     transporter), member 13"
                     /codon_start=1
                     /product="zinc transporter ZIP13 isoform 1 precursor"
                     /protein_id="NP_001386187.1"
                     /db_xref="GeneID:295928"
                     /db_xref="RGD:1304695"
                     /translation="MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAA
                     ACRLDSKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQSEAG
                     AWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQSLQRQQQLGLWVIAGFL
                     TFLALEKMFLNCKEEDPSQAPSKDPTAAALNGGHCLAQPAAEPGLRAVVRNLKVSGYL
                     NLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWT
                     AAKLQFSTALGGLLGACFAICTQSPKGVEETVVWTLPFTSGGFLYVALVNVLPDLLEE
                     DDPWHSLQQVLLLCSGIVVMVLLSLFVE"
     exon            380..493
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            494..615
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            616..717
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            718..807
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            808..858
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            859..991
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1091
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..2294
                     /gene="Slc39a13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatggcccg gcccgcccgg agcgctgcat ctgctgccgc tgccacctct gccacctctg
       61 ccgctgcacg tgcccggcat gcctggatgt ccctgccctg gctgtggtat ggcaggccag
      121 aggctcctct tcctcactgt ccttgccctg gagctcctgg aaagggctgg aggttcccag
      181 ccagccctcc ggagcctggg ggctgcagct gcctgtcgcc tggatagtaa agaaagcgag
      241 tcctgggggg ctctgctgag tggggagcga ctggacacct ggatctgctc cctcttgggc
      301 tctctcatgg ttgggctcag tggggttttc cccttgctgg tcattcccct ggagatgggg
      361 accatgttac aatcagaagc tggagcctgg cgcctgaagc agctgctcag ctttgcctta
      421 ggtggactcc tgggcaatgt gtttctgcac ttgctgccag aggcgtgggc ctacacctgt
      481 aacatcagcc ccggtgttga agggcagagt ctgcagcgac agcaacaact ggggctgtgg
      541 gtcatcgctg gcttcctgac cttcctggca ttggagaaga tgttcctcaa ctgcaaggag
      601 gaggacccta gccaggcccc cagcaaagac cccactgctg ccgcgctcaa tggaggccac
      661 tgtctggccc agccggctgc agagcccggc ctgagagccg tggtccggaa cctcaaagtc
      721 agtggctatc tcaacctgct ggccaatacc attgacaact tcacccatgg gctggctgtg
      781 gctgccagct tccttgtgag caaaaagatt gggcttctaa ccaccatggc catcctcctg
      841 catgagatcc cccatgaggt gggtgacttt gctatcctgc tccgggctgg ctttgaccga
      901 tggaccgcag ccaagctaca gttttctaca gccctgggag gccttctggg ggcctgcttt
      961 gccatctgta cgcaatcccc caaaggagta gaggagacgg tggtctggac cctgcccttt
     1021 acctcaggag gctttctcta tgttgccctg gtgaatgtgc tacctgacct cttggaggaa
     1081 gatgacccat ggcactccct gcagcaggtg ctgctgctct gctccggtat cgtggtgatg
     1141 gtgctgctct cgttgttcgt tgaataacca ctgctgacag cccactctgc atagcaagca
     1201 ataagagact ccaatttgtt ctgtgactat gtgtgtgaga ggcagagggt gaatggtaga
     1261 gccagcctct cactggacag ggagtgtgtg gtgtgcacgt gcagccagag tgtgagagag
     1321 agaccgacac tgtgatctct gggtgcagaa cccagagccc aacgtagcat ctgcccggcc
     1381 accccactgt cacctagcag caaggaatgg cagtcccggt gccagcacaa gactcacttc
     1441 tcacttgaca aagaaaccag ccccatgagc ccagggctac agcttgaaga gggctatagc
     1501 ccaaagttgt tcctcctggg ctctagccaa gagagaagag aaggaaaaag aaaatatcca
     1561 aacaaaagct ctctgctcac atatctaagt tgcccaaagc accttagaag cagaggctac
     1621 acagcttttc tctgctatcc attttcctta cccttcctac accacctcta cagccaaaga
     1681 agggggaggt gggtgcttgt agccccagcc ccacttagca ctgatgtcct acccctcccc
     1741 agcactgagc aggcaagtgc tccaagacct cttcctaggg acagccagcc tggctggcac
     1801 atttccccaa caaatgctcc ctggccacac gggcagctct caccacctcc ggctgccaaa
     1861 cagcagtctg cgagtcagta agtagtccga ggctagcagt ctcccagcca gctctcccgg
     1921 atgctcctgc cagcacaggg ttcagcaggc atgcatgccc caggcagaga gaatgagcca
     1981 tgctgccctt tcctgctcag ggccccttgt cctttgggtt aagtgtaaga cgggggtggt
     2041 gaaggctcca cattgtcagt gctcaggaat gtgaactggg agaacgctga agccataatc
     2101 cccaactatt tcccttggct gatgcccagg tactcagctg gcccaatcta cagccagact
     2161 ccagccctgc tgctcaactg tggacgttag agaagaggcc actgaagaat ctgaatgatt
     2221 gcacagttac tctgtggttc atcttatctg taaatatttg ttctgtagat ataataaata
     2281 ttacctagat tggc
//
