LOCUS       NM_001035251            1807 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 38, member 9 (Slc38a9),
            mRNA.
ACCESSION   NM_001035251 XM_226760
VERSION     NM_001035251.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1807)
  AUTHORS   Jung,J.W., Macalino,S.J.Y., Cui,M., Kim,J.E., Kim,H.J., Song,D.G.,
            Nam,S.H., Kim,S., Choi,S. and Lee,J.W.
  TITLE     Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1
            Signaling
  JOURNAL   Cell Metab 29 (6), 1306-1319 (2019)
   PUBMED   30956113
REFERENCE   2  (bases 1 to 1807)
  AUTHORS   Wyant,G.A., Abu-Remaileh,M., Wolfson,R.L., Chen,W.W., Freinkman,E.,
            Danai,L.V., Vander Heiden,M.G. and Sabatini,D.M.
  TITLE     mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino
            Acids from Lysosomes and Use Protein as a Nutrient
  JOURNAL   Cell 171 (3), 642-654 (2017)
   PUBMED   29053970
REFERENCE   3  (bases 1 to 1807)
  AUTHORS   Rebsamen,M., Pochini,L., Stasyk,T., de Araujo,M.E., Galluccio,M.,
            Kandasamy,R.K., Snijder,B., Fauster,A., Rudashevskaya,E.L.,
            Bruckner,M., Scorzoni,S., Filipek,P.A., Huber,K.V., Bigenzahn,J.W.,
            Heinz,L.X., Kraft,C., Bennett,K.L., Indiveri,C., Huber,L.A. and
            Superti-Furga,G.
  TITLE     SLC38A9 is a component of the lysosomal amino acid sensing
            machinery that controls mTORC1
  JOURNAL   Nature 519 (7544), 477-481 (2015)
   PUBMED   25561175
REFERENCE   4  (bases 1 to 1807)
  AUTHORS   Wang,S., Tsun,Z.Y., Wolfson,R.L., Shen,K., Wyant,G.A.,
            Plovanich,M.E., Yuan,E.D., Jones,T.D., Chantranupong,L., Comb,W.,
            Wang,T., Bar-Peled,L., Zoncu,R., Straub,C., Kim,C., Park,J.,
            Sabatini,B.L. and Sabatini,D.M.
  TITLE     Metabolism. Lysosomal amino acid transporter SLC38A9 signals
            arginine sufficiency to mTORC1
  JOURNAL   Science 347 (6218), 188-194 (2015)
   PUBMED   25567906
REFERENCE   5  (bases 1 to 1807)
  AUTHORS   denDekker,A.D., Xu,X., Vaughn,M.D., Puckett,A.H., Gardner,L.L.,
            Lambring,C.J., Deschenes,L. and Samuelson,D.J.
  TITLE     Rat Mcs1b is concordant to the genome-wide association-identified
            breast cancer risk locus at human 5q11.2 and MIER3 is a candidate
            cancer susceptibility gene
  JOURNAL   Cancer Res 72 (22), 6002-6012 (2012)
   PUBMED   22993404
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105869.1.
