LOCUS       NM_001416485            2379 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 37 member 4 (Slc37a4),
            transcript variant 3, mRNA.
ACCESSION   NM_001416485 XM_039080966
VERSION     NM_001416485.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2379)
  AUTHORS   Pan,C.J., Chen,S.Y., Jun,H.S., Lin,S.R., Mansfield,B.C. and
            Chou,J.Y.
  TITLE     SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate
            antiporters
  JOURNAL   PLoS One 6 (9), e23157 (2011)
   PUBMED   21949678
REFERENCE   2  (bases 1 to 2379)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2379)
  AUTHORS   Chen,S.Y., Pan,C.J., Nandigama,K., Mansfield,B.C., Ambudkar,S.V.
            and Chou,J.Y.
  TITLE     The glucose-6-phosphate transporter is a phosphate-linked
            antiporter deficient in glycogen storage disease type Ib and Ic
  JOURNAL   FASEB J 22 (7), 2206-2213 (2008)
   PUBMED   18337460
REFERENCE   4  (bases 1 to 2379)
  AUTHORS   Walker,E.A., Ahmed,A., Lavery,G.G., Tomlinson,J.W., Kim,S.Y.,
            Cooper,M.S., Ride,J.P., Hughes,B.A., Shackleton,C.H.L.,
            McKiernan,P., Elias,E., Chou,J.Y. and Stewart,P.M.
  TITLE     11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by
            Intracellular Glucose 6-Phosphate Provides Evidence for a Novel
            Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal
            Axis Function
  JOURNAL   J Biol Chem 282 (37), 27030-27036 (2007)
   PUBMED   17588937
REFERENCE   5  (bases 1 to 2379)
  AUTHORS   Marcolongo,P., Piccirella,S., Senesi,S., Wunderlich,L., Gerin,I.,
            Mandl,J., Fulceri,R., Banhegyi,G. and Benedetti,A.
  TITLE     The glucose-6-phosphate transporter-hexose-6-phosphate
            dehydrogenase-11beta-hydroxysteroid dehydrogenase type 1 system of
            the adipose tissue
  JOURNAL   Endocrinology 148 (5), 2487-2495 (2007)
   PUBMED   17303657
  REMARK    GeneRIF: adipocytes are equipped with a functional
            G6PT-hexose-6-phosphate dehydrogenase-11beta-hydroxysteroid
            dehydrogenase type 1 system
REFERENCE   6  (bases 1 to 2379)
  AUTHORS   Pan,C.J., Lin,B. and Chou,J.Y.
  TITLE     Transmembrane topology of human glucose 6-phosphate transporter
  JOURNAL   J Biol Chem 274 (20), 13865-13869 (1999)
   PUBMED   10318794
REFERENCE   7  (bases 1 to 2379)
  AUTHORS   Lin,B., Annabi,B., Hiraiwa,H., Pan,C.J. and Chou,J.Y.
  TITLE     Cloning and characterization of cDNAs encoding a candidate glycogen
            storage disease type 1b protein in rodents
  JOURNAL   J Biol Chem 273 (48), 31656-31660 (1998)
   PUBMED   9822626
REFERENCE   8  (bases 1 to 2379)
  AUTHORS   Parker,J.C., VanVolkenburg,M.A., Levy,C.B., Martin,W.H., Burk,S.H.,
            Kwon,Y., Giragossian,C., Gant,T.G., Carpino,P.A., McPherson,R.K.,
            Vestergaard,P. and Treadway,J.L.
  TITLE     Plasma glucose levels are reduced in rats and mice treated with an
            inhibitor of glucose-6-phosphate translocase
  JOURNAL   Diabetes 47 (10), 1630-1636 (1998)
   PUBMED   9753303
REFERENCE   9  (bases 1 to 2379)
  AUTHORS   Gerin,I., Veiga-da-Cunha,M., Achouri,Y., Collet,J.F. and Van
            Schaftingen,E.
  TITLE     Sequence of a putative glucose 6-phosphate translocase, mutated in
            glycogen storage disease type Ib
  JOURNAL   FEBS Lett 419 (2-3), 235-238 (1997)
   PUBMED   9428641
REFERENCE   10 (bases 1 to 2379)
  AUTHORS   Khan,A., Low,H. and Efendic,S.
