LOCUS       NM_001134577            2422 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus solute carrier family 39 member 1 (Slc39a1),
            mRNA.
ACCESSION   NM_001134577 XM_001075087 XM_342286
VERSION     NM_001134577.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2422)
  AUTHORS   Pan R and Liu KJ.
  TITLE     ZNT-1 Expression Reduction Enhances Free Zinc Accumulation in
            Astrocytes After Ischemic Stroke
  JOURNAL   Acta Neurochir Suppl 121, 257-261 (2016)
   PUBMED   26463958
  REMARK    GeneRIF: Hypoxia/reoxygenation did not change the ZIP-1 level in
            astrocytes.
REFERENCE   2  (bases 1 to 2422)
  AUTHORS   Belloni-Olivi L, Marshall C, Laal B, Andrews GK and Bressler J.
  TITLE     Localization of zip1 and zip4 mRNA in the adult rat brain
  JOURNAL   J Neurosci Res 87 (14), 3221-3230 (2009)
   PUBMED   19530166
  REMARK    GeneRIF: The localization of zip1 and zip4 was examined in the
            brains of adult rats
REFERENCE   3  (bases 1 to 2422)
  AUTHORS   Kim OJ, Ariano MA, Namkung Y, Marinec P, Kim E, Han J and Sibley
            DR.
  TITLE     D2 dopamine receptor expression and trafficking is regulated
            through direct interactions with ZIP
  JOURNAL   J Neurochem 106 (1), 83-95 (2008)
   PUBMED   18346199
REFERENCE   4  (bases 1 to 2422)
  AUTHORS   Dufner-Beattie J, Huang ZL, Geiser J, Xu W and Andrews GK.
  TITLE     Mouse ZIP1 and ZIP3 genes together are essential for adaptation to
            dietary zinc deficiency during pregnancy
  JOURNAL   Genesis 44 (5), 239-251 (2006)
   PUBMED   16652366
REFERENCE   5  (bases 1 to 2422)
  AUTHORS   Dufner-Beattie J, Langmade SJ, Wang F, Eide D and Andrews GK.
  TITLE     Structure, function, and regulation of a subfamily of mouse zinc
            transporter genes
  JOURNAL   J Biol Chem 278 (50), 50142-50150 (2003)
   PUBMED   14525987
REFERENCE   6  (bases 1 to 2422)
  AUTHORS   Franklin RB, Ma J, Zou J, Guan Z, Kukoyi BI, Feng P and Costello
            LC.
  TITLE     Human ZIP1 is a major zinc uptake transporter for the accumulation
            of zinc in prostate cells
  JOURNAL   J Inorg Biochem 96 (2-3), 435-442 (2003)
   PUBMED   12888280
REFERENCE   7  (bases 1 to 2422)
  AUTHORS   Gaither LA and Eide DJ.
  TITLE     The human ZIP1 transporter mediates zinc uptake in human K562
            erythroleukemia cells
  JOURNAL   J Biol Chem 276 (25), 22258-22264 (2001)
   PUBMED   11301334
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000069.1.
            
            [WARNING] On Mar 27, 2024 this sequence was replaced by
            NM_001134577.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001134577.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168649.1, SRR8487227.161620.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                JACYVU010000069.1  42175903-42175947
            46-263              JACYVU010000069.1  42176640-42176857
            264-394             JACYVU010000069.1  42177000-42177130
            395-2422            JACYVU010000069.1  42179453-42181480
FEATURES             Location/Qualifiers
     source          1..2422
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2422
                     /gene="Slc39a1"
                     /note="solute carrier family 39 member 1"
                     /db_xref="GeneID:361986"
                     /db_xref="RGD:1305241"
     exon            1..45
                     /gene="Slc39a1"
                     /inference="alignment:Splign:2.1.0"
     exon            46..263
                     /gene="Slc39a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1051
                     /gene="Slc39a1"
                     /note="solute carrier family 39 (zinc transporter), member
                     1"
                     /codon_start=1
                     /product="zinc transporter ZIP1"
                     /protein_id="NP_001128049.1"