            
            On Nov 1, 2005 this sequence version replaced XM_226760.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105869.1, JQ013729.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132296, SAMD00132297
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1807
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..1807
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /note="solute carrier family 38, member 9"
                     /db_xref="GeneID:310091"
                     /db_xref="RGD:1311881"
     exon            1..139
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1709
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /note="putative sodium-coupled neutral amino acid
                     transporter 9"
                     /codon_start=1
                     /product="neutral amino acid transporter 9"
                     /protein_id="NP_001030328.1"
                     /db_xref="GeneID:310091"
                     /db_xref="RGD:1311881"
                     /translation="MANVDSDSRHLISEVEHEVNPGPMNIQFDSSDLRSKRPFYIEPT
                     NIVNVNDVIQKVSDHAAAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGS
                     AYKLKSYTEGYRKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIVLMGLLT
                     LYCCYRVVKSRSMIVTSDTTTWEYPDVCKHYFGSFGQWSSLLFSLVSLIGAMIVYWVL
                     MSNFLFNTGKFIFNFIHHINDTDTVLSTNNSSPVICPSAGSGHPDNSSMIFYNSDTEV
                     RLFERWWDKSKTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFIVTLKAIRL
                     GFHLEFHWFAPTEFFVPEIRAQFPQLTGVLTLAFFIHNCIITLLKNNKNQENNVRDLC
                     IAYMLVTLTYLYIGVLVFASFPSPPLPKDCIEQNFLDNFPSSDTLSFIARICLLFQMM
                     TVYPLLGYLARVQLLGHIFGDIYPSIFHVLILNLIIVGAGVTMACFYPNIGGIIRYSG
                     AACGLAFVFIYPSLIYILSQHQEERLTWPKLVFHIIIIILGLANLIAQFFM"
     exon            140..272
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            273..394
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            395..458
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            459..552
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            553..723
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            724..783
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            784..975
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1083
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1190
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1304
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1453
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1543
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1783
                     /gene="Slc38a9"
                     /gene_synonym="RGD1311881"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccccagt gcctggaatc tgagaaaaaa tggcaaacgt ggatagtgac tctaggcatc
       61 ttatctctga ggtagaacat gaagtgaatc ccggacctat gaatatccag tttgactcct
      121 cagacctaag atctaaaagg cctttctata tagagcctac caacatcgtc aatgtgaatg
      181 atgtcattca gaaggtcagc gaccatgctg ctgctatgaa caagcggatt cattactaca
      241 gccggctcac cactcctgca gacaaggcac tgattgctcc agaccacgta gttcctgctc
      301 cagaggaatg ctatgtgtac agtccattgg gctctgccta taaacttaag agttacactg
      361 aaggctatcg taaaaacacc agcttagtta ctatttttat gatctggaat accatgatgg
      421 ggacatctat actaagtatt ccttggggca taaaacaggc tggatttact actgggatgt
      481 gtgtcatcgt gctgatgggc cttctaacac tttactgctg ctatagagtg gtgaagtccc
      541 ggagtatgat agttacatcg gacacaacta cctgggaata tccagatgtc tgcaaacatt
      601 actttggctc ttttgggcaa tggtcaagtc tccttttctc cttggtgtct ctcattggag
      661 caatgatagt ttattgggtg cttatgtcta attttctttt taatactgga aagtttattt
      721 ttaattttat tcatcacatt aatgacacag acactgtact gagcaccaat aatagcagcc
      781 ctgtgatctg tccaagcgcc gggagtggcc atcctgacaa cagctccatg atcttctaca
      841 acagtgacac ggaggtgcgg ctgtttgaga ggtggtggga caagtccaag acagtgccct
      901 tctaccttat agggctcctc ttgccgctgc tcaacttcaa gtctccttcg ttcttctcca
      961 aatttaatat cctgggtacg gtatctgtcc tctatttgat tttcattgtt accctgaagg
     1021 ctattcgctt aggattccat ctggaatttc actggtttgc gccaacagaa ttttttgtac
     1081 cagagataag agctcagttt ccacagctga caggggtgct tactctggcc ttctttattc
     1141 acaattgtat catcacactc ttgaaaaaca acaagaacca agaaaataat gtgagagacc
     1201 tgtgcattgc ttatatgctg gtgacattga cctatctcta tattggtgtc ctggtttttg
     1261 cctcattccc ttcacctcca ttacccaaag attgtattga acagaacttc ttggacaact
     1321 tccccagcag tgacaccctg tccttcattg cacggatatg cctgctcttc cagatgatga
     1381 ctgtgtaccc actcttaggc tacttggctc gcgttcagct cctgggccat atcttcggtg
     1441 acatttatcc tagcattttc catgtgctga ttcttaactt aattatcgtg ggtgctggag
     1501 tgaccatggc ctgtttctac ccaaacatag gagggatcat aaggtactcg ggagcagcgt
     1561 gcggcctggc tttcgtgttc atataccctt ctctcatcta tatactctcc cagcaccaag
     1621 aggagcgtct gacatggcct aagttagtgt ttcacatcat catcatcatt ttgggcctgg
     1681 cgaacctgat tgctcagttt ttcatgtgaa aaccgttttc tcaagattcc tcatggtgtt
     1741 ctgaaccttg gcaacggttc tgcataaaag aacttgaaaa tgcaaaaaaa aaaaaaaaaa
     1801 aaaaaaa
//
