LOCUS       NM_001033693            1763 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus solute carrier family 31 member 2 (Slc31a2),
            mRNA.
ACCESSION   NM_001033693 XM_216413
VERSION     NM_001033693.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1763)
  AUTHORS   Ohrvik,H., Nose,Y., Wood,L.K., Kim,B.E., Gleber,S.C., Ralle,M. and
            Thiele,D.J.
  TITLE     Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal
            transporter lacking the copper- and cisplatin-binding ecto-domain
  JOURNAL   Proc Natl Acad Sci U S A 110 (46), E4279-E4288 (2013)
   PUBMED   24167251
REFERENCE   2  (bases 1 to 1763)
  AUTHORS   Bertinato,J., Swist,E., Plouffe,L.J., Brooks,S.P. and L'abbe,M.R.
  TITLE     Ctr2 is partially localized to the plasma membrane and stimulates
            copper uptake in COS-7 cells
  JOURNAL   Biochem J 409 (3), 731-740 (2008)
   PUBMED   17944601
  REMARK    GeneRIF: Ctr2 promotes copper uptake at the plasma membrane and
            plays a role in regulating copper levels in COS-7 cells
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 24, 2010 this sequence version replaced NM_001033693.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.19477.1, CK365743.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000005.1  80753618-80753733
            117-183             JAXUCZ010000005.1  80759809-80759875
            184-372             JAXUCZ010000005.1  80761657-80761845
            373-374             JAXUCZ010000005.1  80762734-80762735
            375-1762            JAXUCZ010000005.1  80762736-80764123
FEATURES             Location/Qualifiers
     source          1..1763
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     gene            1..1763
                     /gene="Slc31a2"
                     /note="solute carrier family 31 member 2"
                     /db_xref="GeneID:298091"
                     /db_xref="RGD:1307963"
     exon            1..116
                     /gene="Slc31a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..542
                     /gene="Slc31a2"
                     /note="probable low affinity copper uptake protein 2;
                     solute carrier family 31 (copper transporters), member 2;
                     solute carrier family 31 (copper transporter), member 2"
                     /codon_start=1
                     /product="protein SLC31A2"
                     /protein_id="NP_001028865.2"
                     /db_xref="GeneID:298091"
                     /db_xref="RGD:1307963"
                     /translation="MPMHFIFSDEAVLLFDFWRVHSPTGMALSVLVVLLLAVLYEGIK
                     VGKAKLLHKTLESLPTTTSQQLILEPDQDSTGSRSTSDNRTRLRWFLCYFGQSLVHVI
                     QVVIGYFVMLAVMSYNTWIFLGVVLGSAVGYYLAYPLLHMT"
     exon            117..183
                     /gene="Slc31a2"
                     /inference="alignment:Splign:2.1.0"
     exon            184..373
                     /gene="Slc31a2"
                     /inference="alignment:Splign:2.1.0"
     exon            374..1763
                     /gene="Slc31a2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcgcggta gcagctgcaa tccgagtcga gtccggagtt gaatctcgag ctgagtcccg
       61 agcgggcgag cggactgacg cgacccgggc ggccgtctag tgggctcacc atgccgatgc
      121 acttcatctt ctcagatgag gctgtgcttc tctttgattt ctggagagtc cacagcccta
      181 caggcatggc tctctcagtg ctggtagtct tgctcctggc tgtattgtat gagggcatca
      241 aggttggcaa agccaagttg ctccacaaga ctctggagag cctgcctact accaccagcc
      301 agcagctcat cttggaacca gaccaggatt ctacaggctc cagatcaact tcagacaata
      361 ggacccgcct caggtggttt ttgtgttact ttggccagtc gctagtccat gtcattcagg
      421 tggtaattgg ctactttgtg atgctggctg tcatgtccta caacacctgg attttccttg
      481 gtgtggtcct gggctcggct gtgggctact acctagccta cccacttctc cacatgactt
      541 agtgggccag acatgtgcag tgctgagggc tggagagctg gggcctctgt tccaggcgtt
      601 gtacttcagc cgcctttcct taggatggca ctgctcacct cttccccagt tcctggtgac
      661 tgagatgaag ccagcaaagc cctggagctt agaagccatg gaagctactt ccctccccag
      721 cctatatagg gcccaggcct cctgtggttc cttacacaag tcgctgtgac caaagggaac
      781 atggagcgac cagaagctgg aggtagggtg gccagcctgt gacacagatc tctgactaca
      841 aattaaagtt ttccaaagag cttcagtgat aaaggccatg gaacctggac ctctcttctg
      901 ctttgtgcct taatgtcagg gcccgtctcc agtctttggg ggatggacca tgccagctcc
      961 ttgttctcac ctctttgcct tggaacacat gaggattgtc attgacagac tttacatttt
     1021 caactcctgg ttggcagttt tgcacattca tacaagacaa aatctctaat gaatttgcat
     1081 tcaagatgga tgcagggtct gttgagactt gtcttccctt ctccagggag gacggacgct
     1141 gattaaaggc agagagccag gactgtcaca gaggctgtag actcgtcttc tgtgcagatg
     1201 agctcttcct gtctgacagc actgcctgtg gcaggttagt ggtcagggcc cagcctgagc
     1261 ctcttgtatg caccacagag aacagcattt ggtaacagag atgaccaccc tgtattttta
     1321 cttcctgcta actcctaatg atctggtagg aaatgtgggt cagttactta gtactgactc
     1381 aacaggggtg tgctgggggc tgggtactga ctgggggtgc aataatagtc aaaccaaagc
     1441 taggtcgtgt caggggttaa gtggacttca gatatttgag ccttttcact ttacagagaa
     1501 aagagacagg aatggggcat agacctgtaa tctccagtat ctgggaggtg gaggcaggcg
     1561 attgtaactt tgaggccaga gagagttcca ggtcagcctg agatacacag tgaaacatac
     1621 acacacacat acacacgaca atcactgcta catactgtat aatgtctacg ttcaagtacc
     1681 tcatgggctc aatgaaaaga cggttttaag aagctttggg aattaaaaac aaacacacct
     1741 taataaattt ctatttttga aca
//