                     /db_xref="GeneID:361986"
                     /db_xref="RGD:1305241"
                     /translation="MGPWGEPELLVWRPEAIASEPSVPVGLEVKLGALVLLLLLTLIC
                     SLVPVCVLRRSGANHEASASGQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALEA
                     LHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQSSPPHPEETRALLGTVNGGPQHWH
                     DGPGIPQASGTPAAPSALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHK
                     GILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLE
                     GMAAGTFLYITFLEILPQELATSEQRILKVILLLAGFALLTGLLFVQV"
     exon            264..394
                     /gene="Slc39a1"
                     /inference="alignment:Splign:2.1.0"
     exon            395..2422
                     /gene="Slc39a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgaggccgga accgagccac agcgatggag tgagaccctc cggaggtcga agagtcactg
       61 agttatccca accaccatgg ggccctgggg ggagcccgag ctcctggtgt ggcgcccaga
      121 agcgatcgca tcggagccct cggtgccagt ggggctggag gtgaagctgg gggccctggt
      181 gctgctgttg ctgctgacac tcatctgcag cctggtacct gtctgtgtgc ttcgaaggtc
      241 aggcgctaac catgaagcct ctgcttcagg ccagaaagct ttaagcctag tgagctgctt
      301 cgcaggagga gtcttcctgg ctacctgtct tctggacttg ctgcctgact acctggctgc
      361 catagatgag gccttggagg ctcttcatgt gacgcttcag ttccccttgc aagagttcat
      421 cctggccatg ggtttcttcc tggtgttggt gatggagcag atcacactgg cttataagga
      481 gcagtccagt ccaccacatc cggaagagac gagagctcta ctgggaacag tgaatggtgg
      541 gcctcaacat tggcatgatg gaccagggat cccccaggcc agcggaaccc cagcagctcc
      601 ctcagccctg cgtgcctgtg tactggtctt ctccttagcc ttgcactctg tatttgaggg
      661 cctggctgta gggttgcaga gagacagggc tcgagcaatg gagctgtgcc tagctttgct
      721 gctccacaag ggtatcctgg cagtcagtct gtccctgcgg cttctacaga gccacctacg
      781 agcgcaggtg gtggctggct gtgggatcct cttctcctgt atgacacctc tgggcattgg
      841 gctgggtgca gctctggcag agtcagctgg gcctctccac cagctggccc agtctgttct
      901 ggagggcatg gcagctggca ccttcctcta tatcaccttc ctggaaatcc taccccagga
      961 gttggccacg tctgagcaga ggatcctcaa ggtcattctg ctcctagcag gctttgccct
     1021 gctcaccggc ctgctctttg tccaagtcta aggtgcttcg agagaaaagg caggggaggt
     1081 tgactatcag gtgcccctgt cctccctgcc cttctcaatt tgtgggaaat tgaaaggaat
     1141 ggagaaagga agtagtgagg accaaagagt tctcttgaga ggtagggatg ggacatttgg
     1201 actacgaata atgagatgga agtgagcaga gaagaggcaa gccccagacc caaagaatta
     1261 agtgatagcc aagttactac ggacatgatc agtgggcatt aaaatgaggc agaccgctac
     1321 aatcagaggt caggctctac atctaagaga caagctgaca gaagaactga gttaggtatc
     1381 cagctgcttt gggataaaga tgcagaggct ataagtcaaa gccagtatcc tattggttct
     1441 agcccatttc accactctgc tgattgaagt ggttcctcct actgtcttgt ctcctaatct
     1501 tctatttctc tcttgtcttc caccaaggga ctagtgccaa atggtctctt tgccattttt
     1561 cgtaatttat ctggcccttc ttgtccttgg gtttctctgt gtagccttgg ctgtcctgga
     1621 actcactctg tagaccagcc tgggcttcag tttacagaga tccatctgcc tctgcctccc
     1681 taatgctggg attaaagggg tgctgggcca ccactgccta gctcactagt ctgttttttt
     1741 tttttttttt tttttttttt ttttttcttt ttctggagct ggggaccgaa cccagggcct
     1801 tgcgcatgct aggcaagcgc tctaccactg agctaaatcc ccaaccccac tagtctgttt
     1861 ttaaagtgcc aaatacccgt ccacccactc accctttggg tttttgtttg ctttctaccc
     1921 cccccccccc cccccccccc ccccccgcca gggtttctct gtatagctct ggttgtcctg
     1981 gcctcaaact cagagctctg actgcctctg cctcctgagc actgggatta aaggtgtgca
     2041 gcaccatggg ttgctcacct gccccttttc tgaaagcaca gtgatgaggt gatgggtcag
     2101 tggaggagac ctatttgctc tttatttagg ccccacaatt tggggtgggg cagaaatgtt
     2161 tgctgaactg gtctggaatg agaaaagtag gtactgatac cagccactac agaaagtgga
     2221 catggtgggc caaacctaga taataacaat aacctgccaa aactttatat ctgaggagcc
     2281 cggggtgggg agacagattc cccccacccc caggattatt tttggggagg gagggctgtg
     2341 catagggctg tactctgtag aatctatttt actaactgac ctgttttggg acatattacc
     2401 caaataaaga tgtttctata ca
//