  TITLE     Effects of fasting and refeeding on the activity of hepatic
            glucose-6-phosphatase in rats
  JOURNAL   Acta Physiol Scand 124 (4), 591-596 (1985)
   PUBMED   2996302
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Feb 3, 2023 this sequence version replaced XM_039080966.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.34739.1,
                                           SRR22582416.1615316.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-383               JAXUCZ010000008.1  53620208-53620590
            384-728             JAXUCZ010000008.1  53621414-53621758
            729-961             JAXUCZ010000008.1  53622394-53622626
            962-1205            JAXUCZ010000008.1  53622947-53623190
            1206-1364           JAXUCZ010000008.1  53623649-53623807
            1365-1450           JAXUCZ010000008.1  53623999-53624084
            1451-1564           JAXUCZ010000008.1  53624562-53624675
            1565-1703           JAXUCZ010000008.1  53625197-53625335
            1704-2379           JAXUCZ010000008.1  53625435-53626110
FEATURES             Location/Qualifiers
     source          1..2379
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..2379
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /note="solute carrier family 37 member 4"
                     /db_xref="GeneID:29573"
                     /db_xref="RGD:62066"
     exon            1..383
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            384..728
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             581..1870
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /note="glucose-6-phosphatase, transport protein 1; solute
                     carrier family 37 (glycerol-6-phosphate transporter),
                     member 4; glucose-6-phosphate translocase; solute carrier
                     family 37 (glucose-6-phosphate transporter), member 4"
                     /codon_start=1
                     /product="glucose-6-phosphate exchanger SLC37A4"
                     /protein_id="NP_001403414.1"
                     /db_xref="GeneID:29573"
                     /db_xref="RGD:62066"
                     /translation="MAAQGYGYYRTVIFTAMFGGYSLYYFNRKTFSFVMPSLVDEIAL
                     DKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTA
                     FAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILA
                     QSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQ
                     DLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVG
                     SIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKIWILVL
                     GAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYS
                     WSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE"
     exon            729..961
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1205
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1364
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1450
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1564
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1703
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..2379
                     /gene="Slc37a4"
                     /gene_synonym="G6pt1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcccgatga ctgcccttcc gggatggcga cagttccgcg gccccaggac cgcggtcttg
       61 tagatgccgc gccctcgtgg ctgcagcgct cagtctccgt agctctcctg ctcctgtccc
      121 caggacccgc agttcccaac ctggagtcgg gtgtcccggg tagcttgagg acaccgggtg
      181 cttggcaggt gcggagcggc gccgcctgac catcctgact ggcagagcct aggctgccag
      241 agcgaggggc ctctcgaggc tacgtgcggc tccctcgcgc ctacgccttc tgctccagcg
      301 gctgctcaga ggagcagaaa gctgcggtgg cgtgttcagg ggctcacacc cttgcaatac
      361 ggatgcccta ctgatgccgc agggacactg ggttcctagg ttgctgcccc aggcttaatg
      421 attgtccaga aggcggctat aaagagcctg ggtggaggag agagcgcaga aaaacacagc
      481 tcagcagatc cgggcactgg agagggagct gcaagcagga gcagtcaaga gtgtggtcag
      541 aagcaccgtg agtggaccag cagggccggc tttttctacc atggcggccc aaggctatgg
      601 ctattaccgc actgtcatat tcacagccat gttcggaggc tacagccttt actacttcaa
      661 ccgcaaaacc ttctcttttg tcatgccctc cttggtggat gagatcgctc tggacaagga
      721 cgatttgggg ctcatcacga gcagccagtc ggcagcctac gccatcagca agtttgtgag
      781 cggggtgctg tctgatcaga tgagtgcccg ttggctcttc tcctctgggc tgctcctggt
      841 tggtctggtc aacgtagtct tctcgtggag ctctacagtg acggcttttg ctgctctctg
      901 gtttcttaat ggtctggcac aggggctagg ctggcccccc tgtgggaaga tcctgaggaa
      961 gtggtttgag ccatcccagt ttggcacttg gtgggctgtg ttgtcaacca gcatgaacct
     1021 ggctggaagc ctgggaccta tcttggcgac aatccttgct cagagctaca gctggcgcag
     1081 caccctggcc ctgtctgggt cactgtgtgt ggttgtctcc ttcttctgtc tgctgctcat
     1141 ccacaacgaa cctgctgatg ttggactccg aaatctggac cctgccccct ccaagggcaa
     1201 aaagggctcg tcaaaggagg agagcaccct acaggacctg ctgctgtccc cctatctctg
     1261 ggtgctctcc actggctacc tcgtggtctt tggggtaaag acttgctgta cagactgggg
     1321 ccagttcttc cttatccagg agagagggca gtcggccctc gtgggtagtt cctacatcag
     1381 tgccctagag gttggaggcc ttgtaggcag cattgcagct ggctatctgt cagacagggc
     1441 tatggcaaag gcagggctgt ctgtgtatgg gaaccctcgc cacagcctgt tgctgctcat
     1501 gatggctggc atggcagcat ccatgttcct cttccgggta acggtgacca gcgactcgcc
     1561 caagatctgg atcctggtgt tgggagccgt gtttggtttc tcttcttatg gtcccattgc
     1621 cttgtttgga gtcatagcta atgagagtgc acctcccaac ttgtgtggta cctctcatgc
     1681 tattgtgggg ctcatggcca atgtgggtgg atttctggct gggttaccct tcagtaccat
     1741 cgccaagcac tatagctgga gcacagcctt ctgggtggca gaagtgatct gtatagccag
     1801 cacagttgtc ttcttcttgc ttcgaaatat ccgcaccaag atgggccgag tatccaagaa
     1861 ggcagagtga aaagagcact cactatagag catccccaac tgcaacctca ttggcaggac
     1921 acagaaagga agagaggctg ctctggctag aacagagcct ttacatatct gtgtctacac
     1981 tgtctctctg gacctccgtg gtgctgcaag ttaccagtgg ctaatgaggt cctatgctct
     2041 atttaaatga tgtttggttt taggctccat tggcttctgt ttctaccttc tagcagacag
     2101 acaactccta aattcagggt gtctcctata cccctcttcc tctcctgagt ccccatctcc
     2161 tagtgaggtg gttctatctc tgcagctgca gaatattaat ggcctgtggt ttctgctgta
     2221 ccccaaggct tcttgttagg ggtcaacact gttgccaata cctcagtccc taagggagga
     2281 gaggaggcca ccactctcat cagtaccctg ggacaaaagg gaggaatgta gagagcaaac
     2341 tgtcttgtat agactaataa aactagattt gatactaaa
//
